Recent Publications
The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex.
Doidge R, Mittal S, Aslam A, Winkler GS.
PLoS One. 2012;7(12):e51331. doi: 10.1371/journal.pone.0051331. Epub 2012 Dec 7.
PMID: 23236473 [PubMed - in process]
Inhibition of polyadenylation reduces inflammatory gene induction.
Kondrashov A, Meijer HA, Barthet-Barateig A, Parker HN, Khurshid A, Tessier S, Sicard M, Knox AJ, Pang L, De Moor CH.
RNA. 2012 Dec;18(12):2236-50. doi: 10.1261/rna.032391.112. Epub 2012 Nov 1.
PMID: 23118416 [PubMed - in process] Free PMC Article
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Liver-specific microRNA-122: Biogenesis and function.
Jopling C.
RNA Biol. 2012 Feb;9(2):137-42. doi: 10.4161/rna.18827. Epub 2012 Feb 1. Review.
PMID: 22258222 [PubMed - indexed for MEDLINE] Free PMC Article
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Deadenylation of cytoplasmic mRNA by the mammalian Ccr4-Not complex.
Doidge R, Mittal S, Aslam A, Winkler GS.
Biochem Soc Trans. 2012 Aug;40(4):896-901. doi: 10.1042/BST20120074. Review.
PMID: 22817755 [PubMed - indexed for MEDLINE]
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The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.
Mittal S, Aslam A, Doidge R, Medica R, Winkler GS.
Mol Biol Cell. 2011 Mar 15;22(6):748-58. doi: 10.1091/mbc.E10-11-0898. Epub 2011 Jan 13.
PMID: 21233283 [PubMed - indexed for MEDLINE] Free PMC Article
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Sequence determinants for the tandem recognition of UGU and CUG rich RNA elements by the two N--terminal RRMs of CELF1.
Edwards J, Malaurie E, Kondrashov A, Long J, de Moor CH, Searle MS, Emsley J.
Nucleic Acids Res. 2011 Oct;39(19):8638-50. doi: 10.1093/nar/gkr510. Epub 2011 Jul 9.
PMID: 21743084 [PubMed - indexed for MEDLINE]
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