Richard Argent

Contact

• workRoom C18 Main Building
  Sutton Bonington Campus
  Sutton Bonington
  Leicestershire
  LE12 5RD
  UK
• work0115 95 16308
• richard.argent@nottingham.ac.uk

Recent Publications

• YIN, Y., GRABOWSKA, A.M., CLARKE, P.A., WHELBAND, E., ROBINSON, K., ARGENT, R.H., TOBIAS, A., KUMARI, R., ATHERTON, J.C. and WATSON, S.A., 2010. Helicobacter pylori potentiates epithelial:mesenchymal transition in gastric cancer: links to soluble HB-EGF, gastrin and matrix metalloproteinase-7 Gut. 59(8), 1037-1045
• HUSSEIN, N.R., ARGENT, R.H., MARX, C.K., PATEL, S.R., ROBINSON, K. and ATHERTON, J.C., 2010. Helicobacter pylori dupA is polymorphic, and its active form induces proinflammatory cytokine secretion by mononuclear cells Journal of Infectious Diseases. 202(2), 261-269
• KENNY, S., DUVAL, C., SAMMUT, S.J., STEELE, I., PRITCHARD, D.M., ATHERTON, J.C., ARGENT, R.H., DIMALINE, R., DOCKRAY, G.J. and VARRO, A., 2008. Increased expression of the urokinase plasminogen activator system by Helicobacter pylori in gastric epithelial cells American Journal of Physiology: Gastrointestinal and Liver Physiology. 295(3), G431-G441
• ARGENT, R.H., THOMAS, R.J., LETLEY, D.P., RITTIG, M.G., HARDIE, K.R. and ATHERTON, J.C., 2008. Functional association between the Helicobacter pylori virulence factors VacA and CagA Journal of Medical Microbiology. 57(2), 145-150

• View all publications

• YIN, Y., GRABOWSKA, A.M., CLARKE, P.A., WHELBAND, E., ROBINSON, K., ARGENT, R.H., TOBIAS, A., KUMARI, R., ATHERTON, J.C. and WATSON, S.A., 2010. Helicobacter pylori potentiates epithelial:mesenchymal transition in gastric cancer: links to soluble HB-EGF, gastrin and matrix metalloproteinase-7 Gut. 59(8), 1037-1045
• HUSSEIN, N.R., ARGENT, R.H., MARX, C.K., PATEL, S.R., ROBINSON, K. and ATHERTON, J.C., 2010. Helicobacter pylori dupA is polymorphic, and its active form induces proinflammatory cytokine secretion by mononuclear cells Journal of Infectious Diseases. 202(2), 261-269
• KENNY, S., DUVAL, C., SAMMUT, S.J., STEELE, I., PRITCHARD, D.M., ATHERTON, J.C., ARGENT, R.H., DIMALINE, R., DOCKRAY, G.J. and VARRO, A., 2008. Increased expression of the urokinase plasminogen activator system by Helicobacter pylori in gastric epithelial cells American Journal of Physiology: Gastrointestinal and Liver Physiology. 295(3), G431-G441
• ARGENT, R.H., THOMAS, R.J., LETLEY, D.P., RITTIG, M.G., HARDIE, K.R. and ATHERTON, J.C., 2008. Functional association between the Helicobacter pylori virulence factors VacA and CagA Journal of Medical Microbiology. 57(2), 145-150
• HUSSEIN, N.R., MOHAMMADI, M., TALEBKHAN, Y., DORAGHI, M., LETLEY, D.P., MUHAMMAD, M.K., ARGENT, R.H. and ATHERTON, J.C., 2008. Differences in virulence markers between Helicobacter pylori strains from Iraq and those from Iran: potential importance of regional differences in H. pylori-associated disease Journal of Clinical Microbiology. 46(5), 1774-1779
• ARGENT, R.H., HALE, J.L., EL-OMAR, E.M. and ATHERTON, J.C., 2008. Differences in Helicobacter pylori CagA tyrosine phosphorylation motif patterns between western and East Asian strains, and influences on interleukin-8 secretion Journal of Medical Microbiology. 57(9), 1062-1067
• ARGENT, R.H., THOMAS, R.J., AVILES-JIMENEZ, F., LETLEY, D.P., LIMB, M.C., EL-OMAR, E.M. and ATHERTON, J.C., 2008. Toxigenic Helicobacter pylori infection precedes gastric hypochlorhydria in cancer relatives, and H. pylori virulence evolves in these families Clinical Cancer Research: an official journal of the American Association for Cancer Research. 14(7), 2227-2235
• ROBINSON, KAREN, ARGENT, RICHARD H and ATHERTON, JOHN C, 2007. The inflammatory and immune response to Helicobacter pylori infection. Best Practice & Research Clinical Gastroenterology. 21(2), 237-59
• ARGENT, RICHARD H, BURETTE, ALAIN, MIENDJE DEYI, VÉRONIQUE Y and ATHERTON, JOHN C, 2007. The presence of dupA in Helicobacter pylori is not significantly associated with duodenal ulceration in Belgium, South Africa, China, or North America. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 45(9), 1204-6
• REYES-LEON, ADRIANA, ATHERTON, JOHN C, ARGENT, RICHARD H, PUENTE, J L and TORRES, J, 2007. Heterogeneity in the Activity of Mexican Helicobacter pylori Strains in Gastric Epithelial Cells and Its Association with Diversity in the cagA Gene. Infection and Immunity. 75(7), 3445-54
• BOUGHAN, PARJEET K, ARGENT, RICHARD H, BODY-MALAPEL, MATHILDE, PARK, JONG-HWAN, EWINGS, KATIE E, BOWIE, ANDREW G, ONG, SHAO JIN, COOK, SIMON J, SORENSEN, OLE E, MANZO, BARBARA A, INOHARA, NAOHIRO and KLE, 2006. Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: critical regulators of beta-defensins during Helicobacter pylori infection. The Journal of biological chemistry. 281(17), 11637-48
• ARGENT, RICHARD H, ZHANG, YOULI and ATHERTON, JOHN C, 2005. Simple method for determination of the number of Helicobacter pylori CagA variable-region EPIYA tyrosine phosphorylation motifs by PCR. Journal of clinical microbiology. 43(2), 791-5
• ZHANG, YOULI, ARGENT, RICHARD H, LETLEY, DARREN P, THOMAS, RACHAEL J and ATHERTON, JOHN C, 2005. Tyrosine phosphorylation of CagA from Chinese Helicobacter pylori isolates in AGS gastric epithelial cells. Journal of Clinical Microbiology. 43(2), 786-90
• ARGENT, R.H., KIDD, M., OWEN, R.J., THOMAS, R.J., LIMB, M.C. and ATHERTON, J.C., 2004. Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori Gastroenterology. 127(2), 514-523
• ARGENT, R. H., MCGARR, C. and ATHERTON, J. C., 2004. Brefeldin A enhances Helicobacter pylori vacuolating cytotoxin-induced vacuolation of epithelial cells FEMS Microbiology Letters. VOL 237(NUMBER 1), 163-170
• THOMAS, R.J., ARGENT, R.H., LETLEY, D.P., HARDIE, K.R. and ATHERTON, J.C., 2003. Interaction between the Helicobacter pylori virulence factors CagA and VacA Gastroenterology. 124(4), A272-A272
• ARGENT, R.H., KIDD, M., OWEN, R.J., LIMB, M.C. and ATHERTON, J.C., 2003. PCR detection of Cag pathogenicity island genes does not accurately predict functionality of Cag encoded proteins Gut. 52, 62
• ARGENT, R.H., KIDD, M., OWEN, R.J., LIMB, M.C. and ATHERTON, J.C., 2003. The number of phosphorylation sites within the cagA gene of Helicobacter pylori may determine disease outcome in infected patients Gastroenterology. 124(4), A52-A52
• ARGENT, R.H., MCGARR, C. and ATHERTON, J.C., 2002. Beyond the vacuole. Trafficking of VacA from Helicobacter pylori within epithelial cells Gut. 51, 309
• WESTBY, M, ARGENT, R H, PITCHER, C, LORD, J M and ROBERTS, L M, Preparation and characterization of recombinant proricin containing an alternative protease-sensitive linker sequence. Bioconjugate chemistry. 3(5), 375-81