Scientist
Tel: +44 (0)115 8230743
My research has focussed on the host-pathogen interactions human cell biology in meningococcal meningitis.
Selected publications
Royer PJ, Emara M, Yang C, Al-Ghouleh A, Tighe P, Jones N, Sewell HF, Shakib F,
Martinez-Pomares L, Ghaemmaghami AM. The mannose receptor mediates the
uptake of diverse native allergens by dendritic cells and determines allergen-induced
T cell polarization through modulation of indoleamine 2,3-dioxygenase activity. J Immunol. 2010; 185: 1522-1531.
García-Nieto S, Shakesheff KM, Johal RK, Emara E, Royer PJ, Shakib F,
Ghaemmaghami AM. Laminin and Fibronectin Treatment Leads to Generation of
Dendritic Cells with Superior Endocytic Capacity. PLoS ONE. 5(4):e10123.
Remy S, Blancou P, Tesson L, Tardif V, Brion R, Royer PJ, Motterlini R, Foresti R,
Painchaut M, Pogu S, Gregoire M, Bach JM, Anegon I, Chauveau C. Carbon
monoxide inhibits TLR-induced dendritic cell immunogenicity. J Immunol. 2009,
182(4):1877-1884.
Pichard V, Royer PJ, Richou C, Cauchin E, Goebes K, Gaignerie A, Masliah C,
Gournay J, Gregoire M, Ferry N. Detection, isolation, and characterization of alphafetoprotein-
specific T cell populations and clones using MHC class I multimer
magnetic sorting. J Immunother. 2008, 31(3):246-53.
Royer PJ, Bougras G, Ebstein F, Leveque L, Tanguy-Royer S, Simon T, Juge-
Morineau N, Chevallier P, Harousseau JL, Gregoire M. Efficient monocyte-derived
dendritic cell generation in patients with acute myeloid leukemia after chemotherapy
treatment: application to active immunotherapy. Exp Hematol. 2008, 36(3):329-339.
Hill M, Tanguy-Royer S, Royer PJ, Chauveau C, Asghar K, Tesson L, Lavainne F,
Remy S, Brion R, Hubert FX, Heslan M, Rimbert M, Berthelot L, Moffett JR, Josien R,
Gregoire M and Anegon I. Indoleamine 2,3-dioxygenase expands human
CD4+CD25high regulatory T cells by promoting maturation of LPS-treated dendritic
cells. Eur J Immunol. 2007, 37(11):3054-3062.
Royer PJ, Tanguy-Royer S, Ebstein F, Sapede C, Simon T, Barbieux I, Oger R,
Gregoire M. Culture medium and protein supplementation in the generation and
maturation of dendritic cells. Scand J Immunol. 2006, 63(6):401-409.
McIlroy D, Tanguy-Royer S, Le Meur N, Guisle I, Royer PJ, Leger J, Meflah K,
Gregoire M. Profiling dendritic cell maturation with dedicated microarrays. J Leukoc
Biol. 2005, 78(3):794-803.
Chauveau C, Remy S, Royer PJ, Hill M, Tanguy-Royer S, Hubert FX, Tesson L,
Brion R, Beriou G, Gregoire M, Josien R, Cuturi MC, Anegon I. Heme oxygenase-1
expression inhibits dendritic cell maturation and proinflammatory function but
conserves IL-10 expression. Blood. 2005, 106(5):1694-702.
Ebstein F, Sapede C, Royer PJ, Marcq M, Ligeza-Poisson C, Barbieux I, Cellerin L,
Dabouis G, Gregoire M. Cytotoxic T cell responses against mesothelioma by
apoptotic cell-pulsed dendritic cells. Am J Respir Crit Care Med. 2004, 169(12):1322-
30.
Contact details:
Centre for Biomolecular Sciences
University of Nottingham
University Park
Nottingham NG7 2RD
Tel: +44 (0)115 924 9924 ext 42457