School of Life Sciences
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Simon Dawson

Lecturer in Biochemistry, Faculty of Medicine & Health Sciences

Contact

  • workRoom D76 (within D75) University of Nottingham Medical School
    Queen's Medical Centre
    Nottingham
    NG7 2UH
    UK
  • work0115 82 30121
  • fax0115 82 30103

Research Summary

Research Interests Research interests include the role of the gankyrin oncoprotein in hepatocellular carcinogenesis; the roll of ubiquitin-protein ligase enzymes (E3s) in cell biology particularly… read more

Recent Publications

Current Research

Research Interests Research interests include the role of the gankyrin oncoprotein in hepatocellular carcinogenesis; the roll of ubiquitin-protein ligase enzymes (E3s) in cell biology particularly the NEDD4-family of E3s within intracellular protein trafficking, signalling and the identification of potential substrates thereof; ubiquitin-like proteins. Techniques • Protein-protein interaction analysis - two-hybrid screening and analysis via 'classical' and SOS/ras yeast and bacterial systems, co-immunoprecipitation, fluorescence microscopy • Cell tissue culture • General molecular biology - PCR, in vitro mutagenesis, cloning etc • Recombinant protein expression via bacterial and Pichia pastoris systems • Reporter gene analysis

School of Life Sciences

University of Nottingham
Medical School
Queen's Medical Centre
Nottingham NG7 2UH

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