Sivakumar Manickam

Contact

• workRoom CLG11 C
  Malaysia Campus
  Jalan Broga
  43500 Semenyih
  Selangor Darul Ehsan
  Malaysia
• work+6 (03) 8924 8156
• fax+6 (03) 8924 8017
• sivakumar.manickam@nottingham.edu.my
• http://www.nottingham.edu.my/Engineering/Departments/Chemenv/People/sivakumar.manickam

Teaching Summary

· Chemical Product Design

· Modern Process Chemistry

· Waste and Wastewater Treatment

· Nanotechnology of Advanced Materials

· Pharmaceutical Chemical Engineering & Technology · Technology of Fine Chemicals and Bulk Drugs · Chemical Process Technology · Chemical Engineering Operations · Modern Analytical Techniques · Unit Processes in organic Synthesis · Novel Drug Delivery Systems

Research Summary

Nano chemical engineering of Advanced Materials; Development of Nanosuspensions and Nanoemulsions for Pharmaceutical Industries; Process Research, Engineering and Development of Drugs and Drug… read more

Selected Publications

• PRAKASH ANJANAPPA, DIBAKAR MULLICK, KUMARAVEL SELVAKUMAR, KANDASAMY RUCKMANI AND MANICKAM SIVAKUMAR, 2011. Efficient indoles and anilines syntheses employing tert-butyl sulfinamide as ammonia surrogate Tetrahedron Letters. 52(43), 5625-5628
• DIBAKAR MULLICK, PRAKASH ANJANAPPA, KUMARAVEL SELVAKUMAR, KANDASAMY RUCKMANI AND MANICKAM SIVAKUMAR, 2011. 2-(Trimethylsilyl)ethanol as a new alcohol equivalent for copper-catalyzed coupling of aryl iodides Tetrahedron Letters. 52(41), 5338-5341
• MANICKAM SIVAKUMAR, ATSUYA TOWATA, KYUICHI YASUI, TORU TUZIUTI, TERUYUKI KOZUKA, MASAHIKO TSUJIMOTO, ZIYI ZHONG AND YASUO IIDA, 2010. Fabrication of Nanosized Pt on rutile TiO2 using a standing wave sonochemical reactor (SWSR) – Observation of an enhanced catalytic oxidation of CO Ultrasonics Sonochemistry. 17(1), 213-218
• MANICKAM SIVAKUMAR, KYUICHI YASUI, TORU TUZIUTI, ATSUYA TOWATA AND YASUO IIDA, 2010. Dependence of sonochemical parameters on the platinization of rutile titania and their photocatalytic efficiencies Ultrasonics Sonochemistry. 17(3), 621-627

• View all publications

Current Research

Nano chemical engineering of Advanced Materials; Development of Nanosuspensions and Nanoemulsions for Pharmaceutical Industries; Process Research, Engineering and Development of Drugs and Drug Intermediates; Utilisation of Highly Energy Efficient Ultrasonic and Hydrodynamic Cavitation Technique for the Development of Nanomaterials as well as for Waste-water Treatment

• SIAH YING TANG, MANICKAM SIVAKUMAR, TAN KHANG WEI AND NASHIRU BILLA, 2012. Formulation Development and Optimization of a Novel Cremophore EL-based Nanoemulsion using Ultrasound Cavitation Ultrasonics Sonochemistry. 19(2), 330-45
• VIGNESH M, SIVAKUMAR, M, PARKAVI V, SELVAKUMAR K AND JOYSA RUBY J, 2012. Stabilisation of Folic acid in liquid dosage form: Formulation development, method validation and comparative analysis International Journal of Pharmaceutical and Chemical Sciences. 1(1), 332-338
• LAY HONG CHUAH, NASHIRU BILLA, CLIVE J ROBERTS, JONATHAN C BURLEY AND SIVAKUMAR MANICKAM, 2012. Curcumin-containing Chitosan nanoparticles as a potential Mucoadhesive delivery system to the colon Pharmaceutical Development and Technology.
• MANICKAM SIVAKUMAR, ATSUYA TOWATA, KYUICHI YASUI, TORU TUZIUTI, T. KOZUKA, YASUO IIDA, MICHAIL M. MAIOROV, ELMARS BLUMS, NEELAGESI SIVAKUMAR AND M. ASHOK, 2012. Ultrasonic Cavitation induced Water in Vegetable oil Emulsion droplets - A Simple and Easy Technique to Synthesize Manganese Zinc Ferrite Nanocrystals with improved magnetization Ultrasonics Sonochemistry. 19(3), 652-658
• TAN KHANG WEI AND SIVAKUMAR MANICKAM, 2012. Response Surface Methodology, an Effective Strategy in the Optimisation of the preparation of Curcumin-loaded Nanoemulsion Asia-Pacific Journal of Chemical Engineering. 7(S1), S125-S133
• SIAH YING TANG AND MANICKAM SIVAKUMAR, 2012. Design and evaluation of aspirin-loaded water-in-oil-in-water submicron multiple emulsions generated using two-stage ultrasonic cavitational emulsification technique Asia-Pacific Journal of Chemical Engineering. 7(S1), S145–S156
• SIAH YING TANG, MANICKAM SIVAKUMAR, ANGELA MIN-HWEI NG AND PARTHASARATHY SHRIDHARAN, 2012. Anti-inflammatory and Analgesic activity of novel oral Aspirin-loaded Nanoemulsion and Nano multiple emulsion formulations generated using Ultrasound Cavitation International Journal of Pharmaceutics. 430(1-2), 299-306
• DIBAKAR MULLICK, PRAKASH ANJANAPPA, KUMARAVEL SELVAKUMAR, KANDASAMY RUCKMANI AND MANICKAM SIVAKUMAR, 2011. 2-(Trimethylsilyl)ethanol as a new alcohol equivalent for copper-catalyzed coupling of aryl iodides Tetrahedron Letters. 52(41), 5338-5341
• PRAKASH ANJANAPPA, DIBAKAR MULLICK, KUMARAVEL SELVAKUMAR, KANDASAMY RUCKMANI AND MANICKAM SIVAKUMAR, 2011. Efficient indoles and anilines syntheses employing tert-butyl sulfinamide as ammonia surrogate Tetrahedron Letters. 52(43), 5625-5628
• SIAH YING TANG AND MANICKAM SIVAKUMAR, 2010. A Novel Formulation and Optimisation of Aspirin Nanoemulsion prepared by Cavitation induced by ultrasonic waves Journal of Industrial Technology. 19(1), 179-196
• MANICKAM SIVAKUMAR, ATSUYA TOWATA, KYUICHI YASUI, TORU TUZIUTI, TERUYUKI KOZUKA, MASAHIKO TSUJIMOTO, ZIYI ZHONG AND YASUO IIDA, 2010. Fabrication of Nanosized Pt on rutile TiO2 using a standing wave sonochemical reactor (SWSR) – Observation of an enhanced catalytic oxidation of CO Ultrasonics Sonochemistry. 17(1), 213-218
• DIBAKAR MULLICK, PRAKASH ANJANAPPA, KUMARAVEL SELVAKUMAR, KANDASAMY RUCKMANI AND MANICKAM SIVAKUMAR, 2010. Carbamic acid 2-trimethylsilylethyl ester as new ammonia equivalent for palladium catalyzed amination of aryl halides Tetrahedron Letters. 51(46), 5984-5987
• and RUCKMANI K, SANKAR M AND SIVAKUMAR M, 2010. Tissue distribution, Pharmacokinetics, and Stability studies of Zidovudine delivered by Niosomes and Proniosomes Journal of Biomedical Nanotechnology. 6(1), 43-51
• BHASKAR RAO REDDY, THIRUGNANASAMBANDAM SIVASANKAR, MANICKAM SIVAKUMAR AND VIJAYANAND MOHOLKAR, 2010. Physical facets of Ultrasonic cavitational synthesis of Zinc ferrite particles Ultrasonics Sonochemistry. 17(2), 416-426
• MANICKAM SIVAKUMAR, KYUICHI YASUI, TORU TUZIUTI, ATSUYA TOWATA AND YASUO IIDA, 2010. Dependence of sonochemical parameters on the platinization of rutile titania and their photocatalytic efficiencies Ultrasonics Sonochemistry. 17(3), 621-627
• ATSUYA TOWATA, MANICKAM SIVAKUMAR, KYUICHI YASUI, TORU TUZIUTI, TERUYUKI KOZUKA AND YASUO IIDA, 2008. Synthesis of europium-doped yttrium hydroxide and yttrium oxide nanosheets Journal of Materials Science. 43(4), 1214-1219
• PRAKASH ANJANAPPA, DIBAKAR MULLICK, KUMARAVEL SELVAKUMAR AND MANICKAM SIVAKUMAR, 2008. 2-(Trimethylsilyl)ethanesulfonyl amide as new ammonia equivalent for palladium catalyzed amination of aryl halides Tetrahedron letters. 49(31), 4585-4587
• ATSUYA TOWATA, MANICKAM SIVAKUMAR, KYUICHI YASUI, TORU TUZIUTI, TERUYUKI KOZUKA AND YASUO IIDA, 2007. Ultrasound induced formation of Paraffin Emulsion droplets as template for the preparation of porous zirconia Ultrasonics Sonochemistry. 14(6), 705-710
• RUCKMANI, K, SIVAKUMAR, M and SATHEESH KUMAR, S., 2007. Nanoparticular Drug Delivery System of Cytarabine Hydrochloride (CTH) for Improved Treatment of Lymphoma Journal of Biomedical Nanotechnology. 3, 1-7
• T. TUZIUTI, K.YASUI, M.SIVAKUMAR AND Y.IIDA, 2006. Influence of dissolved-air concentration on spatial distribution of bubbles for sonochemistry Ultrasonics. 44, e357
• M.SIVAKUMAR, K.YASUI, A. TOWATA, T. TUZIUTI AND Y.IIDA, 2006. A New Ultrasonic Cavitation approach for the Synthesis of Zinc Ferrite Nanocrystals Current Applied Physics. 6(3), 591
• SIVAKUMAR, M, TOWATA, A, YASUI, K, TUZIUTI, T and IIDA, Y., 2006. Ultrasonic Cavitational Activation: A Simple and Feasible route for the direct conversion of zinc acetate to highly monodispersed ZnO Chemistry Letters. 35(1), 60
• MAZUMDER, R, GHOSH, S, MONDAL, P, BHATTACHARYA, D, DASGUPTA, S, DAS, N, SEN, A, TYAGI, A.K, SIVAKUMAR, M, TAKAMI, T and IKUTA, H., 2006. Particle size dependence of magnetization and phase transition near TN in multiferroic BiFeO3 Journal of Applied Physics. 100, 033908
• RUCKMANI, K, SIVAKUMAR, M and GANESHKUMAR, P.A., 2006. Solid Lipid Nanoparticles (SLN) - A Novel Carrier System for Antitumour Drugs – Characterization, In-Vitro & In-Vivo Studies Journal of Nanoscience and Nanotechnology. 6(8), 1-5
• SIVAKUMAR, M, TAKAMI, T, IKUTA, H, BHATTACHARYA, D, YASUI, K, TOWATA, A, TUZIUTI, T and IIDA, Y., 2006. Fabrication of Zinc Ferrite Nanocrystals by Sonochemical activation - Observation of Magnetization and its relaxation at low temperature Journal of Physical Chemistry B. 110(31), 15234-15243
• SIVAKUMAR, M and GEDANKEN, A., 2006. Acoustic Cavitation – An Efficient tool to synthesize Nanosized CuO-ZrO2 Catalysts with Mesoporous distribution New Journal of Chemistry. 30(1), 102-107
• TORU.TUZIUTI, KYUICHIYASUI, YASUO IIDA AND MANICKAM SIVAKUMAR, 2005. Correlation between Acoustic Cavitation Noise and Yield enhancement of Sonochemical reaction by particle addition Journal of Physical Chemistry A. 109(21), 4869
• MANICKAM SIVAKUMAR, KATSURO TACHIBANA, ANIRUDDHA B. PANDIT, KYUICHI YASUI, TORU TUZIUTI, ATSUYA TOWATA AND YASUO IIDA, 2005. Transdermal Drug Delivery using Ultrasound – Theory, Understanding and a Critical Analysis Cellular and Molecular Biology. 51, OL 767
• A.TOWATA, M.SIVAKUMAR, K.YASUI, T.TUZIUTI, T.KOZUKA AND Y.IIDA, 2005. Synthesis of alumina macroporous materials using yeast cells as biotemplates Journal of the Ceramic Society of Japan. 113, 696
• A.TOWATA, M.SIVAKUMAR, K.YASUI, T.TUZIUTI, T.KOZUKA, K.OHTA AND Y.IIDA, 2005. Fabrication of bimodal (meso/macro) porous alumina materials using yeast cells as templates E-Journal of Surface Science and Nanotechnology. 3, 405-411
• K.YASUI, T.TUZIUTI, M.SIVAKUMAR AND Y.IIDA, 2005. Theoretical study of Single-bubble Sonochemistry Journal of Chemical Physics. 122, 224706
• Y.IIDA, K.YASUI, T.TUZIUTI AND M.SIVAKUMAR, 2005. Sonochemistry and its Dosimetry Microchemical Journal. 80, 159
• M.SIVAKUMAR AND A. GEDANKEN, 2005. A Sonochemical method for the synthesis of Polyaniline and Au-polyaniline composites using H2O2 for enhancing rate and yield Synthetic Metals. 148(3), 301
• M.SIVAKUMAR, A. GEDANKEN, W. ZHONG, H.Y.JIANG, Y.W. DU, D.BHATTACHARYA, I.BRUKENTAL, Y.YESHURUN AND A.FELNER, 2004. Distinctive and Multiadvantageous Sonochemical method for the synthesis of Nanocrystalline Rare Earth Ferrites using a Novel Fe(CO)5 precursor Chemistry of Materials. 16, 3623-32
• M.SIVAKUMAR, A. GEDANKEN, W. ZHONG, Y.W. DU AND A.FELNER, 2004. Sonochemical Synthesis of Nanocrystalline LaFeO3 Journal of Materials Chemistry. 14(4), 764-769
• M.SIVAKUMAR, A. GEDANKEN, W. ZHONG, Y.W. DU, D.BHATTACHARYA, Y.YESHURUN AND A.FELNER, 2004. Nanophase Formation of Strontium Hexaferrite Fine Powder by the Sonochemical method using Fe(CO)5 Journal of Magnetism and Magnetic Materials. 268((1-2)), 95-104
• M.SIVAKUMAR, Y.IIDA, K.YASUI AND T.TUZIUTI, 2004. Preparation of nanosized TiO2 supported on Activated alumina by a Sonochemical method – Observation of an increased Photocatalytic Decolourisation efficiency Research on Chemical Intermediates. 7(8), 785
• Y.IIDA, K.YASUI, T.TUZIUTI, M.SIVAKUMAR AND Y.ENDO, 2004. Ultrasonic Cavitation in microspace Chemical Communications. 2280-2281
• TORU.TUZIUTI, KYUICHIYASUI, YASUO IIDA, MANICKAM SIVAKUMAR AND SHINOBU KODA, 2004. Laser-Light Scattering from a Multibubble system for Sonochemistry Journal of Physical Chemistry A. 108, 9011
• P.R. GOGATE, M.SIVAKUMAR AND ANIRUDDHA B.PANDIT, 2004. Destruction of Rhodamine B using novel sonochemical reactor with capacity of 7.5 L Separation and Purification Technology. 34((1-3)), 13-24
• M.SIVAKUMAR AND A. GEDANKEN, 2004. Insights into the Sonochemical Decomposition of Fe(CO)5 : Theoretical and Experimental nderstanding of the role of Molar Concentration and Power Density on the Reaction Yield Ultrasonics Sonochemistry. 11(6), 373-378
• T.TUZIUTI, K.YASUI, Y.IIDA AND M.SIVAKUMAR, 2004. Correlation in Spatial Intensity Distribution between volumetric bubbles Oscillation and Sonoluminescence in a Multibubble system Research on Chemical Intermediates. 7(8), 755
• K.YASUI, T.TUZIUTI, M.SIVAKUMAR AND Y.IIDA, 2004. Sonoluminescence Applied Spectroscopy Reviews. 39(3), 399-436
• M.SIVAKUMAR, P.SENTHILKUMAR, SUKTI MAJUMDAR AND A.B.PANDIT, 2002. Ultrasound mediated Alkaline Hydrolysis of Methyl Benzoate : Reinvestigation with crucial parameters Ultrasonics Sonochemistry. 9(1), 25-30
• M.SIVAKUMAR, P.A.TATAKE AND A.B.PANDIT, 2002. Kinetics of p-Nitrophenol degradation: Effect of Reaction conditions and Cavitational parameters for a Multiple Frequency system Chemical Engineering Journal. 85((2-3)), 327-338
• M.SIVAKUMAR AND A.B.PANDIT, 2002. Wastewater Treatment: A novel energy efficient Hydrodynamic Cavitational technique Ultrasonics Sonochemistry. 9(3), 123-131
• M.SIVAKUMAR AND A.B.PANDIT, 2001. Ultrasound Enhanced Degradation of Rhodamine B:Optimisation with Power Density Ultrasonics Sonochemistry. 8(3), 233-240
• M.SIVAKUMAR, P.SENTHILKUMAR AND A.B.PANDIT, 2001. Ultrasound Enhanced PTC Conversion of Benzamide to Benzonitrile Synthetic Communications. 31(17), 2583-2587
• PARAG R.GOGATE, SHIRGAONKAR, I.Z., M.SIVAKUMAR, P.SENTHILKUMAR AND ANIRUDDHA.B.PANDIT, 2001. Cavitation Reactors : Efficiency assessment using a model reaction American Institute of Chemical Engineering Journal (AIChEJ). 47(11), 2526-2538
• P.SENTHILKUMAR, M.SIVAKUMAR AND A.B.PANDIT, 2000. Experimental Quantification of Chemical Effects of Hydrodynamic Cavitation Chemical Engineering Science. 55(9), 1633-39
• A.B.PANDIT, P.SENTHILKUMAR AND M.SIVAKUMAR, 1999. Improve Reactions with Hydrodynamic Cavitation Chemical Engineering Progress. 33,
• TOWATA, A, SIVAKUMAR, M, YASUI, K, TUZIUTI, T, KOZUKA, T and IIDA, Y., Ultrasound induced formation of Paraffin Emulsion droplets as template for the preparation of porous zirconia Ultrasonics Sonochemistry. (In Press.)