Faculty of Engineering
 

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Kevin Webb

Associate Professor in Applied Optics and Electrophysiology, Faculty of Engineering

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Biography

Dr Kevin Webb is an Associate Professor in Applied Optics and Electrophysiology, in the Optics & Photonics Group of the School of Electrical & Electronic Engineering. Kevin trained at the University of Auckland, New Zealand as an electrophysiologist, patch clamping differentiated fibre cells from the ocular lens - a unique tissue which is itself an optical component. Following a post-doc at University College London working on cell differentiation in the retina, he joined the Institute of Biophysics, Imaging & Optical Science at The University of Nottinghamin February 2008, applying surface plasmon imaging and electrophysiology to cultures of primary hippocampal neurons. Kevin was awarded a Royal Academy of Engineering/EPSRC Fellowship in 2010 to apply novel imaging and electrophysiological methods to the retina. His current work is using the retinal pigment epithelium as a model system to examine epithelial fluid transport in transparent ocular tissues using a combination of scanning probe microscopy, electrophysiology, and Raman microspectroscopy.

Dr Webb is a member of the Optics and Photonics research group.

Expertise Summary

"A day in the life"

Teaching Summary

Undergraduate courses:

  • EEEE3089 - Sensing Systems and Signal Processing (co-convenor)
  • LIFE3001: Cellular and Molecular Neuroscience
  • LIFE3070 Translational Neuroimaging

Convenor: EEEE3001 - Third year Project (3rd year, 30 credits, BEng) EEEE4008 - Industrial/Research Orientated Project (4th year, 40 credits, MEng)

Interdisciplinary MSc and final year Projects supervised in EEE, Neuroscience, Biomedical Science

Research Summary

Kevin has an abiding interest in the physiology of transparent tissues of the eye: in particular the cornea, retina, and ocular lens. He was the first to isolate and functionally characterise in… read more

Selected Publications

Current Research

Kevin has an abiding interest in the physiology of transparent tissues of the eye: in particular the cornea, retina, and ocular lens. He was the first to isolate and functionally characterise in vitro the terminally differentiated fibre cells which form the bulk of the ocular lens. His work confirmed at the cellular level the electrophysiological and ion transporting properties of these specialised cells and their role within the connected syncytium which is the ocular lens. Kevin applies novel high resolution imaging and electrophysiological methods to the study of epithelial transport, using model systems which include the cornea, retinal pigment epithelium, lung, and gut. Among the techniques used are confocal laser scanning microscopy, immunofluorescence, optogenetics, scanning ion conductance microscopy, Raman microspectroscopy, and epithelial voltage clamp. Kevin's current work is funded by the BBSRC, entitled "Direct imaging of epithelial fluid transport at the subcellular scale", the Leverhulme Trust ("Watching Plants Drink"), and the US National Science Foundation ("Commercialisation of nanoporous SERS biosensors")

Faculty of Engineering

The University of Nottingham
University Park
Nottingham, NG7 2RD



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