Biotechnology and Biological Sciences Doctoral Training Programme
   
   
  

Molecules, Cells and Organisms projects

 

Please note that the list of projects available will be increased over the next few weeks so please check frequently. Project details may also be subject to change before September 2018.

 

BBSRC Doctoral Training Partnerships

 

 

 

View all Molecules, Cells and Organisms projects

Investigating the differential regulation of cell surface GAG in breast cancer: Using NGPD to isolate cancer cell specific peptides

Description
In this project, we propose to identify cell-type specific variants in breast cancer patient samples in a high-throughput manner using phage display-libraries (1010 phage) of GET peptides and next-generation sequencing (NGS) in a process called next generation phage display (NGPD).

Exploring the Function of Gene Regulators by CRISPR CAS9 Genome Editing

Description
This project will utilise these cell lines in 'rescue' experiments by re-expression of wild type or mutant KAT6A to determine function. We will generate mutations in different functional domains in KAT6A to assess their requirement for regulation of a panel target genes by qPCR.
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Biotechnology and Biological Sciences Doctoral Training Programme

The University of Nottingham
University Park
Nottingham, NG7 2RD

Tel: +44 (0) 115 8466946
Email: bbdtp@nottingham.ac.uk