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Nottingham Digestive Diseases Centre

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Luca Marciani

Associate Professor in GI MRI, Faculty of Medicine & Health Sciences

Contact

  • workRoom E1412, E Floor West Block School of Medicine
    Queen's Medical Centre
    Nottingham
    NG7 2UH
    UK
  • work0115 823 1248
  • fax0115 823 1409

Biography

I graduated in Physics at the University of Genoa in Italy. I then worked in Milan and London before joining the University of Nottingham. I was awarded my PhD in Physics at the Sir Peter Mansfield Imaging Centre, where I worked on a series of multi-disciplinary research contracts. Thanks to a Wellcome Trust VIP Fellowship and a RCUK Academic Fellowship I moved to the School of Medicine, where I am now Associate Professor in Gastrointestinal MRI in the Nottingham Digestive Diseases Centre (NDDC).

My personal expertise is in imaging the human gastrointestinal (GI) tract using magnetic resonance imaging (MRI). My research focuses on gastrointestinal physiology and pathology using MRI methods in combination with other physiological and behavioural techniques. I have a particular interest in in-body imaging of foods, beverages, dosage forms and formulations, intestinal fluid distribution and the development of novel MRI tests for GI motility and transit. I work within a team that has developed a unique cross-disciplinary collaboration between gastroenterologists, surgeons, physiologists, MRI physicists, pharmaceutical scientists, food scientists and industrial collaborators from the food and pharmaceutical industry in the UK and abroad.

I have published 81 research papers and 11 book chapters, I have been principal investigator and co-investigator on academic and commercial research grants worth £7.8 million. I serve on the NIHR Nottingham Digestive Diseases Biomedical Research Centre Strategy Board and on the Sir Peter Mansfield Imaging Centre Science Committee. I was awarded the RinR/Wellcome/RCUK Communicator's Award for my science outreach work with secondary school pupils.

Teaching Summary

I have various teaching activities. I convene a faculty-wide postgraduate course on Biomedical Imaging in Research [MHSBIR] and teach gastrointestinal and brain imaging on the Diagnostic Imaging… read more

Research Summary

I lead a NIHR-funded project developing a new MRI medical device to measure gastrointestinal transit in paediatric constipation and the UK part of a FDA-funded project with the University of Michigan… read more

Selected Publications

Papers published: 81

Book contributions: 11

Times cited: 1951

ISI h-index: 23

i-index: 39

PGR students supervised so far: 12

Research Funding: co-investigator on grants totalling £7.8 million (of which £1.5 million as Principal Investigator)

Invited presentations: 30 (of which 14 internationally)

I have various teaching activities. I convene a faculty-wide postgraduate course on Biomedical Imaging in Research [MHSBIR] and teach gastrointestinal and brain imaging on the Diagnostic Imaging Technology undregraduate module [A13DIT]. I also teach food imaging in the body on the undergraduate Food and Physiology course [D211F5]. I supervise post-graduate research students (12 to date) and I act as internal examiner for the School. I regularly supervise (18 to date) and examine BMedSci students on their 3rd year research project and dissertation [A13HPS].

I completed my full Postgraduate Certificate in Higher Education (PGCHE) in 2013 and became Fellow of the Higher Education Academy.

In the past I also lectured on the Food and Health [D211F1] undergraduate module. Further back I have supervised 4th year Physics MSci research projects, I have been Personal Academic Tutor for 1st year Physics undergraduates and I also taught physics laboratories to a range of year groups in a high school for two years.

Current Research

I lead a NIHR-funded project developing a new MRI medical device to measure gastrointestinal transit in paediatric constipation and the UK part of a FDA-funded project with the University of Michigan using MRI to study the in vivo fluid and motility environment of the undisturbed gut, with a view to improve physiological relevance of in vitro testing methods and in silico transport analyses for prediction of bioperformance of oral dosage forms.

I also lead postgraduate research projects looking at gastrointestinal responses to breakfast porridges from different grains in healthy participants, to gluten free diet in coeliac disease and at the motility responses to feeding in Crohn's disease.

I am also involved in a range of projects within the Nottingham GI MRI Research Group. These include imaging of novel dosage forms, the development of novel luminal contrast agents, small bowel imaging in inflammatory diseases, colonic motility in constipation and the effect of various food materials on gastrointestinal function and symptoms in health and disease.

School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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