High throughput materials discovery
Acknowledgements
Funding from the Wellcome Trust is kindly acknowledged (grant number 085245/Z/08/Z). Nottingham Nanotechnology and Nanoscience Centre is kindly acknowledged for giving access to the Raman system and for the East Midlands Development Agency for funding this equipment.
LBSA Publications in this area
1. Saha, K.; Mei, Y.; Reisterer, C. M.; Pyzocha, N.; Yang, J.; Muffat, J.; Mitalipova, M.; Davies, M. C.; Alexander, M. R.; Langer, R.; Anderson, D. G.; Jaenisch, R., Surface engineered substrates for improved human pluripotent stem cell culture under fully defined conditions. Proc. Natl. Acad. Sci. USA 2011, 108, (46), 18714-18719.
2. Hook, A. L.; Yang, J.; Chen, X.; Roberts, C. J.; Mei, Y.; Anderson, D. G.; Langer, R.; Alexander, M. R.; Davies, M. C., Polymers with hydro-responsive topography identified using high throughput AFM of an acrylate microarray. Soft Matter 2011, 7, (16), 7194-7197.
3. Yang, J.; Mei, Y.; Hook, A. L.; Taylor, M.; Urquhart, A. J.; Bogatyrev, S. R.; Langer, R.; Anderson, D. G.; Davies, M. C.; Alexander, M. R., Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays. Biomaterials 2010, 31, (24), 8827-8838.
4. Mei, Y.; Saha, K.; Bogatyrev, S. R.; Yang, J.; Hook, A. L.; Kalcioglu, I.; Cho, S.-W.; Mitalipova, M.; Pyzocha, N.; Rojas, F.; Vliet, K. J. V.; Davies, M. C.; Alexander, M. R.; Langer, R.; Jaenisch, R.; Anderson, D. G., Combinatorial Development of Biomaterials for Clonal Growth of Human Pluripotent Stem Cells. Nature Materials 2010, 9, 768-778.
5. Hook, A. L.; Anderson, D.; Langer, R.; Williams, P.; Davies, M. C.; Alexander, M. R., High throughput methods applied in biomaterial development and discovery. Biomaterials 2010, 31, (2), 187-198.
6. Davies, M. C.; Alexander, M. R.; Hook, A. L.; Yang, J.; Mei, Y.; Taylor, M.; Urquhart, A. J.; Langer, R.; Anderson, D. G., High Throughput Surface Characterisation – a review of a new tool for screening prospective biomedical material arrays Journal of Drug Targeting 2010, 18, (10), 741-751.
7. Taylor, M.; Urquhart, A. J.; Anderson, D. G.; Langer, R.; Davies, M. C.; Alexander, M. R., Partial Least Squares Regression as a Powerful Tool for Investigating Large Combinatorial Polymer Libraries. Surface and Interface Analysis: MVA Special Issue 2009, 41, (2), 127-135.
8. Mei, Y.; Gerecht, S.; Taylor, M.; Urquhart, A. J.; Bogatyrev, S. R.; Cho, S.-W.; Davies, M. C.; Alexander, M. R.; Langer, R. S.; Anderson, D. G., Mapping the Interactions among Biomaterials, Adsorbed Proteins and Human Embryonic Stem Cells. Advanced Materials 2009, 21, 1-6.
9. Urquhart, A.; Taylor, M.; Anderson, D.; Langer, R.; Davies, M.; Alexander, M., TOF-SIMS Analysis Of A 576 Micro-Patterned Co-Polymer Array Reveals Surface Moieties That Control Wettability. Analytical Chemistry 2008, 80, 135-142.
10. Taylor, M.; Urquhart, A. J.; Anderson, D. G.; Williams, P. M.; Langer, R.; Alexander, M. R.; Davies, M. C., A Methodology for Investigating Protein Adhesion and Adsorption to Microarrayed Combinatorial Polymers. Macromolecular Rapid Communications 2008, 15, (29), 1298-1302.
11. Urquhart, A.; Taylor, M.; Anderson, D.; Langer, R.; Alexander, M.; Davies, M. C., High through-put surface characterisation of arrayed biomaterials. Advanced Materials 2007, 19, 2486–2491.
12. Taylor, M.; Urquhart, A. J.; Zelzer, M.; Davies, M. C.; Alexander, M. R., Picolitre water contact angle measurement on polymers. Langmuir Letters 2007, 23, (13), 6875-6878.