Scientist
After reading for a degree in genetics at the University of Leeds (1988-1991)
I undertook a PhD in Plant Molecular Genetics at the University of Nottingham
(1992-1996). There then followed a series of post-docs covering a wide range
of models (but all within the sphere of molecular genetics/biology) from molecular
plant pathology at Iowa State University, through avian molecular immunology
(the Institute for Animal Health, Compton, UK), mammalian and human molecular
immunology (University of Nottingham) and bacterial molecular genetics (University
of Nottingham). Within the MBIG group I am conducting research analysing the
secretome of the serogroup B meningococcus, the predominant cause of meningococcal
disease in Britain and Europe.
1. Andrew J. Hall, Shaun Morroll and Franco H. Falcone. (2007). Induction
of chitotriosidase (chit1) gene expression in monocyte- derived human macrophages
by fungal pathogen associated recognition patterns (PAMPs) Submitted to Infection
and Immunity, additional data requested before resubmission.
2. Andrew J. Hall*, Shaun Morroll*, Patrick Tighe, Friedrich Götz and Franco
H. Falcone. (2008). Human chitotriosidase is expressed in the eye and lacrimal
gland and has an antimicrobial spectrum different from lysozyme. Microbes and
Infection, 10(1):69-78. (*=Joint 1st Author)
3. Andrew J. Hall, Rupert J. Quinnell, Andrew Raiko, Moses Lagog, Peter Siba,
Shaun Morroll and Franco H. Falcone. (2007). Allelic frequency of the 24bp mutation
in human chitotriosidase (CHIT1) in a population from a hookworm-endemic region
of Papua New Guinea. Infection, Genetics and Evolution, in press
4. Shaun Morroll, Sharon Turner and Franco H. Falcone. Structure-function relationship
in mammalian chitinase-like lectins (chilectins). Animal Lectins: A Functional
view (Taylor and Francis Group). Invited book chapter.
5. Kaiser P, Poh TY, Rothwell L, Avery S, Balu S, Pathania US, Hughes S, Goodchild
M, Morrell S, Watson M, Bumstead N, Kaufman J, Young JR. (2005) A genomic analysis
of chicken cytokines and chemokines.J Interferon Cytokine Res. 25(8):467-84.
6. Falcone FH, Morroll S, Gibbs BF. (2005) Lack of protease activated receptor
(PAR) expression in purified human basophils.Inflamm Res. 54 Suppl 1:S13-4.
7. Gary Leveque, Vincenzo Forgetta, Shaun Morroll, Nat Bumstead, Paul Barrow,
J.C. Loredo-Osti, Kenneth Morgan and Danielle Malo. (2003) Allelic variation
in TLR4 is linked to susceptibility to salmonella Typhimurium infection in chickens.
Infect Immun. 2003 Mar;71(3):1116-24.
8. Shaun Morroll, Marianne Goodchild, Neal G. Copeland, Debra J. Gilbert, Nancy
A. Jenkins, Nat Bumstead and Yvonne Boyd (2001) The gene encoding E-selectin
(SELE) and lymphotactin (SCYC1) lie on separate chicken chromosomes although
they are closely linked in human and mouse. Immunogenetics; 53 (6) 477-482.
9. Yvvone Boyd, Marianne Goodchild, Shaun Morroll and Nat Bumstead. (2001) Identification
of chicken toll-like receptor 2 (TLR2) and mapping to an evolutionary conserved
chromosomal segment in chicken and mouse. Immunogenetics; 52(3-4):294-8.
10. Zoe A. Wilson, Shaun M. Morroll, Janet Dawson, Ranjan Swarup and Paddy J.
Tighe (2001) The Arabidopsis MALE STERILITY1 (MS1) gene is a Transcriptional
regulator of male gametogenesis, with homology to the PHD-finger family of transcription
factors. (2001) Plant Journal, 28 (1) 27-39.
11. Wei F, Gobelman-Werner K, Morroll SM, Kurth J, Mao L, Wing R, Leister D,
Schulze-Lefert P and Wise RP (1999) The Mla (powdery mildew) resistance cluster
is associated with three NBS-LRR gene families and suppressed recombination
within a 240-kb DNA interval on chromosome 5S (1HS) of barley. Genetics, 153
(4):1929-48.
12. Morroll, S.M. and Wilson, Z.A. (1998) YAC restriction mapping of a region
involved in floral development on the top arm of Arabidopsis chromosome 5. Genome
41 (6): 806-817
13.Mulligan, B.J., Wilson, Z.A., Dawson, J., Kalantidis, K., Vizar, I., Briarty,
L.G., Thorlby, G., Morroll, S.M. & Schlumukov, L. (1994). The use of male
sterile mutants of Arabidopsis to identify genes essential for male gametophyte
development. Flowering Newsletter. 17:12-20.
14. Thorlby, G., Morroll, S.M., Vizar, I., Mulligan, B.J. & Wilson, Z.A
(1994). Physical and genetic map of lu-ttg region of Arabidopsis chromosome
five. J. Exp. Bot. Suppl. 45:18.
Molecular Bacteriology
and Immunology Group
Institute of Infection, Immunity and Inflammation
Centre for Biomolecular Sciences
University of Nottingham
University Park
Nottingham NG7 2RD
United Kingdom
Tel: (44) 115 846 8925
email: shaun.morroll@nottingham.ac.uk
Molecular Bacteriology and
Immunology Group
Division
of Microbiology & Infectious Diseases
University
of Nottingham