The Woodward Selective Synthesis Group

B08, Carbon Neutral Laboratories

Woodward group tetracenes, some available from Key Organics (top) and a sample of our air-stable trimethylaluminium analogue “DABAL” weighed out on the bench (bottom, see: Key Organics Catalogue No. NS-00002, DABAL-Me3. Preferred supplier for larger quantities).

Prof. Woodward explains AlMe3 and DABAL-Me3 (video).

Welcome to the Woodward

Group…

Our small group’s current research concentrates on the identification of new compounds and processes using novel (often catalytic) reactions that cannot be attained with high efficiency using known chemistry. We aim to employ user-friendly, low cost, environmentally benign reagents in procedures that are simple to carry out and give added value products.

 

 

 

 

 

 

 

 

 

 

 

 

Recent contributions from the Woodward group: the key  transition state in Cu-catalysed 1,4-AlEt3 addition ACS Catalysis 2017 (editor’s choice article); rather active (GI50 around 1-2 µM) anti-cancer agents EJIC 2019 (joint with T. D. Bradshaw, Pharmacy, UoN); thermoelectric energy generation: Advanced Materials (joint with A. Steeger, F. Huewe, J. Pflaum, 2017).

Simon Woodward

A07, GSK Carbon Neutral Laboratories for Sustainable Chemistry

University of Nottingham

Jubilee Campus

Nottingham    NG7 2TU

United Kingdom

Tel: +44-(0)115-951-3541

FAX: +44-(0)115-951-3564

E-mail: simon.woodward@nottingham.ac.uk

To contact us:

Anne Floyde

CNL Administrator

Tel: +44-(0)115-748-6015

Fax: +44-(0)115-846-8459

E-mail: anne.floyde@nottingham.ac.uk

[only if you are having problems contacting Simon Woodward]

A sample of DABAL-Me3

Recent ‘key note’ publications:

Conjugate Addition Routes to 2-alkyl-2,3-dihydroquinolin-4(1H)-ones and 2-alkyl-4-hydroxy-1,2-dihydroquinoline-3-carboxylates A. Kingsbury; S. Brough; A. Pedrina McCarthy; W. Lewis; S. Woodward , Eur. J. Inorg. Chem. 2019, in press (link), awarded Very Important Paper (VIP) status and front cover article.

 

Syntheses of 7-Substituted Anthra[2,3-b]thiophene Derivatives and

Naphtho[2,3-b:6,7-b’]dithiophene, M. Al-jumaili, S. Woodward, J. Org. Chem. 2018, 83, 11437-11445 (link).

 

Synthesis and thermoelectric properties of 2- and 2,8-substituted tetrathiotetracenes, M. R. Garrett, M. J. Durán-Peña, William Lewis, K. Pudzs, J. Užulis, I. Mihailovs, B. Tyril,   J. Shine, E. F. Smith, M. Rutkis, S. Woodward,

J. Mater. Chem. C. 2018, 6, 3403-3409 (link).

 

Kinetic Analysis of Copper(I)/Feringa-Phosphoramidite Catalysed AlEt3 1,4-Addition to Cyclohex-2-en-1-one, ACS Catalysis  2017, 7, 6901-6908 (link). Selected by the American Chemical Society as an “editor’s choice” in 2017 (21st September, link). UoN press release (link) and infographic (.pptx format, link).

 

Low-Cost and Sustainable Organic Thermoelectrics Based on Low-Dimensional Molecular Metals”, F. Huewe, A. Steeger, K. Kostova, L. Burroughs, I. Bauer, P. Strohriegl, V. Dimitrov, S. Woodward and J. Pflaum, Adv. Mater. 2017, 29, 1605682 (collaboration with J. Pflaum, Uni. Würzburg, link).

 

 

Available from...

Laboratory B08,

Lab office: +44-(0)115-9587063

Via Simon Woodward: Tel: +44-(0)115-951-3541

S. Woodward, link to youtube video

Efficient preparation of TMSCCl2Br and its use in dichlorocyclopropanation of electron deficient alkenes, D. S. Lee, M. J. Durán-Peña, L. Burroughs, S. Woodward Chem. Eur. J. 2016, 22, 7609-7616, ’hot paper’ (link). Reagents now available via Nottingham Research Chemicals (TMSCCl3, link; TMSCCl2Br, link).

The Woodward Group are based in the ‘cutting edge’ CNL facility for sustainable chemistry

Photo of CNL1Photo of CNL2

with J. Pflaum group

(Uni. Würzburg)

Picture of Woodward tetracenesImage result for ACS Catalysis

Postdoctoral Position  in Synthetic Organic Chemistry (from 01 May, 2020), deadline 10 March, 2002. Details at (link).