Arthritis Research UK Pain Centre
   
   
     
  

Vacancies in Arthritis Pain Research

Vacancies

PhD Studentships

PhD Studentship: determining the role of neuromuscular decline in ageing and disease related musculoskeletal decline

This project will utilise intramuscular electromyography (iEMG) and D2O-proteomics to investigate MU remodelling and to quantify associated neuromuscular markers in order to determine the role of neuromuscular decline in ageing and disease related musculoskeletal decline.  The prospective student would be trained in the latest iEMG and D20-proteomics techniques, alongside further measures of neuromuscular health.

Nottingham is a centre of excellence for Musculoskeletal Theme with NIHR Biomedical Research Centre (BRC) status. This studentship will be based in the BRC and the student will join a vibrant, multidisciplinary team focused on furthering our understanding of knee pain and muscle function. The student will also work with staff from both the Divisions of Rheumatology Orthopaedics and Dermatology and Physiology, Pharmacology and Neuroscience. Both Divisions are well regarded internationally, produce highly cited work, and encourage continuing professional development and collaborative effort. Closing date NOW 16 February 2018. Full details and how to apply

PhD Research Studentship - Lipidomic analysis of biological samples: identification of bioactive lipids associated with osteoarthritic pain 

Description: Osteoarthritis (OA) is a major clinical problem, and chronic pain is one of the dominant presenting symptoms. There are major gaps in our understanding of the mechanisms of OA pain. LC-MS/MS is a highly sensitive method for the analysis of biological samples, which we have used to quantify levels of bioactive lipids in plasma samples from OA sufferers. The aim of this studentship is to build upon this work to identify, and quantify, levels of bioactive lipids in plasma samples from OA sufferers and to perform statistical and pathway analysis with existing clinical data from these subjects (including pain scores). Some additional cell biology methods will be used to address specific hypotheses leading from the studies associated with osteoarthritic pain. Closing date 31 January 2018Further details and how to apply

PhD Research Studentship - MRI techniques

This studentship aims to develop and apply advanced MRI techniques to understand the structural and functional changes of joints underlying chronic osteoarthritis (OA) pain. The poor correlation of standard MRI features of OA with pain outcomes calls for the development of innovative imaging approaches. The study will make use of latest MRI technology (Upright MR scanner) to probe the effects of weight bearing on normal and affected joints using tissue segmentation and shape analysis to improve prediction and understanding of pain. In addition, novel MRI contrasts developed and validated at ultrahigh-field MRI to index key pathological tissue changes will be translated to clinical field strength. Closing date 31 January 2018. Further details and how to apply

Research fellowships

As a research-led institution, The University of Nottingham recognises the value and contribution of early career researchers in delivering its ambitious, high-quality research strategy.

The Arthritis Research UK Pain Centre at The University of Nottingham investigates the mechanisms that lead to the chronic pain experienced by sufferers of arthritis, in order to improve the treatment of that pain.

Our mission is to pursue international excellence in multidisciplinary, translational research, thereby enhancing understanding of arthritis pain and improving its treatment.

The Pain Centre are seeking applicants who are thinking about applying for a fellowship and who would like it to be hosted by the Pain Centre.

Information on internally and externally funded fellowships can be found here

Please send enquiries to paincentre@nottingham.ac.uk

Arthritis Research UK Pain Centre Research pages

 

Arthritis Research UK Pain Centre

Clinical Sciences Building
City Hospital
Nottingham, NG5 1PB

telephone: +44 (0) 115 823 1766 ext 31766
fax: +44 (0) 115 823 1757
email: paincentre@nottingham.ac.uk