Seb Spain

Contact

• workRoom C30 Boots Science Building
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 846 6241
• sebastian.spain@nottingham.ac.uk
• http://www.nottingham.ac.uk/~pazsgs

Research Summary

Glycopolymers

Multivalency

Drug-delivery

Biomaterials

Selected Publications

• SPAIN, SEBASTIAN G, ALBERTIN, LUCA and CAMERON, NEIL R, 2006. Facile in situ preparation of biologically active multivalent glyconanoparticles. Chemical Communications. 4198-200
• SPAIN, S. G. and CAMERON, N. R., 2011. A spoonful of sugar: the application of glycopolymers in therapeutics Polymer Chemistry. 2, 60-68 (In Press.)
• GIBSON, MATTHEW I, BARKER, CARL A, SPAIN, SEBASTIAN G, ALBERTIN, LUCA and CAMERON, NEIL R, 2009. Inhibition of ice crystal growth by synthetic glycopolymers: implications for the rational design of antifreeze glycoprotein mimics. Biomacromolecules. 10(2), 328-33
• SPAIN, S. G., GIBSON, M. I. and CAMERON, N. R., 2007. Recent advances in the synthesis of well-defined glycopolymers Journal of Polymer Science Part A: Polymer Chemistry. 45(11), 2059-2072

• View all publications

• SPAIN, S. G. and CAMERON, N. R., 2011. A spoonful of sugar: the application of glycopolymers in therapeutics Polymer Chemistry. 2, 60-68 (In Press.)
• SEBASTIAN G. SPAIN* and NEIL R. CAMERON, 2011. The binding of polyvalent galactosides to the lectin Ricinus communis agglutinin 120 (RCA120): an ITC and SPR study Polymer Chemistry. 2, 1552-1560 (In Press.)
• SAMER R. ABULATEEFAH, SEBASTIAN G. SPAIN, JONATHAN W. AYLOTT, WENG CHAN, MARTIN C. GARNETT and CAMERON ALEXANDER, 2011. Thermoresponsive colloids in cancer therapy Macromolecular Bioscience.
• SEBASTIAN G. SPAIN, GÖKÇEN YAŞAYAN, MAHMOOD SOLIMAN, FELICITY HEATH, ARAM O. SAEED and CAMERON ALEXANDER, 2011. Nanoparticles for Nucleic Acid Delivery. In: PAUL DUCHEYNE, KEVIN E. HEALY, DIETMER W. HUTMACHER, DAVID W. GRAINGER and C. JAMES KIRKPATRICK, eds., Comprehensive Biomaterials 4. Elsevier. 389-410
• GIBSON, MATTHEW I, BARKER, CARL A, SPAIN, SEBASTIAN G, ALBERTIN, LUCA and CAMERON, NEIL R, 2009. Inhibition of ice crystal growth by synthetic glycopolymers: implications for the rational design of antifreeze glycoprotein mimics. Biomacromolecules. 10(2), 328-33
• CAMERON, NEIL R, SPAIN, SEBASTIAN G, KINGHAM, JAMES A, WECK, STEFAN, ALBERTIN, LUCA, BARKER, CARL A, BATTAGLIA, GIUSEPPE, SMART, THOMAS and BLANAZS, ADAM, 2008. Synthesis of well-defined glycopolymers and some studies of their aqueous solution behaviour. Faraday Discussions. 139, 359-68; discussion 399-417, 419-20
• SPAIN, S. G., GIBSON, M. I. and CAMERON, N. R., 2007. Recent advances in the synthesis of well-defined glycopolymers Journal of Polymer Science Part A: Polymer Chemistry. 45(11), 2059-2072
• SPAIN, SEBASTIAN G, ALBERTIN, LUCA and CAMERON, NEIL R, 2006. Facile in situ preparation of biologically active multivalent glyconanoparticles. Chemical Communications. 4198-200