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Division of
Molecular and Cellular Science
   
   
  

The Division of Molecular and Cellular Sciences (MCS) undertakes pioneering research in the basic and biomedical sciences, aimed at understanding biological processes, and applied research in the areas of target identification, bioassay development and drug discovery, bioanalysis and translational research. Biological processes are investigated at the molecular and cellular levels, incorporating molecular biology, cell biology, immunology and systems biology.

MCS houses four areas of research; please click on each group for more information or academic member for a more detailed review of their work.

 

 

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Latest News

David Pritchard's work featured on front cover of Clinical and Experimental Allergy

Description
Professor David Pritchard's work in the Immune Modulation Research Group is featured on the front cover of Clinical & Experimental Allergy, April 2012.
Date:
16/05/2012

Next generation medicine and the pharmaceutical pioneers

Description
Next generation medicine - doctoral training
Date:
02/04/2012

Recent Publications

 

Mittal S, Aslam A, Brierley R, Medica R, Winkler GS. (2011) The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence. Mol Biol Cell. In press

 

Bottley A, Phillips NM, Webb TE, Willis AE, Spriggs KA. (2010) eIF4A inhibition allows translational regulation of mRNAs encoding proteins involved in Alzheimer's disease. PLoS One 5(9). pii: e13030.

 

WADELIN F, FULTON J, MCEWAN PA, SPRIGGS KA, EMSLEY J & HEERY DM. (2010) Leucine-Rich Repeat Protein PRAME: Expression, Potential Functions and Clinical Implications for Leukaemia. Mol Cancer 2010 Aug 27;9:226

 

JAMES V, ZHANG Y, FOXLER DE, DE MOOR CH, KONG YW, WEBB TM, SELF TJ, FENG Y, LAGOS D, CHU CY, RANA TM, MORLEY SJ, LONGMORE GD, BUSHELL M, SHARP TV. (2010) LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing. Proc Natl Acad Sci USA. 107:12499-504. 107:12499-504.

 

CANNELL IG, KONG YW, JOHNSTON SJ, CHEN ML, COLLINS HM, DOBBYN HC, ELIA A, KRESS TR, DICKENS M, CLEMENS MJ, HEERY DM, GAESTEL M, EILERS M, WILLIS AE, BUSHELL M. (2010) p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication. Proc Natl Acad Sci USA. 107:5375-80. . 107:5375-80.

 

 

School of Pharmacy

University of Nottingham
University Park
Nottingham, NG7 2RD

telephone: +44 (0) 115 951 5100
fax: +44 (0) 115 951 5102
email: pharmacy-enquiries@nottingham.ac.uk