Associate Professor, Faculty of Science
I received my training as a chemist at the University of Graz. As a Masters student at the University Louis Pasteur, Strasbourg, I studied the folding and structure of synthetic peptides. This work sparked my interest and fascination for protein structure from which I pursued a Ph.D. in protein crystallography under the supervision of Christoph Kratky, working on the structure and mechanism of an unusual flavoprotein that has wide-ranging applications in industrial biocatalysis.
During my postdoctoral years at Imperial College London in the laboratory of Paul Freemont and Xiaodong Zhang I uncovered how the multi-functional molecular machine, the AAA ATPase p97, that has been associated with neurodegenerative diseases and cancer, recognizes adaptor proteins. After a brief period as research fellow in the School of Pharmacy, University of Nottingham, I was appointed lecturer in protein crystallography.
I am interested in how macromolecular structure determines function and can help explain cellular events. My main area of expertise is macromolecular X-ray crystallography, which I combine with other… read more
I am interested in how macromolecular structure determines function and can help explain cellular events. My main area of expertise is macromolecular X-ray crystallography, which I combine with other biophysical and biochemical techniques. My research is aimed at:
Current research topics include:
For further details please visit the Structural Biology group website.
Memberships of Committees & Professional Bodies
Biochemical Society; British Crystallographic Association
The University of Nottingham University Park Nottingham, NR7 2RD
telephone: +44 (0)115 846 8001 email:cbsresearchersforum@nottingham.ac.uk