Current
Research Projects & Publications
with Dr Carl Stevenson (SB campus University of Nottingham); Dr David
Halliday (University of York)
Stevenson CS, Meredith JP, Spicer CH, Mason R
& Marsden CA (2009) Early life programming of innate fear and
cue-conditioned fear learning in adult female rats.
Behavioural Brain Research 198: 51-57.
Stevenson CW, Goodwin PE, Tunstall B, Spicer
CH, Marsden CA, Mason R (2009) Neonatal maternal separation alters
reward-related ultrasonic vocalizations in rat dams Behavioural Brain Research 200:
232-236.
Stevenson
CW, Halliday DM, Marsden CA, Mason R (2008) Early
life programming of hemispheric lateralization and synchronization in the adult
medial prefrontal cortex. Neuroscience 155: 852-863. pdf
Stevenson
CW, Marsden CA, Mason R (2008) Early life stress causes FG-7142 induced
corticolimbic dysfunction in adulthood. Brain
Res 1193: 43-50. pdf
Stevenson
CW, Halliday DH, Marsden CA, Mason R (2007) Systemic
administration of the benzodiazepine receptor partial inverse agonist FG-7142
disrupts corticolimbic network interactions
Synapse
61: 646-663. pdf
Mason R, Halliday D,
Stevenson CW,
Meredith JP, Mason R & Marsden CA (2006) Effects of early adversity on
aversive learning in the adult rat.
Stevenson CW,
Halliday DH, Marsden CA, Mason R (2005) Effects of early maternal separation on
prefrontal cortex and amygdala neural activity in response to stress in the
adult rat. Soc Neurosci
Abstracts
Stevenson CW, Marsden CA and Mason R (2005) Disruption
of the functional connectivity between the prefrontal cortex and basolateral amygdala by a pharmacological stressor in the
rat. British
Neurosci Assoc Abs.
Neuronal ensemble interactions in mPFC, hippocampus and ventral tegmental
area: Sensory gating neurobiology & sites of action of antipsychotic drugs
with C Spicer; Dr Dilshani Dissanayake, Dr Margarita
Zachariou, Ioannis Taxidis, Prof Stephen
Coombes, Dr Markus Owen
Taxidis
J, Coombes S, Mason R & Owen MR (2011) Modeling
Sharp Wave - Ripple Complexes Through a CA3-CA1 Network Model With Chemical
Synapses Hippocampus xxx: xxx-xxx pdf
Taxidis
J, Coomber B, Mason, R & Owen M (2010) Assessing cortico-hippocampal
functional connectivity under anaesthesia and kainic acid using generalized
partial directed coherence Biol.
Cybernetics
102: 327-340 pdf
Dissanayake WDN, Zachariou, M, Marsden CA, & Mason, R (2009) Effects of phencyclidine on
auditory gating in the rat hippocampus and the medial prefrontal cortex Brain Research 1298: 153-160 pdf
Dissanayake WDN, Zachariou,
M,
Zachariou, M, Dissanayake WDN, Owen MR, Mason, R &
Coombes, S (2008) Sensory gating and its modulation by cannabinoids:
electrophysiological, computational and
mathematical analysis. Cognitive Neurodynamics 2:
159-170 pdf
Zachariou M, Dissanayake WND, Owen MR, Mason
R and Coombes S (2007)
The Role of Cannabinoids in the Neurobiology of Sensory Gating: A firing rate
model study. Neurocomputing 70: 1902-1906. pdf
Dissanayake WDN, Zachariou M, Marsden CA
& Mason R (2007) Effect of phencyclidine on auditory evoked
potentials in the rat medial prefrontal cortex and hippocampus J. Psychopharmacol.
Dissanayake WDN, CA Marsden CA & Mason R, (2006)
Effects of phencyclidine on hippocampal sensory gating under isoflurane
anaesthesia in the rat Proc Brit J Pharmacol. www.pA2online.org pdf poster
Dissanayake WDN, Zachariou M, CA Marsden
CA & Mason R, (2006)
Abolition of sensory gating by the cannabinoid WIN55,212-2
in the rat hippocampus J. Psychopharmacol. 20 (5) A45. pdf
Poster
Suckling
JM, Kew JNC, Harries, M & Mason R (2003) Apomorphine
suppresses neuronal activity in ventral tegmental area and prefrontal cortex. Soc. Neurosci. Abs
Muchimapura S., Mason R. &
Marsden CA (2003) The effect of isolation rearing on
pre- and postsynaptic serotonergic function in the
rat dorsal hippocampus. Synapse 47: 209-217.
Lapiz MD, Fulford A, Muchimapura S, Mason
R, Parker T, Marsden CA (2003) Influence of postweaning
social isolation in the rat on brain development, conditioned behaviour, and
neurotransmission. Neurosci Behav Physiol.
33:13-29.
Muchimapura S, Fulford AJ, Mason R,
Neuronal ensemble
processing of somatosensory/nociceptive information at multiple spinal &
CNS sites and their modulation by analgesics
with Prof Vicky Chapman
Jhaveri MD, Elmes SJR,
Richardson D, Barrett DA, Kendall DA, Mason R, Chapman v (2008)
Evidence for a novel functional role of cannabinoid CB2 receptors in
the thalamus of neuropathic rats. Eur. J Neuroscience 27:
1722-1730 pdf
Abdul Aziz CB,
Finn D, Mason R & Chapman V (2005) Comparison of
responses of VPL and Po thalamic neurones in naive rats and rats with hindpaw
inflammation: mu‑opioid receptor mediated
inhibitions. Neuropharmacology
48: 607-616. pdf
Abdul Aziz CB, Chapman V, Mason R (2003)
Inhibitory effects of morphine on mechanical punctate
evoked responses of posterior thalamic neurones in the anaesthetised rat. Brit J Pharmacol. 138:
216P
Abdul Aziz CB, Chapman V, Mason R (2003)
Inhibitory effects of morphine on evoked responses of ventral posterolateral neurones in spinal nerve ligated
rats. Brit J Pharmacol.
with Dr M O’Donoghue QMC Nottingham; B Coomber; C Spicer; Prof S Coombes; Dr Markus
Owen
Mason R & Cheer JF (2009) Cannabinoid
receptor activation reverses kainate-induced synchronised burst firing in rat
hippocampus. Frontiers in Integrative
Neuroscience 3: 1-6; e-paper pdf
Coomber B, O’Donoghue MF
& Mason R (2008) Inhibition of endocannabinoid metabolism attenuates
enhanced hippocampal neuronal activity induced by kainic acid.
Synapse 62: 746-755 pdf
Coomber
B, Owen M, O’Donoghue M, & Mason R (2007) The effects of the FAAH inhibitor URB597 on kainate-evoked neuronal ensemble
activity in the rat medial prefrontal cortex.
Coomber, B, O’Donoghue M,
& Mason R (2006) Proceedings Brit J Pharmacol. www.pA2online.org
Mason
R, Owen M, O’Donoghue & Coomber B (2006) Kainate-induced epileptiform neuronal ensemble dynamics between
medial prefrontal cortex and hippocampus in the rat.
Coomber
B, Spicer CH, O'Donoghue M, Mason R (2005) The effects of cannabidiol
in a kainate model of temporal lobe epilepsy. Soc Neurosci Abstracts
Roe C & Mason R (2005)
Effects of the cannabinoid (CB) agonist HU210 on kainite-induced epileptiform
activity in the rat hippocampus using multi-channel extracellular recording Brit J Pharmacol.
Jagger L, S.C.Cheetham,
D.J. Heal & R. Mason
R (2005) Validation of an in vitro model of status epilepticus Brit J Pharmacol.
Jagger E,
Parker, TL Starkey S & Mason R (2002) Kanic
acid-induced epileptiform activity and cell death in hippocampal organotypic
cultures. Brit J Pharmacol. 135:
103P
Jagger E,
Parker L, Hope DT & Mason R (2001) Effect of magnesium ions on bicuculline-induced epileptiform activity in hippocampal
organotypic slices and monolayer hippocampal neuronal networks Brit J Pharmacol. 134:126P.
Sokal DM, Mason R, Parker KG & Parker TL
(2000) Multi-neuronal recordings from rat hippocampal neuronal networks
reveal a differential effect of thapsigargin on bicuculline-induced and GABAzine-induced
epileptiform excitability. Neuropharmacology 39: 2408-2417. pdf
Rodent Ultrasound Vocalisations: Behavioural and
Electrophysiological Studies
with the late Dr
Simon Beckett
Tunstall B,
Beckett SRG & Mason R (2009) Ultrasonic vocalisations explain unexpected
effects on pre-pulse inhibition responses in rats chronically pre-treated with
phencyclidine (PCP). Behav. Brain Res. 202: 184-191. pdf
Tunstal B, Love A, Williams M, Beckett SRG & Mason R (2005) Ultrasonic vocalisations (USVs) in rats: Using Principle Component
Analysis (PCA) to sort the pips from the squeaks. Soc. Neurosci. Abs pdf
Poster
Tunstall B, Gavens E, Coombes S, Beckett SR
and Mason R (2005) Ultrasonic vocalisations in rats:
How shocking is the conditioned avoidance response (CAR) paradigm? British Neurosci
Assoc Abs 8: P5. pdf Poster
Tunstall B, Beckett SRG, Shackleton
T, Mason R (2004) Rat Ultrasonic Vocalisations: Sorting the pips from the
squeaks. British Association of
Psychopharmacology MC32, Harrogate
Tunstall B,
Mason R, Beckett SRG & Shakleton T (2004) Rat language: Characterisation of novel ultrasound
vocalisations (USVs) and juxta-USVs detected in
rats.
Previous
Research Studies
Hypothalamic network control of (i) circadian function (ii)
appetite: Signalling cross-talk between neurotransmitters & neuropeptides
with Dr S Cheetham; Dr H
Piggins & Prof B Rusak
Dempsie Y,
Cheetham S, Wikberg J, Mason R (2002) Effect of neuropeptide Y receptor antagonists BIB03304 and CGP71683A
on neuropeptide Y-evoked responses in the rat lateral
hypothalamic nucleus. Brit
J Pharmacol. 137: 110P
Cutler DJ, Mundey M & Mason R (1999)
Electrophysiological effects of opioid receptor activation on Syrian hamster
suprachiasmatic neurones in vitro. Brain Res Bull. 50 119-125.
Cutler, DJ, Piggins, HD, Selbie
LA & Mason R (1998) Responses to neuropeptide Y
in adult hamster suprachiasmatic nucleus neurones in
vitro. Europ J Pharmacol. 345 155-162.
Roschier U, Heal R, Mason
R, Parker TL & Gross GW. (2003) The
effect of gap junction blockers on the spontaneous network activity of mouse
frontal cortex and spinal cord cultures. Soc.
Neurosci. Abs
Sokal DM, Mason R, Parker KG & Parker TL
(2000) Multi-neuronal recordings from rat hippocampal neuronal networks reveal
a differential effect of thapsigargin on bicuculline-induced and GABAzine-induced
epileptiform excitability. Neuropharmacology: 39: 2408-2417. pdf
Neurobiological studies of drugs of abuse, drug
dependence and mode of action of potential "anti-abuse" agents
with Clare Spicer (ex
Roe); Profs DA Kendall;
Dr VG Wilson
Mason R & Cheer JF (2009) Cannabinoid
receptor activation reverses kainate-induced synchronised burst firing in rat
hippocampus. Frontiers in Integrative
Neuroscience 3: 1-6; e-paper pdf
Cheer JF, et al .
(2003) Lack of response suppression follows repeated ventral tegmental cannabinoid
administration: an in vitro electrophysiological study - Neuropharmacology 44: 633-641
Roe C & Mason R (2002) Effects of
cannabinoid (CB) agonists on rat
hippocampal neuronal firing rate activity using multi-channel extracellular
recording. Brit J Pharmacol. 137:
109P
Cheer JF, et al .
(2000) Lack of response suppression follows repeated ventral tegmental
cannabinoid administration: an in vitro electrophysiological study - Neuroscience 99(4): 661-667
Mundey MK, Blaylock NA Mason R, Glick SD, Maisonneuve,
IM & Wilson VG (2000) Pharmacological comparison of the effect of ibogaine
and 18-methoxycoronaridine on smooth muscle from rat and guinea-pig. Brit.
J. Pharmacol. 129 1561-1568.
Mind-control
robotics EEG mediated control of external devices in
human subjects