Dov Stekel

Contact

• workRoom C19 Gateway Building
  Sutton Bonington Campus
  Sutton Bonington
  Leicestershire
  LE12 5RD
  UK
• work0115 951 6294
• dov.stekel@nottingham.ac.uk
• http://dovlab.wordpress.com

Selected Publications

• MA, HANSONG, HAGEN, FERRY, STEKEL, DOV J, JOHNSTON, SIMON A, SIONOV, EDWARD, FALK, RAMA, POLACHECK, ITZHACK, BOEKHOUT, TEUN and MAY, ROBIN C, 2009. The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation. Proceedings of the National Academy of Sciences of the United States of America. 106(31), 12980-5
• WELHAM, PATRICIA A and STEKEL, DOV J, 2009. Mathematical model of the Lux luminescence system in the terrestrial bacterium Photorhabdus luminescens. Molecular bioSystems. 5(1), 68-76

• View all publications

• HERBERT JMJ, STEKEL DJ, MURA M, SYCHEV M and BICKNELL R, 2011. Bioinformatic Methods For Finding Differentially Expressed Genes In Cdna Libraries, Applied To The Identification Of Tumour Vascular Targets. Methods In Molecular Biology (Clifton, N.J.). 729, 99-119
• HERMAN D, THOMAS CM and STEKEL DJ, 2011. Global Transcription Regulation Of Rk2 Plasmids: A Case Study In The Combined Use Of Dynamical Mathematical Models And Statistical Inference For Integration Of Experimental Data And Hypothesis Exploration. Bmc Systems Biology. 5, 119
• HERMAN, D, THOMAS, CM and STEKEL, DJ, 2011. Global Transcription Regulation Of Rk2 Plasmids: A Case Study In The Combined Use Of Dynamical Mathematical Models And Statistical Inference For Integration Of Experimental Data And Hypothesis Exploration Bmc Systems Biology. 5, -
• JENKINS, DAFYD J and STEKEL, DOV J, 2010. De Novo Evolution of Complex, Global and Hierarchical Gene Regulatory Mechanisms. Journal of molecular evolution. 71, 128-140
• GASSON, P., MILLER, R., STEKEL, D.J, WHINDER, F. and ZIEMINSKA, Z., 2010. Wood identification of Dalbergia nigra (CITES Appendix I) using quantitative wood anatomy, principal components analysis and naive Bayes classification. Annals of botany. 105(1), 45-56
• SALAMA, RAFIK A and STEKEL, DOV J, 2010. Inclusion of neighboring base interdependencies substantially improves genome-wide prokaryotic transcription factor binding site prediction. Nucleic acids research. 38(12), e135
• JENKINS, DAFYD J and STEKEL, DOV J, 2010. Stochasticity Versus Determinism: Consequences for Realistic Gene Regulatory Network Modelling and Evolution. Journal of molecular evolution. 70, 215-231
• FERNANDO, CHRISANTHA T, GOLDSTEIN, RICHARD A, HUSBANDS, PHIL and STEKEL, DOV J, 2010. In silico biology. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 477-80
• SALAMA, RA and STEKEL, DJ, 2010. Inclusion Of Neighboring Base Interdependencies Substantially Improves Genome-Wide Prokaryotic Transcription Factor Binding Site Prediction Nucleic Acids Research. 38(12), -
• JENKINS, DAFYD J and STEKEL, DOV J, 2009. A new model for investigating the evolution of transcription control networks. Artificial Life. 15(3), 259-91
• LEADBEATER, BARRY S C, YU, QIBIN, KENT, JOYCE and STEKEL, DOV J, 2009. Three-dimensional images of choanoflagellate loricae. Proceedings of the Royal Society B: Biological Sciences. 276(1654), 3-11
• WELHAM, PATRICIA A and STEKEL, DOV J, 2009. Mathematical model of the Lux luminescence system in the terrestrial bacterium Photorhabdus luminescens. Molecular bioSystems. 5(1), 68-76
• MA, HANSONG, HAGEN, FERRY, STEKEL, DOV J, JOHNSTON, SIMON A, SIONOV, EDWARD, FALK, RAMA, POLACHECK, ITZHACK, BOEKHOUT, TEUN and MAY, ROBIN C, 2009. The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation. Proceedings of the National Academy of Sciences of the United States of America. 106(31), 12980-5
• CHAUDHURI, ROY R, PETERS, SARAH E, PLEASANCE, STEPHEN J, NORTHEN, HELEN, WILLERS, CHRISSIE, PATERSON, GAVIN K, CONE, DANIELLE B, ALLEN, ANDREW G, OWEN, PAUL J, SHALOM, GIL, STEKEL, DOV J and CHARLES, IAN, 2009. Comprehensive identification of Salmonella enterica serovar typhimurium genes required for infection of BALB/c mice. PLoS pathogens. 5(7), e1000529
• FERNANDO, CHRISANTHA T, LIEKENS, ANTHONY M L, BINGLE, LEWIS E H, BECK, CHRISTIAN, LENSER, THORSTEN, STEKEL, DOV J and ROWE, JONATHAN E, 2009. Molecular circuits for associative learning in single-celled organisms. Journal Of The Royal Society Interface. 6(34), 463-9
• BACARDIT, J, STOUT, M, HIRST, JD, VALENCIA, A, SMITH, RE and KRASNOGOR, N, 2009. Automated Alphabet Reduction For Protein Datasets Bmc Bioinformatics. 10, -
• WELHAM, PA and STEKEL, DJ, 2009. Mathematical Model Of The Lux Luminescence System In The Terrestrial Bacterium Photorhabdus Luminescens Molecular Biosystems. 5(1), 68-76
• CHAUDHURI, R. R., LOMAN, N. J., SNYDER, L. A., BAILEY, C. M., STEKEL, D. J. and PALLEN, M. J., 2008. xBASE2: a comprehensive resource for comparative bacterial genomics. VOL 36(SUPP/1), D543-D546
• STEKEL, DOV J and JENKINS, DAFYD J, 2008. Strong negative self regulation of prokaryotic transcription factors increases the intrinsic noise of protein expression. BMC systems biology. 2, 6
• HERBERT, JOHN M J, STEKEL, DOV, SANDERSON, SHARON, HEATH, VICTORIA L and BICKNELL, ROY, 2008. A novel method of differential gene expression analysis using multiple cDNA libraries applied to the identification of tumour endothelial genes. BMC Genomics. 9, 153
• JENKINS, D.J. AND STEKEL. D.J., 2008. Effects of signalling on the evolution of gene regulatory networks In: Proceedings of the Eleventh International Conference on the Simulation and Synthesis of Living Systems. 289-296
• CHAUDHURI RR, LOMAN NJ, SNYDER LAS, BAILEY CM, STEKEL DJ and PALLEN MJ, 2008. Xbase2: A Comprehensive Resource For Comparative Bacterial Genomics. Nucleic Acids Research. 36(Database issue), D543-6
• BOWLES, EMMA J, LEE, JOON-HEE, ALBERIO, RAMIRO, LLOYD, RHIANNON E I, STEKEL, DOV, CAMPBELL, KEITH H S and ST JOHN, JUSTIN C, 2007. Contrasting effects of in vitro fertilization and nuclear transfer on the expression of mtDNA replication factors. Genetics. 176(3), 1511-26
• JONES, B, STEKEL, D.J, ROWE, J and FERNANDO, C.T., 2007. Is there a Liquid State Machine in the Bacterium Escherichia Coli? In: Proceedings of IEEE Symposium on Artificial Life. 187-191
• STEKEL, DOV J, SARTI, DONATELLA, TREVINO, VICTOR, ZHANG, LIHONG, SALMON, MIKE, BUCKLEY, CHRIS D, STEVENS, MARK, PALLEN, MARK J, PENN, CHARLES and FALCIANI, FRANCESCO, 2005. Analysis of host response to bacterial infection using error model based gene expression microarray experiments. Nucleic Acids Research. 33(6), e53
• STEKEL, D.J., 2003. Microarray Bioinformatics Cambridge University Press.
• STEKEL, D J, GIT, Y and FALCIANI, F, 2000. The comparison of gene expression from multiple cDNA libraries. Genome Research. 10(12), 2055-61
• SCHETTINO, G, FOLKARD, M, VOJNOVIC, B, MICHETTE, A.G, STEKEL, D.J, PFAUNTCSH, S.K and PRISE, K.M. AND MICHAEL, B.D., 2000. The ultrasoft X-ray microbeam: a sub-cellular probe of radiation response Radiation Research. 153, 222-225
• STEKEL, D J, 1998. The simulation of density-dependent effects in the recirculation of T lymphocytes. Scandinavian journal of immunology. 47(5), 426-30
• STEKEL, D J, PARKER, C E and NOWAK, M A, 1997. A model of lymphocyte recirculation. Immunology Today. 18(5), 216-21
• MAY, R M, STEKEL, D J and NOWAK, M A, 1997. Antigenic diversity thresholds and hazard functions. Mathematical Biosciences. 139(1), 59-68
• STEKEL, D J, 1997. The role of inter-cellular adhesion in the recirculation of T lymphocytes. Journal of Theoretical Biology. 186(4), 491-501
• RASHBASS, J, STEKEL, D and WILLIAMS, E D, 1996. The use of a computer model to simulate epithelial pathologies. Journal of Pathology. 179(3), 333-9
• STEKEL, D J, NOWAK, M A and SOUTHWOOD, T R, 1996. Prediction of future BSE spread. Nature. 381(6578), 119
• STEKEL, D, RASHBASS, J and WILLIAMS, E D, 1995. A computer graphic simulation of squamous epithelium. Journal of Theoretical Biology. 175(3), 283-93