School of Life Sciences
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William Dunn

Director, BMedSci. Designated Individual, HTA Research Licence., Faculty of Medicine & Health Sciences

Contact

  • workRoom E34a University of Nottingham Medical School
    Queen's Medical Centre
    Nottingham
    NG7 2UH
    UK
  • work0115 82 30188
  • fax0115 82 30142

Research Summary

Interests

  • The structure and function of human blood vessels in health and disease.
  • Endothelial function in normal pregnancy and in pregnancies complicated by pre-eclampsia.
  • Autonomic neurotransmission in small arteries.

Techniques

  • Pressure myography.
  • Sharp microelectrode recordings of membrane potential.
  • Continuous amperometry for real-time monitoring of noradrenaline release from sympathetic nerves.
  • Light and electron microscopy.

Projects

  • Endothelium function in normal and compromised pregnancies (Wellcome Trust).
  • Sympathetic neurotransmission in the resistance vasculature (Wellcome Trust).
  • Endocannabinoids and nervous function (Royal Society).

Centre Collaborators

  • Prof. Terry Mayhew
  • Dr. Vera Ralevic
  • Dr. Michael Randall
  • Dr. Vincent Wilson

UK Collaborators

  • Professor Phil Baker (University of Manchester).

International Collaborators

  • Dr James Brock (Prince of Wales Medical Research Institute, Sydney, Australia).

Selected Publications

Future Research

Cardiovascular science,pre-eclampsia,hypertension,sympathetic neurotransmission.

School of Life Sciences

University of Nottingham
Medical School
Queen's Medical Centre
Nottingham NG7 2UH

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