Ishwinder Kaur

Contact

• workRoom C30 Boots Science Building
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 8466241
• ishwinder.kaur@nottingham.ac.uk

Biography

• B.Pharm - Drug research and development, Panjabi University, Patiala, India. Graduated as one of the top three students with First Class.
• M.Pharm - University Institute of Pharmaceutical Sciences (UIPS), Panjab University, Chandigarh, India. Secured one of only five positions through a highly competitive entrance exam 'All India Graduate Aptitude Test in Engineering' with 91% percentile. Thesis work entitled "Development and evaluation of an Antioxidant Formulation as an Antiphotoageing agent".
• PhD - (Molecular and Cellular Sciences and Drug delivery) School of Pharmacy, University of Nottingham. Thesis work entitled "Nuclear translocation and Transferrin-Transferrin receptor interaction of IPSE/α-1, a secretory glycoprotein from Schistosoma mansoni" carried under the supervision of Dr Franco Falcone and Dr Snow Stolnik-Trenkic.
• 2009 - Postdoctoral Research Fellow, Laboratory of Biophysics and Surface analysis (LBSA) and Medicinal Chemistry and Structural Biology (MCSB), School of Pharmacy, University of Nottingham.

Research Summary

To work in a team of multidisciplinary scientists to develop and apply new methodologies to study protein unfolding; specifically in relation to the blood clotting von Willebrand's disease.… read more

Current Research

To work in a team of multidisciplinary scientists to develop and apply new methodologies to study protein unfolding; specifically in relation to the blood clotting von Willebrand's disease. Biomembrane force probe (BFP) and Molecular force probe (MFP)/ Force robot will be used to study force-induced protein unfolding. Different protein constructs with von Willebrand factor domains will be designed, produced and studied for the effect of neighbouring domains and mutations. This will also involve immobilization strategies and experimental procedures to facilitate new force-induced protein unfolding studies.