Clinical Physiology

The Clinical Physiology Group is a world leader in the multi aspects of skeletal muscle and muscle protein functioning and degradation.  The group is currently researching into: 

• The evolution of hominid dietary adaptations linked with environmental changes: extending the record beyond 100,000 years. A thematic proposal in the NERC EFCHED programme (NERC)
• Alterations in human bone collagen synthesis and osteoblast gene expression after femoral fractures: acute and longer term changes and the effect of growth hormone (AO foundation, Switzerland)
• Sexual dimorphism, adiposity and muscle protein metabolism (US NIH).
• Overcoming the blunted response to food to maximize muscle maintenance in the elderly (BBSRC)
• Equipment to measure leg blood flow and tissue amino acids in determining the molecular basis of nutrient sensitivity of human muscle protein turnover  (BBSRC REI)
• Do amino acids have specific anabolic effects on human bone collagen synthesis ? (Ajinomoto Inc)
• Immobilization-induced changes in skeletal muscle protein turnover in the fed state (Canadian NIH)
• Health benefits of exercise: identification of genes and signalling pathways involved in effects of exercise on insulin resistance, obesity and the metabolic syndrome (EU)
• The networked control of muscle protein degradation
• Biological alterations in response to space flight