Stopping breast cancer spreading
You can save lives by helping us to find new ways to stop breast cancer from spreading
Breast cancer kills - particularly when it spreads outside the breast and grows around the body – a process called metastasis. Dr Stewart Martin and colleagues - crowned Breast Cancer Campaign Research Team of the Year in 2013 - are investigating how to stop this process in its tracks.
Along with world-renowned researcher Professor Ian Ellis, Dr Martin and team discovered that breast cancer cells use the lymphatic system to travel and spread. They have pinpointed particular proteins that are linked to this process and found that these proteins can also make cancer cells resistant to treatment.
They are now using these insights to develop new techniques that will help make conventional treatments more effective – giving hope to women around the world.
Novel drugs developed right here in Nottingham
Dr Martin has shown that screening for key proteins can help identify patients at high risk of metastasis and also indicate a woman’s likeliness to respond to conventional therapies. This information can guide which therapy should be offered to patients, with the aim of making sure every woman has the most effective treatment for their cancer type.
The team are now working with colleagues from the School of Chemistry and testing new drugs, developed here in Nottingham, that specifically target the proteins to make cells more responsive to treatment - offering hope to all those with breast cancers that are currently resistant to conventional therapies.
They are also continuing the hunt for additional proteins that regulate the process of metastasis. Professor Ellis and colleague Emad Rakha, are conducting large-scale analyses working in collaboration with other national and international groups.
You can make a difference by giving a gift
From biking and baking to organising your own fundraising event or challenge – there are lots of great ways to support this research through Life Cycle 6 - our annual fundraising campaign.
Love cycling? Join us here in Nottingham for our sponsored family-friendly bike ride on Sunday 4th September. Choose your challenge with routes from 10 to 75 miles.
"100% of every penny
raised will go direct to
this life-saving research"
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