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David Archer

Emeritus Professor,

Personal Details
Research
Publications

Contact

workLife Sciences
University Park
Nottingham
NG7 2RD
UK
work0115 951 3313
david.archer@nottingham.ac.uk

Biography

M.A., Ph.D. Cambridge

Post-doctoral research: Cambridge University, CSIRO Melbourne (Royal Society Florey Fellow), John Innes Institute, Norwich.

Institute of Food Research, Noriwch, University of Nottingham (from 2000)

Expertise Summary

Filamentous fungi, yeasts, biochemistry, molecular biology, biotechnology.

Research Summary

Recent Publications

DE VRIES RP, RILEY R, WIEBENGA A, AGUILAR-OSORIO G, AMILLIS S, UCHIMA CA, ANDERLUH G, ASADOLLAHI M, ASKIN M, BARRY K, BATTAGLIA E, BAYRAM Ö, BENOCCI T, BRAUS-STROMEYER SA, CALDANA C, CÁNOVAS D, CERQUEIRA GC, CHEN F, CHEN W, CHOI C, CLUM A, DOS SANTOS RA, DAMÁSIO AR, DIALLINAS G, EMRI T, FEKETE E, FLIPPHI M, FREYBERG S, GALLO A, GOURNAS C, HABGOOD R, HAINAUT M, HARISPE ML, HENRISSAT B, HILDÉN KS, HOPE R, HOSSAIN A, KARABIKA E, KARAFFA L, KARÁNYI Z, KRAŠEVEC N, KUO A, KUSCH H, LABUTTI K, LAGENDIJK EL, LAPIDUS A, LEVASSEUR A, LINDQUIST E, LIPZEN A, LOGRIECO AF, MACCABE A, MÄKELÄ MR, MALAVAZI I, MELIN P, MEYER V, MIELNICHUK N, MISKEI M, MOLNÁR ÁP, MULÉ G, NGAN CY, OREJAS M, OROSZ E, OUEDRAOGO JP, OVERKAMP KM, PARK HS, PERRONE G, PIUMI F, PUNT PJ, RAM AF, RAMÓN A, RAUSCHER S, RECORD E, RIAÑO-PACHÓN DM, ROBERT V, RÖHRIG J, RULLER R, SALAMOV A, SALIH NS, SAMSON RA, SÁNDOR E, SANGUINETTI M, SCHÜTZE T, SEPČIĆ K, SHELEST E, SHERLOCK G, SOPHIANOPOULOU V, SQUINA FM, SUN H, SUSCA A, TODD RB, TSANG A, UNKLES SE, VAN DE WIELE N, VAN ROSSEN-UFFINK D, OLIVEIRA JV, VESTH TC, VISSER J, YU JH, ZHOU M, ANDERSEN MR, ARCHER DB, BAKER SE, BENOIT I, BRAKHAGE AA, BRAUS GH, FISCHER R, FRISVAD JC, GOLDMAN GH, HOUBRAKEN J, OAKLEY B, PÓCSI I, SCAZZOCCHIO C, SEIBOTH B, VANKUYK PA, WORTMAN J, DYER PS and GRIGORIEV IV, 2017. Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus. Genome biology. 18(1), 28
VAN MUNSTER JM, THOMAS B, RIESE M, DAVIS AL, GRAY CJ, ARCHER DB and FLITSCH SL, 2017. Application of carbohydrate arrays coupled with mass spectrometry to detect activity of plant-polysaccharide degradative enzymes from the fungus Aspergillus niger. Scientific reports. 7, 43117
DALY P, VAN MUNSTER JM, BLYTHE MJ, IBBETT R, KOKOLSKI M, GADDIPATI S, LINDQUIST E, SINGAN VR, BARRY KW, LIPZEN A, NGAN CY, PETZOLD CJ, CHAN LJ, PULLAN ST, DELMAS S, WALDRON PR, GRIGORIEV IV, TUCKER GA, SIMMONS BA and ARCHER DB, 2017. Expression of Aspergillus niger CAZymes is determined by compositional changes in wheat straw generated by hydrothermal or ionic liquid pretreatments. Biotechnology for biofuels. 10, 35
NOVODVORSKA, MICHAELA, STRATFORD, MALCOLM, BLYTHE, MARTIN J., WILSON, RAYMOND, BENISTON, RICHARD G. and ARCHER, DAVID B., 2016. Metabolic activity in dormant conidia of Aspergillus niger and developmental changes during conidial outgrowth FUNGAL GENETICS AND BIOLOGY. 94, 23-31

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Current Research

Since retirement in 2015, I continue to pursue research as an Emeritus Professor. My research focus is with filamentous fungi, their development from spores to mycelium, their responses to weak acids, and their ability to degrade lignocellulosic materials. In collaboration with Professor Simon Avery and Dr Malcolm Stratford, I explore the molecular basis of weak acid responses and the phenotypic heterogeneity of fungal cells.

DE VRIES RP, RILEY R, WIEBENGA A, AGUILAR-OSORIO G, AMILLIS S, UCHIMA CA, ANDERLUH G, ASADOLLAHI M, ASKIN M, BARRY K, BATTAGLIA E, BAYRAM Ö, BENOCCI T, BRAUS-STROMEYER SA, CALDANA C, CÁNOVAS D, CERQUEIRA GC, CHEN F, CHEN W, CHOI C, CLUM A, DOS SANTOS RA, DAMÁSIO AR, DIALLINAS G, EMRI T, FEKETE E, FLIPPHI M, FREYBERG S, GALLO A, GOURNAS C, HABGOOD R, HAINAUT M, HARISPE ML, HENRISSAT B, HILDÉN KS, HOPE R, HOSSAIN A, KARABIKA E, KARAFFA L, KARÁNYI Z, KRAŠEVEC N, KUO A, KUSCH H, LABUTTI K, LAGENDIJK EL, LAPIDUS A, LEVASSEUR A, LINDQUIST E, LIPZEN A, LOGRIECO AF, MACCABE A, MÄKELÄ MR, MALAVAZI I, MELIN P, MEYER V, MIELNICHUK N, MISKEI M, MOLNÁR ÁP, MULÉ G, NGAN CY, OREJAS M, OROSZ E, OUEDRAOGO JP, OVERKAMP KM, PARK HS, PERRONE G, PIUMI F, PUNT PJ, RAM AF, RAMÓN A, RAUSCHER S, RECORD E, RIAÑO-PACHÓN DM, ROBERT V, RÖHRIG J, RULLER R, SALAMOV A, SALIH NS, SAMSON RA, SÁNDOR E, SANGUINETTI M, SCHÜTZE T, SEPČIĆ K, SHELEST E, SHERLOCK G, SOPHIANOPOULOU V, SQUINA FM, SUN H, SUSCA A, TODD RB, TSANG A, UNKLES SE, VAN DE WIELE N, VAN ROSSEN-UFFINK D, OLIVEIRA JV, VESTH TC, VISSER J, YU JH, ZHOU M, ANDERSEN MR, ARCHER DB, BAKER SE, BENOIT I, BRAKHAGE AA, BRAUS GH, FISCHER R, FRISVAD JC, GOLDMAN GH, HOUBRAKEN J, OAKLEY B, PÓCSI I, SCAZZOCCHIO C, SEIBOTH B, VANKUYK PA, WORTMAN J, DYER PS and GRIGORIEV IV, 2017. Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus. Genome biology. 18(1), 28
VAN MUNSTER JM, THOMAS B, RIESE M, DAVIS AL, GRAY CJ, ARCHER DB and FLITSCH SL, 2017. Application of carbohydrate arrays coupled with mass spectrometry to detect activity of plant-polysaccharide degradative enzymes from the fungus Aspergillus niger. Scientific reports. 7, 43117
DALY P, VAN MUNSTER JM, BLYTHE MJ, IBBETT R, KOKOLSKI M, GADDIPATI S, LINDQUIST E, SINGAN VR, BARRY KW, LIPZEN A, NGAN CY, PETZOLD CJ, CHAN LJ, PULLAN ST, DELMAS S, WALDRON PR, GRIGORIEV IV, TUCKER GA, SIMMONS BA and ARCHER DB, 2017. Expression of Aspergillus niger CAZymes is determined by compositional changes in wheat straw generated by hydrothermal or ionic liquid pretreatments. Biotechnology for biofuels. 10, 35
NOVODVORSKA, MICHAELA, STRATFORD, MALCOLM, BLYTHE, MARTIN J., WILSON, RAYMOND, BENISTON, RICHARD G. and ARCHER, DAVID B., 2016. Metabolic activity in dormant conidia of Aspergillus niger and developmental changes during conidial outgrowth FUNGAL GENETICS AND BIOLOGY. 94, 23-31
RAULO, ROXANE, KOKOLSKI, MATTHEW and ARCHER, DAVID B., 2016. The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger AMB EXPRESS. 6,
DALY P, VAN MUNSTER JM, KOKOLSKI M, SANG F, BLYTHE MJ, MALLA S, VELASCO DE CASTRO OLIVEIRA J, GOLDMAN GH and ARCHER DB, 2016. Transcriptomic responses of mixed cultures of ascomycete fungi to lignocellulose using dual RNA-seq reveal inter-species antagonism and limited beneficial effects on CAZyme expression. Fungal genetics and biology : FG & B. (In Press.)
RAULO R, KOKOLSKI M and ARCHER DB, 2016. The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger. AMB Express. 6(1), 5
PULLAN ST, DALY P, DELMAS S, IBBETT R, KOKOLSKI M, NEITELER A, VAN MUNSTER JM, WILSON R, BLYTHE MJ, GADDIPATI S, TUCKER GA and ARCHER DB, 2015. RNA-sequencing reveals the complexities of the transcriptional response to lignocellulosic biofuel substrates in Aspergillus niger. Fungal biology and biotechnology. 1(1), 1-14
STRATFORD, MALCOLM, STEELS, HAZEL, NEBE-VON-CARON, GERHARD, AVERY, SIMON V., NOVODVORSKA, MICHAELA and ARCHER, DAVID B., 2014. Population heterogeneity and dynamics in starter culture and lag phase adaptation of the spoilage yeast Zygosaccharomyces bailii to weak acid preservatives International Journal of Food Microbiology. 181, 40-47
VAN MUNSTER, JOLANDA M., DALY, PAUL, DELMAS, STEPHANE, PULLAN, STEVEN T., BLYTHE, MARTIN J., MALLA, SUNIR, KOKOLSKI, MATTHEW, NOLTORP, EMELIE C. M., WENNBERG, KRISTIN, FETHERSTON, RICHARD, BENISTON, RICHARD, YU, XIAOLAN, DUPREE, PAUL and ARCHER, DAVID B., 2014. The role of carbon starvation in the induction of enzymes that degrade plant-derived carbohydrates in Aspergillus niger FUNGAL GENETICS AND BIOLOGY. 72, 34-47
RIES L, BELSHAW NJ, ILMÉN M, PENTTILÄ ME, ALAPURANEN M and ARCHER DB, 2014. The role of CRE1 in nucleosome positioning within the cbh1 promoter and coding regions of Trichoderma reesei. Applied microbiology and biotechnology. 98(2), 749-62
HAYER K, STRATFORD M and ARCHER DB, 2014. Germination of Aspergillus niger conidia is triggered by nitrogen compounds related to L-amino acids. Applied and environmental microbiology. 80(19), 6046-53
HILDEN, KRISTIINA, MAKELA, MIIA R., STEFFEN, KARI T., HOFRICHTER, MARTIN, HATAKKA, ANNELE, ARCHER, DAVID B. and LUNDELL, TAINA K., 2014. Biochemical and molecular characterization of an atypical manganese peroxidase of the litter-decomposing fungus Agrocybe praecox FUNGAL GENETICS AND BIOLOGY. 72, 131-136
DELMAS, STEPHANE, LLANOS, AGUSTINA, PARROU, JEAN-LUC, KOKOLSKI, MATTHEW, PULLAN, STEVEN T., SHUNBURNE, LEE and ARCHER, DAVID B., 2014. Development of an Unmarked Gene Deletion System for the Filamentous Fungi Aspergillus niger and Talaromyces versatilis APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 80(11), 3484-3487
RIES, L., BELSHAW, N. J., ILMEN, M., PENTTILA, M. E., ALAPURANEN, M. and ARCHER, D. B., 2014. The role of CRE1 in nucleosome positioning within the cbh1 promoter and coding regions of Trichoderma reesei APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 98(2), 749-762