PYGALL, SAMUEL R, GRIFFITHS, PETER C, WOLF, BETTINA, TIMMINS, PETER and MELIA, COLIN D, 2011. Solution interactions of diclofenac sodium and meclofenamic acid sodium with hydroxypropyl methylcellulose (HPMC). International journal of pharmaceutics. 405(1-2), 55-62 WILLIAMS HD, NOTT KP, BARRETT DA, WARD R, HARDY IJ and MELIA CD, 2011. Drug Release From HPMC Matrices In Milk And Fat-Rich Emulsions. Journal Of Pharmaceutical Sciences. 100(11), 4823-35 WILLIAMS, HYWEL D, BARRETT, DAVID A, WARD, ROBERT, HARDY, IAN J and MELIA, COLIN D, 2010. A liquid chromatography method for quantifying caffeine dissolution from pharmaceutical formulations into colloidal, fat-rich media. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 878(21), 1739-45 CREAN, BARRY, PARKER, ANDREW, ROUX, DELPHINE LE, PERKINS, MARK, LUK, SHEN Y, BANKS, SIMON R, MELIA, COLIN D and ROBERTS, CLIVE J, 2010. Elucidation of the internal physical and chemical microstructure of pharmaceutical granules using X-ray micro-computed tomography, Raman microscopy and infrared spectroscopy. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V. 76(3), 498-506
WILLIAMS, HYWEL D, WARD, ROBERT, CULY, ANNA, HARDY, IAN J and MELIA, COLIN D, 2010. Designing HPMC matrices with improved resistance to dissolved sugar. International journal of pharmaceutics. 401(1-2), 51-9 WILLIAMS, HYWEL D, WARD, ROBERT, HARDY, IAN J and MELIA, COLIN D, 2010. The effect of sucrose and salts in combination on the drug release behaviour of an HPMC matrix. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V. 76(3), 433-6
CREAN, B., CHEN, X., BANKS, S.R., COOK, W.G., MELIA, C.D. and ROBERTS, C.J., 2009. An Investigation into the Rheology of Pharmaceutical Inter-granular Material Bridges at High Shear Rates Pharmaceutical Research. 26, 1101-1111 BOYD, M. J., HAMPSON, F. C., JOLLIFFE, I. G., DETTMAR, P. W., MITCHELL, J. R. and MELIA, C. D., 2009. Strand-like phase separation in mixtures of xanthan gum with anionic polyelectrolytes Food Hydrocolloids. VOL 23(NUMBER 8), 2458-2467 WILLIAMS, HYWEL D, WARD, ROBERT, HARDY, IAN J and MELIA, COLIN D, 2009. The extended release properties of HPMC matrices in the presence of dietary sugars. Journal of controlled release : official journal of the Controlled Release Society. 138(3), 251-9 BAJWA, G. S., SAMMON, C., TIMMINS, P. and MELIA, C. D., 2009. Molecular and mechanical properties of hydroxypropyl methylcellulose solutions during the sol:gel transition POLYMER -LONDON-. VOL 50(NUMBER 19), 4571-4576
PYGALL, SAMUEL R, KUJAWINSKI, SARAH, TIMMINS, PETER and MELIA, COLIN D, 2009. Mechanisms of drug release in citrate buffered HPMC matrices. International journal of pharmaceutics. 370(1-2), 110-20
C D MELIA, B CREAN, SR PYGALL and HD WILLIAMS, 2009. New imaging methods for dosage form characterisation. In: AT FLORENCE and J SEIPMANN, eds., Modern Pharmaceutics 5th. volume 2. Informa healthcare. 299-420
BAJWA, G.S., HOEBLER, K., SAMMON, C., TIMMINS, P. and MELIA, C.D., 2006. Microstructural imaging of early gel layer formation in HPMC matrices Journal of Pharmaceutical Sciences. 95(10), 2145-2157 BOYD, M.J., MITCHELL, J.R., MELIA, C.D., DETTMAR, P.W., JOLLIFFE, I.G. and HAMPSON, F.C., 2006. Thickenable Compositions US2006078526-A1, WO2 01/01/1900 00:00:00
RICHARDSON, J.C., MELIA, C.D., STRUGALA, V. and DETTMAR, P.W., 2006. An overview of polysaccharide therapeutics and future directions. In: PHILLIPS, G.O. and WILLIAMS, P.A., eds., Gums and Stabilisers for the Food Industry 13. Royal Society of Chemistry. 476-490 RICHARDSON, J. C., FOSTER, C. S., DOUGHTY, S. W., BURTON, J. S., MACRAE, R. J. and MELIA, C. D., 2006. The influence of l-amino acid molecular structure on the phase transition temperature of hydroxypropyl methylcellulose CARBOHYDRATE POLYMERS. VOL 65(NUMBER 1), 22-27 RICHARDSON, J.C., MELIA, C.D., DETTMAR, P.W., JOLLIFFE, I.G. and HAMPSON, F.C., 2006. Bioadhesive liquid composition which is substantially free of water US2006292184, WO2004 01/01/1900 00:00:00
RICHARDSON, J CRAIG, DETTMAR, PETER W, HAMPSON, FRANK C and MELIA, COLIN D, 2005. Oesophageal bioadhesion of sodium alginate suspensions 2. Suspension behaviour on oesophageal mucosa. European Journal of Pharmaceutical Sciences. 24(1), 107-14 RICHARDSON, J.C., BOWTELL, R.W., MÄDER, K. and MELIA, C.D., 2005. Pharmaceutical applications of magnetic resonance imaging (MRI) Advanced Drug Delivery Reviews. 57(8), 1191-1209 BOYD, M.J., MITCHELL, J.R., HAMPSON, F.C., JOLLIFFE, I.G., DETTMAR, P.W. and MELIA, C.D., 2004. Phase separation behaviour in xanthan and sodium alginate mixtures. In: WILLIAMS, P.A. and PHILLIPS, G.O., eds., Gums and Stabilisers for the Food Industry 12 Cambridge: Royal Society of Chemistry. 262-271
MARSHALL, P., SNAAR, J.E., NG, Y.L., BOWTELL, R.W., HAMPSON, F.C., DETTMAR, P.W., ONSOYEN, E. and MELIA, C.D., 2004. Localised mapping of water movement and hydration inside a developing bioadhesive bond Journal of Controlled Release. 95(3), 435-446 HAN, JIHONG, DAVIS, STANLEY S, PAPANDREOU, CATHERINE, MELIA, COLIN D and WASHINGTON, CLIVE, 2004. Design and evaluation of an emulsion vehicle for paclitaxel. I. Physicochemical properties and plasma stability. Pharmaceutical Research. 21(9), 1573-80 RICHARDSON, J. C., DETTMAR, P. W., HAMPSON, F. C. and MELIA, C. D., 2004. A simple, high throughput method for the quantification of sodium alginates on oesophageal mucosa European Journal of Pharmaceutics and Biopharmaceutics. VOL 57(NUMBER 2), 299-305 RICHARDSON, J.C., MELIA, C.D., DETTMAR, P.W., HAMPSON, F.C. and JOLLIFFE, I.G., 2004. Liquid composition for treating or preventing inflammation 01/01/1900 00:00:00
RICHARDSON, J.C., DETTMAR, P.W., HAMPSON, F.C. and MELIA, C.D., 2004. The bioadhesive and swelling characteristics of sodium alginate suspensions. In: Gums and Stabilisers for the Food Industry 12. Royal Society of Chemistry, Cambridge, UK. 75-83
RICHARDSON, J CRAIG, DETTMAR, PETER W, HAMPSON, FRANK C and MELIA, COLIN D, 2004. Oesophageal bioadhesion of sodium alginate suspensions: particle swelling and mucosal retention. European Journal of Pharmaceutical Sciences. 23(1), 49-56 HAN, J., WASHINGTON, C. and MELIA, C. D., 2004. A concentric cylinder shear device for the study of stability in intravenous emulsions European Journal of Pharmaceutical Sciences. VOL 23(NUMBER 3), 253-260 SUTCH, J.C.D., ROSS, A.C., KÖCKENBERGER, W., BOWTELL, R.W., MACRAE, R.J., STEVENS, H.N.E and MELIA, C.D., 2003. Investigating the coating-dependent release mechanism of a pulsatile capsule using NMR microscopy Journal of Controlled Release. 92(3), 341-347 BOYD,M.J., MITCHELL,J.R., MELIA,C.D., JOLLIFFE,I.G., DETTMAR,P.W. and HAMPSON,F.C., 2003. Viscosity increasing compositions GB2401869-A 04/01/2003 00:00:00
BOYD,M.J., MITCHELL,J.R., MELIA,C.D., JOLLIFFE,I.G., DETTMAR,P.W. and HAMPSON,F.C., 2003. Viscosity increasing compositions GB2401869-A 04/01/2003 00:00:00
KING, P. J., SWIFT, M. R., BURTALLY, N., BENNETT, M. and MELIA, C. D., 2003. PARTICLE PROCESSING New vibration driven processing technology European Pharmaceutical Review. VOL 8(PART 2), 58-63
COPE, S.J., HIBBERD, S., WHETSTONE, J., MACRAE, R.J. and MELIA, C.D., 2002. Measurement and mapping of pH in hydrating pharmaceutical pellets using confocal laser scanning microscopy Pharmaceutical Research. VOL 19(NUMBER 10), 1554-1563 KAUR, M., JUMEL, K., HARDIE, K. R., HARDMAN, A., MEADOWS, J. and MELIA, C. D., 2002. Determining the molar mass of a plasma substitute succinylated gelatin by size exclusion chromatography-multi-angle laser light scattering, sedimentation equilibrium and conventional size exclusion chromatography Journal of Chromatography A. VOL 957(NUMBER 2), 139-148 KAUR, M., HARDMAN, A., MELIA, C. D., JUMEL, K. and HIGGINBOTTOM, S., 2002. Improved SDS-PAGE Molecular Weight Determination of a Succinylated Limed Ossein Gelatin International Journal of Polymer Analysis and Characterization. VOL 7(PART 3), 195-209 MARSHALL, P., SNAAR, J.E., NG, Y.L., BOWTELL, R.W., HAMPSON, F.C., DETTMAR, P.W. and MELIA, C.D., 2001. A novel application of NMR microscopy: measurement of water diffusion inside bioadhesive bonds Magnetic Resonance Imaging. 19(3-4), 487-488 EHTEZAZI, T, WASHINGTON, C and MELIA, CD, 2000. First Order Release Rate From Porous Pla Microspheres With Limited Exit Holes On The Exterior Surface Journal Of Controlled Release. 66(1), 27-38
EHTEZAZI, T., WASHINGTON, C. and MELIA, C. D., 1999. Determination of the internal morphology of poly (D,L-lactide) microspheres using stereological methods Journal of Controlled Release. VOL 57(ISSUE 3), 301-314 NARASIMHAN, B, SNAAR, JEM, BOWTELL, RW, MORGAN, S, MELIA, CD and PEPPAS, NA, 1999. Magnetic Resonance Imaging Analysis Of Molecular Mobility During Dissolution Of Poly(Vinyl Alcohol) In Water Macromolecules. 32(3), 704-710
EHTEZAZI, T, WASHINGTON, C and MELIA, CD, 1999. Determination Of The Internal Morphology Of Poly (D,L-Lactide) Microspheres Using Stereological Methods Journal Of Controlled Release. 57(3), 301-314
BALDWIN, PM, ADLER, J, DAVIES, MC and MELIA, CD, 1998. High Resolution Imaging Of Starch Granule Surfaces By Atomic Force Microscopy Journal Of Cereal Science. 27(3), 255-265
MELIA, CD, RAJABI-SIAHBOOMI, AR and BOWTELL, RW, 1998. Magnetic Resonance Imaging Of Controlled Release Pharmaceutical Dosage Forms
BALDWIN, P.M., DAVIES, M.C. and MELIA, C.D., 1997. Starch granule surface imaging using low-voltage scanning electron microscopy and atomic force microscopy International Journal of Biological Macromolecules. 21(1-2), 103-107 KHAN, M.A., GEVARET, A., MELIA, C.D., DAVIS, S.S., MICHALSKI, L.A. and SCHACT, E.H., 1997. Novel polymers for coating of oral dosage forms to achieve colon-specific drug delivery Pharmaceutical Research. 14, S657-S658 SNAAR, J.E., BOWTELL, R.W., MELIA, C.D., PEPPAS, N.A. and NARASIMHAN, B., 1997. MRI analysis of soluble drug delivery carriers International Symposium on Controlled Release of Bioactive Materials. Proceedings book. 24, 171-172
MELIA, C D, MARSHALL, P, STARK, P, CUNNINGHAM, S, KINAHAN, A and DEVANE, J, 1997. Investigating in vitro drug release mechanisms inside dosage forms. Monitoring liquid ingress in HPMC hydrophilic matrices using confocal microscopy. Advances in Experimental Medicine and Biology. 423, 129-35
BALDWIN, PM, DAVIES, MC and MELIA, CD, 1997. Starch Granule Surface Imaging Using Low-Voltage Scanning Electron Microscopy And Atomic Force Microscopy
BALDWIN, PM, MELIA, CD and DAVIES, MC, 1997. The Surface Chemistry Of Starch Granules Studied By Time-Of-Flight Secondary Ion Mass Spectrometry Journal Of Cereal Science. 26(3), 329-346
MELIA, CD, MARSHALL, P, STARK, P, CUNNINGHAM, S, KINAHAN, A and DEVANE, J, 1997. Investigating In Vitro Drug Release Mechanisms Inside Dosage Forms - Monitoring Liquid Ingress In Hpmc Hydrophilic Matrices Using Confocal Microscopy
BALDWIN, PM, FRAZIER, RA, ADLER, J, GLASBEY, TO, KEANE, MP, ROBERTS, CJ, TENDLER, SJB, DAVIES, MC and MELIA, CD, 1996. Surface Imaging Of Thermally Sensitive Particulate And Fibrous Materials With The Atomic Force Microscope: A Novel Sample Preparation Method Journal Of Microscopy-Oxford. 184, 75-80
CUTTS, LS, HIBBERD, S, ADLER, J, DAVIES, MC and MELIA, CD, 1996. Characterising Drug Release Processes Within Controlled Release Dosage Forms Using The Confocal Laser Scanning Microscope Journal Of Controlled Release. 42(2), 115-124
SMITH, JC, DAVIES, MC, MELIA, CD, DENYER, SP and DERRICK, MR, 1996. Uptake Of Drugs By Catheters: The Influence Of The Drug Molecule On Sorption By Polyurethane Catheters Biomaterials. 17(15), 1469-1472
RAJABISIAHBOOMI, AR, BOWTELL, RW, MANSFIELD, P, DAVIES, MC and MELIA, CD, 1996. Structure And Behavior In Hydrophilic Matrix Sustained Release Dosage Forms .4. Studies Of Water Mobility And Diffusion Coefficients In The Gel Layer Of Hpmc Tablets Using Nmr Imaging Pharmaceutical Research. 13(3), 376-380
ADLER, J, BALDWIN, PM and MELIA, CD, 1995. Starch Damage .2. Types Of Damage In Ball-Milled Potato Starch, Upon Hydration Observed By Confocal Microscopy Starch-Starke. 47(7), 252-256
BALDWIN, PM, DAVIES, MC and MELIA, CD, 1995. Starch Damage .1. Characterization Of Granule Damage In Ball-Milled Potato Starch Study By Sem Starch-Starke. 47(7), 247-251
CUTTS, LS, ROBERTS, PA, ADLER, J, DAVIES, MC and MELIA, CD, 1995. Determination Of Localized Diffusion-Coefficients In Gels Using Confocal Scanning Laser Microscopy Journal Of Microscopy-Oxford. 180, 131-139
HODSDON, AC, MITCHELL, JR, DAVIES, MC and MELIA, CD, 1995. Structure And Behavior In Hydrophilic Matrix Sustained-Release Dosage Forms .3. The Influence Of Ph On The Sustained-Release Performance And Internal Gel Structure Of Sodium Alginate Matrices Journal Of Controlled Release. 33(1), 143-152
BALDWIN, PM, ADLER, J, DAVIES, MC and MELIA, CD, 1994. Holes In Starch Granules - Confocal, Sem And Light-Microscopy Studies Of Starch Granule Structure Starch-Starke. 46(9), 341-346
RAJABISIAHBOOMI, AR, BOWTELL, RW, MANSFIELD, P, HENDERSON, A, DAVIES, MC and MELIA, CD, 1994. Structure And Behavior In Hydrophilic Matrix Sustained-Release Dosage Forms .2. Nmr-Imaging Studies Of Dimensional Changes In The Gel Layer And Core Of Hpmc Tablets Undergoing Hydration Journal Of Controlled Release. 31(2), 121-128
1994. Nmr Microscopy Of Hydrating Hydrophilic Matrix Pharmaceutical Tablets
WATTS, PJ, WILSON, CG, DAVIES, MC and MELIA, CD, 1994. Radiolabeling Of Polymer Microspheres For Scintigraphic Investigations By Neutron-Activation .4. A Pharmacoscintigraphy Study Of Colon-Targeted Eudragit Rs-Sulfapyridine Microspheres In Human Volunteers International Journal Of Pharmaceutics. 102(1-3), 101-108
BOWTELL, R, SHARP, JC, PETERS, A, MANSFIELD, P, RAJABISIAHBOOMI, AR, DAVIES, MC and MELIA, CD, 1994. Nmr Microscopy Of Hydrating Hydrophilic Matrix Pharmaceutical Tablets Journal of Magnetic Resonance Imaging. 12, 361-364
TUDOR, AM, CHURCH, SJ, HENDRA, PJ, DAVIES, MC and MELIA, CD, 1993. The Qualitative And Quantitative-Analysis Of Chlorpropamide Polymorphic Mixtures By Near-Infrared Fourier-Transform Raman-Spectroscopy Pharmaceutical Research. 10(12), 1772-1776
MELIA, CD, RAJABISIAHBOOMI, AR, HODSDON, AC, ADLER, J and MITCHELL, JR, 1993. Structure And Behavior Of Hydrophilic Matrix Sustained-Release Dosage Forms .1. The Origin And Mechanism Of Formation Of Gas-Bubbles In The Hydrated Surface-Layer
WATTS, PJ, WILSON, CG, DAVIES, MC and MELIA, CD, 1993. Radiolabeling Of Polymer Microspheres For Scintigraphic Investigations By Neutron-Activation .2. Effects Of Irradiation On The Properties Of Eudragit Rs-Sulfasalazine Microspheres International Journal Of Pharmaceutics. 98(1-3), 63-73
WATTS, PJ, WILSON, CG, DAVIES, MC and MELIA, CD, 1993. Radiolabeling Of Polymer Microspheres For Scintigraphic Investigations By Neutron-Activation .3. Changes In The Physical-Properties Of Eudragit Rs-Sulfapyridine Microspheres From Incorporating Samarium Oxide International Journal Of Pharmaceutics. 98(1-3), 75-82
BARROW, L, STEED, KP, SPILLER, RC, MASKELL, NA, BROWN, JK, WATTS, PJ, MELIA, CD, DAVIES, MC and WILSON, CG, 1993. Quantitative, Noninvasive Assessment Of Antidiarrheal Actions Of Codeine Using An Experimental-Model Of Diarrhea In Man Digestive Diseases And Sciences. 38(6), 996-1003
TUDOR, AM, MELIA, CD, DAVIES, MC, ANDERSON, D, HASTINGS, G, MORREY, S, DOMINGOSSANDOS, J and BARBOSA, M, 1993. The Analysis Of Biomedical Hydroxyapatite Powders And Hydroxyapatite Coatings On Metallic Medical Implants By Near-Ir Fourier-Transform Raman-Spectroscopy Spectrochimica Acta Part A-Molecular And Biomolecular Spectroscopy. 49(5-6), 675-680
TUDOR, AM, MELIA, CD, DAVIES, MC, CHURCH, SJ and HELLER, J, 1993. The Analysis Of Biomedical Poly(Ortho Esters) By Near-Ir Fourier-Transform Raman-Spectroscopy Spectrochimica Acta Part A-Molecular And Biomolecular Spectroscopy. 49(5-6), 759-767
WREN, AE, MELIA, CD, GARNER, ST and DENYER, SP, 1993. Decontamination Methods For Cytotoxic Drugs .1. Use Of A Bioluminescent Technique To Monitor The Inactivation Of Methotrexate With Chlorine-Based Agents Journal Of Clinical Pharmacy And Therapeutics. 18(2), 133-137
WATTS, PJ, BARROW, L, STEED, KP, WILSON, CG, SPILLER, RC, MELIA, CD and DAVIES, MC, 1992. The Transit Rate Of Different-Sized Model Dosage Forms Through The Human Colon And The Effects Of A Lactulose-Induced Catharsis International Journal Of Pharmaceutics. 87(1-3), 215-221
BARROW, L, STEED, KP, SPILLER, RC, WATTS, PJ, MELIA, CD, DAVIES, MC and WILSON, CG, 1992. Scintigraphic Demonstration Of Lactulose-Induced Accelerated Proximal Colon Transit Gastroenterology. 103(4), 1167-1173
MANNION, RO, MELIA, CD, LAUNAY, B, CUVELIER, G, HILL, SE, HARDING, SE and MITCHELL, JR, 1992. Xanthan Locust Bean Gum Interactions At Room-Temperature Carbohydrate Polymers. 19(2), 91-97
BINNS, JS, CRAIG, DQM, HILL, RM, DAVIES, MC, MELIA, CD and NEWTON, JM, 1992. Dielectric Characterization Of Sodium Alginate Gels Journal Of Materials Chemistry. 2(5), 545-549
MELIA, CD, 1991. Hydrophilic Matrix Sustained-Release Systems Based On Polysaccharide Carriers
WATTS, PJ, ATKIN, BP, WILSON, CG, DAVIES, MC and MELIA, CD, 1991. Radiolabeling Of Polymer Microspheres For Scintigraphic Investigations By Neutron-Activation .1. Incorporation Of Samarium Oxide And Its Effects On The Properties Of Eudragit Rs - Sulfasalazine Microspheres International Journal Of Pharmaceutics. 76(1-2), 55-59
TUDOR, AM, MELIA, CD, DAVIES, MC, HENDRA, PJ, CHURCH, S, DOMB, AJ and LANGER, R, 1991. The Application Of Fourier-Transform Raman-Spectroscopy To The Analysis Of Poly(Anhydride) Homo-Polymers And Copolymers Spectrochimica Acta Part A-Molecular And Biomolecular Spectroscopy. 47(9-10), 1335-1343
TUDOR, AM, DAVIES, MC, MELIA, CD, LEE, DC, MITCHELL, RC, HENDRA, PJ and CHURCH, SJ, 1991. The Applications Of Near-Infrared Fourier-Transform Raman-Spectroscopy To The Analysis Of Polymorphic Forms Of Cimetidine Spectrochimica Acta Part A-Molecular And Biomolecular Spectroscopy. 47(9-10), 1389-1393
WATTS, PJ, TUDOR, A, CHURCH, SJ, HENDRA, PJ, TURNER, P, MELIA, CD and DAVIES, MC, 1991. Fourier Transform-Raman Spectroscopy For The Qualitative And Quantitative Characterization Of Sulfasalazine-Containing Polymeric Microspheres Pharmaceutical Research. 8(10), 1323-1328
WATTS, PJ, DAVIES, MC and MELIA, CD, 1991. Encapsulation Of 5-Aminosalicylic Acid Into Eudragit Rs Microspheres And Modulation Of Their Release Characteristics By Use Of Surfactants Journal Of Controlled Release. 16(3), 311-318