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School of Clinical Sciences
   
   
  

PhD Projects (Self-funded Vacancies)

The projects listed below are available to self-funded Home/EU and/or International Students. 

The fee associated with each fee band can be found at: http://www.nottingham.ac.uk/fees/tuitionfees/201213/postgraduateresearchcourses.aspx#clinical

The projects themselves do not have funding attached to them and so potential students would have to bring their own funding or seek sponsorship. The University offers scholarship opportunities to International students and Home/EU students. Please note that you must be in receipt of an offer to study before you can apply for a Scholarship with the University of Nottingham.

For further information about each project, please contact the respective supervisors directly. Their profiles and contact details can be found by clicking on each name.

To make a formal application, please apply online. It can take up to 6 weeks to process an offer from receipt of application.

Current Opportunities

 
Anaesthesia

Supervisor

Project Title

Theme

Keywords

Fee Band

Ravi P Mahajan Patient participation in preoperative assessment -- for Home & EU students/ International Students Patient Safety; Anaesthesia; Quality outcome; Patient satisfaction  Patient safety; Quality improvement; Pre-anaesthesia assessment Low cost research
Ravi P Mahajan Medication errors – strategies to prevent them -- for Home & EU students/ International Students Patient Safety; Anaesthesia; Quality outcome; Pharmacy Patient safety; medication error; Quality improvement Low cost research
Ravi P Mahajan Development of tools for effective handover -- for Home & EU students/ International Students Patient Safety; Anaesthesia; Critical Care; Quality outcome Patient Safety; Anaesthesia; Critical Care; Quality outcome Low cost research
Ravi P Mahajan Strategies to stabilize haemodynamics during anaesthesia -- for Home & EU students/ International Students Patient safety; Anaesthesia; Quality; Outcome Patient safety; Quality improvement Low cost research
Iain Moppett Factors affecting hepatic injury following surgery in the prone position -- for Home & EU students/ International Students Anaesthesia; surgery; cardiovascular physiology; liver disease Anaesthesia; surgery; cardiovascular physiology; liver disease; clinical High cost lab-based research
Iain Moppett The anaesthetist as vector for infection -- for Home & EU students/ International Students surgical site infection; microbiology; hand hygiene surgical site infection; microbiology; hand hygiene; contamination High cost lab-based research
Iain Moppett Non-invasive prediction of fluid responsiveness in the self-ventilating awake patient -- for Home & EU students/ International Students critical care; anaesthesia; surgery; cardiovascular physiology statistics; physiology; clinical; trials; monitoring High cost lab-based research
Iain Moppett Distractions and interruptions in the operating theatre -- for Home & EU students/International Students surgery; anaesthesia; patient safety psychology; patient safety; anaesthesia; distraction; interruption Low-cost research
Assisted Reproductive Treatment

Supervisor

Project Title

Theme

Keywords

Fee Band

Walid Maalouf The Effects of Pre-Implantation Embryo Biopsy on Further Development of the Offspring -- for Home & EU students/ International Students Mechanical and Thermal (Laser) effects of embryo biopsy on gene expression and development of the future offspring ART; ICSI; PGD; Embryo Biopsy; Molecular Biology Lab-based research
Walid Maalouf/Louise Mullany The Influence of Linguistic Strategies on the Patients’ Experience of Assisted Reproductive Treatment -- for Home & EU students/ International Students Effective communication strategies with patients ART; Linguistics; Language; Fertility; IVF; Reproductive Sciences Low-cost research
Asthma

Supervisor

Project Title

Theme

Keywords

Fee Band

Ian Sayers Functional genetics of recently identified asthma susceptibility genes PDF file icon Functional studies of polymorphic variation linked to asthma susceptibility asthma; genetic susceptibility; functional analyses; primary airway cell models High cost lab-based research
Galina Pavlovskaya Hyperpolarized 83Kr as a novel contrast agent for magnetic resonance imaging (MRI) of lungsPDF file icon Lung imaging magnetic resonance imaging (MRI); hyperpolarized 83Kr; 129Xe; 3He; IPF; ALI; asthma Lab-based research
Breast cancer

Supervisor

Project Title

Theme

Keywords

Fee Band

KL Cheung Clinical & cost effectiveness of therapeutic strategies in older women with early primary breast cancer PDF file icon Breast cancer Breast cancer; Elderly; Clinical effectiveness; Cost effectiveness; Therapeutic strategies Low cost research
KL Cheung  Lymphoedema in women with primary or advanced breast carcinoma PDF file icon Breast cancer Breast cancer; Lymphoedema Low cost research
KL Cheung Biological features of early primary breast cancer in older women and correlation with clinical outcome PDF file icon Breast cancer Breast cancer; Elderly; Tumour biology; Clinical outcome High cost lab-based research
KL Cheung Psychosocial and quality of life issues in older women with early primary breast cancerPDF file icon Breast cancer Breast cancer; Elderly High cost lab-based research
Cancer

Supervisor

Project Title

Theme

Keywords

Fee Band

David Bates Tumour angiogenesis and the control of splicing PDF file icon Cancer Cancer, angiogenesis, VEGF, RNA, splicing High cost lab-based research
David Bates RNA binding proteins that control tumour growth by regulating blood vessel growth PDF file icon Cancer Cancer, angiogenesis, VEGF, RNA, splicing High cost lab-based research
Beth Coyle Functional analysis of ABC transporter mediated drug resistance in paediatric brain tumours PDF file icon Cancer Cancer stem cells; Brain tumours; Drug resistance High cost lab-based research
Abdolrahman Shams Nateri In vitro and in vivo approaches to investigate the regulation of the intestinal stem cell niche in the gastrointestinal tract development and cancer -- full project details is available upon request -- for Home & EU students/ International Students Cancer Genetics and Stem Cell Biology Intestinal stem cells; Cancer stem cells; Loss & gain of gene function; Signalling & Transcription Lab-based in vitro research
Health and Nutrition

Supervisor

Project Title

Theme

Keywords

Fee Band

Michael Symonds/ Helen Budge Environmental regulation of brown adipose tissue function PDF file icon health and well being, imaging obesity, adipose tissue, development, growth Lab-based 
Michael Symonds/ Helen Budge Early life nutrition, metabolic development and health -- for Home & EU students/International Students Health and nutrition through the life cycle Nutrition; reproduction; obesity; child health; endocrinology; development Lab-based research
Infection, Immunity and Inflammation

Supervisor

Project Title

Theme

Keywords

Fee Band

Karen Robinson Regulatory T-cell responses to Helicobacter pylori in health and diseasePDF file icon Immunity to gastro-intestinal infection Helicobacter pylori; regulatory T-cells; immunosuppressive function; protection from disease High cost lab-based research
Y R Mahida Investigation of interactions between host cells and C. difficile toxins --for International Students only currently; when funding has been secured, will also be available to Home & EU students Infection, Immunity and Inflammation colitis; apoptosis; receptors; cell signalling; cytokines Lab-based research
Liver surgery and regeneration

Supervisor

Project Title

Theme

Keywords

Fee Band

Dileep N Lobo, John Hammond, Salvatore Papa Understanding how the liver heals: the pathophysiology of sepsis induced liver failurePDF file icon liver surgery and regeneration liver regeneration; JNK signalling; sepsis Lab-based research
Mathematical Modelling of Biological Systems

Supervisor

Project Title

Theme

Keywords

Fee Band

David Bates The structure of the human glomerulus  PDF file icon Mathematical modelling of biological systems Fluid dynamics, mathematical modelling, electron microscopy Low-cost research
Neuro-imaging

Supervisor

Project Title

Theme

Keywords

Fee Band

Henryk Faas Molecular magnetic resonance imaging of neuroinflammation in the brainPDF file icon Neuro-imaging MRI; neuroinflammation High cost lab-based research
Neuro-Immunlogy

Supervisor

Project Title

Theme

Keywords

Fee Band

Bruno Gran Innate regulation of autoimmune inflammatory demyelination in multiple sclerosis Neuro-Immunology Multiple sclerosis; experimental autoimmune encephalomyelitis; T cells, dendritic cells; T-cell receptors; Toll-like receptors Lab-based research
Newborn Outcomes

Supervisor

Project Title

Theme

Keywords

Fee Band

Don Sharkey Computational modelling of stress associated newborn brain injuryPDF file icon Newborn outcomes premature; newborn; brain injury; modelling Lab-based research
Don Sharkey Development of a neonatal nutrition tool to improve long-term outcomesPDF file icon Newborn outcomes premature; newborn; nutrition; outcome Low cost research
Obesity

Supervisor

Project Title

Theme

Keywords

Fee Band

Kim Edwards Obesogenic environments: combinations of features of the built environment associated with risk of obesityPDF file icon Obesity obesity; obesogenic environment; built environment; spatial epidemiology Low cost research
Kim Edwards Examining the ‘school effect’ on childhood obesityPDF file icon Obesity obesity; schools; obesogenic environment; spatial epidemiology; multilevel modelling; qualitative methods Low cost research
Michael Symonds/ Helen Budge Environmental regulation of brown adipose tissue functionPDF file icon Health and well being, imaging obesity; adipose tissue; development; growth Low cost lab-based research
Ophthalmology
Supervisor Project Title Theme Keywords Fee Band 
David Bates New treatments for age related macular degeneration PDF file icon Ophthalmolog Ophthalmology, angiogenesis, VEGF, RNA, splicing High cost lab-based research
David Bates Prevention of nerve loss in glacuoma by novel nerve growth factors  PDF file icon Ophthalmology Ophthalmology, neurodegeneration, VEGF, mitochondria High cost lab-based research
Platelets

Supervisor

Project Title

Theme

Keywords

Fee Band

Sue Fox/

Stan Heptinstall

Studies on the regulation of platelet function via measurements of VASP phosphorylation, a new marker of cAMP and cGMP elevation in platelets -- for Home & EU students/ International Students Measurement of VASP phosphorylation by flow cytometric bead assay to monitor platelet function and the modulatory effects of natural and pharmacological agents Platelets; blood cells; bead assay; flow cytometry; VASP; thrombosis Lab-based research

Sue Fox/

Stan Heptinstall 

Development and evaluation of a novel method for measurement of blood borne tissue factor and its relevance in both thrombosis and bleeding -- for Home & EU students/ International Students  Development and evaluation of a flow cytometric bead assay to measure tissue factor (TF) in platelets and monocytes, and in conjugates formed by these two blood cells  Platelets; blood cells; tissue factor; flow cytometry; thrombosis   Lab-based research
Reproductive endocrinology

Supervisor

Project Title

Theme

Keywords

Fee Band

David Bates

Control of breeding season by microvascular remodelling in the sheep PDF file icon Reproductive endocrinology Pituitary, vascular remodelling, reproduction, sheep, endocrinology Low-cost research
Respiratory Cell Biology

Supervisor

Project Title

Theme

Keywords

Fee Band

Simon Johnson and Debbie Clements Modelling Lymphangioleiomyomatosis with in vitro co-culture systemsPDF file icon Respiratory Cell Biology/Molecular pathology Cell culture; modelling; translational research

High cost lab-based research

Simon Johnson and Debbie Clements Expression and Activity of Matrix Metalloproteinases in lung remodellingPDF file icon Respiratory Cell Biology/Molecular Pathology Cell culture; modelling; translational research
Linhua Pang Role of bacteria and host interactions in lung inflammation in cystic fibrosis -- for Home & EU students/ International Students Respiratory cell and molecular biology Bacterial infection; lung inflammation; chemokines; cystic fibrosis; airway structural cells; myofibroblast differentiation; epigenetics; gene expression; pulmonary fibrosis Exceptional technically-intensive/specialised research projects with high consumable costs
Linhua Pang Molecular mechanisms of myofibroblast differentiation in pulmonary fibrosis -- for Home & EU students/ International Students Respiratory cell and molecular biology Bacterial infection; lung inflammation; chemokines; cystic fibrosis; airway structural cells; myofibroblast differentiation; epigenetics; gene expression; pulmonary fibrosis Exceptional technically-intensive/specialised research projects with high consumable costs
Rheumatology

Supervisor

Project Title

Theme

Keywords

Fee Band

Weiya Zhang and Michael Doherty Clinical phenotypes and predictors of progression of knee OsteoarthritisPDF file icon Rheumatology Osteoarthritis; subgroups; predictors and cohort study Low cost research
Stem Cells

Supervisor

Project Title

Theme

Keywords

Fee Band

Virginie Sottile Regulation of adult stem cell differentiation towards therapeutic cell lineages stem cell biology and differentiation stem cell biology, developmental biology, tissue engineering, regenerative medicine High cost laboratory-based research
Chris Denning Human induced pluripotent stem cell models of cardiovascular diseases for drug screening PDF file icon Stem Cells and Cardiovascular Disease Human induced pluripotent stem cells; disease modelling; cardiomyocytes; electrophysiology; drug and gene therapy High cost lab-based research
Chris Denning  Induced pluripotent stem cells to study genetic disorders of the heart PDF file icon   induced pluripotent stem cells; genetic disease of the heart; cardiomyocytes; drug screening; disease modelling High cost lab-based research
Stroke

Supervisor

Project Title

Theme

Keywords

Fee Band

Ulvi Bayraktutan  Elucidation of the mechanisms that account for neuroinflammation-mediated blood-brain barrier disruption following ischaemic stroke
(International students only)
 Stroke Blood-brain barrier; neuroinflammation; cytokines, oxidative stress; stroke High cost lab-based research
Philip Bath Acute stroke management - blood pressure control and antiplatelets Stroke Stroke; blood pressure; antihypertensive; antiplatelet Low cost research

 

(Updated: 18th Feb 2013)

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School of Clinical Sciences

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Queen's Medical Centre
Nottingham, NG7 2UH

telephone: +44 (0) 115 823 0695
fax: +44 (0) 115 823 0704
email: scs-enquiries@nottingham.ac.uk