Study on colonic behavior in health and IBS to be published in Neurogastroenterology and Motility

Research by Nottingham scientists studying colonic behaviour in health and Irritable Bowel Syndrome to be published in the leading peer-reviewed journal Neurogastroenterology and Motility.

The paper -- “Fasting and post-prandial volumes of the undisturbed colon: normal values and changes in diarrhoea-predominant Irritable Bowel Syndrome measured using serial MRI” provides accurate data on the volumes of the colon in healthy volunteers and patients before and after a meal.

The ascending colon in diarrhoea-predominant Irritable Bowel Syndrome (D-IBS) patients appeared less able to accommodate post-prandial inflow which may account for faster colonic transit.

This new knowledge is important as one tries to apply physiological principles to try to improve understanding of colonic behavior in health and IBS.

Find out more about gastrointestinal MRI research at the University of Nottingham.