WALL, BT, STEPHENS, FB, MARIMUTHU, K, CONSTANTIN-TEODOSIU, D, MACDONALD, IA and GREENHAFF, PL, 2012. Acute Pantothenic Acid And Cysteine Supplementation Does Not Affect Muscle Coenzyme A Content, Fuel Selection, Or Exercise Performance In Healthy Humans Journal Of Applied Physiology. 112(2), 272-278 JAMES V*, FOXLER DE*, BRIDGE KS*, WEBB TM*, MEE M, WONG SCK, FENG Y, CONSTANTIN-THEODOSIU D, PETURSDOTTIR TE, BJORNSSON J, INGVARSSON S, RATCLIFFE PJ, LONGMORE GD and SHARP TV, 2012. The Limd1 Protein Bridges An Association Between The Prolyl Hydroxylases And Vhl To Repress Hif-1 Activity. Nature Cell Biology. 14(2), 201-8 WALL, BENJAMIN T, STEPHENS, FRANCIS B, CONSTANTIN-TEODOSIU, DUMITRU, MARIMUTHU, KANAGARAJ, MACDONALD, IAN A and GREENHAFF, PAUL L, 2011. Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans: the dual role of muscle carnitine in exercise metabolism. The Journal of physiology. WALL BT, STEPHENS FB, MARIMUTHU K, CONSTANTIN-TEODOSIU D, MACDONALD IA and GREENHAFF PL, 2011. Acute Pantothenic Acid And Cysteine Supplementation Does Not Affect Muscle Co-Enzyme A Content, Fuel Selection Or Exercise Performance In Healthy Humans. Journal Of Applied Physiology (Bethesda, Md. : 1985). (In Press.)
WALL, BT, STEPHENS, FB, CONSTANTIN-TEODOSIU, D, MARIMUTHU, K, MACDONALD, IA and GREENHAFF, PL, 2011. Increasing Muscle Carnitine Content Alters Muscle Fuel Metabolism And Improves Exercise Performance In Humans
WALL, BT, STEPHENS, FB, CONSTANTIN-TEODOSIU, D, MARIMUTHU, K, MACDONALD, IA and GREENHAFF, PL, 2011. Chronic Oral Ingestion Of L-Carnitine And Carbohydrate Increases Muscle Carnitine Content And Alters Muscle Fuel Metabolism During Exercise In Humans Journal Of Physiology-London. 589(4), 963-973 AWAD, SHERIF, CONSTANTIN-TEODOSIU, DUMITRU, CONSTANTIN, DESPINA, ROWLANDS, BRIAN J, FEARON, KENNETH C H, MACDONALD, IAN A and LOBO, DILEEP N, 2010. Cellular mechanisms underlying the protective effects of preoperative feeding: a randomized study investigating muscle and liver glycogen content, mitochondrial function, gene and protein expression. Annals Of Surgery. 252(2), 247-53 AWAD, SHERIF, STEPHENSON, MARY C, PLACIDI, ELISA, MARCIANI, LUCA, CONSTANTIN-TEODOSIU, DUMITRU, GOWLAND, PENNY A, SPILLER, ROBIN C, FEARON, KENNETH C H, MORRIS, PETER G, MACDONALD, IAN A and LOBO, DILEEP, 2010. The effects of fasting and refeeding with a 'metabolic preconditioning' drink on substrate reserves and mononuclear cell mitochondrial function. Clinical Nutrition.
CROSSLAND, HANNAH, CONSTANTIN-TEODOSIU, DUMITRU, GREENHAFF, PAUL L and GARDINER, SHEILA M, 2010. Low-dose dexamethasone prevents endotoxaemia-induced muscle protein loss and impairment of carbohydrate oxidation in rat skeletal muscle. The Journal of physiology. 588(pt 8), 1333-1347
FORMENTI, FEDERICO, CONSTANTIN-TEODOSIU, DUMITRU, EMMANUEL, YASO, CHEESEMAN, JANE, DORRINGTON, KEITH L, EDWARDS, LINDSAY M, HUMPHREYS, SANDY M, LAPPIN, TERENCE R J, MCMULLIN, MARY F and MCNAMARA, CHRISTO, 2010. Regulation of human metabolism by hypoxia-inducible factor. Proceedings of the National Academy of Sciences of the United States of America. 107(28), 12722-7 ALOYSIUS, MARK M, ZAITOUN, ABED M, BATES, TIMOTHY E, ILYAS, MOHAMMAD, CONSTANTIN-TEODOSIU, DUMITRU, ROWLANDS, BRIAN J and LOBO, DILEEP N, 2010. Immunohistochemical expression of mitochondrial membrane complexes (MMCs) I, III, IV and V in malignant and benign periampullary epithelium: a potential target for drug therapy of periampullary cancer? BMC Cancer. 10(1), 80
MARWOOD, SIMON, CONSTANTIN-TEODOSIU, DUMITRU, CASEY, EDEL, WHYTE, MARTIN, BOOBIS, LESLIE and BOWTELL, JO, 2010. No acetyl group deficit is evident at the onset of exercise at 90% of maximal oxygen uptake in humans. Journal of sports sciences. 1-13
AWAD, S, CONSTANTIN-TEODOSIU, D, FEARON, KCH, MACDONALD, IA and LOBO, DN, 2010. Cellular mechanisms underlying the protective effects of preoperative feeding: a randomized study investigating muscle and liver glycogen content, mitochondrial function and gene expression In: Electronic Poster of Distinction in Association-of-Surgeons-of-Great-Britain-and-Ireland-International-Surgical-Congress. 2-2
AWAD, S, STEPHENSON, MC, PLACIDI, E, MARCIANI, L, CONSTANTIN-TEODOSIU, D, GOWLAND, PA, SPILLER, RC, FEARON, KCH, MORRIS, PG, MACDONALD, IA and LOBO, DN, 2010. The Effects Of Fasting And Refeeding With A 'Metabolic Preconditioning' Drink On Substrate Reserves And Mononuclear Cell Mitochondrial Function AWAD, S, CONSTANTIN-TEODOSIU, D, CONSTANTIN, D, ROWLANDS, BJ, FEARON, KCH, MACDONALD, IA and LOBO, DN, 2010. Cellular Mechanisms Underlying The Protective Effects Of Preoperative Feeding A Randomized Study Investigating Muscle And Liver Glycogen Content, Mitochondrial Function, Gene And Protein Expression Annals Of Surgery. 252(2), 247-253 FORMENTI, F, CONSTANTIN-TEODOSIU, D, EMMANUEL, Y, CHEESEMAN, J, DORRINGTON, KL, EDWARDS, LM, HUMPHREYS, SM, LAPPIN, TRJ, MCMULLIN, MF, MCNAMARA, CJ, MILLS, W, MURPHY, JA, O'CONNOR, DF, PERCY, MJ, RATCLIFFE, PJ, SMITH, TG, TREACY, M, FRAYN, KN, GREENHAFF, PL, KARPE, F, CLARKE, K and ROBBINS, PA, 2010. Regulation Of Human Metabolism By Hypoxia-Inducible Factor Proceedings Of The National Academy Of Sciences Of The United States Of America. 107(28), 12722-12727 ALOYSIUS, MM, ZAITOUN, AM, BATES, TE, ILYAS, M, CONSTANTIN-TEODOSIU, D, ROWLANDS, BJ and LOBO, DN, 2010. Immunohistochemical Expression Of Mitochondrial Membrane Complexes (Mmcs) I, Iii, Iv And V In Malignant And Benign Periampullary Epithelium: A Potential Target For Drug Therapy Of Periampullary Cancer? Bmc Cancer. 10, - MARWOOD, S, CONSTANTIN-TEODOSIU, D, CASEY, E, WHYTE, M, BOOBIS, L and BOWTELL, J, 2010. No Acetyl Group Deficit Is Evident At The Onset Of Exercise At 90% Of Maximal Oxygen Uptake In Humans Journal Of Sports Sciences. 28(3), 267-279 AWAD, SHERIF, CONSTANTIN-TEODOSIU, DUMITRU, MACDONALD, IAN A and LOBO, DILEEP N, 2009. Short-term starvation and mitochondrial dysfunction - a possible mechanism leading to postoperative insulin resistance. Clinical Nutrition. 28(5), 497-509
MURTON, AJ, ALAMDARI, N, GARDINER, SM, CONSTANTIN-TEODOSIU, D, LAYFIELD, R, BENNETT, T, GREENHAFF, PL, 2009. Effects of endotoxaemia on protein metabolism in rat fast-twitch skeletal muscle and myocardium. PloS One. 4(9), e6945 VOLLAARD, NIELS B J, CONSTANTIN-TEODOSIU, DIMITRU, FREDRIKSSON, KATARINA, ROOYACKERS, OLAV, JANSSON, EVA, GREENHAFF, PAUL L, TIMMONS, JAMES A and SUNDBERG, CARL JOHAN, 2009. Systematic analysis of adaptations in aerobic capacity and submaximal energy metabolism provides a unique insight into determinants of human aerobic performance. Journal of Applied Physiology. 106(5), 1479-86 MURTON, AJ, ALAMDARI, N, GARDINER, SM, CONSTANTIN-TEODOSIU, D, LAYFIELD, R, BENNETT, T and GREENHAFF, PL, 2009. Effects Of Endotoxaemia On Protein Metabolism In Rat Fast-Twitch Skeletal Muscle And Myocardium Plos One. 4(9), - VOLLAARD, NBJ, CONSTANTIN-TEODOSIU, D, FREDRIKSSON, K, ROOYACKERS, O, JANSSON, E, GREENHAFF, PL, TIMMONS, JA and SUNDBERG, CJ, 2009. Systematic Analysis Of Adaptations In Aerobic Capacity And Submaximal Energy Metabolism Provides A Unique Insight Into Determinants Of Human Aerobic Performance Journal Of Applied Physiology. 106(5), 1479-1486 MALLINSON, JE, CONSTANTIN-TEODOSIU, D, SIDAWAY, J, WESTWOOD, FR and GREENHAFF, PL, 2009. Blunted Akt/Foxo Signalling And Activation Of Genes Controlling Atrophy And Fuel Use In Statin Myopathy Journal Of Physiology-London. 587(1), 219-230 ALAMDARI, N, CONSTANTIN-TEODOSIU, D, MURTON, AJ, GARDINER, SM, BENNETT, T, LAYFIELD, R, GREENHAFF, PL, 2008. Temporal changes in the involvement of pyruvate dehydrogenase complex in muscle lactate accumulation during lipopolysaccharide infusion in rats. The Journal of Physiology. 586(6), 1767-75 CROSSLAND, HANNAH, CONSTANTIN-TEODOSIU, DUMITRU, GARDINER, SHEILA M, CONSTANTIN, DESPINA and GREENHAFF, PAUL L, 2008. A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle. The Journal of physiology. 586(Pt 22), 5589-600
CONSTANTIN-TEODOSIU,, BAKER,, CONSTANTIN, and GREENHAFF,, 2008. PPAR{delta} agonism inhibits skeletal muscle PDC activity, mitochondrial ATP production and force generation during prolonged contraction. The Journal of physiology.
MALLINSON,, CONSTANTIN-TEODOSIU,, SIDAWAY,, WESTWOOD, and GREENHAFF,, 2008. Blunted Akt/FOXO signalling and activation of genes controlling atrophy and fuel use in statin myopathy. The Journal of physiology.
CROSSLAND, H, CONSTANTIN-TEODOSIU, D, GARDINER, SM, CONSTANTIN, D and GREENHAFF, PL, 2008. A Potential Role For Akt/Foxo Signalling In Both Protein Loss And The Impairment Of Muscle Carbohydrate Oxidation During Sepsis In Rodent Skeletal Muscle Journal Of Physiology-London. 586(22), 5589-5600 ALAMDARI, N, CONSTANTIN-TEODOSIU, D, MURTON, AJ, GARDINER, SM, BENNETT, T, LAYFIELD, R and GREENHAFF, PL, 2008. Temporal Changes In The Involvement Of Pyruvate Dehydrogenase Complex In Muscle Lactate Accumulation During Lipopolysaccharide Infusion In Rats Journal Of Physiology-London. 586(6), 1767-1775 STEPHENS, FB, CONSTANTIN-TEODOSIU, D, LAITHWAITE, D, SIMPSON, EJ and GREENHAFF, PL, 2007. A threshold exists for the stimulatory effect of insulin on plasma L-carnitine clearance in humans. American Journal of Physiology: Endocrinology and Metabolism. 292, E637-41 STEPHENS, FB, EVANS, CE, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, 2007. Carbohydrate ingestion augments L-carnitine retention in humans. Journal of Applied Physiology. 102(3), 1065-70 BOWTELL, JL, MARWOOD, S, BRUCE, M, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, 2007. Tricarboxylic Acid Cycle Intermediate Pool Size - Functional Importance For Oxidative Metabolism In Exercising Human Skeletal Muscle
TSINTZAS, K, CHOKKALINGAM, K, JEWELL, K, NORTON, L, MACDONALD, IA and CONSTANTIN-TEODOSIU, D, 2007. Elevated Free Fatty Acids Attenuate The Insulin-Induced Suppression Of Pdk4 Gene Expression In Human Skeletal Muscle: Potential Role Of Intramuscular Long-Chain Acyl-Coenzyme A Journal Of Clinical Endocrinology & Metabolism. 92(10), 3967-3972 CONSTANTIN, D, CONSTANTIN-TEODOSIU, D, LAYFIELD, R, TSINTZAS, K, BENNETT, AJ and GREENHAFF, PL, 2007. Ppar Delta Agonism Induces A Change In Fuel Metabolism And Activation Of An Atrophy Programme, But Does Not Impair Mitochondrial Function In Rat Skeletal Muscle Journal Of Physiology-London. 583(1), 381-390 STEPHENS, FB, EVANS, CE, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, 2007. Carbohydrate Ingestion Augments L-Carnitine Retention In Humans Journal Of Applied Physiology. 102(3), 1065-1070 STEPHENS, FB, CONSTANTIN-TEODOSIU, D, LAITHWAITE, D, SIMPSON, EJ and GREENHAFF, PL, 2007. A Threshold Exists For The Stimulatory Effect Of Insulin On Plasma L-Carnitine Clearance In Humans American Journal Of Physiology-Endocrinology And Metabolism. 292(2), E637-E641 STEPHENS, F.B., CONSTANTIN-TEODOSIU, D., LAITHWAITE, D., SIMPSON, E.J and GREENHAFF, P.L, 2006. Insulin stimulates L-carnitine accumulation in human skeletal muscle. FASEB Journal. 20(2), 377-379
STEPHENS,F.B., CONSTANTIN-TEODOSIU,D., LAITHWAITE,D., SIMPSON,E.J. and GREENHAFF,P.L, 2006. An acute increase in skeletal muscle carnitine content alters fuel metabolism in resting human skeletal muscle. Journal of Clinical Endocrinology and Metabolism. 91(12), 5013-5018 BAKER, D.J., CONSTANTIN-TEODOSIU, D., JONES, S.W., TIMMONS, J.A. and GREENHAFF, P.L, 2006. Chronic treatment with the beta(2)-adrenoceptor agonist prodrug BRL-47672 impairs rat skeletal muscle function by inducing a comprehensive shift to a faster muscle phenotype. Journal of Pharmacology and Experimental Therapeutics. 319(1), 439-446 STEPHENS, FB, CONSTANTIN-TEODOSIU, D, LAITHWAITE, D, SIMPSON, EJ and GREENHAFF, PL, 2006. Insulin Stimulates L-Carnitine Accumulation In Human Skeletal Muscle Faseb Journal. 20(2), 377-379 STEPHENS, FB, CONSTANTIN-TEODOSIU, D, LAITHWAITE, D, SIMPSON, EJ and GREENHAFF, PL, 2006. An Acute Increase In Skeletal Muscle Carnitine Content Alters Fuel Metabolism In Resting Human Skeletal Muscle Journal Of Clinical Endocrinology & Metabolism. 91(12), 5013-5018 BAKER, DJ, CONSTANTIN-TEODOSIU, D, JONES, SW, TIMMONS, JA and GREENHAFF, PL, 2006. Chronic Treatment With The Beta(2)-Adrenoceptor Agonist Prodrug Brl-47672 Impairs Rat Skeletal Muscle Function By Inducing A Comprehensive Shift To A Faster Muscle Phenotype Journal Of Pharmacology And Experimental Therapeutics. 319(1), 439-446 MURTON, AJ, ALAMDARI, N, CONSTANTIN-TEODOSIU, D, GARDINER, SM, BENNETT, T, LAYFIELD, R and GREENHAFF, PL, 2006. Lipopolysaccharide-induced transcriptional upregulation of interleukin-6 and tumor necrosis factor-alpha precedes muscle specific expression of the ubiquitin ligases, MAFbx and MuRF1 in the rat extensor digitorum longus muscle In: Experimental Biology 2006 Meeting. A390-A390
ALAMDARI, N, MURTON, AJ, CONSTANTIN-TEODOSIU, D, GARDINER, SM, BENNETT, T, LAYFIELD, R and GREENHAFF, PL, 2006. Lipopolysaccharide-mediated inhibition of pyruvate dehydrogenase activity in rat extensor digitorum longus muscle In: Experimental Biology 2006 Meeting. A816-A816
ROBERTS, P.A., LOXHAM, S.J.G., POUCHER, S.M., CONSTANTIN-TEODOSIU, D. and GREENHAFF, P.L, 2005. Acetyl-CoA provision and the acetyl group deficit at the onset of contraction in ischemic canine skeletal muscle. American Journal of Physiology: Endocrinology and Metabolism. 288(2), E327-334 VAN LOON, L. J. C., THOMASON-HUGHES, M., CONSTANTIN-TEODOSIU, D., KOOPMAN, R., GREENHAFF, P. L., HARDIE, D. G., KEIZER, H. A., SARIS, W. H. M. and WAGENMAKERS, A. J. M., 2005. Inhibition of adipose tissue lipolysis increases intramuscular lipid and glycogen use in vivo in humans American Journal of Physiology. VOL 289(NUMB 3), E482
STEPHENS, FB, CONSTANTIN-TEODOSIU, D, LAITHWAITE, D, SIMPSON, EJ and GREENHAFF, PL, 2005. Insulin Stimulates L-Carnitine Accumulation In Human Skeletal Muscle Faseb Journal. 19(14), 377-+ VAN LOON, LJC, THOMASON-HUGHES, M, CONSTANTIN-TEODOSIU, D, KOOPMAN, R, GREENHAFF, PL, HARDIE, DG, KEIZER, HA, SARIS, WHM and WAGENMAKERS, AJM, 2005. Inhibition Of Adipose Tissue Lipolysis Increases Intramuscular Lipid And Glycogen Use In Vivo In Humans American Journal Of Physiology-Endocrinology And Metabolism. 289(3), E482-E493 ROBERTS, PA, LOXHAM, SJG, POUCHER, SM, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, 2005. Acetyl-Coa Provision And The Acetyl Group Deficit At The Onset Of Contraction In Ischemic Canine Skeletal Muscle American Journal Of Physiology-Endocrinology And Metabolism. 288(2), E327-E334 TIMMONS, J.A., CONSTANTIN-TEODOSIU, D., POUCHER, S.M. and GREENHAFF, P.L, 2004. Acetyl group availability influences phosphocreatine degradation even during intense muscle contraction. Journal of Physiology. 561(3), 851-859 CONSTANTIN-TEODOSIU, D., PEIRCE, N.S., FOX, J. and GREENHAFF, P.L, 2004. Muscle pyruvate availability can limit the flux, but not activation, of the pyruvate dehydrogenase complex during submaximal exercise in humans. Journal of Physiology. 561(2), 647-655 GREENHAFF, P L, CAMPBELL-O'SULLIVAN, S P, CONSTANTIN-TEODOSIU, D, POUCHER, S M, ROBERTS, P A and TIMMONS, J A, 2004. Metabolic inertia in contracting skeletal muscle: a novel approach for pharmacological intervention in peripheral vascular disease. British Journal of Clinical Pharmacology. 57(3), 237-43 TIMMONS, JA, CONSTANTIN-TEODOSIU, D, POUCHER, SM and GREENHAFF, PL, 2004. Acetyl Group Availability Influences Phosphocreatine Degradation Even During Intense Muscle Contraction Journal Of Physiology-London. 561(3), 851-859 CONSTANTIN-TEODOSIU, D, PEIRCE, NS, FOX, J and GREENHAFF, PL, 2004. Muscle Pyruvate Availability Can Limit The Flux, But Not Activation, Of The Pyruvate Dehydrogenase Complex During Submaximal Exercise In Humans Journal Of Physiology-London. 561(2), 647-655 STEPHENS, F, CONSTANTIN-TEODOSIU, T and GREENHAFF, P, 2004. Insulin stimulates L-carnitine retention in humans In: Experimental Biology 2004 Meeting. A769-A770
GREENHAFF, PL, CAMPBELL-O'SULLIVAN, SP, CONSTANTIN-TEODOSIU, D, POUCHER, SM, ROBERTS, PA and TIMMONS, JA, 2004. Metabolic Inertia In Contracting Skeletal Muscle: A Novel Approach For Pharmacological Intervention In Peripheral Vascular Disease HESSELINK, M.K.C., GREENHAFF, P.L., CONSTANTIN-TEODOSIU, D., HULTMAN, E., SARIS, W.H.M., NIEUWLAAT, R., SCHAART, G., KORNIPS, E. and SCHRAUWEN, P, 2003. Increased uncoupling protein 3 content does not affect mitochondrial function in human skeletal muscle in vivo. Journal of Clinical Investigation. 111(4), 479-486 HESSELINK, MKC, GREENHAFF, PL, CONSTANTIN-TEODOSIU, D, HULTMAN, E, SARIS, WHM, NIEUWLAAT, R, SCHAART, G, KORNIPS, E and SCHRAUWEN, P, 2003. Increased Uncoupling Protein 3 Content Does Not Affect Mitochondrial Function In Human Skeletal Muscle In Vivo Journal Of Clinical Investigation. 111(4), 479-486 CONSTANTIN-TEODOSIU, D., YOUNG, S., WELLOCK, F., SHORT, A. H., BURDEN, R. P., MORGAN, A. G. and GREENHAFF, P. L., 2002. Gender and age differences in plasma carnitine, muscle strength, and exercise tolerance in haemodialysis patients Nephrology, Dialysis, Transplantation. 17(10), 1808-1813 ROBERTS, P.A., LOXHAM, S.J.G., POUCHER, S.M., CONSTANTIN-TEODOSIU, D. and GREENHAFF, P.L., 2002. The acetyl group deficit at the onset of contraction in ischaemic canine skeletal muscle. Journal of Physiology. 544(2), 591-602 GREENHAFF, P. L., CAMPBELL-O SULLIVAN, S. P., CONSTANTIN-TEODOSIU, D., POUCHER, S. M., ROBERTS, P. A. and TIMMONS, J. A., 2002. An acetyl group deficit limits mitochondrial ATP production at the onset of exercise Biochemical Society Transactions. VOL 30(PART 2), 275-279 ROBERTS, P. A., LOXHAM, S. J. G., POUCHER, S. M., CONSTANTIN-TEODOSIU, D. and GREENHAFF, P. L., 2002. Bicarbonate-induced alkalosis augments cellular acetyl group availability and isometric force during the rest-to-work transition in canine skeletal muscle Experimental Physiology. VOL 87(PART 4), 489-498
ROBERTS, P. A., LOXHAM, S. J. G., POUCHER, S. M., CONSTANTIN-TEODOSIU, D. and GREENHAFF, P. L., 2002. The temporal relationship between glycogen phosphorylase and activation of the pyruvate dehydrogenase complex during adrenaline infusion in resting canine skeletal muscle Journal of Physiology. VOL 545(PART 1), 297-304 GIBALA, M. J., PEIRCE, N., CONSTANTIN-TEODOSIU, D. and GREENHAFF, P. L., 2002. Exercise with low muscle glycogen augments TCA cycle anaplerosis but impairs oxidative energy provision in humans Journal of Physiology. VOL 540(PART 3), 1079-1086 GRASSI, B., HOGAN, M. C., GREENHAFF, P. L., HAMANN, J. J., KELLEY, K. M., ASCHENBACH, W. G., CONSTANTIN-TEODOSIU, D. and GLADDEN, L. B., 2002. Oxygen uptake on-kinetics in dog gastrocnemius in situ following activation of pyruvate dehydrogenase by dichloroacetate Journal of Physiology. VOL 538(PART 1), 195-208 ROBERTS, PA, LOXHAM, SJG, POUCHER, SM, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, 2002. The Temporal Relationship Between Glycogen Phosphorylase And Activation Of The Pyruvate Dehydrogenase Complex During Adrenaline Infusion In Resting Canine Skeletal Muscle Journal Of Physiology-London. 545(1), 297-304 ROBERTS, PA, LOXHAM, SJG, POUCHER, SM, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, 2002. The Acetyl Group Deficit At The Onset Of Contraction In Ischaemic Canine Skeletal Muscle Journal Of Physiology-London. 544(2), 591-602 CONSTANTIN-TEODOSIU, D, YOUNG, S, WELLOCK, F, SHORT, AH, BURDEN, RP, MORGAN, AG and GREENHAFF, PL, 2002. Gender And Age Differences In Plasma Carnitine, Muscle Strength, And Exercise Tolerance In Haemodialysis Patients Nephrology Dialysis Transplantation. 17(10), 1808-1813 ROBERTS, PA, LOXHAM, SJG, POUCHER, SM, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, 2002. Bicarbonate-Induced Alkalosis Augments Cellular Acetyl Group Availability And Isometric Force During The Rest-To-Work Transition In Canine Skeletal Muscle Experimental Physiology. 87(4), 489-498
GIBALA, MJ, PEIRCE, N, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, 2002. Exercise With Low Muscle Glycogen Augments Tca Cycle Anaplerosis But Impairs Oxidative Energy Provision In Humans Journal Of Physiology-London. 540(3), 1079-1086 GREENHAFF, PL, CAMPBELL-O'SULLIVAN, SP, CONSTANTIN-TEODOSIU, D, POUCHER, SM, ROBERTS, PA and TIMMONS, JA, 2002. An Acetyl Group Deficit Limits Mitochondrial Atp Production At The Onset Of Exercise
GRASSI, B, HOGAN, MC, GREENHAFF, PL, HAMANN, JJ, KELLEY, KM, ASCHENBACH, WG, CONSTANTIN-TEODOSIU, D and GLADDEN, LB, 2002. Oxygen Uptake On-Kinetics In Dog Gastrocnemius In Situ Following Activation Of Pyruvate Dehydrogenase By Dichloroacetate Journal Of Physiology-London. 538(1), 195-207 VAN LOON, L. J. C., GREENHAFF, P. L., CONSTANTIN-TEODOSIU, D., SARIS, W. H. M. and WAGENMAKERS, A. J. M., 2001. The effects of increasing exercise intensity on muscle fuel utilisation in humans Journal of Physiology. VOL 536(PART 1), 295-304 BRUCE, M., CONSTANTIN-TEODOSIU, D., GREENHAFF, P. L., BOOBIS, L. H., WILLIAMS, C. and BOWTELL, J. L., 2001. Glutamine supplementation promotes anaplerosis but not oxidative energy delivery in human skeletal muscle American Journal of Physiology. VOL 280(ISSU 4), E669-E675
TSINTZAS, K, WILLIAMS, C, CONSTANTIN-TEODOSIU, D, HULTMAN, E, BOOBIS, L, CLARYS, P and GREENHAFF, P, 2001. Phosphocreatine degradation in type I and type II muscle fibres during submaximal exercise in man: effect of carbohydrate ingestion. Journal of Physiology. 537(Pt 1), 305-11 TSINTZAS, K, WILLIAMS, C, CONSTANTIN-TEODOSIU, D, HULTMAN, E, BOOBIS, L, CLARYS, P and GREENHAFF, P, 2001. Phosphocreatine Degradation In Type I And Type Ii Muscle Fibres During Submaximal Exercise In Man: Effect Of Carbohydrate Ingestion Journal Of Physiology-London. 537(1), 305-311 BRUCE, M, CONSTANTIN-TEODOSIU, D, GREENHAFF, PL, BOOBIS, LH, WILLIAMS, C and BOWTELL, JL, 2001. Glutamine Supplementation Promotes Anaplerosis But Not Oxidative Energy Delivery In Human Skeletal Muscle American Journal Of Physiology-Endocrinology And Metabolism. 280(4), E669-E675
TSINTZAS, K, WILLIAMS, C, CONSTANTIN-TEODOSIU, D, HULTMAN, E, BOOBIS, L and GREENHAFF, P, 2000. Carbohydrate ingestion prior to exercise augments the exercise-induced activation of the pyruvate dehydrogenase complex in human skeletal muscle. Experimental Physiology. 85(5), 581-6 TSINTZAS, K, WILLIAMS, C, CONSTANTIN-TEODOSIU, D, HULTMAN, E, BOOBIS, L and GREENHAFF, P, 2000. Carbohydrate Ingestion Prior To Exercise Augments The Exercise-Induced Activation Of The Pyruvate Dehydrogenase Complex In Human Skeletal Muscle Experimental Physiology. 85(5), 581-586 CONSTANTIN-TEODOSIU, D. and GREENHAFF, P. L., 1999. The tricarboxylic acid cycle in human skeletal muscle: Is there a role for nutritional intervention? Current Opinion in Clinical Nutrition and Metabolic Care. VOL 2(NUMB 6), 527-532 CONSTANTIN-TEODOSIU, D., SIMPSON, E. J. and GREENHAFF, P. L., 1999. The importance of pyruvate availability to PDC activation and anaplerosis in human skeletal muscle American Journal of Physiology. VOL 276(ISSUE 3), E472-E478
CONSTANTIN-TEODOSIU, D, SIMPSON, EJ and GREENHAFF, PL, 1999. The Importance Of Pyruvate Availability To Pdc Activation And Anaplerosis In Human Skeletal Muscle American Journal Of Physiology-Endocrinology And Metabolism. 276(3), E472-E478
RANDALL, M D, KEON, C A, GREENHAFF, P L and CONSTANTIN-TEODOSIU, D, 1998. Dual effects of dichloroacetate on cardiac ischaemic preconditioning in the rat isolated perfused heart. British Journal of Pharmacology. 124(1), 245-51 TIMMONS, J. A., GUSTAFSSON, T., SUNDBERG, C. J., JANSSON, E., HULTMAN, E., KAIJSER, L., CHWALBINSKA-MONETA, J., CONSTANTIN-TEODOSIU, D., MACDONALD, I. A. and GREENHAFF, P. L., 1998. Substrate Availability Limits Human Skeletal Muscle Oxidative ATP Regeneration at the Onset of Ischemic Exercise Journal of Clinical Investigation. VOL 101(NUMBER 1), 79-85 TIMMONS, J. A., POUCHER, S. M., CONSTANTIN-TEODOSIU, D., MACDONALD, I. A. and GREENHAFF, P. L., 1998. Regulation of skeletal muscle carbohydrate oxidation during steady-state contraction American Journal of Physiology. VOL 274(ISSUE 5), R1384-R1389
RANDALL, MD, KEON, CA, GREENHAFF, PL and CONSTANTIN-TEODOSIU, D, 1998. Dual Effects Of Dichloroacetate On Cardiac Ischaemic Preconditioning In The Rat Isolated Perfused Heart British Journal Of Pharmacology. 124(1), 245-251 TIMMONS, JA, POUCHER, SM, CONSTANTIN-TEODOSIU, D, MACDONALD, IA and GREENHAFF, PL, 1998. Regulation Of Skeletal Muscle Carbohydrate Oxidation During Steady-State Contraction American Journal Of Physiology-Regulatory Integrative And Comparative Physiology. 274(5), R1384-R1389
TIMMONS, JA, GUSTAFSSON, T, SUNDBERG, CJ, JANSSON, E, HULTMAN, E, KAIJSER, L, CHWALBINSKA-MONETA, J, CONSTANTIN-TEODOSIU, D, MACDONALD, IA and GREENHAFF, PL, 1998. Substrate Availability Limits Human Skeletal Muscle Oxidative Atp Regeneration At The Onset Of Ischemic Exercise Journal Of Clinical Investigation. 101(1), 79-85 TIMMONS, J. A., POUCHER, S. M., CONSTANTIN-TEODOSIU, D., MACDONALD, I. A. and GREENHAFF, P. L., 1997. Metabolic responses from rest to steady state determine contractile function in ischemic skeletal muscle American Journal of Physiology. VOL 273(ISSUE 2), E233-E238
STROUD, M. A., RITZ, P., COWARD, W. A., SAWYER, M. B., CONSTANTIN-TEODOSIU, D., GREENHAFF, P. L. and MACDONALD, I. A., 1997. Energy expenditure using isotope-labelled water (^2H~2^1^8O), exercise performance, skeletal muscle enzyme activities and plasma biochemical parameters in humans during 95 days of endurance exercise with inadequate energy intake European Journal of Applied Physiology and Occupational Physiology. VOL 76(NUMBER 3), 243-252 CONSTANTIN-TEODOSIU, D., GREENHAFF, P. L., MCINTYRE, D. B., ROUND, J. M. and JONES, D. A., 1997. Anaerobic energy production in human skeletal muscle in intense contraction: a comparison of ^3^1P magnetic resonance spectroscopy and biochemical techniques Experimental Physiology. VOL 82(NUMBER 3), 593-602
CASEY, A., CONSTANTIN-TEODOSIU, D., HOWELL, S., HULTMAN, E. and GREENHAFF, P. L., 1996. Metabolic response of type I and II muscle fibers during repeated bouts of maximal exercise in humans American Journal of Physiology. VOL 271(ISSUE 1), E38-E43
TIMMONS, J A, POUCHER, S M, CONSTANTIN-TEODOSIU, D, WORRALL, V, MACDONALD, I A and GREENHAFF, P L, 1996. Metabolic responses of canine gracilis muscle during contraction with partial ischemia. American Journal of Physiology. 270(3 Pt 1), E400-6
CONSTANTIN-TEODOSIU, D., HOWELL, S. and GREENHAFF, P. L., 1996. Carnitine metabolism in human muscle fiber types during submaximal dynamic exercise Journal of Applied Physiology. VOL 80(NUMBER 3), 1061-1064
CONSTANTIN-TEODOSIU, D., KIRBY, D. P. J., SHORT, A. H., BURDEN, R. P., MORGAN, A. G. and GREENHAFF, P. L., 1996. Free and esterified carnitine in continuous ambulatory peritoneal dialysis patients Kidney International. VOL 49(NUMBER 1), 158-162 CASEY, A., CONSTANTIN-TEODOSIU, D., HOWELL, S., HULTMAN, E. and GREENHAFF, P. L., 1996. Creatine ingestion favorably affects performance and muscle metabolism during maximal exercise in humans American Journal of Physiology. VOL 271(ISSUE 1), E31-E37
CONSTANTIN-TEODOSIU, D, CASEY, A, SHORT, A H, HULTMAN, E and GREENHAFF, P L, 1996. The effect of repeated muscle biopsy sampling on ATP and glycogen resynthesis following exercise in man. European Journal of Applied Physiology and Occupational Physiology. 73(1-2), 186-90 TIMMONS, J A, POUCHER, S M, CONSTANTIN-TEODOSIU, D, WORRALL, V, MACDONALD, I A and GREENHAFF, P L, 1996. Increased acetyl group availability enhances contractile function of canine skeletal muscle during ischemia. Journal of Clinical Investigation. 97(3), 879-83 SHARMA, R., CONSTANTIN-TEDOSIU, D., MIDDLETON, B., WILLIS, M. and PRATTEN, M. K., 1996. Teratogenic potential of free radicals and hexokinase isoenzymes in the postimplantational 'diabetic' rat conceptus Biochemical Society Transactions. VOL 24(NUMBER 2), 235S
CONSTANTIN-TEODOSIU, D, GREENHAFF, P L, GARDINER, S M, RANDALL, M D, MARCH, J E and BENNETT, T, 1995. Attenuation by creatine of myocardial metabolic stress in Brattleboro rats caused by chronic inhibition of nitric oxide synthase. British Journal of Pharmacology. 116(8), 3288-92
CONSTANTIN-TEODOSIU, D., CEDERBLAD, G. and HULTMAN, E., 1993. PDC activity and acetyl group accumulation in skeletal muscle during isometric contraction Journal of Applied Physiology. VOL 74(NUMBER 4), 1712
WIBOM, R, HULTMAN, E, JOHANSSON, M, MATHEREI, K, CONSTANTIN-TEODOSIU, D and SCHANTZ, P G, 1992. Adaptation of mitochondrial ATP production in human skeletal muscle to endurance training and detraining. Journal of Applied Physiology. 73(5), 2004-10
CONSTANTIN-TEODOSIU, D., CEDERBLAD, G. and HULTMAN, E., 1992. PDC activity and acetyl group accumulation in skeletal muscle during prolonged exercise Journal of Applied Physiology. VOL 73(NUMBER 6), 2403
CONSTANTIN-TEODOSIU, D, CEDERBLAD, G and HULTMAN, E, 1991. A sensitive radioisotopic assay of pyruvate dehydrogenase complex in human muscle tissue. Analytical Biochemistry. 198(2), 347-51 CONSTANTIN-TEODOSIU, D, CARLIN, J I, CEDERBLAD, G, HARRIS, R C and HULTMAN, E, 1991. Acetyl group accumulation and pyruvate dehydrogenase activity in human muscle during incremental exercise. Acta Physiologica Scandinavica. 143(4), 367-72 CARLIN, J I, HARRIS, R C, CEDERBLAD, G, CONSTANTIN-TEODOSIU, D, SNOW, D H and HULTMAN, E, 1990. Association between muscle acetyl-CoA and acetylcarnitine levels in the exercising horse. Journal of Applied Physiology. 69(1), 42-5
CEDERBLAD, G, CARLIN, J I, CONSTANTIN-TEODOSIU, D, HARPER, P and HULTMAN, E, 1990. Radioisotopic assays of CoASH and carnitine and their acetylated forms in human skeletal muscle. Analytical Biochemistry. 185(2), 274-8 STEPHENS, FB, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, A central role for carnitine in the in vivo regulation of fuel metabolism in skeletal muscle In: LX-LX
CONSTANTIN-TEODOSIU, D, BAKER, DJ, TIMMONS, JA and GREENHAFF, PL, Clenbuterol pro-drug (BRL-47672) administration reduces mitochondrial density and fat oxidation in rat soleus muscle In: 26P-27P
ROBERTS, PA, LOXHAM, SJG, POUCHER, SM, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, The temporal relationship between glycogen phosphorylase and pyruvate dehydrogenase complex activation following adrenaline infusion in resting canine skeletal muscle In: 48P-48P
BRUCE, M, CONSTANTIN-TEODOSIU, D, GREENHAFF, PL, BOOBIS, LH, WILLIAMS, C and BOWTELL, JL, Effect of glutamine and ornithine alpha-ketoglutarate supplementation on tricarboxylic acid cycle intermediate (TCAI) pool size In: A92-A92
VAN LOON, LJC, GREENHAFF, PL, CONSTANTIN-TEODOSIU, D, SARIS, WHM and WAGENMAKERS, AJM, The effects of increasing exercise intensity on fuel selection; Free carnitine a key regulator. In: A429-A429
CONSTANTIN-TEODOSIU, D, TSINTZAS, K, WILLIAMS, C, BOOBIS, L, HULTMAN, E and GREENHAFF, PL, Carnitine metabolism in human muscle fibre types at the onset of sub-maximal exercise In: 226P-227P
CAMPBELL, SP, HULTMAN, E, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, Acetyl group delivery limits mitochondrial flux in human skeletal muscle In: 227P-228P
ROBERTS, PA, LOXHAM, SJG, POUCHER, SM, CONSTANTIN-TEODOSIU, D and GREENHAFF, PL, The acetyl group deficit at the onset of contraction in canine skeletal muscle In: 228P-229P
RAJAB, P, CONSTANTIN-TEODOSIU, D, MAYER, RJ, GARDINER, SM, BENNETT, T and GREENHAFF, PL, Increase in proteasome activity 6 h after a single bolus administration of the beta(2)-adrenoceptor agonist clenbuterol in conscious rats In: U19-U19
TSINTZAS, K, WILLIAMS, C, CONSTANTIN-TEODOSIU, D, HULTMAN, E, BOOBIS, L and GREENHAFF, P, Dual effect of carbohydrate feeding on skeletal muscle substrate utilization during exercise in man In: 101P-101P
CONSTANTIN-TEODOSIU, D, SIMPSON, EJ and GREENHAFF, PL, Effects of pyruvate, dichloroacetate and adrenaline infusion on pyruvate dehydrogenase complex activation and tricarboxylic acid cycle intermediates in human skeletal muscle In: 102P-102P