School of Medicine
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Research Facilities and Services

The School of Medicine is pleased to make available some of its world-class facilities, latest technologies and specialist services to other departments and external researchers. Services- and facility-related queries should be made to the respective contact persons.

University resource

research facilities
 

 

Clinical & Research Facilities
Name and description of service or facilityDepartmentContact

NUHT Children's Clinical Research Facility (Outpatient)

Child Health, Obstetrics and Gynaecology Prof Alan Smyth

NIHR Nottingham BRC - Digestive Diseases

NIHR Nottingham BRC Dr Tiffany Hamilton,
Maria Matthews

NIHR Nottingham BRC - Otology and Hearing

Adult and Paediatric Audiology Facility:

Two state-of-the art sound booths, adjacent control rooms, 4 sound attenuated Test Rooms and a Child and Family Lab housing state-of-the-art video and audio equipment for observing and recording assessment and intervention sessions

NIHR Nottingham BRC Vicenta Rose

Flow Cytometry Service

School of Life Sciences Register here

Medical Imaging Unit

3T & 1.5T MRI with aestiva anaesthetic equipment and hyperpolarised gas

School of Medicine Michael Barlow

Clinical Research Facility

4 bed ward and 4 individual side rooms available for clinical research, limited lab facilities for sample preparation

School of Medicine Sarah Wolfe

Pre-clinical models of cancer

For drug testing and target discovery/validation

Cancer Biology Unit Dr Phil Clarke

Dedicated Human Stem Cell Culture Suite

12 Class II cabinets purpose-designed and dedicated to adult and human embryonic stem cells

Stem Cell Biology Prof Chris Denning

Electrophysiology facilities

Multi-electrode arrays that enable non-invasive recordings from cardiac and neural cells

Stem Cell Biology Prof Chris Denning

Chick Embryo Culture and Microinjection

System for evaluating stem cell fate

Stem Cell Biology Dr Virginie Sottile

Radiation Biology Facility

Ionising Radiation Cabinet

 Cancer & Stem Cells (Translational & Radiation Biology research)  Dr Stewart Martin

 

Clinical & Research Equipment* (*Links below take you to the University's Kit Catalogue's webpage)

Name and description of equipmentDepartmentContact

Autoclave (100L) floor mounted, front loading autoclave used for the sterilization of lab equipment. The machine has a cycle time at 121oC of 40 mins and is programmable via internal software.

Clinical Sciences Building (CSB) - Nottingham City Hospital site (CHN) Anne Hill, Lisa Mazengarb

Autoclave (150L) floor mounted, front loading autoclave used for the sterilization of lab equipment. The machine has a cycle time at 121oC of 15 mins and is programmable via internal software

CSB - CHN Anne Hill, Lisa Mazengarb

Gulmay (Xstrahl) RS225 Ionising Radiation Cabinet

Cancer & Stem Cells (Translational & Radiation Biology research) Dr Stewart Martin

Tecan Robotic Cell Culture Platform

Fully automated human pluripotent stem cell culture and differentiation to hepatocytes, neural progenitors and cardiomyocytes

Oncology - Stem Cell Biology - University Park (UP) Prof Chris Denning

Beckman Scintillation counter

Benchtop microplate scintillation and luminescence counter

Cancer & Stem Cells - CHN Rob Moss, Julie Stanley

Bio-plex 200 multiplexing platform 1/2

Versatile multiplexing platform capable of performing qualitative and quantitative analysis of proteins and nucleic acids in a variety of sample matrices

Cancer & Stem Cells - CHN Garry Meakin, Prof Lindy Durrant

Bio-plex 200 multiplexing platform 2/2

Versatile multiplexing platform capable of performing qualitative and quantitative analysis of proteins and nucleic acids in a variety of sample matrices

Cancer & Stem Cells - CHN Dr Ian Spendlove, Prof Poulam Patel

Biochrom Amino Acid Analyser

Measures concentration of Amino Acids in plasma and other fluids

GEM - Derby Kenneth Smith, Debbie Rankin

Beckman Coulter Avanti J-30I – Ultracentrifuge

This is a refrigerated high-speed centrifuge (Beckman Avanti J-301) with three rotors suitable for many general centrifugal operations, for example sedimentation of proteins, nucleic acids, subcellular organelles, blood preparations and gradient separations.

Respiratory Medicine - QMC Emily Hodge, Julie Hawley

Breath Analysis Mass Spectrometer

For the measurement of isotope ratios of 13/12D, 15/14N and 18/16O as fixed gases, also 2/1H as acetylene; Amino acid, glucose and fat oxidation studies in health and disease in humans; Breath test analyses e.g. Urea breath test, liver function tests, gut motility and absorption studies

GEM - Derby Kenneth Smith, Anna Selby

BD FACS Canto Machine

Used for measuring cellular proteins

CSB – CHN Claire Seedhouse, Monica Pallis

Fibroscan 502 Touch

Transient elastography - assessment of liver stiffness in patients with suspected (clinical application) or known (research application) liver disease

NDDC – QMC Prof Guru Aithal

Flexstation 3

Fluorescence absorbance, fluorescence intensity, fluorescence polarization, and time-resolved fluorescence assays

Respiratory Medicine - QMC

Bo Liu, Julie Hawley

Flexstation II

Biomarker identification and targeting

Cancer & Stem Cells – Cancer Biology Phil Clarke

Fluorescent Microscope Nikon Diaphot 300

Inverted fluorescence microscope with epifluorescence. The item currently has filters set for FITC, Rhodamine and DAPI for the imaging of green, red and blue fluorescing samples respectively. The machine is used for immunofluorescence and immunohistochemical studies.

Respiratory Medicine - QMC Debbie Clements, Julie Hawley

Guava easyCyte 8HT Base

Bench top sized flow cytometer offering absolute cell counts

Centre for Biomolecular Sciences (UP) Prof Chris Denning, Jayson Bispham

High Resolution Manometry

Oesophageal and Anorectal Manometry

NDDC - GI Surgery Jeff Wright, Debbie Bush

IR Western Blot Detection system

Used for detecting protein expressions on blots or in cells

CSB - CHN Ulvi Bayraktutan, Kamini Vashisht

ISQ Gas Chromatograph Mass Spectrometer

Protein turnover and amino acid, fatty acid and glucose metabolism in humans in health and disease using stable isotope tracers

GEM - Derby Ken Smith, Daniel Wilkinson

Lunar Prodigy Dexa

Dual-energy X-ray absorptiometry (DEXA) machine is a X-ray imagining and analysis tool used to measure bone, muscle and/or fat density

GEM - Derby Kenneth Smith, Margaret Baker

MAGPIX multiplexing platform

Qualitative and quantitative analysis of proteins and nucleic acids in a variety of sample matrices

GEM - Derby Saoirse O’Sullivan

Mass Spectrometer Thermo Finnigan Trace DSQ

Fuel oxidation studies in humans

GEM - Derby Kenneth Smith, Anna Selby

Neo-natal Incubator

MRI imaging of infants

Child Health Prof Helen Budge, Shalini Ojha
Nikon microscope Eclipse Ti

Inverted Imaging System is a widefield inverted microscope. The system images in multi-colour and in 3D. The system is currently used for 3D cell culture and model development.
Cancer Biology Phil Clarke

Nikon Ti-E/A1 Inverted Confocal microscope

Fully motorised stage, A1 Confocal Detector

CSB - CHN Dan Duthie, Jo Porte

NMR microimager for hyperpolarised noble gases

Development of hyperpolarised pulmonary noble gas MRI

Sir Peter Mansfield Imaging Centre  Prof Thomas Meersman, Dr Galina Pavlovskaya

NMR spectrometer for hyperpolarised noble gases

Development of hyperpolarised pulmonary noble gas MRI

Sir Peter Mansfield Imaging Centre

Prof Thomas Meersman, Dr Galina Pavlovskaya

Optical Tomography System

Cortical responses in deaf participants with cochlear implants

NIHR Nottingham Biomedical Research Centre Dr Doug Hartley, Rebecca Dewey

Pain & Sensory Evaluation System (fMRI compatible)

Contact Heat-Evoked Potential Stimulator is an advanced thermal stimulator for pain evoked-potential equipped with functional MRI (fMRI) capabilities

Sir Peter Mansfield Imaging Centre (UP) Tiffany Hamilton, Susan Francis

Precision Liquid Handling Robot 10641541

Automated pipetting of liquid into 96 well microtitre plates

CSB - CHN Alan Gilmour,  Caroline Chapman

Research coil array

MR Volume Resonator and Phased Array Research coil for use with Hyperpolarized Xenon in 1.5T MRI whole body scanner

Medical Imaging Unit Mike Barlow, Brett Haywood

Rheometer with magnetic thrust bearing technology

Rheology of biofluids

Sir Peter Mansfield Imaging Centre (UP) Prof Thomas Meersman, Galina Pavlovskaya

Spinning Disk Confocal Microscope

This high speed imaging system has lower toxicity and photobleaching than conventional scanning microscopes, making it ideal for imaging live cells. The system is equipped with an environmental chamber (temperature and C02 controlled) and an electronic stage with memory capability.

Respiratory Medicine- QMC Charlotte Billington,
Julie Hawley

Stratagene MX3005P - Real time PCR

Real-time thermal cycler for QPCR (Quantitative PCR) containing 5 filters

Respiratory Medicine - MC Debbie Clements, Julie Hawley

Thermo Finnigan MD800 Mass Spectrometer

Fuel oxidation studies in humans

GEM - Derby Kenneth Smith, Anna Selby

Thermo Finnigan Delta Plus X Mass Spectrometer

Fuel oxidation studies in humans

GEM - Derby Kenneth Smith, Anna Selby

Thermo Finnigan Delta Plus XL Mass Spectrometer

Fuel oxidation studies in humans

GEM - Derby Kenneth Smith, Anna Selby

Thermo Finnigan Delta V Advantage Mass Spectrometer

Gas chromatograph-pyrolysis-isotope ratio mass spectrometer. Deuterium analysis Human Metabolic Studies - Protein turnover, Energy Expenditure

GEM - Derby Kenneth Smith, Dan Wilkinson

Thermo Finnigan MD800 Gas Chromatograph Mass Spectrometer

Fuel oxidation studies in humans

GEM - Derby Kenneth Smith, Anna Selby

TSQ Gas Chromatograph Mass Spectrometer

Protein Turnover and amino acid, fatty acid and glucose metabolism in humans in health and disease using stable isotope tracers 

GEM - Derby Kenneth Smith, Dan Wilkinson

Ultracentrifuge

Spinning and separation, developing gradients

GEM - Derby Kenneth Smith, Debbie Rankin

Ultrasound

Ultrasound for muscular skeletal, visceral and contrast enhanced ultrasound imaging

GEM - Derby John Williams, Beth Phillips

Ultrasound

Digital Ultrasound Ectomograph - Used to scan and analyse muscle architecture 

GEM - Derby Marco Narici, Kenneth Smith

Upright Fluorescent microscope

Nikon 90i Fluorescent histology upright microscope with B&W and colour camera + imaging software

Respiratory Medicine - CHN Dan Duthie, Jo Porte

XeCT Enhancer System

CT image enhancement and measurement of Cerebral Blood Flow

Stroke – NUHT Radiology Wim Clarke, Prof Philip Bath

 

 

Clinical and Research Services
Name of serviceDepartment Contact

NIHR Research Design Service East Midlands

Free advice on research design to researchers in the East Midlands

School of Medicine rds-eastmidlands@nottingham.ac.uk   

PRIMIS

Primary care health informatics products and services

Primary Care  enquiries@primis.nottingham.ac.uk  

Statistics Advice Clinic (login to Workspace required)

Weekly drop-in clinic for staff and PGR students in the School of Medicine

School of Medicine andrea.venn@nottingham.ac.uk 

Interdisciplinary Collaboration in Systems Medicine (ICSM)

Optimising mechanical ventilatory strategy in shock states and critical pulmonary illness

Alveolar recruitment in ARDS

Quantifying gas exchange defects in critical pulmonary illness

Apnoea, hypoventilation and hypoxaemia

Clinical Neuroscience - Anaesthesia & Intensive Care Prof Jonathan Hardman
Qualitative methodology, intervention design and patient safety Clinical Neuroscience - Anaesthesia & Intensive Care Prof Ravi Mahajan

Nottingham Clinical Trials Unit

UK Clinical Research Collaboration (UKCRC) registered CTU

Nottingham Health Science Partners Jacqueline Stanesby, or ctu@nottingham.ac.uk  

GI Motility Unit

Facility offering a research and clinical GI diagnostic service

Investigations include oesophageal high resolution impedance manometry, 24hr oesophageal impedance/pH, Bravo pH (research only), sphincter of Oddi manometry, anal manometry and 3D endoanal ultrasound

NDDC – GI Surgery (QMC) Upper GI – Dr Jeff Wright

Lower GI – Mrs Debbie Bush

 

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School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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