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Nottingham Digestive Diseases Centre

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John Atherton

Pro Vice Chancellor; Dean of the Faculty of Medicine and Health Sciences; Professor of Gastroenterology, Faculty of Executive Office

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Biography

Dean of the School of Medicine, Faculty of Medicine and Health Sciences.

Co-Director, Nottingham Digestive Diseases Centre Biomedical Research Unit. This is a National Institute of Health Research-funded BRU within the Nottingham Digestive Diseases Centre. It organises patient-based translational research in gastroenterology and hepatology, and focuses particularly on infections and post-infectious sequelae.

Active research leader in the field of Helicobacter pylori, peptic ulceration and gastric carcinogenesis. We concentrate on laboratory and translational research. Our laboratory group of about 15 researchers is based in the Centre for Biomolecular Science (CBS) and is led by myself, Dr. Karen Robinson and Dr. Rob Delahay.

Practising Clinical Gastroenterologist looking after a wide range of patients but concentrating on upper GI conditions and difficult peptic ulceration, including resistant H. pylori infection.

Secretary-General of the United European Gastroenterology, the organisation responsible for delivering the yearly United European Digestive Diseases Week meeting, with about 14,000 participants.

Member of Council of the University of Nottingham - Council is the University's governing body

Member of the Medical Research Council Clinical Training Programme and Career Development Panel

Expertise Summary

I have leadership, research, teaching,leadership clinical roles. My personal research skills are in molecular microbiology and translational patient-based research. My clinical skills are in a wide range of gastroenterological conditions, specialising in upper GI diseases and Helicobacter pylori infection. I teach through interactive large and small group teaching, using patient-based ward teaching.

Research Summary

My research focuses on the gastric pathogen Helicobacter pylori and on upper gastrointestinal diseases such as peptic ulceration and gastric cancer. I supervise both laboratory and clinical research.… read more

Selected Publications

Current Research

My research focuses on the gastric pathogen Helicobacter pylori and on upper gastrointestinal diseases such as peptic ulceration and gastric cancer. I supervise both laboratory and clinical research. My personal expertise is in molecular microbiology and in translational research, but others in our group work on the immunology of infectious disease and on cellular bacteriology. Our main current interests are in H. pylori virulence factors and pathogenesis, H. pylori genetics, bacterial-cell interactions and signalling, H. pylori metabolism, and increasingly in the innate and acquired immune responses to H. pylori. An important feature of our research is that we focus on work which we believe will ultimately make a difference to patient care.

Future Research

Helicobacter pylori pathogenesis, the vacuolating cytotoxin, environmental and host determinants of virulence factor expression, genetic diversity, novel therapeutic targets, antibiotic delivery.

School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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