Central nervous system disorders
The Importance of Research in Disorders of the Central Nervous System
Disorders of the central nervous system (CNS), such as Attention Deficit Hyperactivity Disorder, obesity, schizophrenia, stroke and depression are becoming increasingly prevalent in society. Current drug treatments target the symptoms but not the underlying causes of these diseases. The CNS disorders group is involved in the development and evaluation of animal models to understand disease processes and provide reliable test beds for developing new treatments.
Our Research Interests in Disorders of the Central Nervous System
We use a range of experimental techniques, including behavioural analysis, immunohistochemistry, radiotelemetry, metabolic cages, microdialysis, electrophysiology, molecular biology, epigenetics and MRI. These allow us to identify changes within neurones and astrocytes in the brain that underlie alterations in behaviour and physiology of the whole animal. The group has collaborative support from several pharmaceutical companies as well as research councils and charities and offers excellent training facilities for young scientists.
For more information, please email Professor Kevin Fone .
See research degree opportunities related to this group .
Group Publications
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- Front Behav Neurosci; Toledo-Rodriguez, M. and Sandi, C.
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- Behav Neurosci; Valencia Torres, L., Olarte Sanchez, C.M., Body, S., Fone, K.C., Bradshaw, C.M., and Szabadi, E.
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- Dis Model Mech; Machuca-Tzili, L.E., Buxton, S., Thorpe, A., Timson, C.M., Wigmore, P., Luther, P.K., and Brook, J.D.
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- Neuropharmacology; Marsden, C.A., King, M.V., and Fone, K.C.
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- PLoS One; Lyons, L., Elbeltagy, M., Bennett, G., and Wigmore, P.
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- Psychopharmacology (Berl); Lyons, L., Elbeltagy, M., Umka, J., Markwick, R., Startin, C., Bennett, G., and Wigmore, P.