Real time sequencing for assembly of complex genomic regions using selective sequencing
Sequencing technology has advanced rapidly in the last 15 years. The advent of nanopore sequencing introduces truly portable, hand-held sequencing devices which have now been used in every imaginable location from the deep sea to the international space station.
At Nottingham we have been at the forefront of tools development for the MinION sequencer, in particular exploiting real time interaction using 'Read Until'.
This project aims to look at how these technologies can be exploited to allow us to sequence and assemble complex regions of a range of genomes. This is a wet and dry project. The student will be involved in sequencing and analysis, and will have access to local expertise through DeepSeq, the University of Nottingham next generation sequencing facility and ADAC, the Advanced Data Analysis Centre.
There will be the opportunity to learn, apply and develop bioinformatics approaches. The applicant will need to embrace learning new laboratory techniques and collaborating with scientists from other disciplines.
This project will be based in the School of Life Sciences, and will be supervised by Dr Matt Loose.
Applications are invited from students who have, or expect to graduate with a first or upper-second UK honours degree, or equivalent qualifications gained outside the UK. Students with an appropriate Masters degree are particularly encouraged to apply.
Funding is available for four years from October 2017. A full award would be fees plus an annual stipend. This is set by the Research Councils and was £14296 for 2016/17.
Eligibility for full funding is restricted to UK students.
How to apply
Applicants should download the application and reference forms from this page. Applications should include:
- a fully completed application form
- a CV of no more than two A4 pages
- a transcript of module marks achieved at the time of submission
- two references
Application forms and CVs should be named in the following format:
- SURNAME-initial-DTP_BBSRC_iCASE-application (.docx or .pdf)
- SURNAME-initial-BBSRC_iCASE-cv (.docx or.pdf)
For example: SMITH-A-BBSRC_iCASE-application.doc
Your completed forms should be sent via email with the subject line ‘BBSRC iCASE Studentship’ to Matt.Loose@nottingham.ac.uk by the deadline: noon, 31 March 2017.
References should be sent directly from the referees to Dr Matt Loose by the deadline: noon, 31 March 2017. Please note it is the applicant’s responsibility to ensure that the references are sent in good time for the deadline. Further details are on the reference form.
School of Life Sciences
Dr Matt Loose
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