Molecular signalling
Importance of Research in Molecular Signalling
Just as humans populate the world in which we live, inside each cell there is a world populated with proteins. Like us, proteins are born, they have specific jobs to do and ultimately they die and get replaced. Proteins are also social, they work in interactive groups; they are efficient at what they do and part of the reason is that they communicate with each other, directly and indirectly.
Our Research Interests in Molecular Signalling
The ability of proteins to interact and communicate is the basis of molecular signalling. It is going on all the time in and between all the cells of our bodies and we take it completely for granted – until something goes wrong. Cancer is a good example of molecular signalling gone wrong, but equally, aberrant molecular signalling underlies the development of hereditary and degenerative diseases, such as Paget’s disease of bone, rheumatoid arthritis and Parkinson’s disease. Our work is aimed at understanding the fundamentals of molecular signalling so we, and others, can develop strategies to correct things when they go wrong.
For more information, please email Professor Peter Shaw .
See research degree opportunities related to this group.
Group Publications
- Description
- Cell Biol Int; Wheatley, S.P.
- Description
- FEBS Lett; Foxler, D.E., James, V., Shelton, S.J., Vallim, T.Q., Shaw, P.E., and Sharp, T.V.
- Description
- Biochemistry; Garner, T.P., Long, J., Layfield, R., and Searle, M.S.
- Description
- J Clin Invest; Connell, C.M., Shibata, A., Tookman, L.A., Archibald, K.M., Flak, M.B., Pirlo, K.J., Lockley, M., Wheatley, S.P., and McNeish, I.A.
- Description
- Hum Mol Genet; Daroszewska, A., van 't Hof, R.J., Rojas, J.A., Layfield, R., Landao-Basonga, E., Rose, L., Rose, K., and Ralston, S.H.