People with knee injury four times more likely to develop knee osteoarthritis

People with knee injury are four times more likely to develop knee osteoarthritis (OA) than those without knee injury, according to a study led by Dr Weiya Zhang, Associate Professor and Reader at the Division of Academic Rheumatology, published in the leading specialist journal Osteoarthritis and Cartilage.

The paper, ‘History of knee injuries and knee osteoarthritis: a meta-analysis of observational studies’, is part of a research programme to develop global risk prediction and reduction models for knee OA which has earlier identified three major risk factors—obesity, occupational risk and knee injury.

Findings relating to the relative contributions of the other two risk factors to the development of knee OA have also been published in Arthritis Research & Care (http://dx.doi.org/10.1002/acr.20464) and in Osteoarthritis and Cartilage
(http://www.oarsijournal.com/article/S1063-4584(11)00067-7/abstract).