School of Life Sciences
  • Print
   
   
 

Vincent Wilson

Associate Professor and Reader in Autonomic Pharmacology, Faculty of Medicine & Health Sciences

Contact

  • workRoom E34b The University of Nottingham Medical School
    Queen's Medical Centre
    Nottingham
    NG7 2UH
    UK
  • work0115 82 30189
  • fax0115 82 30142

Research Summary

Interests

  • The effect of dietary flavonoids and manipulation cellular cholesterol on vascular function
  • Autonomic neurotransmission in vascular and gastrointestinal muscle.
  • Bacterial products and the interaction between immune systems and the vasculature

Techniques

  • Isometric tension recording of large and small blood vessels (wire myography).
  • Radioligand binding and cyclic nucleotide measurements in smooth muscle.
  • Flow cytometry.

Projects

  • The effect of statins and manipulation of cellular cholesterol on smooth muscle, endothelial and nervous functionPharmacological strategies for treating faecal incontinence and haemorrhoids (Norgine and Pfizer, UK)
  • An integrated assessment of the ability of dietary flavonoids to improve vascular function (BBSRC)
  • Steroids and sepsis: Development of an in vitro human model to evaluate the effects of glucocorticoids on vascular reactivity (European Anaesthetic Society).

Centre Collaborators

  • Dr. William Dunn
  • Dr. Ravi Mahajan
  • Dr. Moira Taylor

UK Collaborators

  • Professor John Scholefield (Department of Surgery University of Nottingham).
  • Professor D, Pritchard (School of Pharmaceutical Sciences, University of Nottingham).
  • Dr David Hughes (BBSRC Insitute of Food Research, Colney Lane Norwich)

International Collaborators

  • Dr James Brock (Prince of Wales Medical Research Institute, Sydney, Austraila).

Recent Publications

Future Research

I have a long-standing interest in the pharmacological properties of isolated blood vessels, with particular interest in the factors that influence the functional expression of the receptors negatively-coupled to adenylyl cyclase and the activity of compounds of microbial origin.

School of Life Sciences

University of Nottingham
Medical School
Queen's Medical Centre
Nottingham NG7 2UH

Contact us