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Nottingham Digestive Diseases Centre

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Christopher Hawkey

Professor of Gastroenterology, Faculty of Medicine & Health Sciences

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Biography

Christopher Hawkey is Professor of Gastroenterology at the Nottingham Digestive Diseases Centre. His main interests are in the field of non-steroid anti-inflammatory drugs and inflammatory bowel disease. In both areas his approach is to try to identify targets in small exploratory studies and then evaluate them in large and/or outcomes studies.

Research Summary

Interests

  • Non-steroidal anti-inflammatory drugs
  • Inflammatory bowel disease
  • Chemoprophylaxis of gastrointestinal cancers

Techniques

  • Clinical trials including: Phase I assessments, particularly by endoscopy in volunteers Small proof of concept Phase II trials Clinical trial design, including Outcome studies
  • Ex-vivo translational research
  • Current research projects
  • Target Outcomes Study of selective vs non-selective NSAIDs

Recent Publications

  • HAWKEY, CHRISTOPHER J., LINDSAY, JAMES and GRIBBEN, JOHN, 2016. Stem Cell Transplantation for Refractory Crohn Disease Reply JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 315(23), 2620-2621
  • ATREYA, R., BLOOM, S., SCALDAFERI, F., GERARDI, V., ADMYRE, C., KARLSSON, A., KNITTEL, T., KOWALSKI, J., LUKAS, M., LOFBERG, R., PETRYKA, R., SCHNABEL, R., SEIDLER, U., NANCEY, S., NEURATH, M. and HAWKEY, C., 2016. The Toll-like-receptor 9 agonist DIMS0150 demonstrates therapeutic efficacy for the patient-reported outcome measures PRO-2 and ClinPRO in moderate-to-severe active ulcerative colitis JOURNAL OF CROHNS & COLITIS. 10, S41-S41
  • RIVAS, MANUEL A., GRAHAM, DANIEL, SULEM, PATRICK, STEVENS, CHRISTINE, DESCH, A. NICOLE, GOYETTE, PHILIPPE, GUDBJARTSSON, DANIEL, JONSDOTTIR, INGILEIF, THORSTEINSDOTTIR, UNNUR, DEGENHARDT, FRAUKE, MUCHA, SOEREN, KURKI, MITJA I., LI, DALIN, D'AMATO, MAURO, ANNESE, VITO, VERMEIRE, SEVERINE, WEERSMA, RINSE K., HALFVARSON, JONAS, PAAVOLA-SAKKI, PAULINA, LAPPALAINEN, MAARIT, LEK, MONKOL, CUMMINGS, BERYL, TUKIAINEN, TARU, HARITUNIANS, TALIN, HALME, LEENA, KOSKINEN, LOTTA L. E., ANANTHAKRISHNAN, ASHWIN N., LUO, YANG, HEAP, GRAHAM A., VISSCHEDIJK, MARIJN C., MACARTHUR, DANIEL G., NEALE, BENJAMIN M., AHMAD, TARIQ, ANDERSON, CARL A., BRANT, STEVEN R., DUERR, RICHARD H., SILVERBERG, MARK S., CHO, JUDY H., PALOTIE, AARNO, SAAVALAINEN, PAIVI, KONTULA, KIMMO, FARKKILA, MARTTI, MCGOVERN, DERMOT P. B., FRANKE, ANDRE, STEFANSSON, KARI, RIOUX, JOHN D., XAVIER, RAMNIK J. and DALY, MARK J., 2016. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis NATURE COMMUNICATIONS. 7,
  • LINDSAY, J., ALLEZ, M., CLARK, M., LABOPIN, M., RICART, E., ROGLER, G., ROVIRA, M., SATSANGI, J., FARGE, D. and HAWKEY, C., 2016. Prediction of clinical and endoscopic remission after autologous stem cell transplantation in treatment refractory Crohn's disease: pooled results from the ASTIC trial JOURNAL OF CROHNS & COLITIS. 10, S37-S38

School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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