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Nikola Sprigg

Professor of Stroke Medicine, Faculty of Medicine & Health Sciences

Contact

  • workRoom B60 Clinical Sciences Building
    Nottingham City Hospital
    Hucknall Road
    Nottingham
    NG5 1PB
    UK
  • work0115 823 1778
  • fax0115 823 1767

Biography

Professor of Stroke Medicine at Nottingham University, and also an Honorary Consultant Physician in Stroke Medicine for Nottingham University Hospitals NHS Trust.

Prior to taking up post as Associate Professor, I undertook general medical training in Sheffield, Leicester and Nottingham, with a specialist certificate of training in Geriatrics and Stroke.

Expertise Summary

Current interests include developing treatments to improve recovery after stroke, treatment of haemorrhagic stroke, quality of life after stroke, management of blood pressure after stroke, use of hypothermia in acute ischaemic stroke, anti-platelet treatment for the secondary prevention of stroke, fatigue and rehabilitation after stroke.

Chief Investigator of TICH-2 (NIHR HTA funded) a phase III study testing tranexamic acid in intracerebral haemorrhage, and of STEMS3 (NIHR RfPB funded), a phase II study of G-CSF and physiotherapy in chronic stroke, and National coordinator of EuroHyp-1, a European, multi-centre, phase III, clinical trial of hypothermia after stroke.

I am Stroke Lead for the East Midlands CRN.

Teaching Summary

I enjoy teaching and regularly receive positive feedback from teaching delivered to medical students, post graduates, allied health professionals and stroke survivors.

Research Summary

My current interests include developing treatments to improve recovery after stroke, particularly intracerebral haemorhage, quality of life after stroke, management of blood pressure after stroke,… read more

Selected Publications

Current Research

My current interests include developing treatments to improve recovery after stroke, particularly intracerebral haemorhage, quality of life after stroke, management of blood pressure after stroke, use of hypothermia in acute ischaemic stroke, anti-platelet treatment for the secondary prevention of stroke, fatigue and rehabiliation after stroke.

I am CI of TICH-2 (HTA funded) a phase III study testing tranexamic acid in intracerebral haemorrhage, and of STEMS3 (RfPB funded), a phase II study of G-CSF and/or physiotherapy in chronic stroke, and National coordinator of EuroHyp-1, a European, multi-centre, phase III, clinical trial of hypothermia after stroke. I am a member of the BASP scientific committee and adjudicate SAEs and outcomes in ENOS and TARDIS. I was on the DMC for the MRC funded STEMS2 study and am on the DMC for the ongoing RfPB Neurovascular Imaging in Patients with Carotid Artery Disease study and RATULS study.

I am Clinical Lead for Trent Stroke Research Network.

Past Research

I studied stroke recovery and the management of blood pressure in acute stroke as part of my Doctorate of Medicine, Clinical Studies of stroke recovery and potential enhancement with pharmacological intervention or stem cell mobilisation.

Future Research

I would be interested in collaborating Nationally or Internationally on areas involving acute stroke, recovery after stroke alon the lines of my research interests.

More recently this includes visual problems after stroke, and pre-eclampsia as a risk factor for stroke.

School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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