Contact

• workDept Histopathology, City Hospital Campus, Nottingham University Hospitals, Hucknall Rd
  Nottingham City Hospital
  Hucknall Road
  Nottingham
  NG5 1PB
  UK
• work0115 969 1169 56875
• fax0115 9627768
• ian.ellis@nottingham.ac.uk
• http://www.nottingham.ac.uk/research/groups/pathology/index.aspx

Biography

Professor Ian O. Ellis has been involved in the practice of pathology for over thirty years and has an international reputation in clinical and translational research in breast disease, particularly classification of breast cancer and evaluation of prognostic factors. Author of over 600 peer reviewed scientific publications, chapters in medical textbooks and specialist textbooks in pathology and an experienced lecturer being a founder member of the faculty of the Nottingham International Breast Education Centre. He is a Fellow and a past Specialty Advisor of The Royal College of Pathologists, past President of the Pathological Socity of Great Britain and Ireland, Past Chairman of the UK National Co-ordinating Committee for Breast Pathology, Past President of the International Society of Breast Pathology, past Councilor of The European Society of Mastology, Steering Committee Member of The European Group for Breast Screening Pathology and past Chairman of the Breast Pathology Working Group of the European Society of Pathology. He has acted as an advisor to theDoH, UICC, WHO and IARC. He is founder of PathLore and Medical Director of Source Bioscience.

Research Summary

The Nottingham/Tenovus Breast Cancer Research Group at Nottingham City Hospital has a longstanding research interest and international track record in classification of breast cancer diagnosis of… read more

Selected Publications

• CURTIS, C., SHAH, S.P., CHIN, S., TURASHVILI, G., RUEDA, O.M., DUNNING, M.J., SPEED, D., LYNCH, A.G., SAMARAJIWA, S., YUAN, Y., GRAF, S., HA, G., HAFFARI, G., BASHASHATI, A., RUSSELL, R., MCKINNEY, S., METABRIC GROUP, LANGEROD, A., GREEN, A., PROVENZANO, E., WISHART, G., PINDER, S., WATSON, P., MARKOWETZ, F., MURPHY, L., ELLIS, I., PURUSHOTHAM, A., BORRESEN-DAL, A., BRENTON, J.D., TAVARE, S., CALDAS, C. and APARACIO, S., 2012. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups Nature. 486(7403), 346-352
• ROSS-INNES, C.S., STARK, R., TESCHENDORFF, A.E., HOLMES, K.A., ALI, H.R., DUNNING, M.J., BROWN, G.D., GOJIS, O., ELLIS, I.O., GREEN, A.R., ALI, S., CHIN, S., PALMIERI, C., CALDAS, C. and CARROLL, J.S., 2012. Differential oestrogen receptor binding is associated with clinical outcome in breast cancer Nature. 481(7381), 389-393
• GIAMAS, G., FILIPOVIĆ, A., JACOB, J., MESSIER, W., ZHANG, H., YANG, D., ZHANG, W., SHIFA, B.A., PHOTIOU, A., TRALAU-STEWART, C., CASTELLANO, L., GREEN, A.R., COOMBES, R.C., ELLIS, I.O., ALI, S., LENZ, H.J. and STEBBING, J., 2011. Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer Nature Medicine. 17(6), 715-719
• CUZICK, J., SESTAK, I., PINDER, S.E., ELLIS, I.O., FORSYTH, S., BUNDRED, N.J., FORBES, J.F., BISHOP, H., FENTIMAN, I.S. and GEORGE, W.D., 2011. Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK/ANZ DCIS trial Lancet Oncology. 12(1), 21-29

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Current Research

The Nottingham/Tenovus Breast Cancer Research Group at Nottingham City Hospital has a longstanding research interest and international track record in classification of breast cancer diagnosis of breast disease, evaluation of prognostic factors in breast cancer and understanding of the mechanisms governing hormone response in breast cancer. We have developed a histological grading system, which has become the international gold standard for histological classification (WHO, UICC, EU and UK). The Nottingham Prognostic Index, also developed by the group, is regarded as the most effective system for clinical decision support in routine clinical management. These systems are largely based on morphological assessment of tumour tissue sections and are subject to problems of interobserver variation. As a consequence our group have examined a wide range of potential objective prognostic markers and have over the last 5 years been exploring the hypothesis that a novel classification of breast cancer based on phenotypic and molecular genetic characteristics will provide a more robust system for classification and therapeutic decision-making. This hypothesis has been confirmed in principle with recognition of novel classes of breast cancer defined through their protein expression characteristics. Further studies are in place to identify and examine the influence of novel proteins identified in this context.

Current studies include:

1) Use of tissue array technology to allow immunophenotypic characterisation of protein expression of a large series of approximately 2000 breast cancer cases from the Nottingham Tenovus Breast Cancer series. This will provide a baseline data set of known and important proteins expressed in breast cancer, the frequency of their expression and their associations. The hypothesis being that breast cancer exhibits a number of distinct phenotypes which are related to different differentiation pathways from stem cell to normal adult cell types and which are influential on tumour behaviour.

2) Molecular genetic analysis of specific lesions with a pure histological morphology using array comparative genomic hybridisation (CGH), CISH and immunocytochemical protein expression analysis.

3) A proteomic and molecular approach to characterisation of breast tumours

4) Mechanisms of hormone response and resistance in breast cancer

5) Examination of expression of each member of the Type 1 growth factor family in a large series of breast cancer cases examining the clinical effect of co expression of receptors and ligands.

Group resources include expertise in

Histology / Morphological assessment of tissue

Image analysis

Immunocytochemistry

Laser microdissection

Future Research

Aspects of breast cancer biology, pathology, molecular genetics, morphology, diagnosis, classification and behaviour

• HICKEY, T. E., SELTH, L. A., CHIA, K. M., LAVEN-LAW, G., MILIOLI, H. H., RODEN, D., JINDAL, S., HUI, M., FINLAY-SCHULTZ, J., EBRAHIMIE, E., BIRRELL, S. N., STELLOO, S., IGGO, R., ALEXANDROU, S., CALDON, C. E., ABDEL-FATAH, T. M., ELLIS, I. O., ZWART, W., PALMIERI, C., SARTORIUS, C. A., SWARBRICK, A., LIM, E., CARROLL, J. S. and TILLEY, W. D., 2021. The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer: Nat Med Nat Med.
• ANSARI, R. E., CRAZE, M. L., ALTHOBITI, M., ALFARSI, L., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2020. Enhanced glutamine uptake influences composition of immune cell infiltrates in breast cancer: Br J Cancer Br J Cancer. 122(1), 94-101
• RAKHA, E. A., QUINN, C. M., FOSCHINI, M. P., MUNOZ MARTIN, M., DABBS, D. J., LAKHANI, S., VARGA, Z., PINDER, S. E., SCHMITT, F. C., REIS-FILHO, J. S., FOX, S. B., ELLIS, I. O., TAN, P. H. and MIHAI, R., 2020. Metaplastic carcinomas of the breast without evidence of epithelial differentiation: a diagnostic approach for management: Histopathology Histopathology.
• DUFFY, S. W., VULKAN, D., CUCKLE, H., PARMAR, D., SHEIKH, S., SMITH, R. A., EVANS, A., BLYUSS, O., JOHNS, L., ELLIS, I. O., MYLES, J., SASIENI, P. D. and MOSS, S. M., 2020. Effect of mammographic screening from age 40 years on breast cancer mortality (UK Age trial): final results of a randomised, controlled trial: Lancet Oncol Lancet Oncol. 21(9), 1165-1172
• KUROZUMI, S., ALSALEEM, M., MONTEIRO, C. J., BHARDWAJ, K., JOOSTEN, S. E. P., FUJII, T., SHIRABE, K., GREEN, A. R., ELLIS, I. O., RAKHA, E. A., MONGAN, N. P., HEERY, D. M., ZWART, W., OESTERREICH, S. and JOHNSTON, S. J., 2020. Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis of public datasets: Breast Cancer Res Breast Cancer Res. 22(1), 85
• ABDEL-FATAH, T. M. A., BALL, G. R., THANGAVELU, P. U., REID, L. E., MCCART REED, A. E., SAUNUS, J. M., DUIJF, P. H. G., SIMPSON, P. T., LAKHANI, S. R., PONGOR, L., GYORFFY, B., MOSELEY, P. M., GREEN, A. R., POCKLEY, A. G., CALDAS, C., ELLIS, I. O. and CHAN, S. Y. T., 2020. Association of Sperm-Associated Antigen 5 and Treatment Response in Patients With Estrogen Receptor-Positive Breast Cancer: JAMA Netw Open JAMA Netw Open. 3(7), e209486
• ALFARSI, L. H., EL ANSARI, R., MASISI, B. K., PARKS, R., MOHAMMED, O. J., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2020. Integrated Analysis of Key Differentially Expressed Genes Identifies DBN1 as a Predictive Marker of Response to Endocrine Therapy in Luminal Breast Cancer: Cancers (Basel) Cancers (Basel). 12(6),
• ALFARSI, L. H., EL ANSARI, R., CRAZE, M. L., MASISI, B. K., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2020. PPFIA1 expression associates with poor response to endocrine treatment in luminal breast cancer: BMC Cancer BMC Cancer. 20(1), 425
• LEE, A. H. S., HODI, Z., SOOMRO, I., SOVANI, V., ABBAS, A., RAKHA, E. and ELLIS, I. O., 2020. Histological clues to the diagnosis of metastasis to the breast from extramammary malignancies: Histopathology Histopathology. 77(2), 303-313
• EL ANSARI, R., ALFARSI, L., CRAZE, M. L., MASISI, B. K., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2020. The solute carrier SLC7A8 is a marker of favourable prognosis in ER-positive low proliferative invasive breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat. 181(1), 1-12
• ALFARSI, L. H., EL-ANSARI, R., CRAZE, M. L., MASISI, B. K., MOHAMMED, O. J., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2020. Co-Expression Effect of SLC7A5/SLC3A2 to Predict Response to Endocrine Therapy in Oestrogen-Receptor-Positive Breast Cancer: Int J Mol Sci Int J Mol Sci. 21(4),
• PAREJA, F., TOSS, M. S., GEYER, F. C., DA SILVA, E. M., VAHDATINIA, M., SEBASTIAO, A. P. M., SELENICA, P., SZATROWSKI, A., EDELWEISS, M., WEN, H. Y., MIHAI, R., VARGA, Z., FOSCHINI, M. P., RUBIN, B. P., ELLIS, I. O., CHANDARLAPATY, S., JUNGBLUTH, A. A., BROGI, E., WEIGELT, B., REIS-FILHO, J. S. and RAKHA, E. A., 2020. Immunohistochemical assessment of HRAS Q61R mutations in breast adenomyoepitheliomas: Histopathology Histopathology. 76(6), 865-874
• ALFARSI, L. H., ELANSARI, R., TOSS, M. S., DIEZ-RODRIGUEZ, M., NOLAN, C. C., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2019. Kinesin family member-18A (KIF18A) is a predictive biomarker of poor benefit from endocrine therapy in early ER+ breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat. 173(1), 93-102
• ZILIOTTO, S., GEE, J. M. W., ELLIS, I. O., GREEN, A. R., FINLAY, P., GOBBATO, A. and TAYLOR, K. M., 2019. Activated zinc transporter ZIP7 as an indicator of anti-hormone resistance in breast cancer: Metallomics Metallomics. 11(9), 1579-1592
• ALFARSI, L. H., ANSARI, R. E., CRAZE, M. L., TOSS, M. S., MASISI, B., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2019. CDC20 expression in oestrogen receptor positive breast cancer predicts poor prognosis and lack of response to endocrine therapy: Breast Cancer Res Treat Breast Cancer Res Treat. 178(3), 535-544
• BHATTARAI, S., KLIMOV, S., ALESKANDARANY, M. A., BURRELL, H., WORMALL, A., GREEN, A. R., RIDA, P., ELLIS, I. O., OSAN, R. M., RAKHA, E. A. and ANEJA, R., 2019. Machine learning-based prediction of breast cancer growth rate in vivo: Br J Cancer Br J Cancer. 121(6), 497-504
• KLIMOV, S., MILIGY, I. M., GERTYCH, A., JIANG, Y., TOSS, M. S., RIDA, P., ELLIS, I. O., GREEN, A., KRISHNAMURTI, U., RAKHA, E. A. and ANEJA, R., 2019. A whole slide image-based machine learning approach to predict ductal carcinoma in situ (DCIS) recurrence risk: Breast Cancer Res Breast Cancer Res. 21(1), 83
• BHATTARAI, S., KLIMOV, S., MITTAL, K., KRISHNAMURTI, U., LI, X. B., OPREA-ILIES, G., WETHERILT, C. S., RIAZ, A., ALESKANDARANY, M. A., GREEN, A. R., ELLIS, I. O., CANTUARIA, G., GUPTA, M., MANNE, U., AGBOOLA, J., BASKOVICH, B., JANSSEN, E. A. M., CALLAGY, G., WALSH, E. M., MEHTA, A., DOGRA, A., SHET, T., GAJARIA, P., TRAINA, T., NGGADA, H. A., OMONISI, A., AHMED, S. A., RAKHA, E. A., RIDA, P. and ANEJA, R., 2019. Prognostic Role of Androgen Receptor in Triple Negative Breast Cancer: A Multi-Institutional Study: Cancers (Basel) Cancers (Basel). 11(7),
• MILIGY, I. M., TOSS, M. S., KHOUT, H., WHISKER, L., BURRELL, H. C., ELLIS, I. O., GREEN, A. R., MACMILLAN, D. and RAKHA, E. A., 2019. Surgical management of ductal carcinoma in situ of the breast: A large retrospective study from a single institution: Breast J Breast J. 25(6), 1143-1153
• TOSS, M. S., MILIGY, I. M., GORRINGE, K. L., ALESKANDARANY, M. A., ALKAWAZ, A., MITTAL, K., ANEJA, R., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2019. Collagen (XI) alpha-1 chain is an independent prognostic factor in breast ductal carcinoma in situ: Mod Pathol Mod Pathol. 32(10), 1460-1472
• TOSS, M. S., MILIGY, I. M., GORRINGE, K. L., ALKAWAZ, A., MITTAL, K., ANEJA, R., ELLIS, I. O., GREEN, A. R., ROXANIS, I. and RAKHA, E. A., 2019. Geometric characteristics of collagen have independent prognostic significance in breast ductal carcinoma in situ: an image analysis study: Mod Pathol Mod Pathol. 32(10), 1473-1485
• JONES, J. L., HANBY, A. M., WELLS, C., CALAMINICI, M., JOHNSON, L., TURTON, P., DEB, R., PROVENZANO, E., SHAABAN, A., ELLIS, I. O., PINDER, S. E. and NATIONAL CO-ORDINATING COMMITTEE OF BREAST, PATHOLOGY, 2019. Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL): an overview of presentation and pathogenesis and guidelines for pathological diagnosis and management: Histopathology Histopathology. 75(6), 787-796
• MILIGY, I. M., TOSS, M. S., GORRINGE, K. L., LEE, A. H. S., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2019. The clinical and biological significance of HER2 over-expression in breast ductal carcinoma in situ: a large study from a single institution: Br J Cancer Br J Cancer. 120(11), 1075-1082
• RUEDA, O. M., SAMMUT, S. J., SEOANE, J. A., CHIN, S. F., CASWELL-JIN, J. L., CALLARI, M., BATRA, R., PEREIRA, B., BRUNA, A., ALI, H. R., PROVENZANO, E., LIU, B., PARISIEN, M., GILLETT, C., MCKINNEY, S., GREEN, A. R., MURPHY, L., PURUSHOTHAM, A., ELLIS, I. O., PHAROAH, P. D., RUEDA, C., APARICIO, S., CALDAS, C. and CURTIS, C., 2019. Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups: Nature Nature. 567(7748), 399-404
• ABDEL-FATAH, T. M. A., BROOM, R. J., LU, J., MOSELEY, P. M., HUANG, B., LI, L., LIU, S., CHEN, L., MA, R. Z., CAO, W., WANG, X., LI, Y., PERRY, J. K., ALESKANDARANY, M., NOLAN, C. C., RAKHA, E. A., LOBIE, P. E., CHAN, S. Y. T., ELLIS, I. O., HWANG, L. A., LANE, D. P., GREEN, A. R. and LIU, D. X., 2019. SHON expression predicts response and relapse risk of breast cancer patients after anthracycline-based combination chemotherapy or tamoxifen treatment: Br J Cancer Br J Cancer. 120(7), 728-745
• KOH, V. C. Y., LIM, J. C. T., THIKE, A. A., CHEOK, P. Y., THU, M. M. M., LI, H., TAN, V. K. M., ONG, K. W., TAN, B. K. T., HO, G. H., THILAGARATNAM, S., WONG, J. S. L., WONG, F. Y., ELLIS, I. O. and TAN, P. H., 2019. Behaviour and characteristics of low-grade ductal carcinoma in situ of the breast: literature review and single-centre retrospective series: Histopathology Histopathology. 74(7), 970-987
• TOSS, M. S., MILIGY, I. M., HAJ-AHMAD, R., GORRINGE, K. L., ALKAWAZ, A., MITTAL, K., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2019. The prognostic significance of lysosomal protective protein (cathepsin A) in breast ductal carcinoma in situ: Histopathology Histopathology. 74(7), 1025-1035
• PAREJA, F., GEYER, F. C., BROWN, D. N., SEBASTIAO, A. P. M., GULARTE-MERIDA, R., LI, A., EDELWEISS, M., DA CRUZ PAULA, A., SELENICA, P., WEN, H. Y., JUNGBLUTH, A. A., VARGA, Z., PALAZZO, J., RUBIN, B. P., ELLIS, I. O., BROGI, E., RAKHA, E. A., WEIGELT, B. and REIS-FILHO, J. S., 2019. Assessment of HMGA2 and PLAG1 rearrangements in breast adenomyoepitheliomas: NPJ Breast Cancer NPJ Breast Cancer. 5, 6
• EL-ANSARI, R., CRAZE, M. L., ALFARSI, L., SORIA, D., DIEZ-RODRIGUEZ, M., NOLAN, C. C., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2019. The combined expression of solute carriers is associated with a poor prognosis in highly proliferative ER+ breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat. 175(1), 27-38
• ALHUDIRI, I. M., NOLAN, C. C., ELLIS, I. O., ELZAGHEID, A., RAKHA, E. A., GREEN, A. R. and CHAPMAN, C. J., 2019. Expression of Lamin A/C in early-stage breast cancer and its prognostic value: Breast Cancer Res Treat Breast Cancer Res Treat. 174(3), 661-668
• TOSS, M. S., MILIGY, I. M., GORRINGE, K. L., MCCAFFREY, L., ALKAWAZ, A., ABIDI, A., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2019. Legumain is an independent predictor for invasive recurrence in breast ductal carcinoma in situ: Mod Pathol Mod Pathol. 32(5), 639-649
• QAISER T, MUKHERJEE A, REDDY PB C, MUNUGOTI SD, TALLAM V, PITKÄAHO T, LEHTIMÄKI T, NAUGHTON T, BERSETH M, PEDRAZA A, MUKUNDAN R, SMITH M, BHALERAO A, RODNER E, SIMON M, DENZLER J, HUANG CH, BUENO G, SNEAD D, ELLIS IO, ILYAS M and RAJPOOT N, 2018. Her2 Challenge Contest: A Detailed Assessment of Automated Her2 Scoring Algorithms in Whole Slide Images of Breast Cancer Tissues. Histopathology. 72(2), 227-238
• ALESKANDARANY MA, SONBUL S, SURRIDGE R, MUKHERJEE A, CALDAS C, DIEZ-RODRIGUEZ M, ASHANKYTY I, ALBRAHIM KI, ELMOUNA AM, ANEJA R, MARTIN SG, ELLIS IO, GREEN AR and RAKHA EA, 2018. Rho-GTPase activating-protein 18: a biomarker associated with good prognosis in invasive breast cancer. British journal of cancer. 117(8), 1176-1184
• PU X, STORR SJ, AHMAD NS, RAKHA EA, GREEN AR, ELLIS IO and MARTIN SG, 2018. High nuclear MSK1 is associated with longer survival in breast cancer patients. Journal of cancer research and clinical oncology. 144(3), 509-517
• ABDEL-FATAH TMA, REES RC, POCKLEY AG, MOSELEY P, BALL GR, CHAN SYT, ELLIS IO and MILES AK, 2018. The localization of pre mRNA splicing factor PRPF38B is a novel prognostic biomarker that may predict survival benefit of trastuzumab in patients with breast cancer overexpressing HER2. Oncotarget. 8(68), 112245-112257
• TOSS, M. S., MILIGY, I. M., GORRINGE, K. L., ALKAWAZ, A., KHOUT, H., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2018. Prolyl-4-hydroxylase Alpha subunit 2 (P4HA2) expression is a predictor of poor outcome in breast ductal carcinoma in situ (DCIS): Br J Cancer Br J Cancer. 119(12), 1518-1526
• PAREJA, F., BRANDES, A. H., BASILI, T., SELENICA, P., GEYER, F. C., FAN, D., DA CRUZ PAULA, A., KUMAR, R., BROWN, D. N., GULARTE-MERIDA, R., ALEMAR, B., BI, R., LIM, R. S., DE BRUIJN, I., FUJISAWA, S., GARDNER, R., FENG, E., LI, A., DA SILVA, E. M., LOZADA, J. R., BLECUA, P., COHEN-GOULD, L., JUNGBLUTH, A. A., RAKHA, E. A., ELLIS, I. O., EDELWEISS, M. I. A., PALAZZO, J., NORTON, L., HOLLMANN, T., EDELWEISS, M., RUBIN, B. P., WEIGELT, B. and REIS-FILHO, J. S., 2018. Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors: Nat Commun Nat Commun. 9(1), 3533
• HUTCHESON, I. R., KNOWLDEN, J. M., HISCOX, S. E., BARROW, D., GEE, J. M. W., ROBERTSON, J. F., ELLIS, I. O. and NICHOLSON, R. I., 2018. Correction to: Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells: Breast Cancer Res Breast Cancer Res. 20(1), 98
• SHIPP, D. W., RAKHA, E. A., KOLOYDENKO, A. A., MACMILLAN, R. D., ELLIS, I. O. and NOTINGHER, I., 2018. Intra-operative spectroscopic assessment of surgical margins during breast conserving surgery: Breast Cancer Res Breast Cancer Res. 20(1), 69
• MILIGY, I. M., GORRINGE, K. L., TOSS, M. S., AL-KAWAZ, A. A., SIMPSON, P., DIEZ-RODRIGUEZ, M., NOLAN, C. C., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2018. Thioredoxin-interacting protein is an independent risk stratifier for breast ductal carcinoma in situ: Mod Pathol Mod Pathol. 31(12), 1807-1815
• WOLFF, A. C., HAMMOND, M. E. H., ALLISON, K. H., HARVEY, B. E., MANGU, P. B., BARTLETT, J. M. S., BILOUS, M., ELLIS, I. O., FITZGIBBONS, P., HANNA, W., JENKINS, R. B., PRESS, M. F., SPEARS, P. A., VANCE, G. H., VIALE, G., MCSHANE, L. M. and DOWSETT, M., 2018. Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update: J Clin Oncol J Clin Oncol. 36(20), 2105-2122
• WOLFF, A. C., HAMMOND, M. E. H., ALLISON, K. H., HARVEY, B. E., MANGU, P. B., BARTLETT, J. M. S., BILOUS, M., ELLIS, I. O., FITZGIBBONS, P., HANNA, W., JENKINS, R. B., PRESS, M. F., SPEARS, P. A., VANCE, G. H., VIALE, G., MCSHANE, L. M. and DOWSETT, M., 2018. Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update: Arch Pathol Lab Med Arch Pathol Lab Med. 142(11), 1364-1382
• GEYER, F. C., LI, A., PAPANASTASIOU, A. D., SMITH, A., SELENICA, P., BURKE, K. A., EDELWEISS, M., WEN, H. C., PISCUOGLIO, S., SCHULTHEIS, A. M., MARTELOTTO, L. G., PAREJA, F., KUMAR, R., BRANDES, A., FAN, D., BASILI, T., DA CRUZ PAULA, A., LOZADA, J. R., BLECUA, P., MUENST, S., JUNGBLUTH, A. A., FOSCHINI, M. P., WEN, H. Y., BROGI, E., PALAZZO, J., RUBIN, B. P., NG, C. K. Y., NORTON, L., VARGA, Z., ELLIS, I. O., RAKHA, E. A., CHANDARLAPATY, S., WEIGELT, B. and REIS-FILHO, J. S., 2018. Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas: Nat Commun Nat Commun. 9(1), 1816
• RAKHA, E. A., ABBAS, A., PINTO AHUMADA, P., ELSAYED, M. E., COLMAN, D., PINDER, S. E. and ELLIS, I. O., 2018. Diagnostic concordance of reporting lymphovascular invasion in breast cancer: J Clin Pathol J Clin Pathol. 71(9), 802-805
• MUKHERJEE, A., RUSSELL, R., CHIN, S. F., LIU, B., RUEDA, O. M., ALI, H. R., TURASHVILI, G., MAHLER-ARAUJO, B., ELLIS, I. O., APARICIO, S., CALDAS, C. and PROVENZANO, E., 2018. Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort: NPJ Breast Cancer NPJ Breast Cancer. 4, 5
• PU X, STORR SJ, ZHANG Y, RAKHA EA, GREEN AR, ELLIS IO and MARTIN SG, 2017. Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival. Apoptosis : an international journal on programmed cell death. 22, 3
• ALEXANDER A, KARAKAS C, CHEN X, CAREY JP, YI M, BONDY M, THOMPSON P, CHEUNG KL, ELLIS IO, GONG Y, KRISHNAMURTHY S, ALVAREZ RH, UENO NT, HUNT KK and KEYOMARSI K, 2017. Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer. Oncotarget. (In Press.)
• MUFTAH AA, ALESKANDARANY MA, AL-KAABI MM, SONBUL SN, DIEZ-RODRIGUEZ M, NOLAN CC, CALDAS C, ELLIS IO, RAKHA EA and GREEN AR, 2017. Ki67 expression in invasive breast cancer: the use of tissue microarrays compared with whole tissue sections. Breast cancer research and treatment. (In Press.)
• CHRYSANTHOU E, GORRINGE KL, JOSEPH C, CRAZE M, NOLAN CC, DIEZ-RODRIGUEZ M, GREEN AR, RAKHA EA, ELLIS IO and MUKHERJEE A, 2017. Phenotypic characterisation of breast cancer: the role of CDC42. Breast cancer research and treatment.
• SONBUL SN, GORRINGE KL, ALESKANDARANY MA, MUKHERJEE A, GREEN AR, ELLIS IO and RAKHA EA, 2017. Chemokine (C-C motif) receptor 7 (CCR7) associates with the tumour immune microenvironment but not progression in invasive breast carcinoma. The journal of pathology. Clinical research. 3(2), 105-114
• MILIGY I, MOHAN P, GABER A, ALESKANDARANY MA, NOLAN CC, DIEZ-RODRIGUEZ M, MUKHERJEE A, CHAPMAN C, ELLIS IO, GREEN AR and RAKHA EA, 2017. Prognostic significance of Tumour infiltrating B-Lymphocytes in Breast Ductal Carcinoma in Situ. Histopathology. 71(2), :258-268
• GREEN AR, ALESKANDARANY MA, ALI R, HODGSON EG, ATABANI S, DE SOUZA K, RAKHA EA, ELLIS IO and MADHUSUDAN S, 2017. Clinical Impact of Tumor DNA Repair Expression and T-cell Infiltration in Breast Cancers. Cancer immunology research. 5(4), 292-299
• CANDIDO DOS REIS FJ, WISHART GC, DICKS EM, GREENBERG D, RASHBASS J, SCHMIDT MK, VAN DEN BROEK AJ, ELLIS IO, GREEN A, RAKHA E, MAISHMAN T, ECCLES DM and PHAROAH PDP, 2017. An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation. Breast cancer research : BCR. 19(1), 58
• EL ANSARI R, MCINTYRE A, CRAZE ML, ELLIS IO, RAKHA EA and GREEN AR, 2017. Altered glutamine metabolism in breast cancer; subtype dependencies and alternative adaptations. Histopathology. (In Press.)
• TOSS M, MILIGY I, THOMPSON AM, KHOUT H, GREEN AR, ELLIS IO and RAKHA EA, 2017. Current trials to reduce surgical intervention in ductal carcinoma in situ of the breast: Critical review. Breast (Edinburgh, Scotland). 35, 151-156 (In Press.)
• KLIMOV S, RIDA PC, ALESKANDARANY MA, GREEN AR, ELLIS IO, JANSSEN EA, RAKHA EA and ANEJA R, 2017. Novel immunohistochemistry-based signatures to predict metastatic site of triple-negative breast cancers. British journal of cancer. (In Press.)
• RAKHA EA, MILIGY I, GORRINGE KL, TOSS MS, GREEN AR, FOX SB, SCHMITT FC, TAN PH, TSE GM, BADVE S, DECKER T, VINCENT-SALOMON A, DABBS DJ, FOSCHINI MP, MORENO F, WENTAO Y, GEYER FC, REIS-FILHO JS, PINDER SE, LAKHANI SR and ELLIS IO, 2017. Invasion in breast lesions: the role of the epithelial-stroma barrier. Histopathology. (In Press.)
• RAKHA EA and ELLIS IO, 2017. Diagnostic challenges in papillary lesions of the breast. Pathology. (In Press.)
• CRAZE ML, CHEUNG H, JEWA N, COIMBRA NDM, SORIA D, EL-ANSARI R, ALESKANDARANY MA, WAI CHENG K, DIEZ-RODRIGUEZ M, NOLAN CC, ELLIS IO, RAKHA EA and GREEN AR, 2017. MYC regulation of glutamine-proline regulatory axis is key in luminal B breast cancer. British journal of cancer. (In Press.)
• NAIDOO K, WAI PT, MAGUIRE SL, DALEY F, HAIDER S, KRIPLANI D, CAMPBELL J, MIRZA H, GRIGORIADIS A, TUTT A, MOSELEY PM, ABDEL-FATAH TMA, CHAN SY, MADHUSUDAN S, RAKHA EA, ELLIS IO, LORD CJ, YUAN Y, GREEN AR and NATRAJAN R, 2017. Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response Targeted Therapies in Breast Cancer. Molecular cancer therapeutics. (In Press.)
• REIS-FILHO JS, GEYER FC, WEIGELT B, RAKHA EA, ELLIS IO and SCHNITT SJ, 2017. Reply to Rosen. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 30(10), 1505-1506
• GEYER FC, PAREJA F, WEIGELT B, RAKHA E, ELLIS IO, SCHNITT SJ and REIS-FILHO JS, 2017. The Spectrum of Triple-Negative Breast Disease: High- and Low-Grade Lesions. The American journal of pathology. 187(10), 2139-2151
• FOSCHINI MP, ASIOLI S, FOREID S, CSERNI G, ELLIS IO, EUSEBI V and ROSAI J, 2017. Solid Papillary Breast Carcinomas Resembling the Tall Cell Variant of Papillary Thyroid Neoplasms: A Unique Invasive Tumor With Indolent Behavior. The American journal of surgical pathology. 41(7), 887-895
• MITTAL K, CHOI DH, OGDEN A, DONTHAMSETTY S, MELTON BD, GUPTA MV, PANNU V, CANTUARIA G, VARAMBALLY S, REID MD, JONSDOTTIR K, JANSSEN EA, ALESKANDARANY MA, ELLIS IO, RAKHA EA, RIDA PC and ANEJA R, 2017. Amplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cells. Scientific reports. 7, 43984
• HUMPHRIES MP, SUNDARA RAJAN S, HONARPISHEH H, CSERNI G, DENT J, FULFORD L, JORDAN LB, JONES JL, KANTHAN R, LITWINIUK M, DI BENEDETTO A, MOTTOLESE M, PROVENZANO E, SHOUSHA S, STEPHENS M, KULKA J, ELLIS IO, TITLOYE AN, HANBY AM, SHAABAN AM and SPEIRS V, 2017. Characterisation of male breast cancer: a descriptive biomarker study from a large patient series. Scientific reports. 7, 45293
• SYED BM, MORGAN D, SETTY T, GREEN AR, PAISH EC, ELLIS IO and CHEUNG KL, 2017. Oestrogen receptor negative early operable primary breast cancer in older women-Biological characteristics and long-term clinical outcome. PloS one. 12(12), e0188528
• AHMAD N, AMMAR A, STORR SJ, GREEN AR, RAKHA E, ELLIS IO and MARTIN SG, 2017. IL-6 and IL-10 are associated with good prognosis in early stage invasive breast cancer patients. Cancer immunology, immunotherapy : CII. (In Press.)
• GUERINI-ROCCO, ELENA, PISCUOGLIO, SALVATORE, NG, CHARLOTTE K. Y., GEYER, FELIPE C., DE FILIPPO, MARIA R., EBERLE, CAREY A., AKRAM, MUZAFFAR, FUSCO, NICOLA, ICHIHARA, SHU, SAKR, RITA A., YATABE, YASUSHI, VINCENT-SALOMON, ANNE, RAKHA, EMAD A., ELLIS, IAN O., WEN, Y. HANNAH, WEIGELT, BRITTA, SCHNITT, STUART J. and REIS-FILHO, JORGE S., 2016. Microglandular adenosis associated with triple-negative breast cancer is a neoplastic lesion of triple-negative phenotype harbouring TP53 somatic mutations JOURNAL OF PATHOLOGY. 238(5), 677-688
• ALESKANDARANY, MOHAMMED A., AGARWAL, DEVIKA, NEGM, OLA H., BALL, GRAHAM, ELMOUNA, AHMED, ASHANKYTY, IBRAHEEM, NUGLOZEH, EDEM, FAZALUDEEN, MOHAMMAD F., DIEZ-RODRIGUEZ, MARIA, NOLAN, CHRISTOPHER C., TIGHE, PATRICK J., GREEN, ANDREW R., ELLIS, IAN O. and RAKHA, EMAD A., 2016. The prognostic significance of STAT3 in invasive breast cancer: analysis of protein and mRNA expressions in large cohorts BREAST CANCER RESEARCH AND TREATMENT. 156(1), 9-20
• GREEN, ANDREW R., SORIA, D., POWE, D. G., NOLAN, C. C., ALESKANDARANY, M., SZASZ, M. A., TOKES, A. M., BALL, G. R., GARIBALDI, J. M., RAKHA, E. A., KULKA, J. and ELLIS, I. O., 2016. Nottingham prognostic index plus (NPI plus ) predicts risk of distant metastases in primary breast cancer BREAST CANCER RESEARCH AND TREATMENT. 157(1), 65-75
• ARORA, ARVIND, AGARWAL, DEVIKA, ABDEL-FATAH, TAREK M. A., LU, HUIMING, CROTEAU, DEBORAH L., MOSELEY, PAUL, ALESKANDARANY, MOHAMMED A., GREEN, ANDREW R., BALL, GRAHAM, RAKHA, EMAD A., CHAN, STEPHEN Y. T., ELLIS, IAN O., WANG, LISA L., ZHAO, YONGLIANG, BALAJEE, ADAYABALAM S., BOHR, VILHELM A. and MADHUSUDAN, SRINIVASAN, 2016. RECQL4 helicase has oncogenic potential in sporadic breast cancers JOURNAL OF PATHOLOGY. 238(4), 495-501
• ALBANGHALI, MOHAMMAD, GREEN, ANDREW, RAKHA, EMAD, ALESKANDARANY, MOHAMED, NOLAN, CHRIS, ELLIS, IAN and CHEUNG, KWOK-LEUNG, 2016. Construction of tissue microarrays from core needle biopsies - a systematic literature review HISTOPATHOLOGY. 68(3), 323-332
• KLIMOV, SERGEY, GREEN, ANDREW, ALESKANDARANY, MOHAMMED A., RAKHA, EMAD, ELLIS, IAN O., REID, MICHELLE, RIDA, PADMASHREE C. G. and ANEJA, RITU, 2016. Predicting Metastatic Site of Triple Negative Breast Cancers Using Immunohistochemical Biomarkers MODERN PATHOLOGY. 29, 51A-51A
• KLIMOV, SERGEY, GREEN, ANDREW, ALESKANDARANY, MOHAMMED A., RAKHA, EMAD, ELLIS, IAN O., CANTUARIA, GUILHERME, AGBOOLA, AYODEJI O., REID, MICHELLE, LI, XIAOXIAN, RIDA, PADMASHREE C. G. and ANEJA, RITU, 2016. A Novel Risk-Predictive Metric Stratifies Triple-Negative Breast Cancers Based on Cell Cycling Kinetics MODERN PATHOLOGY. 29, 51A-51A
• KLIMOV, SERGEY, GREEN, ANDREW, ALESKANDARANY, MOHAMMED A., RAKHA, EMAD, ELLIS, IAN O., REID, MICHELLE, RIDA, PADMASHREE C. G. and ANEJA, RITU, 2016. Predicting Metastatic Site of Triple Negative Breast Cancers Using Immunohistochemical Biomarkers LABORATORY INVESTIGATION. 96, 51A-51A
• ARORA, ARVIND, ABDEL-FATAH, TAREK M. A., AGARWAL, DEVIKA, DOHERTY, RACHEL, CROTEAU, DEBORAH L., MOSELEY, PAUL M., HAMEED, KHALID, GREEN, ANDREW, ALESKANDARANY, MOHAMMED A., RAKHA, EMAD A., PATTERSON, KARL, BALL, GRAHAM, CHAN, STEPHEN Y. T., ELLIS, IAN O., BOHR, VILHELM A., BRYANT, HELEN E. and MADHUSUDAN, SRINIVASAN, 2016. Clinicopathological and prognostic significance of RECQL5 helicase expression in breast cancers CARCINOGENESIS. 37(1), 63-71
• GEYEI, FELIPE C., PISCUOGLIO, SALVATORE, NG, CHARLOTTE K. Y., GUERINI-ROCCO, ELENA, MARCHIO, CATERINA, HODI, ZSOLT, RAKHA, EMAD, ELLIS, IAN O., SCHNITT, STUART, WEIGELT, BRITTA and REIS-FILHO, JORGE S., 2016. Are Microglandular Adenosis and Breast Acinic Cell Carcinomas Related Lesions? MODERN PATHOLOGY. 29, 42A-42A
• ALESKANDARANY, M. A., GREEN, A. R., ASHANKYTY, I., ELMOUNA, A., DIEZ-RODRIGUEZ, M., NOLAN, C. C., ELLIS, I. O. and RAKHA, E. A., 2016. Impact of intratumoural heterogeneity on the assessment of Ki67 expression in breast cancer BREAST CANCER RESEARCH AND TREATMENT. 158(2), 287-295
• GREEN, ANDREW R., ALESKANDARANY, MOHAMMED A., AGARWAL, DEVIKA, ELSHEIKH, SOMAIA, NOLAN, CHRISTOPHER C., DIEZ-RODRIGUEZ, MARIA, MACMILLAN, R. DOUGLAS, BALL, GRAHAM R., CALDAS, CARLOS, MADHUSUDAN, SRINIVASAN, ELLIS, IAN O. and RAKHA, EMAD A., 2016. MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours BRITISH JOURNAL OF CANCER. 114(8), 917-928
• RAKHA, EMAD A., BADVE, SUNIL, EUSEBI, VINCENZO, REIS-FILHO, JORGE S., FOX, STEPHEN B., DABBS, DAVID J., DECKER, THOMAS, HODI, ZSOLT, ICHIHARA, SHU, LEE, ANDREW H. S., PALACIOS, JOSE, RICHARDSON, ANDREA L., VINCENT-SALOMON, ANNE, SCHMITT, FERNANDO C., PUAY-HOON TAN, TSE, GARY M. and ELLIS, IAN O., 2016. Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management HISTOPATHOLOGY. 68(1), 45-56
• PAPANASTASIOU, ANASTASIOS D., WEN, HUEI CHI, SCHULTHEIS, ANNE M., NG, CHARLOTTE K. Y., EDELWEISS, MARCIA, PISCUOGLIO, SALVATORE, MARTELOTTO, LUCIANO G., GEYER, FELIPE C., BURKE, KATHLEEN, DE FILIPPO, MARIA ROSARIA, MACEDO, GABRIEL S., VARGA, ZSUZSANNA, RAKHA, EMAD, ELLIS, IAN O., RUBIN, BRIAN P., WEIGELT, BRITTA and REIS-FILHO, JORGE S., 2016. The Mutational Landscape of Breast Adenomyoepitheliomas MODERN PATHOLOGY. 29, 64A-64A
• OGDEN, ANGELA, GREEN, ANDREW, ALESKANDARANY, MOHAMMED A., RAKHA, EMAD, ELLIS, IAN O., ALI, SIMAK, LI, XIAOXIAN, KRISHNAMURTI, UMA, REID, MICHELLE D., RIDA, PADMASHREE C. G. and ANEJA, RITU, 2016. Retinoic Acid Receptor Alpha Is a Positive Prognostic Biomarker in Triple-Negative Breast Cancer LABORATORY INVESTIGATION. 96, 62A-63A
• GREEN, ANDREW R, SORIA, DANIELE, STEPHEN, JACQUELINE, POWE, DESMOND G, NOLAN, CHRISTOPHER C, KUNKLER, IAN, THOMAS, JEREMY, KERR, GILLIAN R, JACK, WILMA, CAMERON, DAVID, PIPER, TAMMY, BALL, GRAHAM R, GARIBALDI, JONATHAN M, RAKHA, EMAD A, BARTLETT, JOHN MS and ELLIS, IAN O, 2016. Nottingham Prognostic Index Plus: Validation of a clinical decision making tool in breast cancer in an independent series. The journal of pathology. Clinical research. 2(1), 32-40
• NEGM, OLA H., MUFTAH, ABIR A., ALESKANDARANY, MOHAMMED A., HAMED, MOHAMED R., AHMAD, DENA A. J., NOLAN, CHRISTOPHER C., DIEZ-RODRIGUEZ, MARIA, TIGHE, PATRICK J., ELLIS, IAN O., RAKHA, EMAD A. and GREEN, ANDREW R., 2016. Clinical utility of reverse phase protein array for molecular classification of breast cancer BREAST CANCER RESEARCH AND TREATMENT. 155(1), 25-35
• OGDEN, ANGELA, GREEN, ANDREW, ALESKANDARANY, MOHAMMED A., RAKHA, EMAD, ELLIS, IAN O., LI, XIAOXIAN, KRISHNAMURTI, UMA, REID, MICHELLE D., RIDA, PADMASHREE C. G. and ANEJA, RITU, 2016. High HER3-EGFR Score Predicts Aggressive Disease Course in Triple-Negative Breast Cancer MODERN PATHOLOGY. 29, 63A-63A
• GREEN, ANDREW R., SORIA, D., POWE, D. G., NOLAN, C. C., ALESKANDARANY, M., SZASZ, M. A., TOKES, A. M., BALL, G. R., GARIBALDI, J. M., RAKHA, E. A., KULKA, J. and ELLIS, I. O., 2016. Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer (vol 157, pg 65, 2016) BREAST CANCER RESEARCH AND TREATMENT. 159(1),
• TAN, BENJAMIN Y., ACS, GEZA, APPLE, SOPHIA K., BADVE, SUNIL, BLEIWEISS, IRA J., BROGI, EDI, CALVO, JOSE P., DABBS, DAVID J., ELLIS, IAN O., EUSEBI, VINCENZO, FARSHID, GELAREH, FOX, STEPHEN B., ICHIHARA, SHU, LAKHANI, SUNIL R., RAKHA, EMAD A., REIS-FILHO, JORGE S., RICHARDSON, ANDREA L., SAHIN, AYSEGUL, SCHMITT, FERNANDO C., SCHNITT, STUART J., SIZIOPIKOU, KALLIOPI P., SOARES, FERNANDO A., TSE, GARY M., VINCENT-SALOMON, ANNE and PUAY HOON TAN, 2016. Phyllodes tumours of the breast: a consensus review HISTOPATHOLOGY. 68(1), 5-21
• CRAZE, M., JOSEPH, C., SORIA, D., NOLAN, C., GREEN, A., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Molecular Pathology of Low Grade Oestrogen Receptor Positive Breast Cancer: Cues from Immunohistochemistry and Informatics JOURNAL OF PATHOLOGY. 238, S6-S6
• EBERLE, CAREY A., PISCUOGLIO, SALVATORE, RAKHA, EMAD A., NG, CHARLOTTE K. Y., GEYER, FELIPE C., EDELWEISS, MARCIA, SAKR, RITA A., WEIGELT, BRITTA, REIS-FILHO, JORGE S. and ELLIS, IAN O., 2016. Infiltrating epitheliosis of the breast: characterization of histological features, immunophenotype and genomic profile HISTOPATHOLOGY. 68(7), 1030-1039
• RAKHA EA, AGARWAL D, GREEN AR, ASHANKYTY I, ELLIS IO, BALL G and ALASKANDARANY MA, 2016. Prognostic stratification of oestrogen receptor-positive HER2-negative lymph node-negative class of breast cancer. Histopathology. (In Press.)
• TAN BY, ACS G, APPLE SK, BADVE S, BLEIWEISS IJ, BROGI E, CALVO JP, DABBS DJ, ELLIS IO, EUSEBI V, FARSHID G, FOX SB, ICHIHARA S, LAKHANI SR, RAKHA EA, REIS-FILHO JS, RICHARDSON AL, SAHIN A, SCHMITT FC, SCHNITT SJ, SIZIOPIKOU KP, SOARES FA, TSE GM, VINCENT-SALOMON A and TAN PH, 2016. Phyllodes tumours of the breast: a consensus review. Histopathology. 68(1), 5-21
• RAKHA EA, ALESKANDARANY MA, LEE AH and ELLIS IO, 2016. An approach to the diagnosis of spindle cell lesions of the breast. Histopathology. 68(1), 33-44
• GUERINI-ROCCO E, PISCUOGLIO S, NG CK, GEYER FC, DE FILIPPO MR, EBERLE CA, AKRAM M, FUSCO N, ICHIHARA S, SAKR RA, YATABE Y, VINCENT-SALOMON A, RAKHA EA, ELLIS IO, WEN YH, WEIGELT B, SCHNITT SJ and REIS-FILHO JS, 2016. Microglandular adenosis associated with triple-negative breast cancer is a neoplastic lesion of triple-negative phenotype harbouring TP53 somatic mutations. The Journal of pathology. 238(5), 677-88
• LAURINAVICIUS A, PLANCOULAINE B, RASMUSSON A, BESUSPARIS J, AUGULIS R, MESKAUSKAS R, HERLIN P, LAURINAVICIENE A, ABDELHADI MUFTAH AA, MILIGY I, ALESKANDARANY M, RAKHA EA, GREEN AR and ELLIS IO, 2016. Bimodality of intratumor Ki67 expression is an independent prognostic factor of overall survival in patients with invasive breast carcinoma. Virchows Archiv : an international journal of pathology. 468(4), 493-502
• ALESKANDARANY MA, AGARWAL D, NEGM OH, BALL G, ELMOUNA A, ASHANKYTY I, NUGLOZEH E, FAZALUDEEN MF, DIEZ-RODRIGUEZ M, NOLAN CC, TIGHE PJ, GREEN AR, ELLIS IO and RAKHA EA, 2016. The prognostic significance of STAT3 in invasive breast cancer: analysis of protein and mRNA expressions in large cohorts. Breast cancer research and treatment. 156(1), 9-20
• GREEN AR, ALESKANDARANY MA, AGARWAL D, ELSHEIKH S, NOLAN CC, DIEZ-RODRIGUEZ M, MACMILLAN RD, BALL GR, CALDAS C, MADHUSUDAN S, ELLIS IO and RAKHA EA, 2016. MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours. British journal of cancer. 114(8), 917-28
• SHAMANNA RA, LU H, CROTEAU DL, ARORA A, AGARWAL D, BALL G, ALESKANDARANY MA, ELLIS IO, POMMIER Y, MADHUSUDAN S and BOHR VA, 2016. Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer. Oncotarget. 7(12), 13269-84
• GREEN AR, SORIA D, POWE DG, NOLAN CC, ALESKANDARANY M, SZÁSZ MA, TŐKÉS AM, BALL GR, GARIBALDI JM, RAKHA EA, KULKA J and ELLIS IO, 2016. Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer. Breast cancer research and treatment. 157(1), 65-75
• PEREIRA B, CHIN SF, RUEDA OM, VOLLAN HK, PROVENZANO E, BARDWELL HA, PUGH M, JONES L, RUSSELL R, SAMMUT SJ, TSUI DW, LIU B, DAWSON SJ, ABRAHAM J, NORTHEN H, PEDEN JF, MUKHERJEE A, TURASHVILI G, GREEN AR, MCKINNEY S, OLOUMI A, SHAH S, ROSENFELD N, MURPHY L, BENTLEY DR, ELLIS IO, PURUSHOTHAM A, PINDER SE, BØRRESEN-DALE AL, EARL HM, PHAROAH PD, ROSS MT, APARICIO S and CALDAS C, 2016. The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes. Nature communications. 7, 11479
• PEREIRA B, CHIN SF, RUEDA OM, VOLLAN HK, PROVENZANO E, BARDWELL HA, PUGH M, JONES L, RUSSELL R, SAMMUT SJ, TSUI DW, LIU B, DAWSON SJ, ABRAHAM J, NORTHEN H, PEDEN JF, MUKHERJEE A, TURASHVILI G, GREEN AR, MCKINNEY S, OLOUMI A, SHAH S, ROSENFELD N, MURPHY L, BENTLEY DR, ELLIS IO, PURUSHOTHAM A, PINDER SE, BØRRESEN-DALE AL, EARL HM, PHAROAH PD, ROSS MT, APARICIO S and CALDAS C, 2016. Erratum: The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes. Nature communications. 7, 11908
• RAKHA EA, AHMED MA and ELLIS IO, 2016. Papillary carcinoma of the breast: diagnostic agreement and management implications. Histopathology. 69(5), 862-870
• ABDEL-FATAH TM, AGARWAL D, LIU DX, RUSSELL R, RUEDA OM, LIU K, XU B, MOSELEY PM, GREEN AR, POCKLEY AG, REES RC, CALDAS C, ELLIS IO, BALL GR and CHAN SY, 2016. SPAG5 as a prognostic biomarker and chemotherapy sensitivity predictor in breast cancer: a retrospective, integrated genomic, transcriptomic, and protein analysis. The Lancet. Oncology. 17(7), 1004-18
• ALESKANDARANY MA, GREEN AR, ASHANKYTY I, ELMOUNA A, DIEZ-RODRIGUEZ M, NOLAN CC, ELLIS IO and RAKHA EA, 2016. Impact of intratumoural heterogeneity on the assessment of Ki67 expression in breast cancer. Breast cancer research and treatment. 158(2), 287-95
• RAKHA EA, BENNETT RL, COLEMAN D, PINDER SE, ELLIS IO and , 2016. Review of the national external quality assessment (EQA) scheme for breast pathology in the UK. Journal of clinical pathology. (In Press.)
• TAN BY, THIKE AA, ELLIS IO and TAN PH, 2016. Clinicopathologic Characteristics of Solid Papillary Carcinoma of the Breast. The American journal of surgical pathology. 40(10), 1334-42
• GREEN AR, SORIA D, POWE DG, NOLAN CC, ALESKANDARANY M, SZÁSZ MA, TŐKÉS AM, BALL GR, GARIBALDI JM, RAKHA EA, KULKA J and ELLIS IO, 2016. Erratum to: Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer. Breast cancer research and treatment. 159(1), 199
• ALSHAREEDA AT, NEGM OH, ALESKANDARANY MA, GREEN AR, NOLAN C, TIGHHE PJ, MADHUSUDAN S, ELLIS IO and RAKHA EA, 2016. Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response protein. Breast cancer research and treatment. 159(1), 41-53
• GREEN AR, SORIA D, STEPHEN J, POWE DG, NOLAN CC, KUNKLER I, THOMAS J, KERR GR, JACK W, CAMERON D, PIPER T, BALL GR, GARIBALDI JM, RAKHA EA, BARTLETT JM and ELLIS IO, 2016. Nottingham Prognostic Index Plus: Validation of a clinical decision making tool in breast cancer in an independent series. The journal of pathology. Clinical research. 2(1), 32-40
• ALESKANDARANY MA, ABDULJABBAR R, ASHANKYTY I, ELMOUNA A, JERJEES D, ALI S, BULUWELA L, DIEZ-RODRIGUEZ M, CALDAS C, GREEN AR, ELLIS IO and RAKHA EA, 2016. Prognostic significance of androgen receptor expression in invasive breast cancer: transcriptomic and protein expression analysis. Breast cancer research and treatment. 159(2), 215-27
• AGBOOLA AO, EBILI HO, IYAWE VO, BANJO AA, SALAMI BS, RAKHA EA, NOLAN C, ELLIS IO and GREEN AR, 2016. Tumour cell membrane laminin expression is associated with basal-like phenotype and poor survival in Nigerian breast cancer. The Malaysian journal of pathology. 38(2), 83-92
• BESUSPARIS J, PLANCOULAINE B, RASMUSSON A, AUGULIS R, GREEN AR, ELLIS IO, LAURINAVICIENE A, HERLIN P and LAURINAVICIUS A, 2016. Impact of tissue sampling on accuracy of Ki67 immunohistochemistry evaluation in breast cancer. Diagnostic pathology. 11(1), 82
• AHMAD DA, NEGM OH, ALABDULLAH ML, MIRZA S, HAMED MR, BAND V, GREEN AR, ELLIS IO and RAKHA EA, 2016. Clinicopathological and prognostic significance of mitogen-activated protein kinases (MAPK) in breast cancers. Breast cancer research and treatment. 159(3), 457-67
• MUFTAH AA, ALESKANDARANY M, SONBUL SN, NOLAN CC, DIEZ RODRIGUEZ M, CALDAS C, ELLIS IO, GREEN AR and RAKHA EA, 2016. Further Evidence to Support Bimodality of Oestrogen Receptor Expression in Breast Cancer. Histopathology. (In Press.)
• GEYER FC, BERMAN SH, MARCHIÒ C, BURKE KA, GUERINI-ROCCO E, PISCUOGLIO S, NG CK, PAREJA F, WEN HY, HODI Z, SCHNITT SJ, RAKHA EA, ELLIS IO, NORTON L, WEIGELT B and REIS-FILHO JS, 2016. Genetic analysis of microglandular adenosis and acinic cell carcinomas of the breast provides evidence for the existence of a low-grade triple-negative breast neoplasia family. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. (In Press.)
• FUSCO N, GEYER FC, DE FILIPPO MR, MARTELOTTO LG, NG CK, PISCUOGLIO S, GUERINI-ROCCO E, SCHULTHEIS AM, FUHRMANN L, WANG L, JUNGBLUTH AA, BURKE KA, LIM RS, VINCENT-SALOMON A, BAMBA M, MORITANI S, BADVE SS, ICHIHARA S, ELLIS IO, REIS-FILHO JS and WEIGELT B, 2016. Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 29(11), 1292-1305
• PATEL H, ABDULJABBAR R, LAI CF, PERIYASAMY M, HARROD A, GEMMA C, STEEL JH, PATEL N, BUSONERO C, JERJEES D, REMENYI J, SMITH S, GOMM JJ, MAGNANI L, GYŐRFFY B, JONES LJ, FULLER-PACE F, SHOUSHA S, BULUWELA L, RAKHA EA, ELLIS IO, COOMBES RC and ALI S, 2016. Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor-Positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. (In Press.)
• ARORA A, PARVATHANENI S, ALESKANDARANY MA, AGARWAL D, ALI R, ABDEL-FATAH TM, GREEN AR, BALL GR, RAKHA EA, ELLIS IO, SHARMA S and MADHUSUDAN S, 2016. Clinicopathological and functional significance of RECQL1 helicase in sporadic breast cancers. Molecular cancer therapeutics. (In Press.)
• MATHEW J, KARIA R, MORGAN DA, LEE AH, ELLIS IO, ROBERTSON JF and BELLO AM, 2016. Factors influencing local control in patients undergoing breast conservation surgery for ductal carcinoma in situ. Breast (Edinburgh, Scotland). 31, 181-185 (In Press.)
• POWE, DESMOND G., BUCZEK, MAGDALENA E., JOHNSON, CATHERINE, SCHNEIDER, ANNE, VADAKEKOLATHU, JAYAKUMAR, ELLIS, IAN O., POCKLEY, ALAN G., REES, ROBERT C., BALL, GRAHAM R. and REGARD, TARIK, 2016. Cellular pathways regulating the function of MTSS1 in HER2-positive breast cancer INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 38, S57-S57
• JOSEPH, C., RUSSELL, R., CRAZE, M., NOLAN, C., PROVENZANO, E., CALDAS, C., GREEN, A., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. The Prognostic Significance of KRAS-Induced Actin-Interacting Protein (KRAP) Expression in Invasive Breast Cancer JOURNAL OF PATHOLOGY. 240, 16-16
• SONBUL, S. N., PIGERA, M., MUKHERJEE, A., ALESKANDARANY, M. A., GREEN, A. R., DIEZ-RODRIGUEZ, M., JOSEPH, C., NOLAN, C. C., ELLIS, I. O. and RAKHA, E. A., 2016. Ankyrin 3 Protein may Influence DNA-Damage Response Pathways and the Immune Response in Invasive Breast Carcinoma JOURNAL OF PATHOLOGY. 240, 19-19
• MUFTAH, A. A., ALESKANDARANY, M. A., SONBUL, S. N., NOLAN, C. C., RODRIGUEZ, M. DIEZ, CALDAS, C., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2016. Further Evidence to Support that Oestrogen Receptor Expression in Breast Cancer is Bimodal JOURNAL OF PATHOLOGY. 240, 19-19
• OGDEN, ANGELA, GREEN, ANDREW, ALESKANDARANY, MOHAMMED A., RAKHA, EMAD, ELLIS, IAN O., ALI, SIMAK, LI, XIAOXIAN, KRISHNAMURTI, UMA, REID, MICHELLE D., RIDA, PADMASHREE C. G. and ANEJA, RITU, 2016. Retinoic Acid Receptor Alpha Is a Positive Prognostic Biomarker in Triple-Negative Breast Cancer MODERN PATHOLOGY. 29, 62A-63A
• SONBUL, S. N., MUKHERJEE, A., RUSSELL, R., RUEDA, O. M., ALESKANDARANY, M. A., GREEN, A. R., NOLAN, C. C., DIEZ-RODRIGUEZ, M., PROVENZANO, E., CALDAS, C., ELLIS, I. O. and RAKHA, E. A., 2016. Multiple Coagulation Factor Deficiency Protein-2 (MCFD2) as a Potential Prognostic Germ Cell Marker in Invasive Breast Carcinoma: a Transcriptome-Driven Study JOURNAL OF PATHOLOGY. 240, 21-21
• SURRIDGE, R., ALESKANDARANY, M. A., SONBUL, S., ELMOUNA, A., ASHANKYTY, I., NUGLOZEH, E., FAZALUDEEN, M. F., CALDAS, C., DIEZ-RODRIGUEZ, M., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2016. Rho-GTPase Activating-protein 18 (ARHGAP18): A Biomarker Associated with Lymphovascular Invasion in Invasive Breast Cancer JOURNAL OF PATHOLOGY. 240, 24-24
• MILIGY, I., GABER, A., MOHAN, P., NOLAN, C., DIEZ-RODRIGUEZ, M., CRAZE, M., JOSEPH, C., AL-KAABI, M. M., ALESKANDARANY, M. A., MUKHERJEE, A., CHAPMAN, C., MACMILLAN, R. D., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2016. Prognostic Significance of Tumour Infiltrating Lymphocytes in Ductal Carcinoma In Situ JOURNAL OF PATHOLOGY. 240, 26-26
• PAPANASTASIOU, ANASTASIOS D., WEN, HUEI CHI, SCHULTHEIS, ANNE M., NG, CHARLOTTE K. Y., EDELWEISS, MARCIA, PISCUOGLIO, SALVATORE, MARTELOTTO, LUCIANO G., GEYER, FELIPE C., BURKE, KATHLEEN, DE FILIPPO, MARIA ROSARIA, MACEDO, GABRIEL S., VARGA, ZSUZSANNA, RAKHA, EMAD, ELLIS, IAN O., RUBIN, BRIAN P., WEIGELT, BRITTA and REIS-FILHO, JORGE S., 2016. The Mutational Landscape of Breast Adenomyoepitheliomas LABORATORY INVESTIGATION. 96, 64A-64A
• MUKHERJEE, A., RUSSELL, R., RUEDA, O. M., HAMARSHEH, S., CALDAS, C., PROVENZANO, E. and ELLIS, I. O., 2016. Exploring Molecular Portraits Defining Low Grade in Breast Cancer JOURNAL OF PATHOLOGY. 240, 19-19
• OGDEN, ANGELA, GREEN, ANDREW, ALESKANDARANY, MOHAMMED A., RAKHA, EMAD, ELLIS, IAN O., LI, XIAOXIAN, KRISHNAMURTI, UMA, REID, MICHELLE D., RIDA, PADMASHREE C. G. and ANEJA, RITU, 2016. High HER3-EGFR Score Predicts Aggressive Disease Course in Triple-Negative Breast Cancer LABORATORY INVESTIGATION. 96, 63A-63A
• BARUS, N., JOSEPH, C., CRAZE, M., ALIYEVA, T., OJIEGBE, S., NOLAN, C., DIEZ-RODRIGUEZ, M., GREEN, A. R., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Loss of Latent MMP7 Leads to Increased Lympho-Vascular Invasion and Poor Prognosis in Breast Cancer JOURNAL OF PATHOLOGY. 240, 26-26
• CRAZE, M., JOSEPH, C., RUSSELL, R., RUEDA, O. M., PROVENZANO, E., CALDAS, C., GREEN, A. R., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Phosphorylation Status of MED1 Protein Results in Differential Prognosis in Breast Cancer JOURNAL OF PATHOLOGY. 240, 26-26
• RAKHA, E. A., AHMED, M. A. H., LEE, A. H., HODI, Z., ALESKANDARANY, M., COLEMAN, D., BENNETT, R. A., HAWKES, C. and ELLIS, I. O., 2016. Research Studies and Level of Diagnostic Concordance in Breast Pathology: Lessons from the UK EQA Scheme JOURNAL OF PATHOLOGY. 240, 20-20
• BARUS, N., JOSEPH, C., CRAZE, M., PROVENZANO, E., RUSSELL, R., CALDAS, C., GREEN, A. R., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Investigating the Role of CREM Protein in Lymphovascular Invasion in Breast Cancer JOURNAL OF PATHOLOGY. 240, 26-26
• NEGM, O. H., MUFTAH, A. A., ALESKANDARANY, M. A., HAMED, M. R., AHMAD, D. A. J., NOLAN, C. C., RODRIGUEZ, M. D., TIGHE, P. J., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2016. The Merits of Reverse Phase Protein Array for Molecular Classification of Breast Cancer JOURNAL OF PATHOLOGY. 240, 15-15
• CUZICK, J., FORBES, J. F., SESTAK, I., HOWELL, A., BONANNI, B., BUNDRED, N., LEVY, C., VON MINCKWITZ, G., EIERMANN, W., NEVEN, P., STIERER, M., HOLCOMBE, C., COLEMAN, R. E., JONES, L. J. and ELLIS, I., 2016. Anastrozole versus tamoxifen for the prevention of loco-regional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in-situ (IBIS-II DCIS) CANCER RESEARCH. 76,
• GURHAN, S., ALESKANDARANY, M. A., NOLAN, C. C., DIEZ-RODRIGUEZ, M., CARACAPPA, D., MACMILLAN, R. D., MADHUSUDAN, S., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2016. PALB2 is Downregulated in Sporadic Triple Negative Invasive Breast Cancer and is Associated with Poor Prognosis JOURNAL OF PATHOLOGY. 240, 16-16
• ALBANGHALI, M. A., ALESKANDARANY, M. A., RAKHA, E. A., SYED, B. M., GREEN, A. R., NOLAN, C., DIEZ-RODRIGUEZ, M., ELLIS, I. O. and CHEUNG, K. L., 2016. Reporting on Ki67 Expression Utilising Core Needle Biopsy and Surgical Excision Specimens in Older Women with Invasive Breast Cancer JOURNAL OF PATHOLOGY. 240, 24-24
• AL-BAZZ, D. Y., ALESKANDARANY, M. A., NOLAN, C. C., DIEZ-RODRIGUEZ, M., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2016. Phenotypic and Immunophenotypic Characterisation of Recurrent Breast Cancer JOURNAL OF PATHOLOGY. 240, 20-20
• JERJEES, D. A., CHENG, K. W., ALIYEVA, T., GOODING, L., AMOAH-DUODU, A., DIEZ-RODRIGUEZ, M., NOLAN, C. C., ELLIS, I. O., GREEN, A. R., RAKHA, E. A. and ALESKANDARANY, M. A., 2016. Phosphorylated Activating Transcription Factor 2 is Related to Good Prognosis in Invasive Breast Cancer JOURNAL OF PATHOLOGY. 240, 25-25
• SONBUL, S. N., MUKHERJEE, A., ALESKANDARANY, M. A., RUSSELL, R., RUEDA, O., GREEN, A. R., NOLAN, C. C., DIEZ-RODRIGUEZ, M., PROVENZANO, E., CALDAS, C., ELLIS, I. O. and RAKHA, E. A., 2016. Vesicular Transporter Proteins in Invasive Breast Cancer: Clinicopathological Relevance of Synaptosomal-Associated Protein-23 (SNAP23) JOURNAL OF PATHOLOGY. 240, 15-15
• PEREIRA, BERNARD, CHIN, SUET-FEUNG, RUEDA, OSCAR M., VOLLAN, HANS-KRISTIAN MOEN, PROVENZANO, ELENA, BARDWELL, HELEN A., PUGH, MICHELLE, JONES, LINDA, RUSSELL, ROSLIN, SAMMUT, STEPHEN-JOHN, TSUI, DANA W. Y., LIU, BIN, DAWSON, SARAH-JANE, ABRAHAM, JEAN, NORTHEN, HELEN, PEDEN, JOHN F., MUKHERJEE, ABHIK, TURASHVILI, GULISA, GREEN, ANDREW R., MCKINNEY, STEVE, OLOUMI, ARUSHA, SHAH, SOHRAB, ROSENFELD, NITZAN, MURPHY, LEIGH, BENTLEY, DAVID R., ELLIS, IAN O., PURUSHOTHAM, ARNIE, PINDER, SARAH E., BORRESEN-DALE, ANNE-LISE, EARL, HELENA M., PHAROAH, PAUL D., ROSS, MARK T., APARICIO, SAMUEL and CALDAS, CARLOS, 2016. The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes (vol 7, 11479, 2016) NATURE COMMUNICATIONS. 7,
• GEYER, FELIPE C., PISCUOGLIO, SALVATORE, NG, CHARLOTTE K. Y., GUERINI-ROCCO, ELENA, MARCHIO, CATERINA, HODI, ZSOLT, RAKHA, EMAD, ELLIS, IAN O., SCHNITT, STUART, WEIGELT, BRITTA and REIS-FILHO, JORGE S., 2016. Are Microglandular Adenosis and Breast Acinic Cell Carcinomas Related Lesions? LABORATORY INVESTIGATION. 96, 42A-42A
• ALESKANDARANY, M. A., SURRIDGE, R., SONBUL, S., ELMOUNA, A., ASHANKYTY, I., NUGLOZEH, E., FAZALUDEEN, M. F., NOLAN, C. C., DIEZ-RODRIGUEZ, M., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2016. Expression of CUL4A in invasive Breast Cancer: a Biomarker of Good Prognosis Related to Tumour Differentiation JOURNAL OF PATHOLOGY. 240, 20-20
• HAMARSHEH, S., CRAZE, M., JOSEPH, C., PROVENZANO, E., RUSSELL, R., CALDAS, C., GREEN, A. R., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Nostrin as a Marker Related to Low Grade and Better Prognosis in Breast Cancer JOURNAL OF PATHOLOGY. 240, 20-20
• SONBUL, S. N., ALESKANDARANY, M. A., MUKHERJEE, A., GREEN, A. R., MILIGY, I., DIEZ-RODRIGUEZ, M., NOLAN, C. C., ELLIS, I. O. and RAKHA, E. A., 2016. Clinicopathological Impact of C-C Chemokine Receptor Type 7 (CCR7) Protein Expression in Triple Negative Breast Carcinoma (TNBC) JOURNAL OF PATHOLOGY. 240, 27-27
• PALMIERI, C., RUDRARAJU, B., GIANNOUDIS, A., MOORE, D., SHAW, J., CHAN, S., ELLIS, I. O., CALDAS, C., COOMBES, R. C., CARROLL, J. S., ALI, S. and ABDEL-FATAH, T. M. A., 2016. A study of c-Jun N -terminal kinase (JNK) and c-Jun as biomarkers in early breast cancer CANCER RESEARCH. 76,
• JOSEPH, C., CRAZE, M., NOLAN, C., DIEZ-RODRIGUEZ, M., GREEN, A. R., RAKHA, E., ELLIS, I. O. and MUKHERJEE, A., 2016. Subcellular Localisation Specific HOXB13:IL17BR Protein Index Predicts For Poorer Prognosis and Metastatic Progression in Breast Cancer JOURNAL OF PATHOLOGY. 240, 25-25
• ALESKANDARANY, M. A., DIEZ-RODRIGUEZ, M., NUGLOZEH, E., ELMOUNA, A., FAZALUDEEN, M. F., ASHANKYTY, I., MIAN, S., NOLAN, C. C., ELLIS, I. O., GREEN, A. R. and RAKHA, E. A., 2016. Exome Sequencing Identifies MSS51 Mitochondrial Translational Activator as a Putative Metastasis Associated Gene in Invasive Breast Carcinoma JOURNAL OF PATHOLOGY. 240, 12-12
• PANDYA, KINNARI, WYATT, DEBRA, GALLAGHER, BRIAN, SHAH, DEEP, BAKER, ANDREW, BLOODWORTH, JEFFREY, ZLOBIN, ANDREI, PANNUTI, ANTONIO, GREEN, ANDREW, ELLIS, IAN O., FILIPOVIC, ALEKSANDRA, SAGERT, JASON, RANA, AJAY, ALBAIN, KATHY S., MIELE, LUCIO, DENNING, MITCHELL F. and OSIPO, CLODIA, 2016. PKC alpha Attenuates Jagged-1-Mediated Notch Signaling in ErbB-2-Positive Breast Cancer to Reverse Trastuzumab Resistance CLINICAL CANCER RESEARCH. 22(1), 175-186
• HUNT KK, KARAKAS C, HA MJ, BIERNACKA A, YI M, SAHIN A, ADJAPONG O, HORTOBOGYI GN, BONDY ML, THOMPSON PA, CHEUNG KL, ELLIS IO, BACUS S, SYMMANS WF, DO KA and KEYOMARSI K, 2016. Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. (In Press.)
• TOSS MS, PINDER SE, GREEN AR, THOMAS J, MORGAN DA, ROBERTSON JF, ELLIS IO and RAKHA EA, 2016. Breast conservation in ductal carcinoma in situ (DCIS): what defines optimal margins? Histopathology. 70(5), 681-692
• AGBOOLA AO, EBILI HO, IYAWE VO, BANJO AA, SALAMI BA, RAKHA EA, NOLAN CC, ELLIS IO and GREEN AR, 2016. Clinicopathological and molecular characteristics of Ku 70/80 expression in Nigerian breast cancer and its potential therapeutic implications. Pathology, research and practice. 213(1), 27-33
• HUMPHRIES MP, SUNDARA RAJAN S, DROOP A, SULEMAN CAB, CARBONE C, NILSSON C, HONARPISHEH H, CSERNI G, DENT J, FULFORD L, JORDAN LB, JONES JL, KANTHAN R, LITWINIUK M, DI BENEDETTO A, MOTTOLESE M, PROVENZANO E, SHOUSHA S, STEPHENS M, WALKER RA, KULKA J, ELLIS IO, JEFFERY M, THYGESEN HH, CAPPELLETTI V, DAIDONE MG, HEDENFALK IA, FJÄLLSKOG ML, MELISI D, STEAD LF, SHAABAN AM and SPEIRS V, 2016. A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 23(10), 2575-2583
• RAKHA EA, AHMED MA, ALESKANDARANY MA, HODI Z, LEE AH, PINDER SE and ELLIS IO, 2016. Diagnostic concordance of breast pathologists: lessons from the National Health Service Breast Screening Programme Pathology External Quality Assurance Scheme. Histopathology. 70(4), 632-642
• RAKHA EA, COIMBRA ND, HODI Z, JUNEINAH E, ELLIS IO and LEE AH, 2016. Immunoprofile of metaplastic carcinomas of the breast. Histopathology. 70(6), 975-985
• ABDULJABBAR R, AL-KAABI MM, NEGM OH, JERJEES D, MUFTAH AA, MUKHERJEE A, LAI CF, BULUWELA L, ALI S, TIGHE PJ, GREEN A, ELLIS I and RAKHA E, 2015. Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer. Breast cancer research and treatment. 150(3), 511-22
• REA D, FRANCIS A, HANBY AM, SPEIRS V, RAKHA E, SHAABAN A, CHAN S, VINNICOMBE S, ELLIS IO, MARTIN SG, JONES LJ and BERDITCHEVSKI F, 2015. Inflammatory breast cancer: time to standardise diagnosis assessment and management, and for the joining of forces to facilitate effective research. British journal of cancer. (In Press.)
• ABDULJABBAR R, NEGM OH, LAI C, JERJEES DA, AL-KAABI M, HAMED MR, TIGHE PJ, BULUWELA L, MUKHERJEE A, GREEN AR, ALI S, RAKHA EA and ELLIS IO, 2015. Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer. Breast cancer research and treatment. 150(2), 335-46
• RAKHA EA, PIGERA M, SHAABAN A, SHIN SJ, D'ALFONSO T, ELLIS IO and LEE AHS, 2015. National guidelines and level of evidence: comments on some of the new recommendations in the american society of clinical oncology and the college of american pathologists human epidermal growth factor receptor 2 guidelines for breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 33(11), 1301-2
• JERJEES DA, NEGM OH, ALABDULLAH ML, MIRZA S, ALKAABI M, HAMEED MR, ABDULJABBAR R, MUFTAH A, NOLAN CC, GREEN AR, TIGHE PJ, BAND V, ELLIS IO and RAKHA EA, 2015. The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways. Breast cancer research and treatment. 150(1), 91-103
• ALESKANDARANY M, CARACAPPA D, NOLAN CC, MACMILLAN RD, ELLIS IO, RAKHA EA and GREEN AR, 2015. DNA damage response markers are differentially expressed in BRCA-mutated breast cancers. Breast cancer research and treatment. 150(1), 81-90
• AL-KAABI MM, ALSHAREEDA AT, JERJEES DA, MUFTAH AA, GREEN AR, ALSUBHI NH, NOLAN CC, CHAN S, CORNFORD E, MADHUSUDAN S, ELLIS IO and RAKHA EA, 2015. Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response. British journal of cancer. 112(5), 901-11
• PISCUOGLIO S, HODI Z, KATABI N, GUERINI-ROCCO E, MACEDO GS, NG CKY, EDELWEISS M, DE MATTOS-ARRUDA L, WEN HY, RAKHA EA, ELLIS IO, RUBIN BP, WEIGELT B and REIS-FILHO JS, 2015. Are acinic cell carcinomas of the breast and salivary glands distinct diseases? Histopathology. (In Press.)
• ARORA A, ABDEL-FATAH TMA, AGARWAL D, DOHERTY R, MOSELEY PM, ALESKANDARANY MA, GREEN AR, BALL G, ALSHAREEDA AT, RAKHA EA, CHAN SYT, ELLIS IO and MADHUSUDAN S, 2015. Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer. Molecular cancer therapeutics. 14(4), 1057-65
• LEE AHS, RAKHA EA and ELLIS IO, 2015. Brief fixation and hormone receptor expression in breast cancer. The American journal of surgical pathology. 39(3), 425
• GREEN AR, CARACAPPA D, BENHASOUNA AA, ALSHAREEDA A, NOLAN CC, MACMILLAN RD, MADHUSUDAN S, ELLIS IO and RAKHA EA, 2015. Biological and clinical significance of PARP1 protein expression in breast cancer. Breast cancer research and treatment. 149(2), 353-62
• RAKHA EA, PINDER SE, BARTLETT JMS, IBRAHIM M, STARCZYNSKI J, CARDER PJ, PROVENZANO E, HANBY A, HALES S, LEE AHS, ELLIS IO and NATIONAL COORDINATING COMMITTEE FOR BREAST PATHOLOGY, 2015. Updated UK Recommendations for HER2 assessment in breast cancer. Journal of clinical pathology. 68(2), 93-9
• ABDEL-FATAH TMA, MIDDLETON FK, ARORA A, AGARWAL D, CHEN T, MOSELEY PM, PERRY C, DOHERTY R, CHAN S, GREEN AR, RAKHA E, BALL G, ELLIS IO, CURTIN NJ and MADHUSUDAN S, 2015. Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer. Molecular oncology. 9(3), 569-85
• RAKHA EA, TAN PH, VARGA Z, TSE GM, SHAABAN AM, CLIMENT F, VAN DEURZEN CHM, PURNELL D, DODWELL D, CHAN T and ELLIS IO, 2015. Prognostic factors in metaplastic carcinoma of the breast: a multi-institutional study. British journal of cancer. 112(2), 283-9
• RAKHA EA, VARGA Z, ELSHEIK S and ELLIS IO, 2015. High-grade encapsulated papillary carcinoma of the breast: an under-recognized entity. Histopathology. 66(5), 740-6
• NELSON L, MCKEEN HD, MARSHALL A, MULRANE L, STARCZYNSKI J, STORR SJ, LANIGAN F, BYRNE C, ARTHUR K, HEGARTY S, ALI AA, FURLONG F, MCCARTHY HO, ELLIS IO, GREEN AR, RAKHA E, YOUNG L, KUNKLER I, THOMAS J, JACK W, CAMERON D, JIRSTRÖM K, YAKKUNDI A, MCCLEMENTS L, MARTIN SG, GALLAGHER WM, DUNN J, BARTLETT J, O'CONNOR D and ROBSON T, 2015. FKBPL: a marker of good prognosis in breast cancer. Oncotarget. (In Press.)
• AGRAWAL A, ROBERTSON JFR, CHEUNG KL, GUTTERIDGE E, ELLIS IO, NICHOLSON RI and GEE JMW, 2015. Biological effects of fulvestrant on estrogen receptor positive human breast cancer: Short, medium and long-term effects based on sequential biopsies. International journal of cancer. Journal international du cancer.
• ABDEL-FATAH, T. M., MCARDLE, S. E., AGARWAL, D., MOSELEY, P. M., GREEN, A. R., BALL, G. R., POCKLEY, A. G., ELLIS, I. O., REES, R. C. and CHAN, S. Y., 2015. HAGE in triple negative breast cancer (TNBC) is a novel prognostic, predictive and actionable biomarker: A Transcriptomic and protein expression analysis: Clin Cancer Res Clin Cancer Res.
• ALBANGHALI MA, GREEN AR, RAKHA E, ALESKANDARANY MA, NOLAN C, ELLIS IO and CHEUNG KL, 2015. Construction of tissue microarrays from core needle biopsy - a systematic literature review. Histopathology. (In Press.)
• ELEFTHERIOU M, PASCUAL AJ, WHELDON LM, PERRY C, ABAKIR A, ARORA A, JOHNSON AD, AUER DT, ELLIS IO, MADHUSUDAN S and RUZOV A, 2015. 5-Carboxylcytosine levels are elevated in human breast cancers and gliomas. Clinical epigenetics. 7(1), 88
• ALBARAKATI, NADA, ABDEL-FATAH, TAREK M. A., DOHERTY, RACHEL, RUSSELL, ROSLIN, AGARWAL, DEVIKA, MOSELEY, PAUL, PERRY, CHRISTINA, ARORA, ARVIND, ALSUBHI, NOUF, SEEDHOUSE, CLAIRE, RAKHA, EMAD A., GREEN, ANDREW, BALL, GRAHAM, CHAN, STEPHEN, CALDAS, CARLOS, ELLIS, IAN O. and MADHUSUDAN, SRINIVASAN, 2015. Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy MOLECULAR ONCOLOGY. 9(1), 204-217
• REA, D., FRANCIS, A., HANBY, A. M., SPEIRS, V., RAKHA, E., SHAABAN, A., CHAN, S., VINNICOMBE, S., ELLIS, I. O., MARTIN, S. G., JONES, L. J. and BERDITCHEVSKI, F., 2015. Inflammatory breast cancer: time to standardise diagnosis assessment and management, and for the joining of forces to facilitate effective research BRITISH JOURNAL OF CANCER. 112(9), 1613-1615
• NELSON, LAURA, MCKEEN, HAYLEY D., MARSHALL, ANDREA, MULRANE, LAOIGHSE, STARCZYNSKI, JANE, STORR, SARAH J., LANIGAN, FIONA, BYRNE, CHRISTOPHER, ARTHUR, KEN, HEGARTY, SHAUNA, ALI, AHLAM ABDUNNABI, FURLONG, FIONA, MCCARTHY, HELEN O., ELLIS, IAN O., GREEN, ANDREW R., RAKHA, EMAD, YOUNG, LEONIE, KUNKLER, IAN, THOMAS, JEREMY, JACK, WILMA, CAMERON, DAVID, JIRSTROM, KARIN, YAKKUNDI, ANITA, MCCLEMENTS, LANA, MARTIN, STEWART G., GALLAGHER, WILLIAM M., DUNN, JANET, BARTLETT, JOHN, O'CONNOR, DARRAN and ROBSON, TRACY, 2015. FKBPL: a marker of good prognosis in breast cancer ONCOTARGET. 6(14), 12209-12223
• ALSHAREEDA, A. T., NEGM, O. H., GREEN, A. R., NOLAN, C. C., TIGHE, P., ALBARAKATI, N., SULTANA, R., MADHUSUDAN, S., ELLIS, I. O. and RAKHA, E. A., 2015. KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer: Br J Cancer Br J Cancer. 112(12), 1929-37
• ABDULJABBAR, REZVAN, NEGM, OLA H., LAI, CHUN-FUI, JERJEES, DENA A., AL-KAABI, METHAQ, HAMED, MOHAMED R., TIGHE, PATRICK J., BULUWELA, LAKJAYA, MUKHERJEE, ABHIK, GREEN, ANDREW R., ALI, SIMAK, RAKHA, EMAD A. and ELLIS, IAN O., 2015. Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer BREAST CANCER RESEARCH AND TREATMENT. 150(2), 335-346
• ABDULJABBAR, REZVAN, AL-KAABI, METHAQ MUEEN, NEGM, OLA H., JERJEES, DENA, MUFTAH, ABIR A., MUKHERJEE, ABHIK, LAI, CHUN F., BULUWELA, LAKI, ALI, SIMAK, TIGHE, PATRICK J., GREEN, ANDREW, ELLIS, IAN and RAKHA, EMAD, 2015. Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer BREAST CANCER RESEARCH AND TREATMENT. 150(3), 511-522
• JERJEES, DENA A., NEGM, OLA H., ALABDULLAH, M. LAYTH, MIRZA, SAMEER, ALKAABI, METHAQ, HAMEED, MOHAMED R., ABDULJABBAR, REZVAN, MUFTAH, ABIR, NOLAN, CHRIS C., GREEN, ANDREW R., TIGHE, PATRICK J., BAND, VIMLA, ELLIS, IAN O. and RAKHA, EMAD A., 2015. The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways BREAST CANCER RESEARCH AND TREATMENT. 150(1), 91-103
• ALESKANDARANY, M. A., SORIA, D., GREEN, A. R., NOLAN, C., DIEZ-RODRIGUEZ, M., ELLIS, I. O. and RAKHA, E. A., 2015. Markers of progression in early-stage invasive breast cancer: a predictive immunohistochemical panel algorithm for distant recurrence risk stratification: Breast Cancer Res Treat Breast Cancer Res Treat. 151(2), 325-33
• ABDEL-FATAH TM, ARORA A, MOSELEY PM, PERRY C, RAKHA EA, GREEN AR, CHAN SY, ELLIS IO, MADHUSUDAN S., 2015. DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers. Oncotarget. 6(26), 21964-78.
• GUERINI-ROCCO, ELENA, HODI, ZSOLT, PISCUOGLIO, SALVATORE, NG, CHARLOTTE K. Y., RAKHA, EMAD A., SCHULTHEIS, ANNE M., MARCHIO, CATERINA, PAULA, ARNAUD DA CRUZ, DE FILIPPO, MARIA R., MARTELOTTO, LUCIANO G., DE MATTOS-ARRUDA, LETICIA, EDELWEISS, MARCIA, JUNGBLUTH, ACHIM A., FUSCO, NICOLA, NORTON, LARRY, WEIGELT, BRITTA, ELLIS, IAN O. and REIS-FILHO, JORGE S., 2015. The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: an exploratory, hypothesis-generating study JOURNAL OF PATHOLOGY. 237(2), 166-178
• ALESKANDARANY, M. A., NEGM, O. H., TIGHE, P., NOLAN, C., GREEN, A. R., RAKHA, E. A. and ELLIS, I. O., 2015. The Prognostic Significance of STAT3 Expression in Invasive Breast Cancer: an Immunohistochemical and Reverse Phase Protein Array Study JOURNAL OF PATHOLOGY. 237, S32-S32
• ALESKANDARANY, M. A., GREEN, A. R., SAMAKA, R. M., MACMILLAN, R. D., CARACAPPA, D., ELLIS, I. O., DIEZ-RODRIGUEZ, M., RAKHA, E. A., NOLAN, C. and AL-KABBI, M. M., 2015. Cadherin Switch is More Observed in BRCA1 Mutated than the Basal-Like Breast Cancers JOURNAL OF PATHOLOGY. 237, S18-S18
• ELEFTHERIOU, MARIA, PASCUAL, ANA JIMENEZ, WHELDON, LEE M., PERRY, CHRISTINA, ABAKIR, ABDULKADIR, ARORA, ARVIND, JOHNSON, ANDREW D., AUER, DOROTHEE T., ELLIS, IAN O., MADHUSUDAN, SRINIVASAN and RUZOV, ALEXEY, 2015. 5-Carboxylcytosine levels are elevated in human breast cancers and gliomas CLINICAL EPIGENETICS. 7,
• ALESKANDARANY, M. A., GREEN, A. G., DIEZ-RODRIGUEZ, M., NOLAN, C., ELLIS, I. O. and RAKHA, E. A., 2015. Heterogeneity of Ki67 Expression in Different Quadrants and Matched Axillary Nodal Metastases of Invasive Breast Cancer JOURNAL OF PATHOLOGY. 237, S32-S32
• CHRYSANTHOU, E., JOSEPH, C., CRAZE, M., SORIA, D., ELLIS, I. O. and MUKHERJEE, A., 2015. Phenotyping Characterisation of Breast Cancers: the Role of CDC Proteins (2, 42 & 42BPB) JOURNAL OF PATHOLOGY. 237, S31-S31
• YOUSSEF, MANAL M S, PAISH, EMMA C, MURRAY, J CLIFFORD, FARAG, NAGLAA M, SALEH, KHALED and ELLIS, I O, 2015. Tumor Infiltrating T Lymphocytes and Apoptosis in Colorectal Cancer. The Egyptian journal of immunology / Egyptian Association of Immunologists. 22(1), 19-28
• GUERINI-ROCCO, ELENA, PISCUOGLIO, SALVATORE, NG, CHARLOTTE, AKRAM, MUZAFFAR, SAKR, RITA, FUSCO, NICOLA, ICHIHARA, SHU, VINCENT-SALOMON, ANNE, ELLIS, IAN, WEIGELT, BRITTA, WEN, YONG HANNAH, SCHNITT, STUART and REIS-FILHO, JORGE, 2015. Massively Parallel Sequencing Reveals That Microglandular Adenosis Is a Clonal Neoplastic Lesion of Triple-Negative Phenotype MODERN PATHOLOGY. 28, 47A-47A
• GUERINI-ROCCO, ELENA, HODI, ZSOLT, PISCUOGLIO, SALVATORE, NG, CHARLOTTE, SCHULTHEIS, ANNE, MARCHIO, CATERINA, DE MATTOS-ARRUDA, LETICIA, FUSCO, NICOLA, RAKHA, EMAD, WEIGELT, BRITTA, ELLIS, IAN and REIS-FILHO, JORGE, 2015. Massively Parallel Sequencing Analysis of Acinic Cell Carcinoma of the Breast LABORATORY INVESTIGATION. 95, 47A-47A
• ALESKANDARANY, M. A., MIAN, S., DIEZ-RODRIGUEZ, M., NOLAN, C., NUGLOZEH, E., FAZULDEEN, M., ELMOUNA, A., ASHANKYTY, I., GREEN, A. R., RAKHA, E. A. and ELLIS, I. O., 2015. Exome Sequencing of Invasive Breast Cancer Specimens Identifies Discordant Mutational Evolutionary Changes in Invasive Primary Tumour and Axillary Nodal Metastases JOURNAL OF PATHOLOGY. 237, S19-S19
• EBERLE, CAREY, PISCUOGLIO, SALVATORE, RAKHA, EMAD, YAMAGUCHI, RIN, NG, CHARLOTTE, WEIGELT, BRITTA, REIS-FILHO, JORGE and ELLIS, IAN, 2015. Massively Parallel Sequencing Analysis of Infiltrating Epitheliosis of the Breast MODERN PATHOLOGY. 28, 42A-42A
• ABDEL-FATAH, TAREK, IU, DONGXU, AGARWAL, DEVIKA, MOSELEY, PAUL, GREEN, ANDREW, ELLIS, IAN, BALL, GRAHAM and CHAN, STEVEN, 2015. Multicenre Genomic and Protein Expression Analysis Reveals SPAG5 as a Key Oncogene and Biomarker and a Target for Personalized Therapy in Breast Cancer (BC) MODERN PATHOLOGY. 28, 30A-31A
• ABDEL-FATAH, TAREK M. A., LIU, DONG-XU, AGARWAL, DEVIKA, RUSSELL, ROSLIN, RUEDA, OSCAR M., MOSELEY, PAUL M., GREEN, ANDREW R., MUKHERJEE, ABHIK, REIS-FILHO, JORGE, CALDAS, CARLOS, ELLIS, IAN O., BALL, GRAHAM and CHAN, STEVE Y. T., 2015. Mechanistic and clinical analysis of Sperm associated antigen 5 (SPAG5) as a novel prognostic, predictive, actionable gene in Breast Cancer (BC) JOURNAL OF CLINICAL ONCOLOGY. 33(15),
• RAKHA, E. A., TAN, P. H., VARGA, Z., TSE, G. M., SHAABAN, A. M., CLIMENT, F., VAN DEURZEN, C. H. M., PURNELL, D., DODWELL, D., CHAN, T. and ELLIS, I. O., 2015. Prognostic factors in metaplastic carcinoma of the breast: a multi-institutional study BRITISH JOURNAL OF CANCER. 112(2), 283-289
• ABDEL-FATAH, TAREK M. A., MCARDLE, STEPHANIE, AGARWAL, DEVIKA, MOSELEY, PAUL M., GREEN, ANDREW R., BALL, GRAHAM, POCKLEY, A. GRAHAM, ELLIS, IAN O., REES, ROBERT and CHAN, STEVE Y. T., 2015. Transcriptomic and protein expression analysis of helicase antigen (HAGE) in triple negative breast cancer (TNBC) as a novel prognostic and predictive biomarker. JOURNAL OF CLINICAL ONCOLOGY. 33(15),
• MUFTAH, A. A., ALESKANDARANY, M., AL-KAABI, M. M., JERJEES, D. A., ABDULJABBAR, R. F., ALSUBHI, N. H., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2015. Improvement of Ki67 Staining in Breast Cancer (BC) JOURNAL OF PATHOLOGY. 237, S30-S30
• JASANI, BHARAT, CAMPBELL, FIONA, JONES, PHILLAPA, GILBERT, JANE, DOWD, JAMES, MILLER, KEITH, IBRAHIM, MERDOL, ELLIS, IAN, HURLEY, EMMA, FALZON, MARY, PETER, BARRETT-LEE and STARCZYNSKI, JANE, 2015. Audit of the accuracy of immunohistochemical (IHC) testing of HER2 negative status of breast cancer in the United Kingdom CANCER RESEARCH. 75,
• PIGERA, M., LEE, A. H. S., ELLIS, I. O., RAKHA, E. A. and HODI, Z., 2015. Assessment of HER2 Status on Needle Core Biopsy of Breast Cancer: Impact of Histopathological Concordance JOURNAL OF PATHOLOGY. 237, S18-S18
• RAKHA, EMAD A., VARGA, ZSUZSANNA, ELSHEIK, SOMAIA and ELLIS, IAN O., 2015. High-grade encapsulated papillary carcinoma of the breast: an under-recognized entity HISTOPATHOLOGY. 66(5), 740-746
• EBERLE, CAREY, PISCUOGLIO, SALVATORE, RAKHA, EMAD, YAMAGUCHI, RIN, NG, CHARLOTTE, WEIGELT, BRITTA, REIS-FILHO, JORGE and ELLIS, IAN, 2015. Massively Parallel Sequencing Analysis of Infiltrating Epitheliosis of the Breast LABORATORY INVESTIGATION. 95, 42A-42A
• HISCOX, STEPHEN, SMITH, CHRIS, NICHOLSON, ROBERT I., GEE, JULIA, HARRIS, ADRIAN, BLISS, JUDITH, KALAIZAK, ELEFTHERIA, SESTAK, IVANA, DOWSETT, MITCH, CUZICK, JACK, ELLIS, IAN and BARRETT-LEE, PETER, 2015. Nuclear beta-catenin negativity predicts for late relapse in ER plus , tamoxifen-treated breast cancer CANCER RESEARCH. 75,
• PISCUOGLIO, SALVATORE, HODI, ZSOLT, KATABI, NORA, GUERINI-ROCCO, ELENA, MACEDO, GABRIEL S., NG, CHARLOTTE K. Y., EDELWEISS, MARCIA, DE MATTOS-ARRUDA, LETICIA, WEN, HANNAH Y., RAKHA, EMAD A., ELLIS, IAN O., RUBIN, BRIAN P., WEIGELT, BRITTA and REIS-FILHO, JORGE S., 2015. Are acinic cell carcinomas of the breast and salivary glands distinct diseases? HISTOPATHOLOGY. 67(4), 529-537
• AL-KAABI, M. M., ALSHAREEDA, A. T., JERJEES, D. A., MUFTAH, A. A., GREEN, A. R., ALSUBHI, N. H., NOLAN, C. C., CHAN, S., CORNFORD, E., MADHUSUDAN, S., ELLIS, I. O. and RAKHA, E. A., 2015. Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response BRITISH JOURNAL OF CANCER. 112(5), 901-911
• RODEN, DANIEL L, GALLEGOORTEGA , DAVID, LEDGER, ANITA, CHO, CHRISTINA, ALLERDICE, STEPHANIE L, LEE, HEATHER J, VALDES-MORA, FATIMA, YOUNG, ADELAIDE I, LEE, BRIAN Y, KAPLAN, WARREN, SALOMON, ROBERT, PIGGIN, CATHERINE, RABINOVICH, BRIAN, MILLAR, EWAN, OAKES, SAMANTHA R, CHTANOVA, TATYANA, SWARBRICK, ALEXANDER, NAYLOR, MATTHEW, O'TOOLE, SANDRA, GEE, JULIA M, ELLIS, IAN, CLARK, SUSAN J and ORMANDY, CHRISTOPHER J, 2015. GSE58726: The ETS transcription factor Elf5 drives lung metastasis in luminal breast cancer via recruitment of Gr-1+CD11b+ myeloid derived suppressor cells [acute] Gene Expression Omnibus.
• FUSCO, NICOLA, MARTELOTTO, LUCIANO, NG, CHARLOTTE, FUHRMANN, LAETITIA, CYRTA, JOANNA, GUERINI-ROCCO, ELENA, SAKR, RITA, YIM, ELIZABETH, MARCHIO, CATERINA, LIM, RAYMOND, PISCUOGLIO, SALVATORE, VINCENT-SALOMON, ANNE, BADVE, SUNIL, ICHIHARA, SHU, ELLIS, IAN, REIS-FILHO, JORGE and WEIGELT, BRITTA, 2015. Genetic Events in the Progression of Adenoid Cystic Carcinomas of the Breast To High-Grade Triple-Negative Breast Cancers MODERN PATHOLOGY. 28, 45A-45A
• SONBUL, S. N., MUKHERJEE, A., RUSSELL, R., RUEDA, O. M., ALESKANDARANY, M., GREEN, A. R., PROVENZANO, E., CALDAS, C., ELLIS, I. O. and RAKHA, E. A., 2015. Exploring Molecular Mechanisms Underlying Lymphovascular Invasion in Breast Cancer JOURNAL OF PATHOLOGY. 237, S19-S19
• RODEN, DANIEL L, GALLEGOORTEGA , DAVID, LEDGER, ANITA, CHO, CHRISTINA, ALLERDICE, STEPHANIE L, LEE, HEATHER J, VALDES-MORA, FATIMA, YOUNG, ADELAIDE I, LEE, BRIAN Y, KAPLAN, WARREN, SALOMON, ROBERT, PIGGIN, CATHERINE, RABINOVICH, BRIAN, MILLAR, EWAN, OAKES, SAMANTHA R, CHTANOVA, TATYANA, SWARBRICK, ALEXANDER, NAYLOR, MATTHEW, O'TOOLE, SANDRA, GEE, JULIA M, ELLIS, IAN, CLARK, SUSAN J and ORMANDY, CHRISTOPHER J, 2015. GSE58728: The ETS transcription factor Elf5 drives lung metastasis in luminal breast cancer via recruitment of Gr-1+CD11b+ myeloid derived suppressor cells [chronic] Gene Expression Omnibus.
• GREEN, ANDREW R., SORIA, DANIEL, STEPHEN, JACQUELINE, POWE, DESMOND G., NOLAN, CHRISTOPHER C., KUNKLER, IAN, THOMAS, JEREMY, KERR, GILL, JACK, WILMA, CAMRERON, DAVID, PIPER, TAMMY, BALL, GRAHAM R., GARIBALDI, JONATHAN M., RAKHA, EMAD A., BARTLETT, JOHN MS and ELLIS, IAN O., 2015. Nottingham prognostic index plus (NPI plus ): Validation of the modern clinical decision making tool in breast cancer CANCER RESEARCH. 75,
• GREEN, A. R., SORIA, D., STEPHEN, J., POWE, D. G., NOLAN, C. C., KUNKLER, I., THOMAS, J., KERR, G. R., JACK, W., CAMERON, D., PIPER, T., BALL, G. R., GARIBALDI, J. M., RAKHA, E. A., BARLETT, J. M. S. and ELLIS, I. O., 2015. Nottingham Prognostic Index Plus (NPI plus ): Validation of the Modern Clinical Decision Making Tool in Breast Cancer in an Independent Series JOURNAL OF PATHOLOGY. 237, S31-S31
• GREEN, A. R., ALESKANDARANY, M. A., EL-SHEIKH, S., NOLAN, C. C., MACMILLAN, R. D., CALDAS, C., MADHUSUDAN, S., ELLIS, I. O. and RAKHA, E. A., 2015. c-Myc Function is Associated with Specific Molecular Subtypes of Breast Cancer and Confers Resistance to Endocrine Therapy but not Chemotherapy JOURNAL OF PATHOLOGY. 237, S19-S19
• TAN, PUAY HOON, SCHNITT, STUART J., VAN DE VIJVER, MARC J., ELLIS, IAN O. and LAKHANI, SUNIL R., 2015. Papillary and neuroendocrine breast lesions: the WHO stance HISTOPATHOLOGY. 66(6), 761-770
• JERJEES, D. A., NEGM, O. H., ALABDULLAH, M. L., ALESKANDARANY, M., MIRZA, S., GREEN, A. R., TIGHE, P. J., BAND, V., ELLIS, I. O. and RAKHA, E. A., 2015. Mitogen Activated Protein Kinase Signalling Proteins are Associated with Good Prognosis in Breast Cancer and are Mainly Related to Estrogen Receptor JOURNAL OF PATHOLOGY. 237, S18-S18
• GUERINI-ROCCO, ELENA, HODI, ZSOLT, PISCUOGLIO, SALVATORE, NG, CHARLOTTE, SCHULTHEIS, ANNE, MARCHIO, CATERINA, DE MATTOS-ARRUDA, LETICIA, FUSCO, NICOLA, RAKHA, EMAD, WEIGELT, BRITTA, ELLIS, IAN and REIS-FILHO, JORGE, 2015. Massively Parallel Sequencing Analysis of Acinic Cell Carcinoma of the Breast MODERN PATHOLOGY. 28, 47A-47A
• JOSEPH, C., CRAZE, M., SORIA, D., ELLIS, I. O. and MUKHERJEE, A., 2015. Role of Mitotic Checkpoint Proteins (BUB Family) in Breast Cancer JOURNAL OF PATHOLOGY. 237, S31-S31
• RAKHA, EMAD A, PIGERA, MARIAN, SHAABAN, ABEER, SHIN, SANDRA J, D'ALFONSO, TIMOTHY, ELLIS, IAN O and LEE, ANDREW H S, 2015. National guidelines and level of evidence: comments on some of the new recommendations in the American Society of Clinical Oncology and the College of American Pathologists human epidermal growth factor receptor 2 guidelines for breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 33(11), 1301-2
• ABDEL-FATAH, TAREK, LU, DONGXU, AGARWAL, DEVIKA, MOSELEY, PAUL, GREEN, ANDREW, ELLIS, IAN, BALL, GRAHAM and CHAN, STEVEN, 2015. Multicenre Genomic and Protein Expression Analysis Reveals SPAG5 as a Key Oncogene and Biomarker and a Target for Personalized Therapy in Breast Cancer (BC) LABORATORY INVESTIGATION. 95, 30A-31A
• SYED, B. M., GREEN, A. R., MORGAN, D. A. L., ELLIS, I. O. and CHEUNG, K. L., 2015. Biological explanation of the histological grade - older versus younger women with early operable primary breast cancer FUTURE ONCOLOGY. 11(4), 18-19
• STEBBING, J., ZHANG, H., XU, Y., LIT, L. C., GREEN, A. R., GROTHEY, A., LOMBARDO, Y., PERIYASAMY, M., BLIGHE, K., ZHANG, W., SHAW, J. A., ELLIS, I. O., LENZ, H. J. and GIAMAS, G., 2015. KSR1 regulates BRCA1 degradation and inhibits breast cancer growth ONCOGENE. 34(16), 2103-2114
• VOLLAN, HANS KRISTIAN MOEN, RUEDA, OSCAR M., CHIN, SUET-FEUNG, CURTIS, CHRISTINA, TURASHUILI, GULISA, SHAH, SOHRAB, LINGJAERDE, OLE CHRISTIAN, YUAN, YINYIN, NG, CHARLOTTE K., DUNNING, MARK J., DICKS, ED, PROVENZANO, ELENA, SAMMUT, STEPHEN, MCKINNEY, STEVEN, ELLIS, IAN O., PINDER, SARAH, PURUSHOTHAM, ARNIE, MURPHY, LEIGH C., KRISTENSEN, VESSELA N., BRENTON, JAMES D., PHAROAH, PAUL D. P., BORRESEN-DALE, ANNE-LISE, APARICIO, SAMUEL and CALDAS, CARLOS, 2015. A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer MOLECULAR ONCOLOGY. 9(1), 115-127
• ONG, CHRISTY C., GIERKE, SARAH, PITT, CAMERON, SAGOLLA, MEREDITH, CHENG, CHRISTINE K., ZHOU, WEI, JUBB, ADRIAN M., STRICKLAND, LAURA, SCHMIDT, MAIKE, DURON, SERGIO G., CAMPBELL, DAVID A., ZHENG, WEI, DEHDASHTI, SEAMEEN, SHEN, MIN, YANG, NORA, BEHNKE, MARK L., HUANG, WENWEI, MCKEW, JOHN C., CHERNOFF, JONATHAN, FORREST, WILLIAM F., HAVERTY, PETER M., CHIN, SUET-FEUNG, RAKHA, EMAD A., GREEN, ANDREW R., ELLIS, IAN O., CALDAS, CARLOS, O'BRIEN, THOMAS, FRIEDMAN, LORI S., KOEPPEN, HARTMUT, RUDOLPH, JOACHIM and HOEFLICH, KLAUS P., 2015. Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents BREAST CANCER RESEARCH. 17,
• CRAZE, M., JOSEPH, C., RUSSEL, R., RUEDA, O. M., PROVENZANO, E., CALDAS, C., ELLIS, I. O. and MUKHERJEE, A., 2015. SOCS2 as a Marker Related to Low Grade and Tumour Morphology in Breast Cancer JOURNAL OF PATHOLOGY. 237, S13-S13
• FUSCO, NICOLA, MARTELOTTO, LUCIANO, NG, CHARLOTTE, FUHRTNANN, LACTITIA, CYRTA, JOANNA, GUERINI-ROCCO, ELENA, SAKR, RITA, KM, ELIZABETH, MARCHIO, CATERINA, LIM, RAYMOND, PISCUOGLIO, SALVATORE, VINCENT-SALOMON, ANNE, BADVE, SSNIL, ICHIHARA, SHU, ELLIS, IAN, REIS-FILHO, JORGE and WEIGELT, BRITTA, 2015. Genetic Events in the Progression of Adenoid Cystic Carcinomas of the Breast To High-Grade Triple-Negative Breast Cancers LABORATORY INVESTIGATION. 95, 45A-45A
• CRAZE, M., JOSEPH, C., NOLAN, C., GREEN, A., RAKHA, E. A., ELLIS, I. O. and MUKHERJEE, A., 2015. Molecular Pathways Involved in Lymphovascular Invasion: A Biomarker Driven Approach JOURNAL OF PATHOLOGY. 237, S17-S17
• MACNAMARA, O., JOSEPH, C., CRAZE, M., RAKHA, E. A., RUSSELL, R., RUEDA, O. M., PROVENZANO, E., CALDAS, C., ELLIS, I. O. and MUKHERJEE, A., 2015. MED7 in Breast Cancer: Relationship to Grade and Lymphovascular Invasion JOURNAL OF PATHOLOGY. 237, S31-S31
• MUFTAH, A. A., NEGM, O. H., ALESKANDARANY, M., AL-KAABI, M. M., JERJEES, D. A., ELLIS, I. O., RAKHA, E. A. and GREEN, A. R., 2015. Successful Alignment of Macrodissected FFPE Tissue to Nottingham Prognostic Index Plus (NPI plus ) Classes Using RPPA Technology JOURNAL OF PATHOLOGY. 237, S30-S30
• ABDEL-FATAH, TAREK M., BALL, GRAHAM, LEE, ANDREW H. S., PINDER, SARAH, MACMILAN, R. DOUGLAS, CORNFORD, ELEANOR, MOSELEY, PAUL M., SILVERMAN, RAFAEL, PRICE, JAMES, LATHAM, BRUCE, PALMER, DAVID, CHAN, ARLENE, ELLIS, IAN O. and CHAN, STEPHEN Y. T., 2015. Nottingham Clinico-Pathological Response Index (NPRI) after Neoadjuvant Chemotherapy (Neo-ACT) Accurately Predicts Clinical Outcome in Locally Advanced Breast Cancer CLINICAL CANCER RESEARCH. 21(5), 1052-1062
• ALBANGHALI, M. A., ALESKANDARANY, M. A., SYED, B. M., GREEN, A. R., RAKHA, E. A., ELLIS, I. O. and CHEUNG, K. L., 2015. Accuracy of core needle biopsy in determining histological grade and type of primary breast cancer in older women FUTURE ONCOLOGY. 11(4), 20-20
• ONG CC, GIERKE S, PITT C, SAGOLLA M, CHENG CK, ZHOU W, JUBB AM, STRICKLAND L, SCHMIDT M, DURON SG, CAMPBELL DA, ZHENG W, DEHDASHTI S, SHEN M, YANG N, BEHNKE ML, HUANG W, MCKEW JC, CHERNOFF J, FORREST WF, HAVERTY PM, CHIN SF, RAKHA EA, GREEN AR, ELLIS IO, CALDAS C, O'BRIEN T, FRIEDMAN LS, KOEPPEN H, RUDOLPH J and HOEFLICH KP, 2015. Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents. Breast cancer research : BCR. 17, 59
• ALESKANDARANY MA, SORIA D, GREEN AR, NOLAN C, DIEZ-RODRIGUEZ M, ELLIS IO and RAKHA EA, 2015. Markers of progression in early-stage invasive breast cancer: a predictive immunohistochemical panel algorithm for distant recurrence risk stratification. Breast cancer research and treatment. 151(2), 325-33
• ALSHAREEDA AT, NEGM OH, GREEN AR, NOLAN CC, TIGHE P, ALBARAKATI N, SULTANA R, MADHUSUDAN S, ELLIS IO and RAKHA EA, 2015. KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer. British journal of cancer. 112(12), 1929-37
• GUERINI-ROCCO E, HODI Z, PISCUOGLIO S, NG CK, RAKHA EA, SCHULTHEIS AM, MARCHIÒ C, DA CRUZ PAULA A, DE FILIPPO MR, MARTELOTTO LG, DE MATTOS-ARRUDA L, EDELWEISS M, JUNGBLUTH AA, FUSCO N, NORTON L, WEIGELT B, ELLIS IO and REIS-FILHO JS, 2015. The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: an exploratory, hypothesis-generating study. The Journal of pathology. 237(2), 166-78
• RAKHA EA, ALESKANDARANY MA, SAMAKA RM, HODI Z, LEE AH and ELLIS IO, 2015. Pleomorphic adenoma-like tumour of the breast. Histopathology. 68(3), 405-10
• MAGNANI L, PATTEN DK, NGUYEN VT, HONG SP, STEEL JH, PATEL N, LOMBARDO Y, FARONATO M, GOMES AR, WOODLEY L, PAGE K, GUTTERY D, PRIMROSE L, FERNANDEZ GARCIA D, SHAW J, VIOLA P, GREEN A, NOLAN C, ELLIS IO, RAKHA EA, SHOUSHA S, LAM EW, GYŐRFFY B, LUPIEN M and COOMBES RC, 2015. The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer. Oncotarget. 6(26), 21878-91
• ABDEL-FATAH TM, MCARDLE SE, AGARWAL D, MOSELEY PM, GREEN AR, BALL GR, POCKLEY AG, ELLIS IO, REES RC and CHAN SY, 2015. HAGE in Triple-Negative Breast Cancer Is a Novel Prognostic, Predictive, and Actionable Biomarker: A Transcriptomic and Protein Expression Analysis. Clinical cancer research : an official journal of the American Association for Cancer Research. 22(4), 905-14
• ABDEL-FATAH TM, ARORA A, MOSELEY PM, PERRY C, RAKHA EA, GREEN AR, CHAN SY, ELLIS IO and MADHUSUDAN S, 2015. DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers. Oncotarget. 6(26), 21964-78
• MUKHERJEE A, JOSEPH C, CRAZE M, CHRYSANTHOU E and ELLIS IO, 2015. The role of BUB and CDC proteins in low-grade breast cancers. Lancet (London, England). 385 Suppl 1, S72
• RAKHA EA, LEE AH, SHEERAN R, ABBOSH C, HODI Z, MERCHANT W, ELLIS IO and SHAABAN AM, 2015. Breast Neoplasms with Dermal Analogue Differentiation (Mammary Cylindroma): Report of 3 Cases and a Proposal for a New Terminology. Pathobiology : journal of immunopathology, molecular and cellular biology. 82(3-4), 172-8
• PANDYA K, WYATT D, GALLAGHER B, SHAH D, BAKER A, BLOODWORTH J, ZLOBIN A, PANNUTI A, GREEN A, ELLIS IO, FILIPOVIC A, SAGERT J, RANA A, ALBAIN KS, MIELE L, DENNING MF and OSIPO C, 2015. PKCα Attenuates Jagged-1-Mediated Notch Signaling in ErbB-2-Positive Breast Cancer to Reverse Trastuzumab Resistance. Clinical cancer research : an official journal of the American Association for Cancer Research. 22(1), 175-86
• ZWART W, FLACH KD, RUDRARAJU B, ABDEL-FATAH TM, GOJIS O, CANISIUS S, MOORE D, NEVEDOMSKAYA E, OPDAM M, DROOG M, HOFLAND I, CHAN S, SHAW J, ELLIS IO, COOMBES RC, CARROLL JS, ALI S and PALMIERI C, 2015. SRC3 Phosphorylation at Serine 543 Is a Positive Independent Prognostic Factor in ER-Positive Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 22(2), 479-91
• DEB R, JENKINS JA, ROWLANDS D, ELLIS IO and LEE AH, 2015. National survey of B1 and B2 reporting of breast needle core biopsies. Journal of clinical pathology. 69(3), 271-4
• ALSUBHI N, MIDDLETON F, ABDEL-FATAH TM, STEPHENS P, DOHERTY R, ARORA A, MOSELEY PM, CHAN SY, ALESKANDARANY MA, GREEN AR, RAKHA EA, ELLIS IO, MARTIN SG, CURTIN NJ and MADHUSUDAN S, 2015. Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancer. Molecular oncology. 10(2), 213-23
• LAURINAVICIUS A, GREEN AR, LAURINAVICIENE A, SMAILYTE G, OSTAPENKO V, MESKAUSKAS R and ELLIS IO, 2015. Ki67/SATB1 ratio is an independent prognostic factor of overall survival in patients with early hormone receptor-positive invasive ductal breast carcinoma. Oncotarget. 6(38), 41134-45
• ARORA A, ABDEL-FATAH TM, AGARWAL D, DOHERTY R, CROTEAU DL, MOSELEY PM, HAMEED K, GREEN A, ALESKANDARANY MA, RAKHA EA, PATTERSON K, BALL G, CHAN SY, ELLIS IO, BOHR VA, BRYANT HE and MADHUSUDAN S, 2015. Clinicopathological and prognostic significance of RECQL5 helicase expression in breast cancers. Carcinogenesis. 37(1), 63-71
• NEGM OH, MUFTAH AA, ALESKANDARANY MA, HAMED MR, AHMAD DA, NOLAN CC, DIEZ-RODRIGUEZ M, TIGHE PJ, ELLIS IO, RAKHA EA and GREEN AR, 2015. Clinical utility of reverse phase protein array for molecular classification of breast cancer. Breast cancer research and treatment. 155(1), 25-35
• FORBES JF, SESTAK I, HOWELL A, BONANNI B, BUNDRED N, LEVY C, VON MINCKWITZ G, EIERMANN W, NEVEN P, STIERER M, HOLCOMBE C, COLEMAN RE, JONES L, ELLIS I, CUZICK J and , 2015. Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): a double-blind, randomised controlled trial. Lancet (London, England). 387(10021), 866-73
• GALLEGO-ORTEGA D, LEDGER A, RODEN DL, LAW AM, MAGENAU A, KIKHTYAK Z, CHO C, ALLERDICE SL, LEE HJ, VALDES-MORA F, HERRMANN D, SALOMON R, YOUNG AI, LEE BY, SERGIO CM, KAPLAN W, PIGGIN C, CONWAY JR, RABINOVICH B, MILLAR EK, OAKES SR, CHTANOVA T, SWARBRICK A, NAYLOR MJ, O'TOOLE S, GREEN AR, TIMPSON P, GEE JM, ELLIS IO, CLARK SJ and ORMANDY CJ, 2015. ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells. PLoS biology. 13(12), e1002330
• PU X, STORR SJ, AHMAD NS, CHAN SY, MOSELEY PM, TELEVANTOU D, CRESTI N, BODDY A, ELLIS IO and MARTIN SG, 2015. Calpain-1 is associated with adverse relapse free survival in breast cancer: a confirmatory study. Histopathology. 68(7), 1021-9
• EBERLE CA, PISCUOGLIO S, RAKHA EA, NG CK, GEYER FC, EDELWEISS M, SAKR RA, WEIGELT B, REIS-FILHO JS and ELLIS IO, 2015. Infiltrating epitheliosis of the breast: characterization of histological features, immunophenotype and genomic profile. Histopathology. 68(7), 1030-9
• RAKHA EA, PIGERA M, SHIN SJ, D'ALFONSO T, ELLIS IO and LEE AH, 2015. Human epidermal growth factor receptor 2 testing in invasive breast cancer: should histological grade, type and oestrogen receptor status influence the decision to repeat testing? Histopathology. 69(1), 20-4
• RAKHA EA, BADVE S, EUSEBI V, REIS-FILHO JS, FOX SB, DABBS DJ, DECKER T, HODI Z, ICHIHARA S, LEE AH, PALACIOS J, RICHARDSON AL, VINCENT-SALOMON A, SCHMITT FC, TAN PH, TSE GM and ELLIS IO, 2015. Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management. Histopathology. 68(1), 45-56
• ARORA A, AGARWAL D, ABDEL-FATAH TM, LU H, CROTEAU DL, MOSELEY P, ALESKANDARANY MA, GREEN AR, BALL G, RAKHA EA, CHAN SY, ELLIS IO, WANG LL, ZHAO Y, BALAJEE AS, BOHR VA and MADHUSUDAN S, 2015. RECQL4 helicase has oncogenic potential in sporadic breast cancers. The Journal of pathology. 238(4), 495-501
• YOUSSEF MM, PAISH EC, MURRAY JC, FARAG NM, SALEH K and ELLIS IO, 2015. Tumor Infiltrating T Lymphocytes and Apoptosis in Colorectal Cancer. The Egyptian journal of immunology. 22(1), 19-28
• ALSHAREEDA AT, NEGM OH, GREEN AR, NOLAN C, TIGHE P, ALBARAKATI N, SULTANA R, MADHUSUDAN S, ELLIS IO and RAKHA EA, 2014. SUMOylation proteins in breast cancer. Breast cancer research and treatment. 144(3), 519-30
• ABDEL-FATAH TMA, RUSSELL R, AGARWAL D, MOSELEY P, ABAYOMI MA, PERRY C, ALBARAKATI N, BALL G, CHAN S, CALDAS C, ELLIS IO and MADHUSUDAN S, 2014. DNA polymerase β deficiency is linked to aggressive breast cancer: A comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohorts. Molecular oncology. 8(3), 520-32
• ABDEL-FATAH TMA, PERRY C, MOSELEY P, JOHNSON K, ARORA A, CHAN S, ELLIS IO and MADHUSUDAN S, 2014. Clinicopathological significance of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in oestrogen-receptor-positive breast cancer. Breast cancer research and treatment. 143(3), 411-21
• SYED BM, GREEN AR, ELLIS IO and CHEUNG KL, 2014. Human epidermal growth receptor-2 overexpressing early operable primary breast cancers in older (>=70 years) women: biology and clinical outcome in comparison with younger (<70 years) patients. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 25(4), 837-42
• SYED BM, GREEN AR, NOLAN CC, MORGAN DAL, ELLIS IO and CHEUNG K, 2014. Biological characteristics and clinical outcome of triple negative primary breast cancer in older women - comparison with their younger counterparts. PloS one. 9(7), e100573
• MATHEW J, LEE S, SYED BM, MORGAN DAL, ELLIS IO and CHEUNG KL, 2014. A study of ductal versus non-ductal invasive breast carcinomas in older women: long-term clinical outcome and comparison with their younger counterparts. Breast cancer research and treatment. (In Press.)
• ALBARAKATI N, ABDEL-FATAH TMA, DOHERTY R, RUSSELL R, AGARWAL D, MOSELEY P, PERRY C, ARORA A, ALSUBHI N, SEEDHOUSE C, RAKHA EA, GREEN A, BALL G, CHAN S, CALDAS C, ELLIS IO and MADHUSUDAN S, 2014. Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy. Molecular oncology. 9(1), 204-17
• ABDEL-FATAH TM, PERRY C, ARORA A, THOMPSON N, DOHERTY R, MOSELEY PM, GREEN AR, CHAN SY, ELLIS IO and MADHUSUDAN S, 2014. Is there a role for base excision repair in estrogen driven breast cancers? Antioxidants & redox signaling. (In Press.)
• ABDEL-FATAH T, ARORA A, AGARWAL D, MOSELEY P, PERRY C, THOMPSON N, GREEN AR, RAKHA E, CHAN S, BALL G, ELLIS IO and MADHUSUDAN S, 2014. Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers. Breast cancer research and treatment. 146(2), 309-20
• ABDEL-FATAH TMA, RUSSELL R, ALBARAKATI N, MALONEY DJ, DORJSUREN D, RUEDA OM, MOSELEY P, MOHAN V, SUN H, ABBOTTS R, MUKHERJEE A, AGARWAL D, ILLUZZI JL, JADHAV A, SIMEONOV A, BALL G, CHAN S, CALDAS C, ELLIS IO, WILSON DM and MADHUSUDAN S, 2014. Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer. Molecular oncology. (In Press.)
• ALESKANDARANY MA, NEGM OH, GREEN AR, AHMED MAH, NOLAN CC, TIGHE PJ, ELLIS IO and RAKHA EA, 2014. Epithelial mesenchymal transition in early invasive breast cancer: an immunohistochemical and reverse phase protein array study. Breast cancer research and treatment. 145(2), 339-48
• MOHAMMED RA, MENON S, MARTIN SG, GREEN AR, PAISH EC and ELLIS IO, 2014. Prognostic significance of lymphatic invasion in lymph node-positive breast carcinoma: findings from a large case series with long-term follow-up using immunohistochemical endothelial marker. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 27(12), 1568-77
• ZHANG Y, STORR SJ, JOHNSON K, GREEN AR, RAKHA EA, ELLIS IO, MORGAN DAL and MARTIN SG, 2014. Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basal-like breast cancer treated with radiotherapy. Oncotarget. 5(24), 12936-12949
• DAVIS J, MARTIN SG, PATEL PM, GREEN AR, RAKHA EA, ELLIS IO and STORR SJ, 2014. Low calpain-9 is associated with adverse disease-specific survival following endocrine therapy in breast cancer. BMC cancer. 14(1), 995-1003
• WISHART GC, RAKHA E, GREEN A, ELLIS I, ALI HR, PROVENZANO E, BLOWS FM, CALDAS C and PHAROAH PDP, 2014. Inclusion of KI67 significantly improves performance of the PREDICT prognostication and prediction model for early breast cancer. BMC cancer. 14, 908
• ABDEL-FATAH TMA, ARORA A, ALSUBHI N, AGARWAL D, MOSELEY PM, PERRY C, DOHERTY R, CHAN SYT, GREEN AR, RAKHA E, BALL G, ELLIS IO and MADHUSUDAN S, 2014. Clinicopathological significance of ATM-Chk2 expression in sporadic breast cancers: a comprehensive analysis in large cohorts. Neoplasia (New York, N.Y.). 16(11), 982-91
• KONG K, ZAABAR F, RAKHA E, ELLIS I, KOLOYDENKO A and NOTINGHER I, 2014. Towards intra-operative diagnosis of tumours during breast conserving surgery by selective-sampling Raman micro-spectroscopy. Physics in medicine and biology. 59(20), 6141-52
• JERJEES DA, ALABDULLAH M, ALKAABI M, ABDULJABBAR R, MUFTAH A, NOLAN C, GREEN AR, ELLIS IO and RAKHA EA, 2014. ERK1/2 is related to oestrogen receptor and predicts outcome in hormone-treated breast cancer. Breast cancer research and treatment. 147(1), 25-37
• ALI HR, PROVENZANO E, DAWSON S, BLOWS FM, LIU B, SHAH M, EARL HM, POOLE CJ, HILLER L, DUNN JA, BOWDEN SJ, TWELVES C, BARTLETT JMS, MAHMOUD SMA, RAKHA E, ELLIS IO, LIU S, GAO D, NIELSEN TO, PHAROAH PDP and CALDAS C, 2014. Association between CD8+ T-cell infiltration and breast cancer survival in 12,439 patients. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 25(8), 1536-43
• AGBOOLA AOJ, BANJO AAF, ANUNOBI CC, AYOADE BA, DEJI-AGBOOLA AM, MUSA AA, ABDEL-FATAH T, NOLAN CC, RAKHA EA, ELLIS IO and GREEN AR, 2014. Molecular profiling of breast cancer in Nigerian women identifies an altered p53 pathway as a major mechanism underlying its poor prognosis compared with British counterpart. The Malaysian journal of pathology. 36(1), 3-17
• JERJEES DA, ALABDULLAH M, GREEN AR, ALSHAREEDA A, MACMILLAN RD, ELLIS IO and RAKHA EA, 2014. Prognostic and biological significance of proliferation and HER2 expression in the luminal class of breast cancer. Breast cancer research and treatment. 145(2), 317-30
• GREEN AR, BARROS FFT, ABDEL-FATAH TMA, MOSELEY P, NOLAN CC, DURHAM AC, RAKHA EA, CHAN S and ELLIS IO, 2014. HER2/HER3 heterodimers and p21 expression are capable of predicting adjuvant trastuzumab response in HER2+ breast cancer. Breast cancer research and treatment. 145(1), 33-44
• BARROS FFT, ABDEL-FATAH TMA, MOSELEY P, NOLAN CC, DURHAM AC, RAKHA EA, CHAN S, ELLIS IO and GREEN AR, 2014. Characterisation of HER heterodimers in breast cancer using in situ proximity ligation assay. Breast cancer research and treatment. 144(2), 273-85
• RAKHA EA, STARCZYNSKI J, LEE AHS and ELLIS IO, 2014. The updated ASCO/CAP guideline recommendations for HER2 testing in the management of invasive breast cancer: a critical review of their implications for routine practice. Histopathology. 64(5), 609-15
• RAKHA EA and ELLIS IO, 2014. Breast cancer: updated guideline recommendations for HER2 testing. Nature reviews. Clinical oncology. 11(1), 8-9
• AGBOOLA AOJ, MUSA AA, AYOADE BA, BANJO AA, ANUNOBI CC, DEJI-AGBOOLA AM, RAKHA EA, NOLAN C, ELLIS IO and GREEN AR, 2014. Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women. Pathology, research and practice. 210(1), 10-7
• AGBOOLA A, MUSA A, BANJO A, AYOADE B, DEJI-AGBOOLA M, NOLAN C, RAKHA E, ELLIS I and GREEN A, 2014. PIASγ expression in relation to clinicopathological, tumour factors and survival in indigenous black breast cancer women. Journal of clinical pathology. 67(4), 301-6
• HO-YEN CM, GREEN AR, RAKHA EA, BRENTNALL AR, ELLIS IO, KERMORGANT S and JONES JL, 2014. C-Met in invasive breast cancer: is there a relationship with the basal-like subtype? Cancer. 120(2), 163-71
• ULLENHAG GJ, AL-ATTAR A, MUKHERJEE A, GREEN AR, ELLIS IO and DURRANT LG, 2014. The TRAIL system is over-expressed in breast cancer and FLIP a marker of good prognosis. Journal of cancer research and clinical oncology. 141(3), 505-14
• ABDEL-FATAH TM, BALL G, LEE AH, PINDER S, MACMILAN RD, CORNFORD E, MOSELEY PM, SILVERMAN R, PRICE J, LATHAM B, PALMER D, CHAN A, ELLIS IO and CHAN SY, 2014. Nottingham Clinico-Pathological Response Index (NPRI) after neoadjuvant chemotherapy (Neo-ACT) accurately predicts clinical outcome in locally advanced breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 21(5), 1052-62
• FILIPOVIĆ A, LOMBARDO Y, FARONATO M, ABRAHAMS J, ABOAGYE E, NGUYEN QD, D'AQUA BB, RIDLEY A, GREEN A, RAHKA E, ELLIS I, RECCHI C, PRZULJ N, SARAJLIĆ A, ALATTIA JR, FRAERING P, DEONARAIN M and COOMBES RC, 2014. Anti-nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells. Breast cancer research and treatment. 148(2), 455-62
• VOLLAN HK, RUEDA OM, CHIN SF, CURTIS C, TURASHVILI G, SHAH S, LINGJÆRDE OC, YUAN Y, NG CK, DUNNING MJ, DICKS E, PROVENZANO E, SAMMUT S, MCKINNEY S, ELLIS IO, PINDER S, PURUSHOTHAM A, MURPHY LC, KRISTENSEN VN, , BRENTON JD, PHAROAH PD, BØRRESEN-DALE AL, APARICIO S and CALDAS C, 2014. A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer. Molecular oncology. 9(1), 115-27
• RUDRARAJU B, DROOG M, ABDEL-FATAH TM, ZWART W, GIANNOUDIS A, MALKI MI, MOORE D, PATEL H, SHAW J, ELLIS IO, CHAN S, BROOKE GN, NEVEDOMSKAYA E, LO NIGRO C, CARROLL J, COOMBES RC, BEVAN C, ALI S and PALMIERI C, 2014. Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer. Breast cancer research and treatment. 147(2), 295-309
• MOORE KM, THOMAS GJ, DUFFY SW, WARWICK J, GABE R, CHOU P, ELLIS IO, GREEN AR, HAIDER S, BROUILETTE K, SAHA A, VALLATH S, BOWEN R, CHELALA C, ECCLES D, TAPPER WJ, THOMPSON AM, QUINLAN P, JORDAN L, GILLETT C, BRENTNALL A, VIOLETTE S, WEINREB PH, KENDREW J, BARRY ST, HART IR, JONES JL and MARSHALL JF, 2014. Therapeutic targeting of integrin αvβ6 in breast cancer. Journal of the National Cancer Institute. 106(8),
• XU Y, ZHANG H, LIT LC, GROTHEY A, ATHANASIADOU M, KIRITSI M, LOMBARDO Y, FRAMPTON AE, GREEN AR, ELLIS IO, ALI S, LENZ HJ, THANOU M, STEBBING J and GIAMAS G, 2014. The kinase LMTK3 promotes invasion in breast cancer through GRB2-mediated induction of integrin β₁. Science signaling. 7(330), ra58
• GROOT KORMELINK T, POWE DG, KUIJPERS SA, ABUDUKELIMU A, FENS MH, PIETERS EH, KASSING VAN DER VEN WW, HABASHY HO, ELLIS IO, BLOKHUIS BR, THIO M, HENNINK WE, STORM G, REDEGELD FA and SCHIFFELERS RM, 2014. Immunoglobulin free light chains are biomarkers of poor prognosis in basal-like breast cancer and are potential targets in tumor-associated inflammation. Oncotarget. 5(10), 3159-67
• STEBBING J, ZHANG H, XU Y, LIT LC, GREEN AR, GROTHEY A, LOMBARDO Y, PERIYASAMY M, BLIGHE K, ZHANG W, SHAW JA, ELLIS IO, LENZ HJ and GIAMAS G, 2014. KSR1 regulates BRCA1 degradation and inhibits breast cancer growth. Oncogene. 34(16), 2103-14
• ABDEL-FATAH TM, MCARDLE SE, JOHNSON C, MOSELEY PM, BALL GR, POCKLEY AG, ELLIS IO, REES RC and CHAN SY, 2014. HAGE (DDX43) is a biomarker for poor prognosis and a predictor of chemotherapy response in breast cancer. British journal of cancer. 110(10), 2450-61
• LEE AH, KEY HP, BELL JA, KUMAH P, HODI Z and ELLIS IO, 2014. The effect of delay in fixation on HER2 expression in invasive carcinoma of the breast assessed with immunohistochemistry and in situ hybridisation. Journal of clinical pathology. 67(7), 573-5
• RAKHA EA, SORIA D, GREEN AR, LEMETRE C, POWE DG, NOLAN CC, GARIBALDI JM, BALL G and ELLIS IO, 2014. Nottingham Prognostic Index Plus (NPI+): a modern clinical decision making tool in breast cancer. British journal of cancer. 110(7), 1688-97
• POWE DG, DHONDALAY GK, LEMETRE C, ALLEN T, HABASHY HO, ELLIS IO, REES R and BALL GR, 2014. DACH1: its role as a classifier of long term good prognosis in luminal breast cancer. PloS one. 9(1), e84428
• YOUSSEF MM, PAISH EC, MURRAY JC, FARAG NM, SALEH K and ELLIS IO, 2014. Apoptosis of T-cell subsets in colorectal cancer in vivo. The Egyptian journal of immunology. 21(2), 61-74
• TAN PH, SCHNITT SJ, VAN DE VIJVER MJ, ELLIS IO and LAKHANI SR, 2014. Papillary and neuroendocrine breast lesions: the WHO stance. Histopathology. 66(6), 761-70
• SULTANA, R., ABDEL-FATAH, T., ABBOTTS, R., HAWKES, C., ALBARAKATI, N., SEEDHOUSE, C., BALL, G., CHAN, S., RAKHA, E.A., ELLIS, I.O. and MADHUSUDAN, S., 2013. Targeting XRCC1 deficiency in breast cancer for personalized therapy Cancer Research. 73(5), 1621-1634
• LAVERSIN SA, PHATAK VM, POWE DG, LI G, MILES AK, HUGHES DC, BALL GR, ELLIS IO, GRITZAPIS AD, MISSITZIS I, MCARDLE SEB and REES RC, 2013. Identification of novel breast cancer-associated transcripts by UniGene database mining and gene expression analysis in normal and malignant cells. Genes, chromosomes & cancer. 52(3), 316-29
• KHOSHNAW SM, RAKHA EA, ABDEL-FATAH T, NOLAN CC, HODI Z, MACMILLAN RD, ELLIS IO and GREEN AR, 2013. The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients. Breast cancer research and treatment. 137(1), 139-53
• BAKER BG, BALL GR, RAKHA EA, NOLAN CC, CALDAS C, ELLIS IO and GREEN AR, 2013. Lack of expression of the proteins GMPR2 and PPARα are associated with the basal phenotype and patient outcome in breast cancer. Breast cancer research and treatment. 137(1), 127-37
• RAKHA EA, TAN PH, SHAABAN A, TSE GM, ESTELLER FC, VAN DEURZEN CHM, PURNELL D, STOTTER A, CHAN T, YAMAGUCHI R, DODWELL D, JAGER A, SOLER MT, JUNEINAH E, PLAZA ML, HODI Z, MCCULLOCH T, LEE AHS and ELLIS IO, 2013. Do primary mammary osteosarcoma and chondrosarcoma exist? A review of a large multi-institutional series of malignant matrix-producing breast tumours. Breast (Edinburgh, Scotland). 22(1), 13-8
• RAKHA EA, SHAABAN AM, HAIDER SA, JENKINS J, MENON S, JOHNSON C, YAMAGUCHI R, MURPHY A, LISTON J, CORNFORD E, HAMILTON L, JAMES J, ELLIS IO and LEE AHS, 2013. Outcome of pure mucocele-like lesions diagnosed on breast core biopsy. Histopathology. (In Press.)
• MIRZA S, RAKHA EA, ALSHAREEDA A, MOHIBI S, ZHAO X, KATAFIASZ BJ, WANG J, GURUMURTHY CB, BELE A, ELLIS IO, GREEN AR, BAND H and BAND V, 2013. Cytoplasmic localization of alteration/deficiency in activation 3 (ADA3) predicts poor clinical outcome in breast cancer patients. Breast cancer research and treatment. 137(3), 721-31
• GILL MS, PAISH EC, RONAN J, GREEN AR, ELLIS IO and LEE AHS, 2013. Comparison of the PharmDx immunohistochemical system with standard methods for assessing estrogen and progesterone receptors in invasive carcinoma of the breast. Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry. 21(1), 90-3
• SYED, B.M., JOHNSTON, S.J., WONG, D.W.M., GREEN, A.R., WINTERBOTTOM, L., KENNEDY, H., SIMPSON, N., MORGAN, D.A.L., ELLIS, I.O. and CHEUNG, K.L., 2012. Long-term (37 years) clinical outcome of older women with early operable primary breast cancer managed in a dedicated clinic Annals of Oncology. 23(6), 1465-1471
• ALESKANDARANY MA, GREEN AR, BENHASOUNA AA, BARROS FF, NEAL KR, REIS-FILHO JS, ELLIS IO and RAKHA EA, 2012. Prognostic Value Of Proliferation Assay In The Luminal, Her2 Positive And Triple Negative Biological Classes Of Breast Cancer. Breast Cancer Research : Bcr. 14(1), R3 (In Press.)
• ROSS-INNES, C.S., STARK, R., TESCHENDORFF, A.E., HOLMES, K.A., ALI, H.R., DUNNING, M.J., BROWN, G.D., GOJIS, O., ELLIS, I.O., GREEN, A.R., ALI, S., CHIN, S., PALMIERI, C., CALDAS, C. and CARROLL, J.S., 2012. Differential oestrogen receptor binding is associated with clinical outcome in breast cancer Nature. 481(7381), 389-393
• GARIBALDI JM, ZHOU S, WANG X, JOHN RI and ELLIS IO, 2012. Incorporation Of Expert Variability Into Breast Cancer Treatment Recommendation In Designing Clinical Protocol Guided Fuzzy Rule System Models. Journal Of Biomedical Informatics. (In Press.)
• RAKHA, E.A., MARTIN, S., LEE, A.H.S., MORGAN, D., PHAROAH, P.D.P., HODI, Z., MACMILLAN, D. and ELLIS, I.O., 2012. The prognostic significance of lymphovascular invasion in invasive breast carcinoma Cancer. 118(15), 3670-3680
• LEE AHS, KEY HP, BELL JA, HODI Z and ELLIS IO, 2012. Concordance Of Her2 Status Assessed On Needle Core Biopsy And Surgical Specimens Of Invasive Carcinoma Of The Breast. Histopathology. (In Press.)
• JOHNSTON, S.J., KENNY, F.S., SYED, B.M., ROBERTSON, J.F.R., PINDER, S.E., WINTERBOTTOM, L., ELLIS, I.O., BLAMEY, R.W. and CHEUNG, K.L., 2012. A randomised trial of primary tamoxifen versus mastectomy plus adjuvant tamoxifen in fit elderly women with invasive breast carcinoma of high oestrogen receptor content: long-term results at 20 years of follow-up Annals of Oncology: Official Journal of the European Society for Medical Oncology. 23(9), 2296-2300
• ZHAO, X., MIRZA, S., ALSHAREEDA, A., ZHANG, Y., GURUMURTHY, C. B., BELE, A., KIM, J. H., MOHIBI, S., GOSWAMI, M., LELE, S. M., WEST, W., QIU, F., ELLIS, I. O., RAKHA, E. A., GREEN, A. R., BAND, H. and BAND, V., 2012. Overexpression of a novel cell cycle regulator ecdysoneless in breast cancer: a marker of poor prognosis in HER2/neu-overexpressing breast cancer patients: Breast Cancer Res Treat Breast Cancer Res Treat.
• NATRAJAN, R., MACKAY, A., LAMBROS, M. B., WEIGELT, B., WILKERSON, P. M., MANIE, E., GRIGORIADIS, A., A'HERN, R., VAN DER GROEP, P., KOZAREWA, I., POPOVA, T., MARIANI, O., TURALJIC, S., FURNEY, S. J., MARAIS, R., RODRUIGUES, D. N., FLORA, A. C., WAI, P., PAWAR, V., MCDADE, S., CARROLL, J., STOPPA-LYONNET, D., GREEN, A. R., ELLIS, I. O., SWANTON, C., VAN DIEST, P., DELATTRE, O., LORD, C. J., FOULKES, W. D., VINCENT-SALOMON, A., ASHWORTH, A., HENRI STERN, M. and REIS-FILHO, J. S., 2012. A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers: J Pathol J Pathol.
• MAHMOUD, S. M., LEE, A. H., PAISH, E. C., MACMILLAN, R. D., ELLIS, I. O. and GREEN, A. R., 2012. Tumour-infiltrating macrophages and clinical outcome in breast cancer: J Clin Pathol J Clin Pathol. 65(2), 159-63
• LEE, A. H., RAKHA, E. A., HODI, Z. and ELLIS, I. O., 2012. Re-audit of revised method for assessing the mitotic component of histological grade in needle core biopsies of invasive carcinoma of the breast: Histopathology Histopathology.
• CURTIS, C., SHAH, S.P., CHIN, S., TURASHVILI, G., RUEDA, O.M., DUNNING, M.J., SPEED, D., LYNCH, A.G., SAMARAJIWA, S., YUAN, Y., GRAF, S., HA, G., HAFFARI, G., BASHASHATI, A., RUSSELL, R., MCKINNEY, S., METABRIC GROUP, LANGEROD, A., GREEN, A., PROVENZANO, E., WISHART, G., PINDER, S., WATSON, P., MARKOWETZ, F., MURPHY, L., ELLIS, I., PURUSHOTHAM, A., BORRESEN-DAL, A., BRENTON, J.D., TAVARE, S., CALDAS, C. and APARACIO, S., 2012. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups Nature. 486(7403), 346-352
• WOOLSTON CM, ZHANG L, STORR SJ, AL-ATTAR A, SHEHATA M, ELLIS IO, CHAN SY and MARTIN SG, 2012. The prognostic and predictive power of redox protein expression for anthracycline-based chemotherapy response in locally advanced breast cancer. Modern pathology : an official journal of the united states and canadian academy of pathology, inc. 25(8), 1106-16
• STORR, S.J., LEE, K.W., WOOLSTON, C.M., SAFUAN, S., GREEN, A.R., MACMILLAN, R.D., BENHASOUNA, A., PARR, T., ELLIS, I.O. and MARTIN, S.G., 2012. Calpain system protein expression in basal-like and triple-negative invasive breast cancer Annals of Oncology: Official Journal of the European Society for Medical Oncology. 23(9), 2289-2296
• ALESKANDARANY, M. A., NEGM, O. H., RAKHA, E. A., AHMED, M. A., NOLAN, C. C., BALL, G. R., CALDAS, C., GREEN, A. R., TIGHE, P. J. and ELLIS, I. O., 2012. TOMM34 expression in early invasive breast cancer: a biomarker associated with poor outcome Breast cancer research and treatment. 136(2), 419-27
• RAKHA EA, TEOH TK, LEE AHS, NOLAN CC, ELLIS IO and GREEN AR, 2012. Further evidence that E-cadherin is not a tumour suppressor gene in invasive ductal carcinoma of the breast: an immunohistochemical study. Histopathology. (In Press.)
• RAKHA EA, VAN DEURZEN CHM, PAISH EC, MACMILLAN RD, ELLIS IO and LEE AHS, 2012. Pleomorphic lobular carcinoma of the breast: is it a prognostically significant pathological subtype independent of histological grade? Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. (In Press.)
• LEE AHS, VILLENA SALINAS NM, HODI Z, RAKHA EA and ELLIS IO, 2012. The value of examination of multiple levels of mammary needle core biopsy specimens taken for investigation of lesions other than calcification. Journal of clinical pathology. 65(12), 1097-9
• AGBOOLA AJ, MUSA AA, WANANGWA N, ABDEL-FATAH T, NOLAN CC, AYOADE BA, OYEBADEJO TY, BANJO AA, DEJI-AGBOOLA AM, RAKHA EA, GREEN AR and ELLIS IO, 2012. Molecular characteristics and prognostic features of breast cancer in Nigerian compared with UK women. Breast cancer research and treatment. 135(2), 555-69
• KHOSHNAW SM, RAKHA EA, ABDEL-FATAH TM, NOLAN CC, HODI Z, MACMILLAN DR, ELLIS IO and GREEN AR, 2012. Loss of Dicer expression is associated with breast cancer progression and recurrence. Breast cancer research and treatment. 135(2), 403-13
• WALKER RA, HANBY A, PINDER SE, THOMAS J, ELLIS IO and NATIONAL COORDINATING COMMITTEE FOR BREAST PATHOLOGY RESEARCH SUBGROUP, 2012. Current issues in diagnostic breast pathology. Journal of clinical pathology. 65(9), 771-85
• RAKHA EA, LEE AHS, ROBERTS J, VILLENA SALINAS NM, HODI Z, ELLIS IO and REIS-FILHO JS, 2012. Low-estrogen receptor-positive breast cancer: the impact of tissue sampling, choice of antibody, and molecular subtyping. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 30(23), 2929-30; author reply 2931
• ALSHAREEDA AT, RAKHA EA, NOLAN CC, ELLIS IO and GREEN AR, 2012. Fatty acid binding protein 7 expression and its sub-cellular localization in breast cancer. Breast cancer research and treatment. 134(2), 519-29
• RAKHA EA, TUN M, JUNAINAH E, ELLIS IO and GREEN A, 2012. Encapsulated papillary carcinoma of the breast: a study of invasion associated markers. Journal of clinical pathology. 65(8), 710-4
• YAMAGUCHI R, MAESHIRO K, ELLIS IO, RAKHA EA, TAGUCHI J, SHIMA I, KAMEI H, SUZUKI M, IMAMURA M, NAKAYAMA G and YANO H, 2012. Infiltrative epitheliosis of the breast. Journal of clinical pathology. 65(8), 766-8
• SHAW EC, HANBY AM, WHEELER K, SHAABAN AM, POLLER D, BARTON S, TREANOR D, FULFORD L, WALKER RA, RYAN D, LAKHANI SR, WELLS CA, ROCHE H, THEAKER JM, ELLIS IO, JONES JL and ECCLES DM, 2012. Observer agreement comparing the use of virtual slides with glass slides in the pathology review component of the POSH breast cancer cohort study. Journal of clinical pathology. 65(5), 403-8
• MOHAMMED, R.A.A., MARTIN, S.G., MAHMMOD, A.M., MACMILLAN, R.D., GREEN, A.R., PAISH, E.C. and ELLIS, I.O., 2011. Objective assessment of lymphatic and blood vascular invasion in lymph node-negative breast carcinoma: findings from a large case series with long-term follow-up The Journal of pathology: a journal of the Pathological Society of Great Britain and Ireland. 223(3), 358-365
• WOOLSTON CM, STORR SJ, ELLIS IO, MORGAN DAL and MARTIN SG., 2011. Expression of thioredoxin system and related peroxiredoxin proteins is associated with clinical outcome in radiotherapy treated early stage breast cancer. Radiotherapy and Oncology. 100(2), 308-313
• FILIPOVIĆ, ALEKSANDRA, GRONAU, JULIAN HENDRIK, GREEN, ANDREW R, WANG, JAYSON, VALLATH, SABARI, SHAO, DONGMIN, RASUL, SABEENA, ELLIS, IAN O, YAGÜE, ERNESTO, STURGE, JUSTIN and COOMBES, R CHARLES, 2011. Biological and clinical implications of nicastrin expression in invasive breast cancer. Breast cancer research and treatment. 125(1), 43-53
• SYED, B.M., AL-KHYATT, W., JOHNSTON, S.J., WONG, D.W.M., WINTERBOTTOM, L., KENNEDY, H., GREEN, A.R., MORGAN, D.A.L., ELLIS, I.O. and CHEUNG, K.L., 2011. Long-term clinical outcome of oestrogen receptor-positive operable primary breast cancer in older women: a large series from a single centre British Journal of Cancer. 104(9), 1393-1400
• AHMED MAH, ALESKANDARANY MA, RAKHA EA, MOUSTAFA RZA, BENHASOUNA A, NOLAN C, GREEN AR, ILYAS M and ELLIS IO, 2011. A Cd44(-)/Cd24 (+) Phenotype Is A Poor Prognostic Marker In Early Invasive Breast Cancer. Breast Cancer Research And Treatment. (In Press.)
• AGBOOLA AJ, PAISH EC, RAKHA EA, POWE DG, MACMILLAN RD, ELLIS IO and GREEN AR, 2011. Epcam Expression Is An Indicator Of Recurrence In Basal-Like Breast Cancer. Breast Cancer Research And Treatment. (In Press.)
• CUZICK, J., DOWSETT, M., PINEDA, S., WALE, C., SALTER, J., QUINN, E., ZABAGLO, L., MALLON, E., GREEN, A.R., ELLIS, I.O., HOWELL, A., BUZDAR, A.U. and FORBES, J.F., 2011. Prognostic value of a combined estrogen receptor, progesterone receptor, Ki-67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the genomic health recurrence score in early breast cancer Journal Of Clinical Oncology. 29(32), 4273-4278
• GIAMAS, G., FILIPOVIĆ, A., JACOB, J., MESSIER, W., ZHANG, H., YANG, D., ZHANG, W., SHIFA, B.A., PHOTIOU, A., TRALAU-STEWART, C., CASTELLANO, L., GREEN, A.R., COOMBES, R.C., ELLIS, I.O., ALI, S., LENZ, H.J. and STEBBING, J., 2011. Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer Nature Medicine. 17(6), 715-719
• BERAL V, ALEXANDER M, DUFFY S, ELLIS IO, GIVEN-WILSON R, HOLMBERG L, MOSS SM, RAMIREZ A, REED MWR, RUBIN C, WHELEHAN P, WILSON R and YOUNG KC, 2011. The Number Of Women Who Would Need To Be Screened Regularly By Mammography To Prevent One Death From Breast Cancer. Journal Of Medical Screening. 18(4), 210-2
• MAHMOUD, S.M.A., PAISH, E.C., POWE, D.G., MACMILLAN, R.D., GRAINGE, M.J., LEE, A.H.S., ELLIS, I.O. and GREEN, A.R., 2011. Tumor-infiltrating CD8⁺ lymphocytes predict clinical outcome in breast cancer Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology. 29(15), 1949-1955
• LEE AHS, KEY HP, BELL JA, HODI Z and ELLIS IO, 2011. Breast Carcinomas With Borderline (2+) Her2 Immunohistochemistry: Percentage Of Cells With Complete Membrane Staining For Her2 And The Frequency Of Her2 Amplification. Journal Of Clinical Pathology. 64(6), 490-2
• RAKHA EA, HO BC, NAIK V, SEN S, HAMILTON LJ, HODI Z, ELLIS IO and LEE AHS, 2011. Outcome Of Breast Lesions Diagnosed As Lesion Of Uncertain Malignant Potential (B3) Or Suspicious Of Malignancy (B4) On Needle Core Biopsy, Including Detailed Review Of Epithelial Atypia. Histopathology. 58(4), 626-32
• HOLLAND DG, BURLEIGH A, GIT A, GOLDGRABEN MA, PEREZ-MANCERA PA, CHIN S, HURTADO A, BRUNA A, ALI HR, GREENWOOD W, DUNNING MJ, SAMARAJIWA S, MENON S, RUEDA OM, LYNCH AG, MCKINNEY S, ELLIS IO, EAVES CJ, CARROLL JS, CURTIS C, APARICIO S and CALDAS C, 2011. Znf703 Is A Common Luminal B Breast Cancer Oncogene That Differentially Regulates Luminal And Basal Progenitors In Human Mammary Epithelium. Embo Molecular Medicine. 3(3), 167-80
• ALI AMG, DAWSON S, BLOWS FM, PROVENZANO E, ELLIS IO, BAGLIETTO L, HUNTSMAN D, CALDAS C and PHAROAH PD, 2011. Comparison Of Methods For Handling Missing Data On Immunohistochemical Markers In Survival Analysis Of Breast Cancer. British Journal Of Cancer. 104(4), 693-9
• CUZICK, J., SESTAK, I., PINDER, S.E., ELLIS, I.O., FORSYTH, S., BUNDRED, N.J., FORBES, J.F., BISHOP, H., FENTIMAN, I.S. and GEORGE, W.D., 2011. Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK/ANZ DCIS trial Lancet Oncology. 12(1), 21-29
• WOOLSTON, C. M., AL-ATTAR, A., STORR, S. J., ELLIS, I. O., MORGAN, D. A. and MARTIN, S. G., 2011. Redox protein expression predicts radiotherapeutic response in early-stage invasive breast cancer patients: Int J Radiat Oncol Biol Phys Int J Radiat Oncol Biol Phys. 79(5), 1532-40
• VAN DEURZEN, C. H., LEE, A. H., GILL, M. S., MENKE-PLUIJMERS, M. B., JAGER, A., ELLIS, I. O. and RAKHA, E. A., 2011. Metaplastic breast carcinoma: tumour histogenesis or dedifferentiation?: J Pathol J Pathol. 224(4), 434-7
• TANG, S. W., PARKER, H., WINTERBOTTOM, L., HASSELL, K., ELLIS, I. O., MORGAN, D. A. and CHEUNG, K. L., 2011. Early primary breast cancer in the elderly - pattern of presentation and treatment: Surg Oncol Surg Oncol. 20(1), 7-12
• STORR, S. J., WOOLSTON, C. M., BARROS, F. F., GREEN, A. R., SHEHATA, M., CHAN, S. Y., ELLIS, I. O. and MARTIN, S. G., 2011. Calpain-1 expression is associated with relapse-free survival in breast cancer patients treated with trastuzumab following adjuvant chemotherapy: Int J Cancer Int J Cancer. 129(7), 1773-80
• STORR, S. J., SAFUAN, S., MITRA, A., ELLIOTT, F., WALKER, C., VASKO, M. J., HO, B., COOK, M., MOHAMMED, R. A., PATEL, P. M., ELLIS, I. O., NEWTON-BISHOP, J. A. and MARTIN, S. G., 2011. Objective assessment of blood and lymphatic vessel invasion and association with macrophage infiltration in cutaneous melanoma: Mod Pathol Mod Pathol.
• STORR, S. J., MOHAMMED, R.A.A., WOOLSTON, C.M., GREEN, A.R., PARR, T., SPITERI, I., CALDAS, C., BALL, G.R., ELLIS, I.O. and MARTIN, S.G., 2011. Calpastatin is associated with lymphovascular invasion in breast cancer The Breast. 20(5), 413-418
• STEBBING, J., FILIPOVIC, A., ELLIS, I. O., GREEN, A. R., D'SILVA, T. R., LENZ, H. J., COOMBES, R. C., WANG, T., LEE, S. C. and GIAMAS, G., 2011. LMTK3 expression in breast cancer: association with tumor phenotype and clinical outcome: Breast Cancer Res Treat Breast Cancer Res Treat.
• RICHARDSON, J., SHAABAN, A. M., KAMAL, M., ALISARY, R., WALKER, C., ELLIS, I. O., SPEIRS, V., GREEN, A. R. and BELL, S. M., 2011. Microcephalin is a new novel prognostic indicator in breast cancer associated with BRCA1 inactivation: Breast Cancer Res Treat Breast Cancer Res Treat. 127(3), 639-48
• RAKHA, E. A., LEE, A. H., JENKINS, J. A., MURPHY, A. E., HAMILTON, L. J. and ELLIS, I. O., 2011. Characterization and outcome of breast needle core biopsy diagnoses of lesions of uncertain malignant potential (B3) in abnormalities detected by mammographic screening: Int J Cancer Int J Cancer. 129(6), 1417-24
• RAKHA, E. A., HO, B. C., NAIK, V., SEN, S., HAMILTON, L. J., HODI, Z., ELLIS, I. O. and LEE, A. H., 2011. Outcome of breast lesions diagnosed as lesion of uncertain malignant potential (B3) or suspicious of malignancy (B4) on needle core biopsy, including detailed review of epithelial atypia: Histopathology Histopathology. 58(4), 626-32
• RAKHA, E. A., GANDHI, N., CLIMENT, F., VAN DEURZEN, C. H., HAIDER, S. A., DUNK, L., LEE, A. H., MACMILLAN, D. and ELLIS, I. O., 2011. Encapsulated papillary carcinoma of the breast: an invasive tumor with excellent prognosis: Am J Surg Pathol Am J Surg Pathol. 35(8), 1093-103
• RAKHA, E. A. and ELLIS, I. O., 2011. Modern classification of breast cancer: should we stick with morphology or convert to molecular profile characteristics: Adv Anat Pathol Adv Anat Pathol. 18(4), 255-67
• POWE, D. G., VOSS, M. J., HABASHY, H. O., ZANKER, K. S., GREEN, A. R., ELLIS, I. O. and ENTSCHLADEN, F., 2011. Alpha- and beta-adrenergic receptor (AR) protein expression is associated with poor clinical outcome in breast cancer: an immunohistochemical study: Breast Cancer Res Treat Breast Cancer Res Treat. 130(2), 457-63
• O'SHEA, A. M., RAKHA, E. A., HODI, Z., ELLIS, I. O. and LEE, A. H., 2011. Histological grade of invasive carcinoma of the breast assessed on needle core biopsy - modifications to mitotic count assessment to improve agreement with surgical specimens: Histopathology Histopathology. 59(3), 543-8
• MVERE, M. Z., JAMES, J. J., CORNFORD, E. J., TENNANT, S. L., EVANS, A. J., ELLIS, I. O. and CHAN, S. Y., 2011. Frequency and patterns of metastatic disease in locally advanced inflammatory and non-inflammatory breast cancer: Clin Oncol (R Coll Radiol) Clin Oncol (R Coll Radiol). 23(9), 608-12
• MOHAMMED, R. A., ELLIS, I. O., MAHMMOD, A. M., HAWKES, E. C., GREEN, A. R., RAKHA, E. A. and MARTIN, S. G., 2011. Lymphatic and blood vessels in basal and triple-negative breast cancers: characteristics and prognostic significance: Mod Pathol Mod Pathol. 24(6), 774-85
• MAHMOUD, S. M., PAISH, E. C., POWE, D. G., MACMILLAN, R. D., LEE, A. H., ELLIS, I. O. and GREEN, A. R., 2011. An evaluation of the clinical significance of FOXP3+ infiltrating cells in human breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat. 127(1), 99-108
• MAHMOUD, S. M., LEE, A. H., PAISH, E. C., MACMILLAN, R. D., ELLIS, I. O. and GREEN, A. R., 2011. The prognostic significance of B lymphocytes in invasive carcinoma of the breast: Breast Cancer Res Treat Breast Cancer Res Treat.
• LEE, A. H., KEY, H. P., BELL, J. A., HODI, Z. and ELLIS, I. O., 2011. Breast carcinomas with borderline (2+) HER2 immunohistochemistry: percentage of cells with complete membrane staining for HER2 and the frequency of HER2 amplification: J Clin Pathol J Clin Pathol. 64(6), 490-2
• KNOWLDEN, J. M., GEE, J. M., BARROW, D., ROBERTSON, J. F., ELLIS, I. O., NICHOLSON, R. I. and HUTCHESON, I. R., 2011. erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines: Breast Cancer Res Breast Cancer Res. 13(5), R93
• KHOSHNAW, S. M., POWE, D. G., ELLIS, I. O. and GREEN, A. R., 2011. Detection and quantification of microRNAs in laser-microdissected formalin-fixed paraffin-embedded breast cancer tissues: Methods Mol Biol Methods Mol Biol. 755, 119-42
• HOLLAND, D. G., BURLEIGH, A., GIT, A., GOLDGRABEN, M. A., PEREZ-MANCERA, P. A., CHIN, S. F., HURTADO, A., BRUNA, A., ALI, H. R., GREENWOOD, W., DUNNING, M. J., SAMARAJIWA, S., MENON, S., RUEDA, O. M., LYNCH, A. G., MCKINNEY, S., ELLIS, I. O., EAVES, C. J., CARROLL, J. S., CURTIS, C., APARICIO, S. and CALDAS, C., 2011. ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium: EMBO Mol Med EMBO Mol Med. 3(3), 167-80
• HABASHY, H. O., RAKHA, E. A., ALESKANDARANY, M., AHMED, M. A., GREEN, A. R., ELLIS, I. O. and POWE, D. G., 2011. FOXO3a nuclear localisation is associated with good prognosis in luminal-like breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat. 129(1), 11-21
• HABASHY, H. O., POWE, D. G., GLAAB, E., BALL, G., SPITERI, I., KRASNOGOR, N., GARIBALDI, J. M., RAKHA, E. A., GREEN, A. R., CALDAS, C. and ELLIS, I. O., 2011. RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: a marker of ER-positive luminal-like subtype: Breast Cancer Res Treat Breast Cancer Res Treat. 128(2), 315-26
• HABASHY, H. O., POWE, D. G., ABDEL-FATAH, T. M., GEE, J. M., NICHOLSON, R. I., GREEN, A. R., RAKHA, E. A. and ELLIS, I. O., 2011. A review of the biological and clinical characteristics of luminal-like oestrogen receptor-positive breast cancer: Histopathology Histopathology.
• FILIPOVIC, A., GRONAU, J. H., GREEN, A. R., WANG, J., VALLATH, S., SHAO, D., RASUL, S., ELLIS, I. O., YAGUE, E., STURGE, J. and COOMBES, R. C., 2011. Biological and clinical implications of nicastrin expression in invasive breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat. 125(1), 43-53
• FERNANDEZ, B., PAISH, E. C., GREEN, A. R., LEE, A. H., MACMILLAN, R. D., ELLIS, I. O. and RAKHA, E. A., 2011. Lymph-node metastases in invasive lobular carcinoma are different from those in ductal carcinoma of the breast: J Clin Pathol J Clin Pathol. 64(11), 995-1000
• CHEUNG, K. L., ELLIS, I. O., MORGAN, D. A., LEONARD, R., REED, M. W., POROCK, D., WINTERBOTTOM, L. and BARNARD, K., 2011. Optimising the management of primary breast cancer in older women - a report of a multi-disciplinary study day: Breast Breast. 20(6), 581-4
• BIGANZOLI, E., CORADINI, D., AMBROGI, F., GARIBALDI, J. M., LISBOA, P., SORIA, D., GREEN, A. R., PEDRIALI, M., PIANTELLI, M., QUERZOLI, P., DEMICHELI, R., BORACCHI, P., NENCI, I., ELLIS, I. O. and ALBERTI, S., 2011. p53 status identifies two subgroups of triple-negative breast cancers with distinct biological features: Jpn J Clin Oncol Jpn J Clin Oncol. 41(2), 172-9
• BERAL, V., ALEXANDER, M., DUFFY, S., ELLIS, I. O., GIVEN-WILSON, R., HOLMBERG, L., MOSS, S. M., RAMIREZ, A., REED, M. W., RUBIN, C., WHELEHAN, P., WILSON, R. and YOUNG, K. C., 2011. The number of women who would need to be screened regularly by mammography to prevent one death from breast cancer: J Med Screen J Med Screen. 18(4), 210-2
• BENNETT, R. L., EVANS, A. J., KUTT, E., RECORD, C., BOBROW, L. G., ELLIS, I. O., HANBY, A. and MOSS, S. M., 2011. Pathological and mammographic prognostic factors for screen detected cancers in a multi-centre randomised, controlled trial of mammographic screening in women from age 40 to 48 years: Breast Breast. 20(6), 525-8
• BARTLETT, J. M., STARCZYNSKI, J., ATKEY, N., KAY, E., O'GRADY, A., GANDY, M., IBRAHIM, M., JASANI, B., ELLIS, I. O., PINDER, S. E. and WALKER, R. A., 2011. HER2 testing in the UK: recommendations for breast and gastric in-situ hybridisation methods: J Clin Pathol J Clin Pathol. 64(8), 649-53
• BADVE, S., DABBS, D. J., SCHNITT, S. J., BAEHNER, F. L., DECKER, T., EUSEBI, V., FOX, S. B., ICHIHARA, S., JACQUEMIER, J., LAKHANI, S. R., PALACIOS, J., RAKHA, E. A., RICHARDSON, A. L., SCHMITT, F. C., TAN, P. H., TSE, G. M., WEIGELT, B., ELLIS, I. O. and REIS-FILHO, J. S., 2011. Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists: Mod Pathol Mod Pathol. 24(2), 157-67
• AMMAR, A., MOHAMMED, R. A., SALMI, M., PEPPER, M., PAISH, E. C., ELLIS, I. O. and MARTIN, S. G., 2011. Lymphatic expression of CLEVER-1 in breast cancer and its relationship with lymph node metastasis: Anal Cell Pathol (Amst) Anal Cell Pathol (Amst). 34(1-2), 67-78
• ALI, A. M., DAWSON, S. J., BLOWS, F. M., PROVENZANO, E., ELLIS, I. O., BAGLIETTO, L., HUNTSMAN, D., CALDAS, C. and PHAROAH, P. D., 2011. Comparison of methods for handling missing data on immunohistochemical markers in survival analysis of breast cancer: Br J Cancer Br J Cancer. 104(4), 693-9
• ALESKANDARANY, M. A., RAKHA, E. A., MACMILLAN, R. D., POWE, D. G., ELLIS, I. O. and GREEN, A. R., 2011. MIB1/Ki-67 labelling index can classify grade 2 breast cancer into two clinically distinct subgroups: Breast Cancer Res Treat Breast Cancer Res Treat. 127(3), 591-9
• ALESKANDARANY, M. A., RAKHA, E. A., AHMED, M. A., POWE, D. G., ELLIS, I. O. and GREEN, A. R., 2011. Clinicopathologic and molecular significance of phospho-Akt expression in early invasive breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat. 127(2), 407-16
• ALBASRI, A., ALESKANDARANY, M., BENHASOUNA, A., POWE, D. G., ELLIS, I. O., ILYAS, M. and GREEN, A. R., 2011. CTEN (C-terminal tensin-like), a novel oncogene overexpressed in invasive breast carcinoma of poor prognosis: Breast Cancer Res Treat Breast Cancer Res Treat. 126(1), 47-54
• AHMED, M. A., ALESKANDARANY, M. A., RAKHA, E. A., MOUSTAFA, R. Z., BENHASOUNA, A., NOLAN, C., GREEN, A. R., ILYAS, M. and ELLIS, I. O., 2011. A CD44(-)/CD24 (+) phenotype is a poor prognostic marker in early invasive breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat.
• AGBOOLA, A. J., PAISH, E. C., RAKHA, E. A., POWE, D. G., MACMILLAN, R. D., ELLIS, I. O. and GREEN, A. R., 2011. EpCAM expression is an indicator of recurrence in basal-like breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat.
• HABASHY, HANY ONSY, POWE, DESMOND G, RAKHA, EMAD A, BALL, GRAHAM, MACMILLAN, R DOUGLAS, GREEN, ANDREW R and ELLIS, IAN O, 2010. The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype. Breast cancer research and treatment. 120(3), 603-12
• HABASHY, HANY ONSY, POWE, DESMOND G, GLAAB, ENRICO, BALL, GRAHAM, SPITERI, INMACULADA, KRASNOGOR, NATALIO, GARIBALDI, JONATHAN M, RAKHA, EMAD A, GREEN, ANDREW R, CALDAS, C and ELLIS, IAN O, 2010. RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: a marker of ER-positive luminal-like subtype. Breast cancer research and treatment.
• HABASHY, HANY ONSY, POWE, DESMOND G, STAKA, CINDY M, RAKHA, EMAD A, BALL, GRAHAM, GREEN, ANDREW R, ALESKANDARANY, MOHAMMED, PAISH, E CLAIRE, DOUGLAS MACMILLAN, R, NICHOLSON, ROBERT I, ELLIS, IAN O and GE, 2010. Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen. Breast cancer research and treatment. 119(2), 283-93
• SORIA, D., GARIBALDI, J.M., AMBROGI, F., GREEN, A.R., POWE, D., RAKHA, E., MACMILLAN, R.D., BLAMEY, R.W., BALL, G., LISBOA, P.J.G., ETCHELLS, T.A., BORACCHI, P., BIGANZOLI, E. and ELLIS, I.O., 2010. A methodology to identify consensus classes from clustering algorithms applied to immunohistochemical data from breast cancer patients Computers in Biology and Medicine. 40(3), 318-330
• BLOWS, F.M., DRIVER, K.E., SCHMIDT, M.K., BROEKS, A., LEEUWEN, F.E. VAN, WESSELING, J., CHEANG, M.C., GELMON, K., NIELSEN, T.O., BLOMQVIST, C., HEIKKILÄ, P., HEIKKINEN, T., NEVANLINNA, H., AKSLEN, L.A., BÉGIN, L.R., FOULKES, W.D., COUCH, F.J., WANG, X., CAFOUREK, V., OLSON, J.E., BAGLIETTO, L., GILES, G.G., SEVERI, G., MCLEAN, C.A., SOUTHEY, M.C. and RAKHA, E., 2010. Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies PLoS Medicine. 7(5), e1000279
• ALESKANDARANY, MOHAMMED A, RAKHA, EMAD A, MACMILLAN, R DOUGLAS, POWE, DESMOND G, ELLIS, IAN O and GREEN, ANDREW R, 2010. MIB1/Ki-67 labelling index can classify grade 2 breast cancer into two clinically distinct subgroups. Breast cancer research and treatment.
• RAKHA, E.A., LEE, A.H.S., EVANS, A.J., MENON, S., ASSAD, N.Y., HODI, Z., MACMILLAN, D., BLAMEY, R.W. and ELLIS, I.O., 2010. Tubular carcinoma of the breast: further evidence to support its excellent prognosis Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology. 28(1), 99-104
• RAKHA, EMAD A, LEE, ANDREW HS, JENKINS, JACQUIE A, MURPHY, ALISON E, HAMILTON, LISA J and ELLIS, IAN O, 2010. Characterisation and outcome of breast needle core biopsy diagnoses of lesions of uncertain malignant potential (B3) in abnormalities detected by mammographic screening. International journal of cancer. Journal international du cancer.
• MAHMOUD, SAHAR M A, PAISH, EMMA C, POWE, DESMOND G, MACMILLAN, R DOUGLAS, LEE, ANDREW H S, ELLIS, IAN O and GREEN, ANDREW R, 2010. An evaluation of the clinical significance of FOXP3(+) infiltrating cells in human breast cancer. Breast cancer research and treatment.
• POWE DG, VOSS MJ, ZÄNKER KS, HABASHY HO, GREEN AR, ELLIS IO and ENTSCHLADEN F, 2010. Beta-Blocker Drug Therapy Reduces Secondary Cancer Formation In Breast Cancer And Improves Cancer Specific Survival. Oncotarget. 1(7), 628-38
• ZHANG, H., RAKHA, E. A., BALL, G. R., SPITERI, I., ALESKANDARANY, M., PAISH, E. C., POWE, D. G., MACMILLAN, R. D., CALDAS, C., ELLIS, I. O. and GREEN, A. R., 2010. The proteins FABP7 and OATP2 are associated with the basal phenotype and patient outcome in human breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat. 121(1), 41-51
• RAKHA, E. A., REIS-FILHO, J. S. and ELLIS, I. O., 2010. Combinatorial biomarker expression in breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat. 120(2), 293-308
• RAKHA, E. A., REIS-FILHO, J. S., BAEHNER, F., DABBS, D. J., DECKER, T., EUSEBI, V., FOX, S. B., ICHIHARA, S., JACQUEMIER, J., LAKHANI, S. R., PALACIOS, J., RICHARDSON, A. L., SCHNITT, S. J., SCHMITT, F. C., TAN, P. H., TSE, G. M., BADVE, S. and ELLIS, I. O., 2010. Breast cancer prognostic classification in the molecular era: the role of histological grade: Breast Cancer Res Breast Cancer Res. 12(4), 207
• RAKHA, E. A., PATEL, A., POWE, D. G., BENHASOUNA, A., GREEN, A. R., LAMBROS, M. B., REIS-FILHO, J. S. and ELLIS, I. O., 2010. Clinical and biological significance of E-cadherin protein expression in invasive lobular carcinoma of the breast: Am J Surg Pathol Am J Surg Pathol. 34(10), 1472-9
• RAKHA, E. A., LEE, A. H., REED, J., MURPHY, A., EL-SAYED, M., BURRELL, H., EVANS, A. J. and ELLIS, I. O., 2010. Screen-detected malignant breast lesions diagnosed following benign (B2) or normal (B1) needle core biopsy diagnoses: Eur J Cancer Eur J Cancer. 46(10), 1835-40
• RAKHA, E. A. and ELLIS, I. O., 2010. Lobular breast carcinoma and its variants: Semin Diagn Pathol Semin Diagn Pathol. 27(1), 49-61
• PROVENZANO, E., BARTER, S. J., WRIGHT, P. A., FOROUHI, P., ALLIBONE, R. and ELLIS, I. O., 2010. Erdheim-chester disease presenting as bilateral clinically malignant breast masses: Am J Surg Pathol Am J Surg Pathol. 34(4), 584-8
• POWE, D. G., VOSS, M. J., ZANKER, K. S., HABASHY, H. O., GREEN, A. R., ELLIS, I. O. and ENTSCHLADEN, F., 2010. Beta-blocker drug therapy reduces secondary cancer formation in breast cancer and improves cancer specific survival: Oncotarget Oncotarget. 1(7), 628-38
• PINDER, S. E., DUGGAN, C., ELLIS, I. O., CUZICK, J., FORBES, J. F., BISHOP, H., FENTIMAN, I. S. and GEORGE, W. D., 2010. A new pathological system for grading DCIS with improved prediction of local recurrence: results from the UKCCCR/ANZ DCIS trial: Br J Cancer Br J Cancer. 103(1), 94-100
• MARGINEAN, F., RAKHA, E. A., HO, B. C., ELLIS, I. O. and LEE, A. H., 2010. Histological features of medullary carcinoma and prognosis in triple-negative basal-like carcinomas of the breast: Mod Pathol Mod Pathol. 23(10), 1357-63
• LANCASHIRE, L. J., POWE, D. G., REIS-FILHO, J. S., RAKHA, E., LEMETRE, C., WEIGELT, B., ABDEL-FATAH, T. M., GREEN, A. R., MUKTA, R., BLAMEY, R., PAISH, E. C., REES, R. C., ELLIS, I. O. and BALL, G. R., 2010. A validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks: Breast Cancer Res Treat Breast Cancer Res Treat. 120(1), 83-93
• LACROIX-TRIKI, M., GEYER, F. C., LAMBROS, M. B., SAVAGE, K., ELLIS, I. O., LEE, A. H. and REIS-FILHO, J. S., 2010. beta-catenin/Wnt signalling pathway in fibromatosis, metaplastic carcinomas and phyllodes tumours of the breast: Mod Pathol Mod Pathol. 23(11), 1438-48
• KWOK, T. C., RAKHA, E. A., LEE, A. H., GRAINGE, M., GREEN, A. R., ELLIS, I. O. and POWE, D. G., 2010. Histological grading of breast cancer on needle core biopsy: the role of immunohistochemical assessment of proliferation: Histopathology Histopathology. 57(2), 212-9
• HODI, Z., ELLIS, I. O., ELSTON, C. W., PINDER, S. E., DONOVAN, G., MACMILLAN, R. D. and LEE, A. H., 2010. Comparison of margin assessment by radial and shave sections in wide local excision specimens for invasive carcinoma of the breast: Histopathology Histopathology. 56(5), 573-80
• HABASHY, H. O., POWE, D. G., STAKA, C. M., RAKHA, E. A., BALL, G., GREEN, A. R., ALESKANDARANY, M., PAISH, E. C., DOUGLAS MACMILLAN, R., NICHOLSON, R. I., ELLIS, I. O. and GEE, J. M., 2010. Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen: Breast Cancer Res Treat Breast Cancer Res Treat. 119(2), 283-93
• HABASHY, H. O., POWE, D. G., RAKHA, E. A., BALL, G., MACMILLAN, R. D., GREEN, A. R. and ELLIS, I. O., 2010. The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype: Breast Cancer Res Treat Breast Cancer Res Treat. 120(3), 603-12
• GARCIA-CABALLERO, T., GRABAU, D., GREEN, A. R., GREGORY, J., SCHAD, A., KOHLWES, E., ELLIS, I. O., WATTS, S. and MOLLERUP, J., 2010. Determination of HER2 amplification in primary breast cancer using dual-colour chromogenic in situ hybridization is comparable to fluorescence in situ hybridization: a European multicentre study involving 168 specimens: Histopathology Histopathology. 56(4), 472-80
• FRYE, M., DRAGONI, I., CHIN, S. F., SPITERI, I., KUROWSKI, A., PROVENZANO, E., GREEN, A., ELLIS, I. O., GRIMMER, D., TESCHENDORFF, A., ZOUBOULIS, C. C., CALDAS, C. and WATT, F. M., 2010. Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer: Cancer Lett Cancer Lett. 289(1), 71-80
• ELLIS, I. O., 2010. Intraductal proliferative lesions of the breast: morphology, associated risk and molecular biology: Mod Pathol Mod Pathol. 23 Suppl 2, S1-7
• CHEUNG, K. L., MORGAN, D. A., WINTERBOTTOM, L., RICHARDSON, H., ELLIS, I. O. and POROCK, D., 2010. A vision to optimise the management of primary breast cancer in older women: Breast Breast. 19(2), 153-5
• BARROS, F. F., POWE, D. G., ELLIS, I. O. and GREEN, A. R., 2010. Understanding the HER family in breast cancer: interaction with ligands, dimerization and treatments: Histopathology Histopathology. 56(5), 560-72
• ALESKANDARANY, M. A., RAKHA, E. A., AHMED, M. A., POWE, D. G., PAISH, E. C., MACMILLAN, R. D., ELLIS, I. O. and GREEN, A. R., 2010. PIK3CA expression in invasive breast cancer: a biomarker of poor prognosis: Breast Cancer Res Treat Breast Cancer Res Treat. 122(1), 45-53
• ALESKANDARANY, M. A., GREEN, A. R., RAKHA, E. A., MOHAMMED, R. A., ELSHEIKH, S. E., POWE, D. G., PAISH, E. C., MACMILLAN, R. D., CHAN, S., AHMED, S. I. and ELLIS, I. O., 2010. Growth fraction as a predictor of response to chemotherapy in node-negative breast cancer: Int J Cancer Int J Cancer. 126(7), 1761-9
• AGRAWAL, A., SAHA, S., ELLIS, I. O. and BELLO, A. M., 2010. Adenosquamous carcinoma of breast in a 19 years old woman: a case report: World J Surg Oncol World J Surg Oncol. 8, 44
• ABDEL-FATAH, T. M., POWE, D. G., BALL, G., LOPEZ-GARCIA, M. A., HABASHY, H. O., GREEN, A. R., REIS-FILHO, J. S. and ELLIS, I. O., 2010. Proposal for a modified grading system based on mitotic index and Bcl2 provides objective determination of clinical outcome for patients with breast cancer: J Pathol J Pathol. 222(4), 388-99
• ABDEL-FATAH, T. M., POWE, D. G., AGBOOLA, J., ADAMOWICZ-BRICE, M., BLAMEY, R. W., LOPEZ-GARCIA, M. A., GREEN, A. R., REIS-FILHO, J. S. and ELLIS, I. O., 2010. The biological, clinical and prognostic implications of p53 transcriptional pathways in breast cancers: J Pathol J Pathol. 220(4), 419-34
• MOHAMMED, R A A, ELLIS, I O, LEE, A H S and MARTIN, S G, 2009. Vascular invasion in breast cancer; an overview of recent prognostic developments and molecular pathophysiological mechanisms. Histopathology. 55(1), 1-9
• ELSHEIKH, S.E., GREEN, A.R., RAKHA, E.A., POWE, D.G., AHMED, R.A., COLLINS, H.M., SORIA, D., GARIBALDI, J.M., PAISH, C.E., AMMAR, A.A., GRAINGE, M.J., BALL, G.R., ABDELGHANY, M.K., MARTINEZ-POMARES, L., HEERY, D.M. and ELLIS, I.O., 2009. Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome Cancer Research. 69(9), 3802-3809
• KHOSHNAW, S M, GREEN, A R, POWE, D G and ELLIS, I O, 2009. MicroRNA involvement in the pathogenesis and management of breast cancer. Journal of clinical pathology. 62(5), 422-8
• PAISH, E C, GREEN, A R, RAKHA, E A, MACMILLAN, R D, MADDISON, J R and ELLIS, I O, 2009. Three-dimensional reconstruction of sentinel lymph nodes with metastatic breast cancer indicates three distinct patterns of tumour growth. Journal of clinical pathology. 62(7), 617-23
• TAN, PUAY HOON, TSE, GARY M K and ELLIS, IAN O, 2009. Special theme issue: breast pathology. Pathology. 41(1), 1-2
• RAKHA, E A, ALESKANDARANY, M, EL-SAYED, M E, BLAMEY, R W, ELSTON, C W, ELLIS, I O and LEE, A H S, 2009. The prognostic significance of inflammation and medullary histological type in invasive carcinoma of the breast. European journal of cancer (Oxford, England : 1990). 45(10), 1780-7
• POWE DG, AKHTAR G, HABASHY HO, ABDEL-FATAH T, RAKHA EA, GREEN AR and ELLIS IO, 2009. Investigating Ap-2 And Yy1 Protein Expression As A Cause Of High Her2 Gene Transcription In Breast Cancers With Discordant Her2 Gene Amplification. Breast Cancer Research : Bcr. 11(6), R90
• HAMILTON LJ, EVANS AJ, CORNFORD EJ, RAKHA EA, ELLIS IO and FOULKES WD, 2009. Will Mri Screening Deliver The Expected Survival Advantage In Brca 1 Carriers? Clinical Radiology. 64(11), 1045-7
• CHUA YL, ITO Y, POLE JCM, NEWMAN S, CHIN S, STEIN RC, ELLIS IO, CALDAS C, O'HARE MJ, MURRELL A and EDWARDS PAW, 2009. The Nrg1 Gene Is Frequently Silenced By Methylation In Breast Cancers And Is A Strong Candidate For The 8P Tumour Suppressor Gene. Oncogene. 28(46), 4041-52
• DOYLE S, EVANS AJ, RAKHA EA, GREEN AR and ELLIS IO, 2009. Influence Of E-Cadherin Expression On The Mammographic Appearance Of Invasive Nonlobular Breast Carcinoma Detected At Screening. Radiology. 253(1), 51-5
• PICKARD MR, GREEN AR, ELLIS IO, CALDAS C, HEDGE VL, MOURTADA-MAARABOUNI M and WILLIAMS GT, 2009. Dysregulated Expression Of Fau And Melk Is Associated With Poor Prognosis In Breast Cancer. Breast Cancer Research : Bcr. 11(4), R60
• GEE, J.M.W., ELORANTA, J.J., IBBITT, J.C., ROBERTSON, J.F.R., ELLIS, I.O., WILLIAMS, T., NICHOLSON, R.I. and HURST, H.C., 2009. Overexpression of TFAP2C in invasive breast cancer correlates with a poorer response to anti-hormone therapy and reduced patient survival Journal of Pathology. 217(1), 32-41
• TAN, P. H., TSE, G. M. and ELLIS, I. O., 2009. Special theme issue: breast pathology: Pathology Pathology. 41(1), 1-2
• RAKHA, E. A., GILL, M. S., EL-SAYED, M. E., KHAN, M. M., HODI, Z., BLAMEY, R. W., EVANS, A. J., LEE, A. H. and ELLIS, I. O., 2009. The biological and clinical characteristics of breast carcinoma with mixed ductal and lobular morphology: Breast Cancer Res Treat Breast Cancer Res Treat. 114(2), 243-50
• RAKHA, E. A., ELSHEIKH, S. E., ALESKANDARANY, M. A., HABASHI, H. O., GREEN, A. R., POWE, D. G., EL-SAYED, M. E., BENHASOUNA, A., BRUNET, J. S., AKSLEN, L. A., EVANS, A. J., BLAMEY, R., REIS-FILHO, J. S., FOULKES, W. D. and ELLIS, I. O., 2009. Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes: Clin Cancer Res Clin Cancer Res. 15(7), 2302-10
• RAKHA, E. A., EL-SAYED, M. E., REIS-FILHO, J. and ELLIS, I. O., 2009. Patho-biological aspects of basal-like breast cancer: Breast Cancer Res Treat Breast Cancer Res Treat. 113(3), 411-22
• RAKHA, E. A., EL-SAYED, M. E., REED, J., LEE, A. H., EVANS, A. J. and ELLIS, I. O., 2009. Screen-detected breast lesions with malignant needle core biopsy diagnoses and no malignancy identified in subsequent surgical excision specimens (potential false-positive diagnosis): Eur J Cancer Eur J Cancer. 45(7), 1162-7
• RAKHA, E. A. and ELLIS, I. O., 2009. Triple-negative/basal-like breast cancer: review: Pathology Pathology. 41(1), 40-7
• RAKHA, E. A., ALESKANDARANY, M., EL-SAYED, M. E., BLAMEY, R. W., ELSTON, C. W., ELLIS, I. O. and LEE, A. H., 2009. The prognostic significance of inflammation and medullary histological type in invasive carcinoma of the breast: Eur J Cancer Eur J Cancer. 45(10), 1780-7
• POWE, D. G., AKHTAR, G., HABASHY, H. O., ABDEL-FATAH, T., RAKHA, E. A., GREEN, A. R. and ELLIS, I. O., 2009. Investigating AP-2 and YY1 protein expression as a cause of high HER2 gene transcription in breast cancers with discordant HER2 gene amplification: Breast Cancer Res Breast Cancer Res. 11(6), R90
• POROCK, D., CHEUNG, K. L., MORGAN, D. A., WINTERBOTTOM, L., RICHARDSON, H. and ELLIS, I. O., 2009. Care of the older woman with primary breast cancer: a sign of the times?: Eur J Cancer Care (Engl) Eur J Cancer Care (Engl). 18(6), 527-9
• PICKARD, M. R., GREEN, A. R., ELLIS, I. O., CALDAS, C., HEDGE, V. L., MOURTADA-MAARABOUNI, M. and WILLIAMS, G. T., 2009. Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer: Breast Cancer Res Breast Cancer Res. 11(4), R60
• PARADISO, A., ELLIS, I. O., ZITO, F. A., MARUBINI, E., PIZZAMIGLIO, S. and VERDERIO, P., 2009. Short- and long-term effects of a training session on pathologists' performance: the INQAT experience for histological grading in breast cancer: J Clin Pathol J Clin Pathol. 62(3), 279-81
• PAISH, E. C., GREEN, A. R., RAKHA, E. A., MACMILLAN, R. D., MADDISON, J. R. and ELLIS, I. O., 2009. Three-dimensional reconstruction of sentinel lymph nodes with metastatic breast cancer indicates three distinct patterns of tumour growth: J Clin Pathol J Clin Pathol. 62(7), 617-23
• OKUNADE, G., GREEN, A. R., YING, M., AGRAWAL, A., PAISH, E. C., ALESKANDRANY, M., WINTERBOTTOM, L., HASSELL, K., MORGAN, D. A., ELLIS, I. O. and CHEUNG, K. L., 2009. Biological profile of oestrogen receptor positive primary breast cancers in the elderly and response to primary endocrine therapy: Crit Rev Oncol Hematol Crit Rev Oncol Hematol. 72(1), 76-82
• MOHAMMED, R. A., ELLIS, I. O., LEE, A. H. and MARTIN, S. G., 2009. Vascular invasion in breast cancer; an overview of recent prognostic developments and molecular pathophysiological mechanisms: Histopathology Histopathology. 55(1), 1-9
• MOHAMMED, R. A., ELLIS, I. O., ELSHEIKH, S., PAISH, E. C. and MARTIN, S. G., 2009. Lymphatic and angiogenic characteristics in breast cancer: morphometric analysis and prognostic implications: Breast Cancer Res Treat Breast Cancer Res Treat. 113(2), 261-73
• KHOSHNAW, S. M., GREEN, A. R., POWE, D. G. and ELLIS, I. O., 2009. MicroRNA involvement in the pathogenesis and management of breast cancer: J Clin Pathol J Clin Pathol. 62(5), 422-8
• HAMILTON, L. J., EVANS, A. J., CORNFORD, E. J., RAKHA, E. A., ELLIS, I. O. and FOULKES, W. D., 2009. Will MRI screening deliver the expected survival advantage in BRCA 1 carriers?: Clin Radiol Clin Radiol. 64(11), 1045-7
• GREEN, A. R., YOUNG, P., KRIVINSKAS, S., RAKHA, E. A., CLAIRE PAISH, E., POWE, D. G. and ELLIS, I. O., 2009. The expression of ERalpha, ERbeta and PR in lobular carcinoma in situ of the breast determined using laser microdissection and real-time PCR: Histopathology Histopathology. 54(4), 419-27
• GREEN, A. R., KRIVINSKAS, S., YOUNG, P., RAKHA, E. A., PAISH, E. C., POWE, D. G. and ELLIS, I. O., 2009. Loss of expression of chromosome 16q genes DPEP1 and CTCF in lobular carcinoma in situ of the breast: Breast Cancer Res Treat Breast Cancer Res Treat. 113(1), 59-66
• FOULKES, W. D., GRAINGE, M. J., RAKHA, E. A., GREEN, A. R. and ELLIS, I. O., 2009. Tumor size is an unreliable predictor of prognosis in basal-like breast cancers and does not correlate closely with lymph node status: Breast Cancer Res Treat Breast Cancer Res Treat. 117(1), 199-204
• DOYLE, S., EVANS, A. J., RAKHA, E. A., GREEN, A. R. and ELLIS, I. O., 2009. Influence of E-cadherin expression on the mammographic appearance of invasive nonlobular breast carcinoma detected at screening: Radiology Radiology. 253(1), 51-5
• CHUA, Y. L., ITO, Y., POLE, J. C., NEWMAN, S., CHIN, S. F., STEIN, R. C., ELLIS, I. O., CALDAS, C., O'HARE, M. J., MURRELL, A. and EDWARDS, P. A., 2009. The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene: Oncogene Oncogene. 28(46), 4041-52
• AU-YONG, I. T., EVANS, A. J., TANEJA, S., RAKHA, E. A., GREEN, A. R., PAISH, C. and ELLIS, I. O., 2009. Sonographic correlations with the new molecular classification of invasive breast cancer: Eur Radiol Eur Radiol. 19(10), 2342-8
• ELLIS, P., BARRETT-LEE, P., JOHNSON, L., CAMERON, D., WARDLEY, A., O'REILLY, S., VERRILL, M., SMITH, I., YARNOLD, J., COLEMAN, R., EARL, H., CANNEY, P., TWELVES, C., POOLE, C., BLOOMFIELD, D., HOPWOOD, P., JOHNSTON, S., DOWSETT, M., BARTLETT, J.M.S., ELLIS, I., PECKITT, C., HALL, E. and BLISS, J.M., 2009. Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open-label, phase III, randomised controlled trial Lancet. 373(9676), 1681-1692
• RAKHA, EMAD A, EL-SAYED, MAYSA E, POWE, DESMOND G, GREEN, ANDREW R, HABASHY, HANY, GRAINGE, MATTHEW J, ROBERTSON, JOHN F R, BLAMEY, ROGER, GEE, JULIA, NICHOLSON, ROBERT I, LEE, ANDREW H S and ELLIS, IAN, 2008. Invasive lobular carcinoma of the breast: response to hormonal therapy and outcomes. European Journal of Cancer. 44(1), 73-83
• SPENDLOVE, I., AL-ATTAR, A., WATHERSTONE, O., WEBB, T.M., ELLIS, E.O., LONGMORE, G.D. and SHARP, T.V., 2008. Differential subcellular localisation of the tumour suppressor protein LIMD1 in breast cancer correlates with patient survival International Journal of Cancer. 123(10), 2247-2253
• RAKHA, E.A., EL-SAYED, M.E., LEE, A.H.S., ELSTON, C.W., GRAINGE, M.J., HODI, Z., BLAMEY, R.W. and ELLIS, I.O., 2008. Prognostic significance of Nottingham histologic grade in invasive breast carcinoma Journal of Clinical Oncology. 26(19), 3153-3158
• GREEN,, KRIVINSKAS,, YOUNG,, RAKHA,, PAISH,, POWE, and ELLIS,, 2008. Loss of expression of chromosome 16q genes DPEP1 and CTCF in lobular carcinoma in situ of the breast. Breast Cancer Research and Treatment.
• RAKHA, EMAD A, EL-SHEIKH, SOMAIA E, KANDIL, MONA A, EL-SAYED, MAYSA E, GREEN, ANDREW R and ELLIS, IAN O, 2008. Expression of BRCA1 protein in breast cancer and its prognostic significance. Human pathology. 39(6), 857-65
• RAKHA,, EL-SAYED,, REIS-FILHO, and ELLIS,, 2008. Patho-biological aspects of basal-like breast cancer. Breast Cancer Research and Treatment.
• ZHU, X., MULCAHY, L.A., MOHAMMED, R.A., LEE, A.H., FRANKS, H.A., KILPATRICK, L., YILMAZER, A., PAISH, E.C., ELLIS, I.O., PATEL, P.M. and JACKSON, A.M., 2008. IL-17 expression by breast-cancer-associated macrophages: IL-17 promotes invasiveness of breast cancer cell lines Breast Cancer Research. 10(6), R95
• EL-SAYED ME, RAKHA EA, REED J, LEE AHS, EVANS AJ and ELLIS IO, 2008. Predictive Value Of Needle Core Biopsy Diagnoses Of Lesions Of Uncertain Malignant Potential (B3) In Abnormalities Detected By Mammographic Screening. Histopathology. 53(6), 650-7
• TENNANT SL, EVANS A, HAMILTON LJ, JAMES J, LEE AHS, HODI Z, ELLIS IO, RAKHA EA and WILSON ARM, 2008. Vacuum-Assisted Excision Of Breast Lesions Of Uncertain Malignant Potential (B3) - An Alternative To Surgery In Selected Cases. Breast (Edinburgh, Scotland). 17(6), 546-9
• RAKHA EA, EL-SAYED ME, REIS-FILHO JS and ELLIS IO, 2008. Expression Profiling Technology: Its Contribution To Our Understanding Of Breast Cancer. Histopathology. 52(1), 67-81
• FANSHAWE TR, LYNCH AG, ELLIS IO, GREEN AR and HANKA R, 2008. Assessing Agreement Between Multiple Raters With Missing Rating Information, Applied To Breast Cancer Tumour Grading. Plos One. 3(8), e2925
• SHAABAN, A.M., GREEN, A.R., KARTHIK, S., ALIZADEH, Y., HUGHES, T.A., HARKINS, L., ELLIS I.O., ROBERTSON, J.F., PAISH, E.C., SAUNDERS, P.T.K., GROOME, N.P. and SPEIRS, V., 2008. Nuclear and cytoplasmic expression of ERβ1, ERβ2, and ERβ5 identifies distinct prognostic outcome for breast cancer patients Clinical Cancer Research. 14(16), 5228-5235
• WEBSTER, L. R., LEE, S. F., RINGLAND, C., MOREY, A. L., HANBY, A. M., MORGAN, G., BYTH, K., MOTE, P. A., PROVAN, P. J., ELLIS, I. O., GREEN, A. R., LAMOURY, G., RAVDIN, P., CLARKE, C. L., WARD, R. L., BALLEINE, R. L. and HAWKINS, N. J., 2008. Poor-prognosis estrogen receptor-positive breast cancer identified by histopathologic subclassification: Clin Cancer Res Clin Cancer Res. 14(20), 6625-33
• WALKER, R. A., BARTLETT, J. M., DOWSETT, M., ELLIS, I. O., HANBY, A. M., JASANI, B., MILLER, K. and PINDER, S. E., 2008. HER2 testing in the UK: further update to recommendations: J Clin Pathol J Clin Pathol. 61(7), 818-24
• TENNANT, S. L., EVANS, A., HAMILTON, L. J., JAMES, J., LEE, A. H., HODI, Z., ELLIS, I. O., RAKHA, E. A. and WILSON, A. R., 2008. Vacuum-assisted excision of breast lesions of uncertain malignant potential (B3) - an alternative to surgery in selected cases: Breast Breast. 17(6), 546-9
• TANEJA, S., EVANS, A. J., RAKHA, E. A., GREEN, A. R., BALL, G. and ELLIS, I. O., 2008. The mammographic correlations of a new immunohistochemical classification of invasive breast cancer: Clin Radiol Clin Radiol. 63(11), 1228-35
• SPEIRS, V., GREEN, A. R., HUGHES, T. A., ELLIS, I. O., SAUNDERS, P. T. and SHAABAN, A. M., 2008. Clinical importance of estrogen receptor beta isoforms in breast cancer: J Clin Oncol J Clin Oncol. 26(35), 5825; author reply 5825-6
• REIS-FILHO, J. S., NATRAJAN, R., VATCHEVA, R., LAMBROS, M. B., MARCHIO, C., MAHLER-ARAUJO, B., PAISH, C., HODI, Z., EUSEBI, V. and ELLIS, I. O., 2008. Is acinic cell carcinoma a variant of secretory carcinoma? A FISH study using ETV6'split apart' probes: Histopathology Histopathology. 52(7), 840-6
• RAMPAUL, R. S., DALE, O. T., MITCHELL, M., BLAMEY, R. W., MACMILLAN, R. D., ROBERTSON, J. F. and ELLIS, I. O., 2008. Incidence of intramammary nodes in completion mastectomy specimens after axillary node sampling: implications for breast conserving surgery: Breast Breast. 17(2), 195-8
• RAKHA, E. A., REIS-FILHO, J. S. and ELLIS, I. O., 2008. Basal-like breast cancer: a critical review: J Clin Oncol J Clin Oncol. 26(15), 2568-81
• RAKHA, E. A., REIS-FILHO, J. S. and ELLIS, I. O., 2008. Impact of basal-like breast carcinoma determination for a more specific therapy: Pathobiology Pathobiology. 75(2), 95-103
• RAKHA, E. A., EL-SHEIKH, S. E., KANDIL, M. A., EL-SAYED, M. E., GREEN, A. R. and ELLIS, I. O., 2008. Expression of BRCA1 protein in breast cancer and its prognostic significance: Hum Pathol Hum Pathol. 39(6), 857-65
• RAKHA, E. A., EL-SAYED, M. E., REIS-FILHO, J. S. and ELLIS, I. O., 2008. Expression profiling technology: its contribution to our understanding of breast cancer: Histopathology Histopathology. 52(1), 67-81
• RAKHA, E. A., EL-SAYED, M. E., POWE, D. G., GREEN, A. R., HABASHY, H., GRAINGE, M. J., ROBERTSON, J. F., BLAMEY, R., GEE, J., NICHOLSON, R. I., LEE, A. H. and ELLIS, I. O., 2008. Invasive lobular carcinoma of the breast: response to hormonal therapy and outcomes: Eur J Cancer Eur J Cancer. 44(1), 73-83
• RAKHA, E. A., EL-SAYED, M. E., MENON, S., GREEN, A. R., LEE, A. H. and ELLIS, I. O., 2008. Histologic grading is an independent prognostic factor in invasive lobular carcinoma of the breast: Breast Cancer Res Treat Breast Cancer Res Treat. 111(1), 121-7
• RAKHA, E. A., ELLIS, I. O. and REIS-FILHO, J. S., 2008. Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas): Mod Pathol Mod Pathol. 21(8), 1060-1; author reply 1061-2
• MENON, S., PORTER, G. J., EVANS, A. J., ELLIS, I. O., ELSTON, C. W., HODI, Z. and LEE, A. H., 2008. The significance of lobular neoplasia on needle core biopsy of the breast: Virchows Arch Virchows Arch. 452(5), 473-9
• LUCK, A. A., EVANS, A. J., JAMES, J. J., RAKHA, E. A., PAISH, E. C., GREEN, A. R. and ELLIS, I. O., 2008. Breast carcinoma with basal phenotype: mammographic findings: AJR Am J Roentgenol AJR Am J Roentgenol. 191(2), 346-51
• LUCK, A. A., EVANS, A. J., GREEN, A. R., RAKHA, E. A., PAISH, C. and ELLIS, I. O., 2008. The influence of basal phenotype on the metastatic pattern of breast cancer: Clin Oncol (R Coll Radiol) Clin Oncol (R Coll Radiol). 20(1), 40-5
• LEE, A. H., HODI, Z. and ELLIS, I. O., 2008. False-negative assessment of oestrogen receptor on needle core biopsy of invasive carcinoma of the breast: J Clin Pathol J Clin Pathol. 61(2), 239-40
• LEE, A. H. and ELLIS, I. O., 2008. The Nottingham prognostic index for invasive carcinoma of the breast: Pathol Oncol Res Pathol Oncol Res. 14(2), 113-5
• HABASHY, H. O., POWE, D. G., RAKHA, E. A., BALL, G., PAISH, C., GEE, J., NICHOLSON, R. I. and ELLIS, I. O., 2008. Forkhead-box A1 (FOXA1) expression in breast cancer and its prognostic significance: Eur J Cancer Eur J Cancer. 44(11), 1541-51
• GREEN, A. R., BURNEY, C., GRANGER, C. J., PAISH, E. C., EL-SHEIKH, S., RAKHA, E. A., POWE, D. G., MACMILLAN, R. D., ELLIS, I. O. and STYLIANOU, E., 2008. The prognostic significance of steroid receptor co-regulators in breast cancer: co-repressor NCOR2/SMRT is an independent indicator of poor outcome: Breast Cancer Res Treat Breast Cancer Res Treat. 110(3), 427-37
• FANSHAWE, T. R., LYNCH, A. G., ELLIS, I. O., GREEN, A. R. and HANKA, R., 2008. Assessing agreement between multiple raters with missing rating information, applied to breast cancer tumour grading: PLoS One PLoS One. 3(8), e2925
• ELSHEIKH, S. E., GREEN, A. R., RAKHA, E. A., SAMAKA, R. M., AMMAR, A. A., POWE, D., REIS-FILHO, J. S. and ELLIS, I. O., 2008. Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype: Br J Cancer Br J Cancer. 99(2), 327-34
• ELSHEIKH, S., GREEN, A. R., ALESKANDARANY, M. A., GRAINGE, M., PAISH, C. E., LAMBROS, M. B., REIS-FILHO, J. S. and ELLIS, I. O., 2008. CCND1 amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome: Breast Cancer Res Treat Breast Cancer Res Treat. 109(2), 325-35
• EL-SAYED, M. E., RAKHA, E. A., REED, J., LEE, A. H., EVANS, A. J. and ELLIS, I. O., 2008. Audit of performance of needle core biopsy diagnoses of screen detected breast lesions: Eur J Cancer Eur J Cancer. 44(17), 2580-6
• EL-SAYED, M. E., RAKHA, E. A., REED, J., LEE, A. H., EVANS, A. J. and ELLIS, I. O., 2008. Predictive value of needle core biopsy diagnoses of lesions of uncertain malignant potential (B3) in abnormalities detected by mammographic screening: Histopathology Histopathology. 53(6), 650-7
• COOKE, S. L., POLE, J. C., CHIN, S. F., ELLIS, I. O., CALDAS, C. and EDWARDS, P. A., 2008. High-resolution array CGH clarifies events occurring on 8p in carcinogenesis: BMC Cancer BMC Cancer. 8, 288
• CHEUNG, K. L., WONG, A. W., PARKER, H., LI, V. W., WINTERBOTTOM, L., MORGAN, D. A. and ELLIS, I. O., 2008. Pathological features of primary breast cancer in the elderly based on needle core biopsies--a large series from a single centre: Crit Rev Oncol Hematol Crit Rev Oncol Hematol. 67(3), 263-7
• ABDULKADER, M., ELLIS, I. O., SCHOLEFIELD, J. H. and KAYE, P. V., 2008. Extramammary Paget's possibly arising from a non-invasive rectal adenoma: Histopathology Histopathology. 53(2), 228-31
• ABDEL-FATAH, T. M., POWE, D. G., HODI, Z., REIS-FILHO, J. S., LEE, A. H. and ELLIS, I. O., 2008. Morphologic and molecular evolutionary pathways of low nuclear grade invasive breast cancers and their putative precursor lesions: further evidence to support the concept of low nuclear grade breast neoplasia family: Am J Surg Pathol Am J Surg Pathol. 32(4), 513-23
• DOWSETT, M., ALLRED, C., KNOX, J., QUINN, E., SALTER, J., WALE, C., CUZICK, J., HOUGHTON, J., WILLIAMS, N., MALLON, E., BISHOP, H., ELLIS, I., LARSIMONT, D., SASANO, H., CARDER, P., CUSSAC, A.L., KNOX, F., SPEIRS, V., FORBES, J. and BUZDAR, A., 2008. Relationship between quantitative estrogen and progesterone receptor expression and human epidermal growth factor receptor 2 (Her-2) status with recurrence in the Arimidex, Tamoxifen, Alone or in Combination Trial Journal Of Clinical Oncology. 26(7), 1059-1065