SEBERT, S P, DELLSCHAFT, N S, CHAN, L L Y, STREET, H, HENRY, M, FRANCOIS, C, SHARMA, V, FAINBERG, H P, PATEL, N, RODA, J, KEISLER, D, BUDGE, H and SYMONDS, M E, 2011. Maternal nutrient restriction during late gestation and early postnatal growth in sheep differentially reset the control of energy metabolism in the gastric mucosa. Endocrinology. 152(7), 2816-26 SYMONDS, MICHAEL E, BUDGE, HELEN, PERKINS, ALAN C and LOMAX, MICHAEL A, 2011. Adipose tissue development - Impact of the early life environment. Progress in Biophysics and Molecular Biology. 106(1), 300-6 SEBERT, S., SHARKEY, D, BUDGE, H and SYMONDS, M.E., 2011. The early programming of metabolic health: is epigenetic setting the missing link? American Journal of Clinical Nutrition. 94(6), 1953S-1958S SYMONDS, M.E., SEBERT, S. and BUDGE, H., 2011. The obesity epidemic: from the environment to epigenetics - not simply a response to dietary manipulation in a thermoneutral environment Frontiers in Genetics. 2(24), 1-10
ATKINSON, M and BUDGE, H, 2011. Review Of The Nice Guidance On Neonatal Jaundice Archives Of Disease In Childhood-Education And Practice Edition. 96(4), 136-140 FAINBERG HP, BUDGE H and SYMONDS ME, 2011. Proceedings of the Nutrition Society The conflicting effects of maternal nutrient restriction and early-life obesity on renal health. 70(2), 268-275
HYATT, MA, GARDNER, DS, SEBERT, S, WILSON, V, DAVIDSON, N, NIGMATULLINA, Y, CHAN, LLY, BUDGE, H and SYMONDS, ME, 2011. Suboptimal Maternal Nutrition, During Early Fetal Liver Development, Promotes Lipid Accumulation In The Liver Of Obese Offspring Reproduction. 141(1), 119-126 SEBERT S, HYATT MA, CHAN LLY, YIALLOURIDES M, FAINBERG HP, PATEL N, SHARKEY D, STEPHENSON T, RHIND S, BELL RC, BUDGE H, GARDNER DS and SYMONDS ME, 2010. Reproduction Influence Of Prenatal Nutrition And Obesity On Tissue Specific Fat Mass And Obesity-Associated (FTO) Gene Expression. 139, 2583-2587
HYATT MA, KEISLER DH, BUDGE H and SYMONDS ME, 2010. Journal of Endocrinology Maternal parity and its effect on adipose tissue deposition and endocrine sensitivity in the postnatal sheep. 204(2), 173-9
SHARKEY, DON, FAINBERG, HERNAN P, WILSON, VICKY, HARVEY, EMMA, GARDNER, DAVID S, SYMONDS, MICHAEL E and BUDGE, HELEN, 2009. Impact of early onset obesity and hypertension on the unfolded protein response in renal tissues of juvenile sheep. Hypertension. 53(6), 925-31
SHARKEY, DON, SYMONDS, MICHAEL E and BUDGE, HELEN, 2009. Adipose tissue inflammation: developmental ontogeny and consequences of gestational nutrient restriction in offspring. Endocrinology. 150(8), 3913-20
SEBERT, S.P., HYATT, M.A., CHAN, L.L.Y., PATEL,N., BELL, R.C., KEISLER, T., STEPHENSON, T., BUDGE, H., SYMONDS, M.E. and GARDNER, D.S., 2009. Maternal Nutrient Restriction between Early and Midgestation and its Impact upon Appetite Regulation after Juvenile Obesity Endocrinology: Energy Balance-Obesity. 150(2), 634-641 SHARKEY, D., GARDNER, D.S., FAINBERG, H.P., SEBERT, S., BOS, P., WILSON, V., BELL, R., SYMONDS, M.E. and BUDGE, H., 2009. Maternal nutrient restriction during pregnancy differentially alters the unfolded protein response in adipose and renal tissue of obese juvenile offspring The FASEB Journal: Research Communication. 23, 1314-1324 SYMONDS, ME, SEBERT, SP, HYATT, MA and BUDGE, H, 2009. Nutritional Programming Of The Metabolic Syndrome Proceedings of the Nutrition Society. 68(2), 173-8 YIALLOURIDES M, SEBERT SP, WILSON V, SHARKEY D, RHIND SM, SYMONDS ME and BUDGE H, 2009. Reproduction The differential effects of the timing of maternal nutrient restriction in the ovine placenta on glucocorticoid sensitivity, uncoupling protein 2, peroxisome proliferator-activated receptor-gamma and cell proliferation. 138(3), 601-8
BUDGE H, SEBERT S, SHARKEY D and SYMONDS ME, 2009. Adipose tissue development, nutrition in early life and its impact on later obesity Proceedings of the Nutrition Society. 68(3), 321-6 HYATT, M A, BUTT, E A, BUDGE, H, STEPHENSON, T and SYMONDS, M E, 2008. Effects of maternal cold exposure and nutrient restriction on the ghrelin receptor, the GH-IGF axis, and metabolic regulation in the postnatal ovine liver. Reproduction (Cambridge, England). 135(5), 723-32
WILLIAMS, P.J., KURLAK, L.O., PERKINS, A.C., BUDGE, H., STEPHENSON, T., KEISLER, D., SYMONDS, M.E. and GARDNER, D.S., 2007. Hypertension and impaired renal function accompany juvenile obesity: the effect of prenatal diet Kidney International. 72(3), 279-289 HYATT, M.A., BUDGE, H., WALKER, D., STEPHENSON, T. and SYMONDS, M.E., 2007. Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep. Endocrinology. 148(10), 4754-4760 HYATT,M.A., GOPALAKRISHNAN,G.S., BISPHAM,J., GENTILI,S., MCMILLEN,I.C., RHIND,S.M., RAE,M.T., KYLE,C.E., BROOKS,A.N., JONES,C., BUDGE,H., WALKER,D., STEPHENSON,T. and SYMONDS,M.E, 2007. Maternal nutrient restriction in early pregnancy programs hepatic mRNA expression of growth-related genes and liver size in adult male sheep Journal of Endocrinology. 192(1), 87-97 HYATT, M.A., BUDGE, H., WALKER, D., STEPHENSON, T. and SYMONDS, M.E., 2007. Effects of maternal parity and late gestational nutrition on mRNA abundance for growth factors in the liver of postnatal sheep. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 292(5), R1934-R1942 BUDGE, H., STEPHENSON, T and SYMONDS, M.E., 2007. Maternal Nutrient Restriction is not equivalent to Maternal Biological Stress Current Drug Targets. 8, 888-893 SYMONDS,M.E., STEPHENSON,T.J.:GARDNER,D.S. and BUDGE,H, 2007. Long-term effects of nutritional programming of the embryo and fetus: mechanisms and critical windows Reproduction, Fertility and Development. 19, 53-63 (In Press.)
GNANALINGHAM, M.G., WILLIAMS, P., WILSON, V., BISPHAM, J., HYATT, M.A., PELLICANO, A., BUDGE, H., STEPHENSON, T. and SYMONDS, M.E., 2007. Nutritional manipulation between early to mid-gestation: effects on uncoupling protein-2, glucocorticoid sensistivity, IGF-1 receptor and cell proliferation but not apoptosis in the ovine placenta Reproduction. 134, 615-623 (In Press.)
YAKUBU, D.P., MOSTYN, A., HYATT, M.A., KURLAK, L.O., BUDGE, H., STEPHENSON, T. and SYMONDS, M.E., 2007. Ontegeny and nutritional programming of mitochondrial proteins in the ovine kidney, liver and lung Reproduction. 134, 823-830 YAKUBU, D.P., MOSTYN, A., WILSON, V., PEARCE, S., ALVES-GUERRA, M.C., PECQUEUR, C., MIROUX, B., BUDGE, H., STEPHENSON T. and SYMONDS, M.E., 2007. Different effects of maternal parity, cold exposure and nutrient restriction in late pregnancy on the abundance of mitochondrial proteins in the kidney, liver and lung of postnatal sheep Reproduction. 133, 1241-1252 SYMONDS, M., BUDGE, H., MOSTYN, A., STEPHENSON, T. and GARDNER, D., 2007. Maternal diet through pregnancy: the key to future good health of the next generation?. In: SARAH V WATKINS, ed., Nutrition Research Advances: Reducing diets: new research New York: Nova Science Publishers Inc. 223-240
SYMONDS, M. E., BUDGE, H., MOSTYN, A., STEPHENSON, T. and GARDNER, D. S., 2006. Nutritional Programming of Foetal Development: Endocrine Mediators and Long-Term Outcomes for Cardiovascular Health Current Nutrition and Food Science. VOL 2(NUMB 4), 389-398 BUTT, E., HYATT, M.A., BUDGE, H., SYMONDS, M.E. and STEPHENSON, T., 2006. Efffect of maternal cold exposure and nutrient restriction on insulin-like growth factor sensitivity in adipose tissue of newborn sheep Adipocytes. 2(3-4), 109-116 (In Press.)
PEARCE, S., BUDGE, H., MOSTYN, A., GENEVER, E., WEBB, R., INGLETON, P., WALKER, A.M., SYMONDS, M.E. and STEPHENSON, T., 2005. Prolactin, the prolactin receptor and uncoupling protein abundance and function in adipose tissue during development in young sheep Journal of Endocrinology. 184(2), 351-359 BISPHAM, J., GARDNER, D.S., GNANALINGHAM, M.G., STEPHENSON, T., SYMONDS, M.E. and BUDGE, H., 2005. Maternal nutritional programming of fetal adipose tissue development : differential effects on messenger ribonucleic acid abundance for uncoupling proteins and peroxisome proliferator-activated and prolactin receptors Endocrinology. 146(9), 3943-3949 BUDGE, H., GNANALINGHAM, M. G., GARDNER, D. S., MOSTYN, A., STEPHENSON, T. and SYMONDS, M. E., 2005. Maternal Nutritional Programming of Fetal Adipose Tissue Development: Long-Term Consequences for Later Obesity Birth Defects Research. VOL 75(NUMB 3), 193-199 PEARCE, S., BUDGE, H.J., MOSTYN, A., KORUR, N., WANG, J., INGLETON, P. and SYMONDS M.E. AND STEPHENSON, T., 2005. Differential effects of maternal cold exposure and nutrient restriction on prolactin receptor and uncoupling protein 1 abundance in adipose tissue during development in young sheep Adipocytes. 1(1), 57-64
MARLOW, N. and BUDGE, H., 2005. Prevalence, causes, and outcome at 2 years of age of newborn encephalopathy Archives of Disease in Childhood. Fetal and Neonatal Edition. 90(3), 193-194 BUDGE, H., EDWARDS, L.J., MCMILLEN, I.C., BRYCE, A., WARNES, K., PEARCE, S., STEPHENSON, T. and SYMONDS, M.E., 2004. Nutritional manipulation of fetal adipose tissue deposition and uncoupling protein 1 messenger RNA abundance in the sheep : differential effects of timing and duration Biology of Reproduction. 71(1), 359-365 BISPHAM, J., GOPALAKRISHNAN, G.S., DANDREA, J., WILSON, V., BUDGE, H., KEISLER, D.H., BROUGHTON PIPKIN, F., STEPHENSON, T. and SYMONDS, M.E., 2003. Maternal endocrine adaptation throughout pregnancy to nutritional manipulation : consequences for maternal plasma leptin and cortisol and the programming of fetal adipose tissue development Endocrinology. 144(8), 3575-3585 BUDGE, H., DANDREA, J., MOSTYN, A., EVENS, Y., WATKINS, R., SULLIVAN, C., INGLETON, P., STEPHENSON, T. and SYMONDS, M.E., 2003. Differential effects of fetal number and maternal nutrition in late gestation on prolactin receptor abundance and adipose tissue development in the neonatal lamb Pediatric Research. 53(2), 302-308 MOSTYN, A., PEARCE, S., BUDGE, H., ELMES, M., FORHEAD, A. J., FOWDEN, A. L., STEPHENSON, T. and SYMONDS, M. E., 2003. Influence of cortisol on adipose tissue development in the fetal sheep during late gestation Journal of Endocrinology. 176(1), 23-30 MÜHLHÄUSLER, B.S., ROBERTS, C.T., YUEN, B.S.J., MARROCCO, E., BUDGE, H., SYMONDS, M.E., MCFARLANE, J.R., KAUTER, K.G., STAGG, P., PEARSE, J.K. and MCMILLEN, I.C., 2003. Determinants of fetal leptin synthesis, fat mass, and circulating leptin concentrations in well-nourished ewes in late pregnancy Endocrinology. 144(11), 4947-4954 MOSTYN, A, WILSON, V, DANDREA, J, YAKUBU, D P, BUDGE, H, ALVES-GUERRA, M C, PECQUEUR, C, MIROUX, B, SYMONDS, M E and STEPHENSON, T, 2003. Ontogeny and nutritional manipulation of mitochondrial protein abundance in adipose tissue and the lungs of postnatal sheep. British Journal of Nutrition. 90(2), 323-8 SYMONDS, M.E., MOSTYN, A., PEARCE, S., BUDGE, H. and STEPHENSON, T., 2003. Endocrine and nutritional regulation of fetal adipose tissue development Journal of Endocrinology. 179(3), 293-9 BISPHAM, J., BUDGE, H., MOSTYN, A., DANDREA, J., CLARKE, L., KEISLER, D. H., SYMONDS, M. E. and STEPHENSON, T., 2002. Ambient temperature, maternal dexamethasone, and postnatal ontogeny of leptin in the neonatal lamb Pediatric Research. 52(1), 85-90 BUDGE, H., MOSTYN, A., WILSON, V., KHONG, A., WALKER, A. M., SYMONDS, M. E. and STEPHENSON, T., 2002. The effect of maternal prolactin infusion during pregnancy on fetal adipose tissue development Journal of Endocrinology. 174(3), 427-433 BUDGE, H., SEETHO, I.W., GOPALAKRISHNAN, G., DANDREA, J., WILSON, V., MOSTYN, A., WALKER, R.M., RAMSAY, M.M., SYMONDS, M.E. and STEPHENSON, T., 2002. Maternal nutritional programming of blood pressure responses and kidney development during juvenile life Archives of Disease in Childhood. 86(suppl 1), A23 BUDGE, H., WILSON, V., MOSTYN, A., DANDREA, J., DYER, L., ALVES-GUERRA, M.C., PECQUEUR, C., MIROUX, B., STEPHENSON, T. and SYMONDS, M.E., 2002. Maternal nutrient restriction in late gestation reprogrammes uncoupling protein 2 and voltage-dependent anion channel abundance in the lung during postnatal development Archives of Disease in Childhood. 86(suppl 1), A37 SYMONDS, M.E., BUDGE, H., EDWARDS, L., STEPHENSON, T. and MCMILLEN, I.C., 2002. Maternal nutrition, cortisol and programming of fetal development Journal of Perinatology. 4, 4
SYMONDS, M.E., BUDGE, H.J. and STEPHENSON, T.J., 2002. Physiological and nutritional aspects of the placenta. In: MORGAN, J.B. and DICKERSON, J.W.T., eds., Nutrition in early life Chichester: John Wiley & Sons. 91-121
WHORWOOD, C.B., FIRTH, K.M., BUDGE, H. and SYMONDS, M.E., 2001. Maternal undernutrition during early to midgestation programs tissue-specific alterations in the expression of the glucocorticoid receptor, 11ß-hydroxysteroid dehydrogenase isoforms, and type 1 angiotensin II receptor in neonatal sheep Endocrinology. 142(7), 2854-2864 DANDREA, J., WILSON, V., GOPALAKRISHNAN, G., HEASMAN, L., BUDGE, H., STEPHENSON, T. and SYMONDS, M. E., 2001. Maternal nutritional manipulation of placental growth and glucose transporter 1 (GLUT-1) abundance in sheep Reproduction. 122(5), 793-800 BUDGE, H., KEISLER, D., STEPHENSON, T. and SYMONDS, M., 2001. Influence of postnatal age on plasma leptin and adipose tissue deposition Archives of Disease in Childhood. 84(Suppl 1), A21 BIRD, J.A., MOSTYN, A., CLARKE, L., JUNIPER, D.T., BUDGE, H., STEPHENSON, T. and SYMONDS, M.E., 2001. Effect of postnatal age and a beta~3-adrenergic agonist (Zeneca D7114) administration on uncoupling protein-1 abundance in the lamb Experimental Physiology. 86(1), 65-70 BUDGE, H., MOSTYN, A., WILSON, V., WALKER, A. M., SYMONDS, M. E. and STEPHENSON, T., 2001. Effect of administration of prolactin throughout rat pregnancy on brown adipose tissue development Proceedings of the Nutrition Society. VOL 60(SPI/OCB), 194A
MOSTYN, A., PEARCE, S., BUDGE, H., KEISLER, D., MORRISON, C., WEBB, R., STEPHENSON, T. and SYMONDS, M., 2001. Effect of chronic leptin administration on plasma leptin, prolactin and UCP1 in neonatal lambs Biochemical Society Transactions. 29(1), A39
BUDGE, H.J. and STEPHENSON, T.J., 2001. The newborn. In: , ed., Turnbull's Obstetrics 3rd. Edinburgh: Churchill Livingstone. 681-700
BUDGE,H.J., 2001. Paediatric reference values. In: Pocket Paediatrics Churchill Livingstone, Edinburgh, UK. 413-420
BUDGE, H., BISPHAM, J., DANDREA, J., EVANS, E., HEASMAN, L., INGLETON, P.M., SULLIVAN, C., WILSON, V., STEPHENSON, T. and SYMONDS, M.E., 2000. Effect of maternal nutrition on brown adipose tissue and its prolactin receptor status in the fetal lamb Pediatric Research. 47(6), 781-786 BUDGE, H., DANDREA, J., INGLETON, P., STEPHENSON, T. and SYMONDS, M.E., 2000. Effect of fetal number on prolactin receptor abundance in perirenal adipose tissue of neonatal lambs Early Human Development. 58(1), 72 HEASMAN, L, BRAMELD, J, MOSTVN, A, BUDGE, H, DAWSON, J, BUTTERY, P, STEPHENSON, T and SYMONDS, M E, 2000. Maternal nutrient restriction during early to mid gestation alters the relationship between insulin-like growth factor I and bodyweight at term in fetal sheep. Reproduction, fertility, and development. 12(7-8), 345-50 BUDGE, H.J., HEASMAN, L., DANDREA, J., STEPHENSON, T.J. and SYMONDS, M.E., 2000. Proceedings of the Nutrition Society Proceedings of the Nutrition Society. 1A-80A
STEPHENSON, T.J. and BUDGE, H.J., 2000. The newborn. In: CHAMBERLAIN, G. and SLEER, P.J., eds., Turnbull's obstetrics Edinburgh: Churchill Livingstone.
CLARKE, L, FIRTH, K, HEASMAN, L, JUNIPER, D T, BUDGE, H, STEPHENSON, T and SYMONDS, M E, 2000. Influence of relative size at birth on growth and glucose homeostasis in twin lambs during juvenile life. Reproduction, Fertility and Development. 12(1-2), 69-73 BUDGE,H.J., 2000. Paediatric reference values. In: Pocket Paediatrics 2nd. Churchill Livingstone, Edinburgh, UK.
SYMONDS, ME, STEPHENSON, T, GARDNER, DS and BUDGE, H, Tissue Specific Adaptations To Nutrient Supply: More Than Just Epigenetics?