Biotechnology and Biological Sciences Doctoral Training Programme
   
   
  

Real time sequencing for assembly of complex genomic regions using selective sequencing

 

Project title

Real time sequencing for assembly of complex genomic regions using selective sequencing

Project description

Sequencing technology has advanced rapidly in the last 15 years. The advent of nanopore sequencing introduces truly portable, hand-held sequencing devices which have now been used in every imaginable location from the deep sea to the international space station.At Nottingham we have been at the forefront of tools development for the MinION sequencer, in particular exploiting real time interaction using “Read Until”. This project aims to look at how these technologies can be exploited to allow us to sequence and assemble complex regions of a range of genomes. This is a wet and dry project. The student will be involved in sequencing and analysis, and will have access to local expertise through DeepSeq, the University of Nottingham next generation sequencing facility and ADAC, the Advanced Data Analysis Centre.

There will be the opportunity to learn, apply and develop bioinformatics approaches. The applicant will need to embrace learning new laboratory techniques and collaborating with scientists from other disciplines.  

School

School of Life Sciences

Supervisor/s

Dr Matt Loose: Matt.loose@nottingham.ac.uk

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Biotechnology and Biological Sciences Doctoral Training Programme

The University of Nottingham
University Park
Nottingham, NG7 2RD

Tel: +44 (0) 115 8466946
Email: bbdtp@nottingham.ac.uk