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School of Clinical Sciences
   
   
  
 

Natalia Dovlatova

Researcher, Faculty of Medicine & Health Sciences

Contact

  • workRoom S/D 2108, Cardiovascular Medicine, D Floor South Block, Queen's Medical Centre, Nottingham, NG7 2UH
  • work0115 823 1019
  • fax0115 823 1017

Expertise Summary

I have substantial experience in utilizing multiple techniques to assess platelet aggregation, flow cytometry, immunoblotting and confocal microscopy.

Research Summary

My research is focused on platelet function in normal and pathological conditions, with particular interest in the role of platelet receptors in the regulation of platelet function. My current work… read more

Recent Publications

Current Research

My research is focused on platelet function in normal and pathological conditions, with particular interest in the role of platelet receptors in the regulation of platelet function. My current work mainly includes the assessment of platelet functionality, platelet inhibition by specific antagonists and their properties and investigation of a novel purine receptor on platelets.

  • DOVLATOVA, N., WIJEYERATNE, Y.D., FOX, S.C., MANOLOPOULOS, P., JOHNSON, A.J., WHITE, A.E., LATIF, L., RALEVIC, V. and HEPTINSTALL, S., 2009. Detection of P2Y14 receptor protein on platelets and investigation of the role of P2Y14 in platelet function. J Thromb Haemostas. Supplement 2, WE-045
  • HEPTINSTALL, STAN, ESPINOSA, DAVID IYU, MANOLOPOULOS, PANAGIOTIS, GLENN, JACKIE R, WHITE, ANN E, JOHNSON, ANDREW, DOVLATOVA, NATALIA, FOX, SUE C, MAY, JANE A, HERMANN, DAVID, MAGNUSSON, OLAFUR and STEFAN, 2008. DG-041 inhibits the EP3 prostanoid receptor--a new target for inhibition of platelet function in atherothrombotic disease. Platelets. 19(8), 605-13
  • DOVLATOVA, NATALIA, WIJEYERATNE, YANUSHI D, FOX, SUSAN C, MANOLOPOULOS, PANAGIOTIS, JOHNSON, ANDREW J, WHITE, ANN E, LATIF, M LIAQUE, RALEVIC, VERA and HEPTINSTALL, STANLEY, 2008. Detection of P2Y(14) protein in platelets and investigation of the role of P2Y(14) in platelet function in comparison with the EP(3) receptor. Thrombosis and Haemostasis. 100(2), 261-70
  • MANOLOPOULOS, P., GLENN, J.R., FOX, S.C., MAY, J.A., DOVLATOVA, N.L., TANG, S.W., THOMAS, N.R., RALEVIC, V. and HEPTINSTALL, S., 2008. Acyl derivatives of coenzyme A inhibit platelet function via antagonism at P2Y(1) and P2Y(12) receptors: A new finding that may influence the design of anti-thrombotic agents Platelets. 19(2), 134-145
  • JOHNSON, A, DOVLATOVA, N and AND HEPTINSTALL, H., 2008. Multiple electrode aggregometry and P2Y12 antagonists Thrombosis and Haemostasis. 99(6), 1127-1129
  • DOVLATOVA, N L, JAKUBOWSKI, J A, SUGIDACHI, A and HEPTINSTALL, S, 2008. The reversible P2Y antagonist cangrelor influences the ability of the active metabolites of clopidogrel and prasugrel to produce irreversible inhibition of platelet function. Journal of Thrombosis and Haemostasis: JTH. 6(7), 1153-9
  • WHITE, A., GLENN, J., FOX, S., JOHNSON, A., MYERS, B. and AND HEPTINSTALL, S., 2007. Reduced platelet aggregation to ADP and ATP in patients with leucocytosis is due to enhanced rates of adenine nucleotide metabolism mediated by the NTPDase CD39 Platelets. 18(1), 100
  • DOVLATOVA, N.L, JAKUBOWSKI, J.A, SUGIDACHI, A and AND HEPTINSTALL, S., 2007. Competition between reversible and irreversible P2Y12 antagonists and its influence on ADP-mediated platelet activation. Journal of Thrombosis and Haemostasis: JTH. 5(Supplement 2), P-S-340
  • HEPTINSTALL, S., MANOLOPOULOS, M., GLENN, J.R., FOX, S.C., MAY, J.A., DOVLATOVA, N., TANG, S-W., BAUER, N., HESSE, M., THOMAS, N.R. and RALEVIC, V., 2006. Acyl derivatives of coenzyme A inhibit ADP-induced platelet function via antagonism at P2Y1 and P2Y12 receptors. Purinergic Signalling. 2, 92-93
  • BURIACHKOVSKAIA, L I, POLIAKOVA, E O, ZORIN, A V, UCHITEL', I A, DOVLATOVA, N L, MASENKO, V P, SUMAROKOV, A B, KADUSHINA, E B, KUZENTSOVA, T A, POGORELOVA, T E and CHAZOV, E I, 2006. [Platelet activation and inflammation markers in patients with coronary heart disease and depression] TerapevticheskiÄ­ arkhiv. 78(10), 9-14

School of Clinical Sciences

D Floor, East Block
Queen's Medical Centre
Nottingham, NG7 2UH

telephone: +44 (0) 115 823 0695
fax: +44 (0) 115 823 0704
email: scs-enquiries@nottingham.ac.uk