Austin Acheson

Contact

• workRoom W/E1373 West Block
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work0115 82 31147
• fax0115 82 31160
• austin.acheson@nottingham.ac.uk

Research Summary

Interests

• Chronic anal fissure

• Anal sphincter Pharmacology

• Intravenous iron therapy in IDA

• Laparoscopic Colorectal Surgery

Techniques

• In vitro models for sphincter pharmacology

• clinical studies

Projects

• Intravenous iron for colorectal cancer/oesophagogastric cancer

• Contractile and radioligand studies in the anal sphincter

• Methoxamine and faecal incontinence

• The effect of statins on the mortality associated with sepsis and elective colorectal surgery

• Consent in emergency laparotomy

Recent Publications

• ACHESON AG, BROOKES MJ and SPAHN D, 2012. Effects of allogeneic red blood cell transfusions on clinical outcomes in patients undergoing colorectal cancer surgery - Systematic review and meta-analysis Annals of Surgery. (In Press.)
• WYLES SM, MISKOVIC D, NI Z, ACHESON AG, MAXWELL-ARMSTRONG C, LONGMAN R, CECIL T, COLEMAN MG, HORGAN AF and HANNA GB, 2011. Analysis Of Laboratory-Based Laparoscopic Colorectal Surgery Workshops Within The English National Training Programme. Surgical Endoscopy. 25(5), 1559-66
• LLOYD GM, MAXWELL-ARMSTRONG C and ACHESON AG, 2011. Fresh Frozen Cadavers: An Under-Utilized Resource In Laparoscopic Colorectal Training In The United Kingdom. Colorectal Disease : The Official Journal Of The Association Of Coloproctology Of Great Britain And Ireland. 13(9), e303-4
• CONAGHAN PJ, MAXWELL-ARMSTRONG CA, GARRIOCH MV, HONG L and ACHESON AG, 2011. Leaving A Mark: The Frequency And Accuracy Of Tattooing Prior To Laparoscopic Colorectal Surgery. Colorectal Disease : The Official Journal Of The Association Of Coloproctology Of Great Britain And Ireland. 13(10), 1184-7

• View all publications

• ACHESON AG, BROOKES MJ and SPAHN D, 2012. Effects of allogeneic red blood cell transfusions on clinical outcomes in patients undergoing colorectal cancer surgery - Systematic review and meta-analysis Annals of Surgery. (In Press.)
• WYLES SM, MISKOVIC D, NI Z, ACHESON AG, MAXWELL-ARMSTRONG C, LONGMAN R, CECIL T, COLEMAN MG, HORGAN AF and HANNA GB, 2011. Analysis Of Laboratory-Based Laparoscopic Colorectal Surgery Workshops Within The English National Training Programme. Surgical Endoscopy. 25(5), 1559-66
• LLOYD GM, MAXWELL-ARMSTRONG C and ACHESON AG, 2011. Fresh Frozen Cadavers: An Under-Utilized Resource In Laparoscopic Colorectal Training In The United Kingdom. Colorectal Disease : The Official Journal Of The Association Of Coloproctology Of Great Britain And Ireland. 13(9), e303-4
• CONAGHAN PJ, MAXWELL-ARMSTRONG CA, GARRIOCH MV, HONG L and ACHESON AG, 2011. Leaving A Mark: The Frequency And Accuracy Of Tattooing Prior To Laparoscopic Colorectal Surgery. Colorectal Disease : The Official Journal Of The Association Of Coloproctology Of Great Britain And Ireland. 13(10), 1184-7
• RAYMENT SJ, EAMES T, SIMPSON JA, DASHWOOD MR, HENRY Y, GRUSS H, ACHESON AG, SCHOLEFIELD JH, WILSON VG, 2010. Investigation of the distribution and function of alpha adrenoceptors in the sheep isolated internal anal sphincter British Journal of Pharmacology. 160(7), 1727-40
• CONAGHAN P, MAXWELL-ARMSTRONG C, BEDFORTH N, GORNALL C, BAXENDALE B, HONG L, CARTY H and ACHESON AG, 2010. Efficacy Of Transversus Abdominis Plane Blocks In Laparoscopic Colorectal Resections. Surgical Endoscopy. 24(10), 2480-4
• SIMPSON JAD, TSELEPIS C, IQBAL T, ACHESON AG and BROOKES MJ, 2010. Letter 2: Randomized Clinical Trial Of Preoperative Intravenous Iron Sucrose To Reduce Blood Transfusion In Anaemic Patients After Colorectal Cancer Surgery (Br J Surg 2009; 96: 1122-1128). The British Journal Of Surgery. 97(2), 298-9; author reply 299
• MORRIS CR, GORNALL C, CONAGHAN P, MAXWELL-ARMSTRONG C and ACHESON A, 2010. Response To Levy Et Al.: Postoperative Analgesia Following Laparoscopic Colorectal Surgery. Colorectal Disease : The Official Journal Of The Association Of Coloproctology Of Great Britain And Ireland. 12(5), 494-5
• KHOO, ERIC Y H, RISLEY, JAMES, ZAITOUN, ABED M, EL-SHEIKH, MOHAMED, PAISEY, RICHARD B, ACHESON, AUSTIN G and MANSELL, PETER, 2009. Alström syndrome and cecal volvulus in 2 siblings. The American journal of the medical sciences. 337(5), 383-5
• ACHESON A, RAYMENT S, EAMES T, MUNDEY M, NISAR P, SCHOLEFIELD J and WILSON VG, 2009. Investigation of the role of adrenergic and non-nitrergic, non-adrenergic neurotransmission in the sheep isolated internal anal sphincter. Neurogastroenterology and Motility. 21(3), 335-345
• COLLIN JE, ATWAL GS, DUNN WK and ACHESON AG, 2009. Laparoscopic-Assisted Resection Of A Giant Colonic Diverticulum: A Case Report. Journal Of Medical Case Reports. 3, 7075
• KANG PS, HORGAN AF and ACHESON AG, 2009. Laparoscopic Surgery Training. Try Fresh Frozen Cadavers. Bmj (Clinical Research Ed.). 338, b2426
• CONAGHAN PJ and ACHESON AG, 2009. Don't Overlook Minimally Invasive Colorectal Cancer Surgery. European Journal Of Vascular And Endovascular Surgery : The Official Journal Of The European Society For Vascular Surgery. 38(1), 137; author reply 137-8
• FITZGERALD JEF, FITZGERALD LA, ANDERSON FE and ACHESON AG, 2009. The Changing Nature Of Rectus Sheath Haematoma: Case Series And Literature Review. International Journal Of Surgery (London, England). 7(2), 150-4
• YEUNG JMC, MAXWELL-ARMSTRONG C and ACHESON AG, 2009. Colonic Tattooing In Laparoscopic Surgery - Making The Mark? Colorectal Disease : The Official Journal Of The Association Of Coloproctology Of Great Britain And Ireland. 11(5), 527-30
• ACHESON AG, SCHOLEFIELD JH, 2008. Management of haemorrhoids BMJ. 336(7640), 380-3
• SIMPSON J, HUMES DJ, O'ROURKE EJ, JAMES PD and ACHESON AG, 2008. Rigler On The Roof. Rigler's Sign. Gut. 57(6), 798, 836
• FITZGERALD JEF, SIMPSON JAD and ACHESON AG, 2008. The Use Of Intravenous Iron In Patients With Cancer Related Anaemia: Don't Overlook Iron Deficiency Anaemia In Colorectal Cancer. British Journal Of Haematology. 143(5), 754; author reply 755
• SMITH JK, ACHESON AG, SIMPSON JAD, STEWART J, BECKINGHAM IJ, GORNALL CB, WILLIAMS JP, ROBINSON MH and MAXWELL-ARMSTRONG CA, 2008. From Small Acorns--Developing A Laparoscopic Colorectal Surgical Service. Annals Of The Royal College Of Surgeons Of England. 90(7), 606-11
• ACHESON AG and SCHOLEFIELD JH, 2008. Survival From Cancers Of The Colon And Rectum In England And Wales Up To 2001. British Journal Of Cancer. 99 Suppl 1, S33-4
• FITZGERALD JEF, NIKKAR-ESFAHANI A, JAMJOOM AAB, SHAH KK and ACHESON AG, 2008. Aspects Of Summary Care Records: Let's Put Worry About Computer Security Into Perspective. Bmj (Clinical Research Ed.). 336(7659), 1452-3
• FITZGERALD JEF, TANG SW, LAKE EJ, RICHARDS T and ACHESON AG, 2008. Small Bowel Evisceration: A Rare Complication Of Laparoscopic Ileostomy. Colorectal Disease : The Official Journal Of The Association Of Coloproctology Of Great Britain And Ireland. 10(4), 407-8
• NISAR PJ, GRUSS H, BUSH D, ACHESON AG and SCHOLEFIELD JH, 2007. Intra-Anal Application Of L-Erythro Methoxamine Gel Increases Anal Resting Pressure In Patients With Incontinence. The British Journal Of Surgery. 94(9), 1155-61
• NISAR, P.J., GRUSS, H.J., BUSH, D., BARRAS, N., ACHESON, A.G. and SCHOLEFIELD, J.H., 2005. Intra-anal and rectal application of L-erythro methoxamine gel increases anal resting pressure in healthy volunteers British Journal of Surgery. 92(12), 1539-1545
• JONAS-OBICHERE, M., SCHOLEFIELD, J.H., ACHESON, A., MUNDEY, M., TYLER, H. and WILSON, V.G., 2005. Comparison of the effects of nitric oxide donors and calcium channel blockers on the intrinsic myogenic tone of sheep isolated internal anal sphincter British Journal of Surgery. 92(10), 1263-1269
• ACHESON, A. G. and SCHOLEFIELD, J. H., 2005. Anal fissure: the changing management of a surgical condition Langenbeck's Archives of Surgery. VOL 390(NUMB 1), 1-7
• ACHESON, A.G. and SCHOLEFIELD, J.H., 2005. Pharmacological advancements in the treatment of chronic anal fissure Expert Opinion on Pharmacotherapy. 6(14), 2475-2481
• GRIFFIN, N., ACHESON, A.G., TUNG, P., SHEARD, C., GLAZEBROOK, C. and SCHOLEFIELD, J.H., 2004. Quality of life in patients with chronic anal fissure. Colorectal Disease. 6(1), 39-44
• NISAR, P.J., ACHESON, A.G., NEAL, K.R. and SCHOLEFIELD, J.H., 2004. Stapled hemorrhoidopexy compared with conventional hemorrhoidectomy: systematic review of randomized, controlled trials. Diseases of the Colon and Rectum. 47(11), 1837-1845
• NISAR PJ, ACHESON AG, NEAL KR and SCHOLEFIELD JH, 2004. Stapled Hemorrhoidopexy Compared With Conventional Hemorrhoidectomy: Systematic Review Of Randomized, Controlled Trials. Diseases Of The Colon And Rectum. 47(11), 1837-45
• GRIFFIN N, ACHESON AG, TUNG P, SHEARD C, GLAZEBROOK C and SCHOLEFIELD JH, 2004. Quality Of Life In Patients With Chronic Anal Fissure. Colorectal Disease : The Official Journal Of The Association Of Coloproctology Of Great Britain And Ireland. 6(1), 39-44
• ACHESON, A. G., GRIFFIN, N., SCHOLEFIELD, J. H. and WILSON, V. G., 2003. l-Arginine-induced relaxation of the internal anal sphincter is not mediated by nitric oxide British Journal of Surgery. 90(9), 1155-1162
• ACHESON,A.G. and SCHOLEFIELD,J., 2003. Haemorrhoids Surgery. 21(7), 165-7
• ACHESON, A. G., COLLYER, J. and MCPHERSON, G. A., 2003. An unusual cause of persistent vomiting Postgraduate Medical Journal. VOL 79(MAR), 178
• ACHESON AG, COLLYER J and MCPHERSON GA, 2003. An Unusual Cause Of Persistent Vomiting. Postgraduate Medical Journal. 79(929), 178, 181-2
• GRIFFIN, N., ZIMMERMAN, D. D. E., BRIEL, J. W., GRUSS, H.-J., JONAS, M., ACHESON, A. G., NEAL, K., SCHOLEFIELD, J. H. and SCHOUTEN, W. R., 2002. Topical L-Arginine Gel Lowers Resting Anal Pressure: Possible Treatment for Anal Fissure Diseases of the Colon and Rectum. VOL 45(PART 10), 1332-1336
• GRIFFIN, N., ACHESON, A. G., JONAS, M. and SCHOLEFIELD, J. H., 2002. The role of topical diltiazem in the treatment of chronic anal fissures that have failed glyceryl trinitrate therapy Colorectal Disease. VOL 4(NUMB 6), 430-435
• ACHESON, A G, GRIFFIN, N and SCHOLEFIELD, J H, 2002. Randomized clinical trial assessing the side-effects of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure (Br J Surg 2002; 89: 413-17). British Journal of Surgery. 89(9), 1193; author reply 1193-4
• ACHESON,A.G. and SCHOLEFIELD,J., 2002. What is new in colorectal cancer? Surgery. 20(10), 244-8
• ACHESON, A.G. and SCHOLEFIELD, J., 2002. The role of botulinum toxin in gastrointestinal surgery.. In: Recent Advances in Surgery 25. Royal Society of Medicine Press Ltd, London. 57-70
• GRIFFIN N, ZIMMERMAN DDE, BRIEL JW, GRUSS H, JONAS M, ACHESON AG, NEAL K, SCHOLEFIELD JH and SCHOUTEN WR, 2002. Topical L-Arginine Gel Lowers Resting Anal Pressure: Possible Treatment For Anal Fissure. Diseases Of The Colon And Rectum. 45(10), 1332-6
• ACHESON, A G and SCHOLEFIELD, J H, 2001. Operative treatment of anal fissure. Annals of the Royal College of Surgeons of England. 83(6), 437-8
• ACHESON, A G, YOUSAF, M, GRIFFITHS, C L and TAYLOR, O M, 2000. Diagnostic dilemma of hyperamylasaemia in acute abdominal emergencies. The Ulster medical journal.. 69(1), 63-4
• ACHESON, A G, BROOKS, T M and TAYLOR, O M, 1999. Orbital haemorrhage as a complication of gastroscopy. Endoscopy. 31(6), 509
• ACHESON, A G, 1999. Can we ever be certain of the diagnosis of acute pancreatitis? Gut. 44(5), 765
• KENNEDY, P T, GILLESPIE, J S and ACHESON, A G, 1999. An unlucky break. British Journal of Radiology. 72(854), 219-20
• LEE, J, MCCALLION, K, ACHESON, A G and IRWIN, S T, 1999. A prospective randomised study comparing polyethylene glycol and sodium phosphate bowel cleansing solutions for colonoscopy. The Ulster medical journal.. 68(2), 68-72
• ACHESON, A G, GRAHAM, A N, WEIR, C and LEE, B, 1998. Prospective study on factors delaying surgery in ruptured abdominal aortic aneurysms. The Journal of the Royal College of Surgeons of Edinburgh. 43(3), 182-4
• ACHESON, A G, 1997. Do male medical students face prejudice? Lancet. 350(9082), 964
• ACHESON, A, MCILRATH, E and BARROS D'SA, A A, 1997. Pelvic lipoma causing venous obstruction syndrome. European Journal of Vascular and Endovascular Surgery. 14(2), 149-50
• DUNCAN TJ, LEE S, ACHESON AG and HAMMOND RH, 1. An Ovarian Stromal Tumor With Luteinized Cells: An Unusual Recurrence Of An Unusual Tumor. International Journal Of Gynecological Cancer : Official Journal Of The International Gynecological Cancer Society. 18(1), 172-5