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Jo Chalmers

Research Fellow, Faculty of Medicine & Health Sciences

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Biography

Following a degree and a PhD in Biochemistry from the University of Sheffield, Joanne spent five years in clinical research in the pharmaceutical industry. She joined the Centre of Evidence Based Dermatology in 2003, and since then has been involved in the design and implementation of several studies including a study of cost-effectiveness of treatments for cutaneous warts, an RCT to determine whether prophylactic antibiotics can prevent cellulitis, an RCT to compare doxycycline and prednisolone for bullous pemphigoid, a proof of principle trial to establish whether imiquimod is suitable for treating lentigo maligna and a study of antibiotics for wound healing in epidermolysis bullosa. Joanne is currently working on the eczema prevention workstream of the SPRUSD programme grant, undertaking an RCT to investigate whether regular emollient use from birth can prevent the onset of eczema in high risk babies and a systematic review of eczema prevention strategies.

Research Summary

The Barrier Enhancement for Eczema Prevention (BEEP) research study is looking at whether emollients used from birth can prevent or delay the onset of eczema in high risk babies. It is being run as… read more

Selected Publications

  • SIMPSON EL, KECK LE, CHALMERS JR and WILLIAMS HC, 2012. How Should An Incident Case Of Atopic Dermatitis Be Defined? A Systematic Review Of Primary Prevention Studies. The Journal Of Allergy And Clinical Immunology. (In Press.)
  • THOMAS, KIM S, KOLLER, KARIN, FOSTER, KATHARINE, PERDUE, JO, CHARLESWORTH, LISA and CHALMERS, JOANNE R, 2011. The UK Clinical Research Network - has it been a success for dermatology clinical trials? Trials. 12(1), 153
  • CHALMERS,J., THOMAS,K., DYAS,J.V., AVERY,A.J. and WILLIAMS,H.C., 2004. Oral Presentation. Attitudes towards current treatment for cutaneous warts- a qualitative study. Abstract: The British Epidemo-Epidemiology Society (BEES) Annual Meeting March 4th 2004 British Journal of Dermatology. 153(2), 474
  • UK DERMATOLOGY CLINICAL TRIALS NETWORK'S PATCH STUDY GROUP, 2007. Prophylactic Antibiotics for the Prevention of Cellulitis Journal of Lymphoedema. 2(1), 34-37

Current Research

The Barrier Enhancement for Eczema Prevention (BEEP) research study is looking at whether emollients used from birth can prevent or delay the onset of eczema in high risk babies. It is being run as part of an NIHR programme grant for applied research awarded to Professor Hywel Williams in 2008. The feasibility study started in early 2010 and there are four recruiting centres in the East Midlands region. This pilot study will show whether parents find it acceptable to use the barrier enhancement intervention (emollients) and whether it is feasible to run a large clinical trial to determine whether barrier enhancement is effective in preventing eczema. This subsequent trial will be rolled out to other areas of the UK and other countries.

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