Peter Mansell
Clinical Associate Professor in Human Metabolism, Faculty of Medicine & Health Sciences
Contact
- workRoom B16 The University of Nottingham Medical School
Queen's Medical Centre
Nottingham
NG7 2UH
UK - work0115 82 30199
- fax0115 82 30142
- peter.mansell@nottingham.ac.uk
Biography
I initially read chemistry at Oxford University, obtaining a first class honours degree and then moved on to undertake research for a Doctor of Philosophy degree in Physical Chemistry. I decided that my long-term career interests lay elsewhere and studied for a medical degree in Bristol, qualifying with honours in 1982. I then passed Membership of the Royal College of Physicians examination before moving to Nottingham as clinical registrar in diabetes and endocrinology and as Wellcome fellow in the University Department of Physiology and Pharmacology, where I obtained a Doctor of Medicine degree with a thesis entitled 'Undernutrition, Thermogenesis and Thermoregulation'. I then moved to Bath and Southampton as a clinical senior registrar in medicine, diabetes and endocrinology and obtained a consultant post in Salisbury. In 1998 I moved back to Nottingham as an NHS consultant physician and was able to retain an interest in research. In 2007 I transferred to a post of Clinical Associate Professor in Human Metabolism at the University of Nottingham and clinical director of the David Greenfield Human Physiology Unit in the School of Biomedical Sciences. I retain a with a part-time clinical commitment. with Nottingham University Hospitals NHS Trust.
Expertise Summary
My principal interest and expertise is in smaller scale metabolic and physiological studies investigating the mechanisms underlying disease processes and their treatments, particularly diabetes. I undertake 'whole body' studies in both healthy volunteers and patients and, in collaboration, use techniques including non-invasive cardio-vascular measurements, magnetic resonance spectroscopy, respiratory gas exchange and other physiological methods.
I also have an interest in diabetes education, particularly for patients with type 1 diabetes
Research Summary
My current research is in
1) Understanding the patho-physiological processes which lead to adverse outcome in pregnancy in women with type 1 diabetes.
2) Developing, studying and refining the education provided to people with type 1 diabetes to allow them to manage their condition optimally - with particular reference to the Dose Adjustment For Normal Eating (DAFNE) education programme
3) Studies in nutrition, exercise and metabolism investigating the mechanisms underlying insulin resistance, the 'metabolic syndrome' and early Type 2 diabetes
Recent Publications
MENDIS B, SIMPSON E, MACDONALD I and MANSELL P, 2012. Investigation Of The Haemodynamic Effects Of Exenatide In Healthy Male Subjects. British Journal Of Clinical Pharmacology. (In Press.)
KHOO, E, WALLIS, J, TSINTZAS, K, MACDONALD, I and MANSELL, P, 2010. Effects of exenatide on circulating glucose, insulin, glucagon, cortisol and catecholamines in healthy volunteers during exercise. Diabetologia. 53, 139-143
KHOO, ERIC Y H, RISLEY, JAMES, ZAITOUN, ABED M, EL-SHEIKH, MOHAMED, PAISEY, RICHARD B, ACHESON, AUSTIN G and MANSELL, PETER, 2009. Alström syndrome and cecal volvulus in 2 siblings. The American journal of the medical sciences. 337(5), 383-5