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Elizabeth Rosethorne

Senior Research Fellow, Faculty of Medicine & Health Sciences

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Biography

Elizabeth Rosethorne graduated from the University of Manchester with a BSc (hons) in Biomedical Sciences with Industrial Experience and went on to do a PhD in the department of Cell Physiology & Pharmacology at the University of Leicester (PhD 2007; GPCR regulation of CREB and the amyloid precursor protein). After this she moved to the Novartis Institutes for Biomedical Research where she was an Investigator (2007 - 2014). Here she managed a small team whose research focused on primary human cell biology and High Content Imaging, and acted as Project team leader for a multi-site respiratory disease drug discovery project in IPF. Her particular expertise aimed at understanding cAMP signalling and the use of phenotypic assays for compound screening. She then moved to the University of Nottingham as a Senior Research Fellow in the School of Life Sciences, working in the area of Molecular Pharmacology & Drug Discovery. Her current research interests involve the use of phenotypic assays to identify novel targets for disease and the differentiation between ligand, system and observational bias on a cell and molecular level.

Elizabeth is the author of > 15 peer-reviewed publications, has delivered lectures at UK and European academic departments and has presented her work at internationally renowned Scientific Conferences. She is actively involved in the peer review and editing process for a number of scientific journals.

Research Summary

My research interests lie in the use of phenotypic assays to identify novel targets for disease and give us insights into the mechanism of action of drugs. I am also interested in learning more about… read more

Recent Publications

Current Research

My research interests lie in the use of phenotypic assays to identify novel targets for disease and give us insights into the mechanism of action of drugs. I am also interested in learning more about the role of biased signalling in GPCR pharmacology by using different techniques to differentiate between system and observational bias on a cell and molecular level.

School of Life Sciences

University of Nottingham
Medical School
Queen's Medical Centre
Nottingham NG7 2UH

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