Biotechnology and Biological Sciences Doctoral Training Programme
   
   
  

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Please note the list of projects available will be updated with additional projects, so please check frequently. Project details may also be subject to change before September 2018.

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Transcription factor regulation by ubiquitination – molecular basis of how to activate or deactivate

Description
We will use structural biology tools to investigate the effect of mono-ubiquitination on the structure and interactions using biochemical and biophysical methods. In a second line of investigation we will characterise the interaction with the deubiquitinating enzyme USP17

Generation and characterisation of different human macrophage subsets using magnetic cell sorting, fluorescent microscopy and ELSIA

Description
Generation and characterisation of different human macrophage subsets using magnetic cell sorting, fluorescent microscopy and ELSIA

Global metabolite profiling of different human macrophage subsets using advanced metabolomics methods

Description
By applying advanced analytical tools we can gain improved understanding into the cellular response of macrophages and ultimately immune response. The project can also underpin the development of new tools for immune modulation in addition to enhanced understanding of biological mechanisms of macrophage behaviour.

Generation and characterisation of nanoparticles with different size and shape

Description
By applying advanced analytical tools we can gain improved understanding into the cellular response of macrophages and ultimately immune response. The project can also underpin the development of new tools for immune modulation in addition to enhanced understanding of biological mechanisms of macrophage behaviour.
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Biotechnology and Biological Sciences Doctoral Training Programme

The University of Nottingham
University Park
Nottingham, NG7 2RD

Tel: +44 (0) 115 8466946
Email: bbdtp@nottingham.ac.uk