Focus: molecular pathogenesis of, and host response to, bacterial infections
The Molecular Bacteriology and Immunology Group (MBIG) consists of an active team of researchers dedicated to the study of molecular mechanisms of the host-pathogen interaction. This includes the dynamics of bacterial infection and the natural history of host defence against bacterial colonisation and invasion.
Our ultimate goal is to define strategies for the prevention and treatment of human bacterial diseases.
Members of MBIG are involved in research programmes on a number of Gram negative and Gram positive bacterial pathogens, including Neisseria meningitidis, Campylobacter jejuni, Staphylococcus aureus, Pseudomonas aeruginosa and Actinobacillus pleuropneumonia.
|Main areas of research||1)
of novel bacterial virulence factors, vaccine candidates and host receptors.
We study their molecular structures, functional attributes and immunological
c) Molecular and cell biology of meningococcal secreted proteins, particularly autotransporter proteins.
2) Human gene expression in response to bacterial infections, using microarrays and other genomic and proteomic tools;
3) Molecular epidemiology and population genetics of community- and hospital-acquired bacteria.
4) Bacterial genome sequencing.
5) Vaccine development against Neisseria meningitidis
|The group has extensive collaborative links with scientists both nationally and internationally. We also accomodate training researchers (Research Fellows and Ph.D students) from UK and all parts of the world.|
|Head of MBIG||Prof.
||Professor of Clinical Microbiology|
Dr Karl Wooldridge
Professor in Molecular Microbiology,
Deputy Head of MBIG
|Dr David Turner||Associate Clinical Professor in Microbiology|
|Prof. Keith Neal||Professor in Public Health|
|Dr Paddy Tighe||Associate Professor in Immunology|
|Chris Bayliss||Lecturer in Molecular Microbiology, Leicester University|
|Scientists||Dr Neil Oldfield||Molecular biologist|
|Dr Jafar Mahdavi||Cell biologist|
|Lee Wheldon||Cell biologist|
|Jeroen Stoof||Molecular Biologist|
|Pierre J Royer||Cell biologist|
|Akhmed Aslam||Protein chemist|
||Hibah Albasri||Saudi Arabia|
|Falwah Al-Qhtany||Saudi Arabia|
and Immunology Group
16 May, 2012