Matthew Hurley

Contact

• workRoom Academic Department of Child Health E Floor East Block Queens Medical Centre
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work0115 82 30623
• fax0115 82 30626
• matthew.hurley@nottingham.ac.uk

Teaching Summary

Dr Hurley teaches medical students as part of their 4th year paediatrics placement. He also supervises and examines medical students undertaking research projects for the award of BMedSci.

Research Summary

Dr Hurley is supported by the Wellcome Trust to undertake research focusing upon lung infection in children with cystic fibrosis. He is undertaking laboratory studies investigating ways in which… read more

Selected Publications

• HURLEY, M N, PRAYLE, A P and SMYTH, A R, 2012. Delayed publication of clinical trials in cystic fibrosis. Journal of Cystic Fibrosis. 11(1), 14-17
• PRAYLE AP, HURLEY MN and SMYTH AR, 2012. Compliance With Mandatory Reporting Of Clinical Trial Results On Clinicaltrials.Gov: Cross Sectional Study. British Medical Journal. 344, d7373
• KADAM, RU, BERGMANN, M, HURLEY, M, GARG, D, CACCIARINI, M, SWIDERSKA, MA, NATIVI, C, SATTLER, M, SMYTH, AR, WILLIAMS, P, CAMARA, M, STOCKER, A, DARBRE, T and REYMOND, JL, 2011. A Glycopeptide Dendrimer Inhibitor Of The Galactose-Specific Lectin Leca And Of Pseudomonas Aeruginosa Biofilms Angewandte Chemie-International Edition. 50(45), 10631-10635
• HURLEY MN, PRAYLE AP and FLUME P, 2012. Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (Protocol) Cochrane Database of Systematic Reviews. Art. No.: CD009730

• View all publications

Current Research

Dr Hurley is supported by the Wellcome Trust to undertake research focusing upon lung infection in children with cystic fibrosis. He is undertaking laboratory studies investigating ways in which these difficult infections may be overcome. This includes investigating ways in which it may be possible to increase the susceptibility of bacteria to antibiotics to which they may have become resistant. This work has relevance not only to those with CF, but also others who have infections with antibiotic resistant bacteria.

Dr Hurley has previously undertaken systematic reviews with the Cochrane Collaboration and so is interested in examining the publication of clinical studies and use of evidence of clinical trials. He is also interested in the dissemination of clinical trial results to wider audiences and public engagement in science.

• HURLEY, M N, PRAYLE, A P and SMYTH, A R, 2012. Delayed publication of clinical trials in cystic fibrosis. Journal of Cystic Fibrosis. 11(1), 14-17
• PRAYLE AP, HURLEY MN and SMYTH AR, 2012. Compliance With Mandatory Reporting Of Clinical Trial Results On Clinicaltrials.Gov: Cross Sectional Study. British Medical Journal. 344, d7373
• HURLEY MN, PRAYLE AP and FLUME P, 2012. Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis (Protocol) Cochrane Database of Systematic Reviews. Art. No.: CD009730
• HURLEY MN, ARIFF AHA, BERTENSHAW C, BHATT J and SMYTH AR, 2012. Results of antibiotic susceptibility testing do not influence clinical outcome in children with cystic fibrosis. Journal of cystic fibrosis : official journal of the european cystic fibrosis society. (In Press.)
• HURLEY, M., BHATT, J. and SMYTH, A., 2011. Treatment massive haemoptysis in cystic fibrosis with tranexamic acid JOURNAL- ROYAL SOCIETY OF MEDICINE -SUPPLEMENT-. VOL 104(SUPP/1), 49-52
• HURLEY, M. N. and SMYTH, A. R., 2011. Optimizing respiratory health in children with cystic fibrosis PAEDIATRICS AND CHILD HEALTH -ELSEVIER-. VOL 21(NUMBER 5), 201-206
• KADAM, RU, BERGMANN, M, HURLEY, M, GARG, D, CACCIARINI, M, SWIDERSKA, MA, NATIVI, C, SATTLER, M, SMYTH, AR, WILLIAMS, P, CAMARA, M, STOCKER, A, DARBRE, T and REYMOND, JL, 2011. A Glycopeptide Dendrimer Inhibitor Of The Galactose-Specific Lectin Leca And Of Pseudomonas Aeruginosa Biofilms Angewandte Chemie-International Edition. 50(45), 10631-10635
• LOW, D, HURLEY, M, PRAYLE, A and SMYTH, A, 2011. A UK REGISTRY STUDY OF PROPHYLACTIC ANTIBIOTIC USE FOR STAPHYLOCOCCUS AUREUS IN CHILDREN WITH CYSTIC FIBROSIS Thorax. 66(S4), A163
• PRAYLE, ANDREW P, HURLEY, MATTHEW N and SMYTH, ALAN R, 2010. Percutaneous lines for delivering intravenous antibiotics in people with cystic fibrosis. Cochrane database of systematic reviews (Online). 11, CD008243
• HURLEY, MATTHEW N, FORRESTER, DOUGLAS L and SMYTH, ALAN R, 2010. Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis. Cochrane database of systematic reviews (Online). 10, CD008037
• SMYTH AR, HURLEY MN., 2010. TARGETING THE PSEUDOMONAS AERUGINOSA BIOFILM TO COMBAT INFECTIONS IN PATIENTS WITH CYSTIC FIBROSIS. Drugs of the Future. 35, 1007-1014
• HURLEY, M, DINEEN, R, PADFIELD, C J H, WILSON, S, STEPHENSON, T, VYAS, H, MCCONACHIE, N and JASPAN, T, 2010. Is there a causal relationship between the hypoxia-ischaemia associated with cardiorespiratory arrest and subdural haematomas? An observational study. The British journal of radiology.
• HURLEY, M., CAMARA, M., WILLIAMS, P. and SMYTH, A., 2010. Commercial garlic preparations inhibit quorum sensing lasB and pqsA gene expression in Pseudomonas aeruginosa clinical strains Journal of Cystic Fibrosis. VOL 9(SUPP/1), S21
• HURLEY, MATTHEW and SMITH, CRAIG, 2007. Patients' blogs--do doctors have anything to fear? BMJ. 335(7621), 645-6