Lynn Bedford

Contact

• workRoom D38 The University of Nottingham Medical School
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work0115 82 30099
• fax0115 82 30103
• lynn.bedford@nottingham.ac.uk

Selected Publications

• BEDFORD, L, HAY, D, DEVOY, A, PAINE, S, POWE, DG, SETH, R, GRAY, T, TOPHAM, I, FONE, K, REZVANI, N, MEE, M, SOANE, T, LAYFIELD, R, SHEPPARD, PW, EBENDAL, T, USOSKIN, D, LOWE, J and MAYER, RJ, 2008. Depletion Of 26S Proteasomes In Mouse Brain Neurons Causes Neurodegeneration And Lewy-Like Inclusions Resembling Human Pale Bodies Journal of Neuroscience. 28(33), 8189-8198
• BEDFORD, L, LAYFIELD, R, MAYER, RJ, PENG, JM and XU, P, 2011. Diverse Polyubiquitin Chains Accumulate Following 26S Proteasomal Dysfunction In Mammalian Neurones Neuroscience Letters. 491(1), 44-47
• BEDFORD, L, LOWE, J, DICK, LR, MAYER, RJ and BROWNELL, JE, 2011. Ubiquitin-Like Protein Conjugation And The Ubiquitin-Proteasome System As Drug Targets
• WILLIAMSON, R, VAN AALTEN, L, MANN, DMA, PLATT, B, PLATTNER, F, BEDFORD, L, MAYER, J, HOWLETT, D, USARDI, A, SUTHERLAND, C and COLE, AR, 2011. Crmp2 Hyperphosphorylation Is Characteristic Of Alzheimer's Disease And Not A Feature Common To Other Neurodegenerative Diseases Journal Of Alzheimers Disease. 27(3), 615-625

• View all publications

• BEDFORD, L, LAYFIELD, R, MAYER, RJ, PENG, JM and XU, P, 2011. Diverse Polyubiquitin Chains Accumulate Following 26S Proteasomal Dysfunction In Mammalian Neurones Neuroscience Letters. 491(1), 44-47
• BEDFORD, L, LOWE, J, DICK, LR, MAYER, RJ and BROWNELL, JE, 2011. Ubiquitin-Like Protein Conjugation And The Ubiquitin-Proteasome System As Drug Targets
• WILLIAMSON, R, VAN AALTEN, L, MANN, DMA, PLATT, B, PLATTNER, F, BEDFORD, L, MAYER, J, HOWLETT, D, USARDI, A, SUTHERLAND, C and COLE, AR, 2011. Crmp2 Hyperphosphorylation Is Characteristic Of Alzheimer's Disease And Not A Feature Common To Other Neurodegenerative Diseases Journal Of Alzheimers Disease. 27(3), 615-625
• PAINE, S, LOWE, J, BEDFORD, L and MAYER, RJ, 2011. Can Neurodegeneration Be Separated From Neuropathological Hallmarks Of Chronic Idiopathic Human Neurodegenerative Disease? A Perspective From Modelling! Biochemical Society Transactions. 39, 917-919
• ROGERS, N, PAINE, S, BEDFORD, L and LAYFIELD, R, 2010. Review: The Ubiquitin-Proteasome System: Contributions To Cell Death Or Survival In Neurodegeneration
• BEDFORD, L, PAINE, SML, MEE, M, LOWE, JS and MAYER, RJ, 2009. The ubiquitin proteasome system is involved in neuro-degeneration and inclusion body formation linked to Parkinson's disease In: 110th Annual Meeting of the British-Neuropathological-Society. 13-13
• PAINE, S, BEDFORD, L, THORPE, JR, MAYER, RJ, CAVEY, JR, BAJAJ, N, SHEPPARD, PW, LOWE, J and LAYFIELD, R, 2009. Immunoreactivity To Lys63-Linked Polyubiquitin Is A Feature Of Neurodegeneration Neuroscience Letters. 460(3), 205-208
• BEDFORD, L, PAINE, S, REZVONI, N, MEE, M, LOWE, J and MAYER, RJ, 2009. The UPS And Autophagy In Chronic Neurodegenerative Disease Six Of One And Half A Dozen Of The Other-Or Not? Autophagy. 5(2), 224-227
• BEDFORD, L, HAY, D, DEVOY, A, PAINE, S, POWE, DG, SETH, R, GRAY, T, TOPHAM, I, FONE, K, REZVANI, N, MEE, M, SOANE, T, LAYFIELD, R, SHEPPARD, PW, EBENDAL, T, USOSKIN, D, LOWE, J and MAYER, RJ, 2008. Depletion Of 26S Proteasomes In Mouse Brain Neurons Causes Neurodegeneration And Lewy-Like Inclusions Resembling Human Pale Bodies Journal of Neuroscience. 28(33), 8189-8198
• BEDFORD, L, HAY, D, PAINE, S, REZVANI, N, MEE, M, LOWE, J and MAYER, RJ, 2008. Is Malfunction Of The Ubiquitin Proteasome System The Primary Cause Of Alpha-Synucleinopathies And Other Chronic Human Neurodegenerative Disease?
• LAYFIELD, R, LOWE, J and BEDFORD, L, 2005. The Ubiquitin-Proteasome System And Neurodegenerative Disorders
• BEDFORD, L, WALKER, R, KONDO, T, VAN CRUCHTEN, I, KING, ER and SABLITZKY, F, 2005. Id4 Is Required For The Correct Timing Of Neural Differentiation Developmental Biology. 280(2), 386-395