John Hammond

Contact

• workRoom W/E 1464 QMC West Block
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work0115 9249924-70607
• fax0115 970 9955
• john.hammond@nottingham.ac.uk

Research Summary

I have a program of work exploring how the liver heals in health and disease. Current projects investigate:

• How the liver regenerates following liver resection in man and how this alters in the presence of parenchymal liver disease (clinicaltrails.gov ref NCT01220986).
• Molecular signalling in post-resection liver failure.
• Small-for-size syndrome after major liver resection and strategies to modulate it.
• The pathophysiology of chemotherapy-induced liver injury, its detection and treatment.

Details of current PhD opportunities can be accessed via this link.

Recent Publications

• HAMMOND JS and LOBO DN, 2012. Emerging Roles For Biomaterials In The Treatment Of Liver Disease. Expert Review Of Medical Devices. 9(2), 181-8
• HAMMOND, JOHN S, GILBERT, THOMAS W, HOWARD, DANIEL, ZAITOUN, ABED, MICHALOPOULOS, GEORGE, SHAKESHEFF, KEVIN M, BECKINGHAM, IAN J and BADYLAK, STEPHEN F, 2011. Scaffolds containing growth factors and extracellular matrix induce hepatocyte proliferation and cell migration in normal and regenerating rat liver. Journal of hepatology. 54(2), 279-87
• HAMMOND, J S, GUHA, I N, BECKINGHAM, I J and LOBO, D N, 2011. Prediction, prevention and management of postresection liver failure. The British Journal Of Surgery.
• AMESUR, NIKHIL, HAMMOND, JOHN S, ZAJKO, ALBERT B, GELLER, DAVID A and GAMBLIN, T CLARK, 2009. Management of unresectable symptomatic focal nodular hyperplasia with arterial embolization. Journal of vascular and interventional radiology : JVIR. 20(4), 543-7

• View all publications

Past Research

I carried out my intercalated honours research with Sir John Savill exploring the regulation of NFκ​B in glomerulonephritis. Following pre-registration and basic surgical training I undertook my PhD (Scaffolds for Liver Tissue Engineering) as a collaborative project with Professor Kevin Shakesheff (School of Pharmacy, Nottingham) Professor Steve Badylak (McGowan Institute for Regenerative Medicine, Pittsburgh) and Professor Brian Rowlands/Mr Ian Beckingham (Division of Gastrointestinal Surgery, Nottingham). The work was funded by the Wellcome Trust and was awarded a Royal College of Surgeons of England Research Fellowship.

• HAMMOND JS and LOBO DN, 2012. Emerging Roles For Biomaterials In The Treatment Of Liver Disease. Expert Review Of Medical Devices. 9(2), 181-8
• HAMMOND, JOHN S, GILBERT, THOMAS W, HOWARD, DANIEL, ZAITOUN, ABED, MICHALOPOULOS, GEORGE, SHAKESHEFF, KEVIN M, BECKINGHAM, IAN J and BADYLAK, STEPHEN F, 2011. Scaffolds containing growth factors and extracellular matrix induce hepatocyte proliferation and cell migration in normal and regenerating rat liver. Journal of hepatology. 54(2), 279-87
• HAMMOND, J S, GUHA, I N, BECKINGHAM, I J and LOBO, D N, 2011. Prediction, prevention and management of postresection liver failure. The British Journal Of Surgery.
• AMESUR, NIKHIL, HAMMOND, JOHN S, ZAJKO, ALBERT B, GELLER, DAVID A and GAMBLIN, T CLARK, 2009. Management of unresectable symptomatic focal nodular hyperplasia with arterial embolization. Journal of vascular and interventional radiology : JVIR. 20(4), 543-7
• BROOKS, ADAM J, HAMMOND, JOHN S, GIRLING, KEITH and BECKINGHAM, IAN J, 2007. The effect of hepatic vascular inflow occlusion on liver tissue pH, carbon dioxide, and oxygen partial pressures: defining the optimal clamp/release regime for intermittent portal clamping. The Journal of surgical research. 141(2), 247-51
• HAMMOND, JOHN S, BECKINGHAM, IAN J and SHAKESHEFF, KEVIN M, 2006. Scaffolds for liver tissue engineering. Expert Review of Medical Devices. 3(1), 21-7
• HAMMOND, J S, JACKSON, L, ZAITOUN, A B, ROWLANDS, B J and AITHAL, G P, 2005. When acquired thrombophilia mattered. Gut. 54(8), 1204-5
• MAXWELL-ARMSTRONG C, BROOKS A, FIELD M, HAMMOND J and ABERCROMBIE J, 2002. Diagnostic Peritoneal Lavage Analysis: Should Trauma Guidelines Be Revised? Emergency Medicine Journal : Emj. 19(6), 524-5