Biotechnology and Biological Sciences Doctoral Training Programme
   
   
  

Industrial Biotechnology and the Bioeconomy projects

 

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Please note that the list of projects available will be increased over the next few weeks so please check frequently. Project details may also be subject to change before September 2017.

 

BBSRC Doctoral Training Partnerships

 

 

 

View all Industrial Biotechnology and the Bioeconomy projects

Pentose to products: towards a sustainable bioeconomy

Description
Most of the current bio-based routes to manufacture chemicals utilise glucose. Unfortunately, glucose is produced mainly from human foodstuffs and its utilisation for chemicals and fuels is becoming unsustainable. C5 sugars such as xylose and arabinose, readily available from non-food, agricultural wastes, provide a much better alternative.

Rational design of sequence determinants of therapeutic mRNA stability

Description
The project will provide new information about the regulation of mRNA stability that is relevant for the design of mRNA therapeutics. Training includes protein expression and purification, in vitro transcription, mammalian cell culture, RNA transfection and reporter assays

One ring to rule them all: circular RNAs to make spider silk

Description
The PhD project will focus initially on using circular RNAs to develop a new type of flexible and adaptable expression system. Building on previous work in the lab, and also on their own work during the rotation project, students will combine standard molecular biology tools with cutting edge RNA biology applications to engineer plasmid constructs for bacterial and eukaryotic expression of proteins.

Structure-guided enzyme engineering to enhance the biocatalysis toolbox

Description
The aim of this project is to gain a detailed molecular understanding of selected biocatalysts of the transaminase and amine oxidase family in order to optimize them by protein engineering for selective chemical transformations.

Characterisation and engineering of a key regulator in butanol-producing clostridia

Description
Characterisation and engineering of a key regulator in butanol-producing clostridia
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Biotechnology and Biological Sciences Doctoral Training Programme

The University of Nottingham
University Park
Nottingham, NG7 2RD

Tel: +44 (0) 115 8466946
Email: bbdtp@nottingham.ac.uk