Centre for Evidence Based Hand Surgery
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Complex regional pain syndrome & neuropathic pain

 

Epidemiology

The incidence of complex regional pain syndrome in simultaneous surgical treatment of carpal tunnel syndrome and Dupuytren contracture.
Buller M, Schulz S, Kasdan M, Wilhelmi BJ.
Hand (N Y). 2017 Jul 1:1558944717718345. doi: 10.1177/1558944717718345. [Epub ahead of print]

Comparison of effects of seven treatment methods for distal radius fracture on minimizing complex regional pain syndrome.
Wang JH, Sun T.
Arch Med Sci. 2017 Feb 1;13(1):163-173. doi: 10.5114/aoms.2016.59794.

What outcome measures are commonly used for complex regional pain syndrome clinical trials? A systematic review of the literature.
Grieve S, Jones L, Walsh N, McCabe C.
Eur J Pain. 2016 Mar;20(3):331-40. doi: 10.1002/ejp.733. Epub 2015 Jun 15.

Potential risk factors for the onset of complex regional pain syndrome type 1: a systematic literature review.
Pons T, Shipton EA, Williman J, Mulder RT.
Anesthesiol Res Pract. 2015;2015:956539. doi: 10.1155/2015/956539. Epub 2015 Jan 26.

Placebo responses in long-standing complex regional pain syndrome: a systematic review and meta-analysis.
Mbizvo GK, Nolan SJ, Nurmikko TJ, Goebel A.
J Pain. 2015 Feb;16(2):99-115. doi: 10.1016/j.jpain.2014.11.008. Epub 2014 Dec 3.

Complications following volar locking plate fixation for distal radial fractures: a systematic review.
Bentohami A, de Burlet K, de Korte N, van den Bekerom MP, Goslings JC, Schep NW.
J Hand Surg Eur Vol. 2014 Sep;39(7):745-54. doi: 10.1177/1753193413511936. Epub 2013 Nov 21.

The outcome of complex regional pain syndrome type 1: a systematic review.
Bean DJ, Johnson MH, Kydd RR.
J Pain. 2014 Jul;15(7):677-90. doi: 10.1016/j.jpain.2014.01.500. Epub 2014 Feb 12.

A review of psychosocial factors in complex regional pain syndrome.
Lohnberg JA, Altmaier EM.
J Clin Psychol Med Settings. 2013 Jun;20(2):247-54. doi: 10.1007/s10880-012-9322-3.

Prognostic factors in complex regional pain syndrome 1: a systematic review.
Wertli M, Bachmann LM, Weiner SS, Brunner F.
J Rehabil Med. 2013 Mar;45(3):225-31. doi: 10.2340/16501977-1103.

A systematic review of psychometric evaluations of outcome assessments for complex regional pain syndrome.
Packham T, MacDermid JC, Henry J, Bain J.
Disabil Rehabil. 2012;34(13):1059-69. doi: 10.3109/09638288.2011.626835. Epub 2011 Dec 9.

Peripheral trauma and movement disorders: a systematic review of reported cases.
van Rooijen DE, Geraedts EJ, Marinus J, Jankovic J, van Hilten JJ.
J Neurol Neurosurg Psychiatry. 2011 Aug;82(8):892-8. doi: 10.1136/jnnp.2010.232504. Epub 2011 Apr 14.

 
Diagnosis

Usefulness of bone scintigraphy for the diagnosis of Complex Regional Pain Syndrome 1: A systematic review and Bayesian meta-analysis.
Wertli MM, Brunner F, Steurer J, Held U.
PLoS One. 2017 Mar 16;12(3):e0173688. doi: 10.1371/journal.pone.0173688. eCollection 2017 Mar 16.

Cappello ZJ, Kasdan ML, Louis DS.
J Hand Surg Am. 2012 Feb;37(2):288-96. doi: 10.1016/j.jhsa.2011.10.035. Epub 2011 Dec 15.
 
Prevention

Efficacy of vitamin C in preventing complex regional pain syndrome after wrist fracture: A systematic review and meta-analysis.
Aim F, Klouche S, Frison A, Bauer T, Hardy P.
Orthop Traumatol Surg Res. 2017 Mar 5. pii: S1877-0568(17)30055-5. doi: 10.1016/j.otsr.2016.12.021. [Epub ahead of print]

Comparison of effects of seven treatment methods for distal radius fracture on minimizing complex regional pain syndrome.
Wang JH, Sun T.
Arch Med Sci. 2017 Feb 1;13(1):163-173. doi: 10.5114/aoms.2016.59794.

Effect of perioperative vitamin C supplementation on postoperative pain and the incidence of chronic regional pain syndrome: A systematic review and meta-analysis.
Chen S, Roffey DM, Dion CA, Arab A, Wai EK.
Clin J Pain. 2016 Feb;32(2):179-85. doi: 10.1097/AJP.0000000000000218.

Vitamin C to prevent complex regional pain syndrome in patients with distal radius fractures: a meta-analysis of randomized controlled trials.
Evaniew N, McCarthy C, Kleinlugtenbelt YV, Ghert M, Bhandari M.
J Orthop Trauma. 2015 Aug;29(8):e235-41. doi: 10.1097/BOT.0000000000000305.

Role of vitamin C in prevention of complex regional pain syndrome after distal radius fractures: a meta-analysis.
Meena S, Sharma P, Gangary SK, Chowdhury B.
Eur J Orthop Surg Traumatol. 2015 May;25(4):637-41. doi: 10.1007/s00590-014-1573-2. Epub 2014 Dec 9.

Testing the validity of preventing chronic regional pain syndrome with vitamin C after distal radius fracture. [Corrected].
Malay S, Chung KC.
J Hand Surg Am. 2014 Nov;39(11):2251-7. doi: 10.1016/j.jhsa.2014.08.009. Epub 2014 Sep 16.
Erratum in: J Hand Surg Am. 2014 Dec;39(12):2551.

Efficacy and safety of high-dose vitamin C on complex regional pain syndrome in extremity trauma and surgery--systematic review and meta-analysis.
Shibuya N, Humphers JM, Agarwal MR, Jupiter DC.
J Foot Ankle Surg. 2013 Jan-Feb;52(1):62-6. doi: 10.1053/j.jfas.2012.08.003. Epub 2012 Sep 15.

 
Treatment

Fentanyl for neuropathic pain in adults.
Derry S, Stannard C, Cole P, Wiffen PJ, Knaggs R, Aldington D, Moore RA.
Cochrane Database Syst Rev. 2016 Oct 11;10:CD011605

Local anaesthetic sympathetic blockade for complex regional pain syndrome.
O'Connell NE, Wand BM, Gibson W, Carr DB, Birklein F, Stanton TR.
Cochrane Database Syst Rev. 2016 Jul 28;7:CD004598. doi: 10.1002/14651858.CD004598.pub4.

Physiotherapy for pain and disability in adults with complex regional pain syndrome (CRPS) types I and II.
Smart KM, Wand BM, O'Connell NE.
Cochrane Database Syst Rev. 2016 Feb 24;2:CD010853. doi: 10.1002/14651858.CD010853.pub2.

Cervico-thoracic or lumbar sympathectomy for neuropathic pain and complex regional pain syndrome.
Straube S, Derry S, Moore RA, Cole P.
Cochrane Database Syst Rev. 2013 Sep 2;(9):CD002918. doi: 10.1002/14651858.CD002918.pub3.

Interventions for treating pain and disability in adults with complex regional pain syndrome.
O'Connell NE, Wand BM, McAuley J, Marston L, Moseley GL.
Cochrane Database Syst Rev. 2013 Apr 30;(4):CD009416. doi: 10.1002/14651858.CD009416.pub2.

Bisphosphonates for treatment of complex regional pain syndrome type 1: a systematic literature review and meta-analysis of randomized controlled trials versus placebo.
Chevreau M, Romand X, Gaudin P, Juvin R, Baillet A.
Joint Bone Spine. 2017 Apr 10. pii: S1297-319X(17)30072-6. doi: 10.1016/j.jbspin.2017.03.009. [Epub ahead of print]

Update on the effects of graded motor imagery and mirror therapy on complex regional pain syndrome type 1: A systematic review.
Méndez-Rebolledo G, Gatica-Rojas V, Torres-Cueco R, Albornoz-Verdugo M, Guzmán-Muñoz E.
J Back Musculoskelet Rehabil. 2016 Nov 11. [Epub ahead of print]

A comprehensive outcome-specific review of the use of spinal cord stimulation for complex regional pain syndrome.
Visnjevac O, Costandi S, Patel BA, Azer G, Agarwal P, Bolash R, Mekhail NA.
Pain Pract. 2016 Oct 14. doi: 10.1111/papr.12513. [Epub ahead of print]

EAN guidelines on central neurostimulation therapy in chronic pain conditions.
Cruccu G, Garcia-Larrea L, Hansson P, Keindl M, Lefaucheur JP, Paulus W, Taylor R, Tronnier V, Truini A, Attal N.
Eur J Neurol. 2016 Oct;23(10):1489-99. doi: 10.1111/ene.13103. Epub 2016 Aug 11.

Intravenous therapies for complex regional pain syndrome: a systematic review.
Xu J, Yang J, Lin P, Rosenquist E, Cheng J.
Anesth Analg. 2016 Mar;122(3):843-56. doi: 10.1213/ANE.0000000000000999.

The efficacy of movement representation techniques for treatment of limb pain--a systematic review and meta-analysis.
Thieme H, Morkisch N, Rietz C, Dohle C, Borgetto B.
J Pain. 2016 Feb;17(2):167-80. doi: 10.1016/j.jpain.2015.10.015. Epub 2015 Nov 6.

Motor imagery and its effect on complex regional pain syndrome: an integrative review.
de Souza NS, Martins AC, Bastos VH, Orsini M, Leite MA, Teixeira S, Velasques B, Ribeiro P, Bittencourt J, Matta AP, Filho PM.
Neurol Int. 2015 Dec 31;7(3):5962. doi: 10.4081/ni.2015.5962. eCollection 2015 Dec 29.

Utilization of motor imagery in upper limb rehabilitation: a systematic scoping review.
Harris JE, Hebert A.
Clin Rehabil. 2015 Nov;29(11):1092-107. doi: 10.1177/0269215514566248. Epub 2015 Jan 20.

A systematic review of ketamine for complex regional pain syndrome.
Connolly SB, Prager JP, Harden RN.
Pain Med. 2015 May;16(5):943-69. doi: 10.1111/pme.12675. Epub 2015 Jan 13.

Invasive treatments for complex regional pain syndrome in children and adolescents: a scoping review.
Zernikow B, Wager J, Brehmer H, Hirschfeld G, Maier C.
Anesthesiology. 2015 Mar;122(3):699-707. doi: 10.1097/ALN.0000000000000573.

Rational pain management in complex regional pain syndrome 1 (CRPS 1)--a network meta-analysis.
Wertli MM, Kessels AG, Perez RS, Bachmann LM, Brunner F.
Pain Med. 2014 Sep;15(9):1575-89. doi: 10.1111/pme.12466.

Treatment of complex regional pain syndrome in adults: a systematic review of randomized controlled trials published from June 2000 to February 2012.
Cossins L, Okell RW, Cameron H, Simpson B, Poole HM, Goebel A.
Eur J Pain. 2013 Feb;17(2):158-73. doi: 10.1002/j.1532-2149.2012.00217.x. Epub 2012 Oct 5.

Effect of immunomodulating medications in complex regional pain syndrome: a systematic review.
Dirckx M, Stronks DL, Groeneweg G, Huygen FJ.
Clin J Pain. 2012 May;28(4):355-63. doi: 10.1097/AJP.0b013e31822efe30.

Efficacy and safety of ketamine in patients with complex regional pain syndrome: a systematic review.
Azari P, Lindsay DR, Briones D, Clarke C, Buchheit T, Pyati S.
CNS Drugs. 2012 Mar 1;26(3):215-28. doi: 10.2165/11595200-000000000-00000.

Therapy-resistant complex regional pain syndrome type I: to amputate or not?
Bodde MI, Dijkstra PU, den Dunnen WF, Geertzen JH.
J Bone Joint Surg Am. 2011 Oct 5;93(19):1799-805. doi: 10.2106/JBJS.J.01329.

The clinical aspects of mirror therapy in rehabilitation: a systematic review of the literature.
Rothgangel AS, Braun SM, Beurskens AJ, Seitz RJ, Wade DT.
Int J Rehabil Res. 2011 Mar;34(1):1-13. doi: 10.1097/MRR.0b013e3283441e98.

 

 

 

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Centre for Evidence Based Hand Surgery

The University of Nottingham
C Floor, West Block, QMC
Nottingham, NG7 2UH


telephone: +44 (0) 115 823 1115
email:CEBHS@nottingham.ac.uk