Alexandra Brower

Contact

• workRoom B26 Veterinary Academic Building
  Sutton Bonington Campus
  Sutton Bonington
  Leicestershire
  LE12 5RD
  UK
• work0115 951 6425
• alexandra.brower@nottingham.ac.uk

Teaching Summary

A primary academic interest is in the development of contextual learning through comparative pathology; the concept being that when research and teaching are predicated on clinical cases (delivered… read more

Research Summary

Infectious Disease Primary interest: Epidemiology, fatty acid and molecular characteristics of Brucella canis.

Brower AI, K Homb, K Toohey-Kurth, O Okwumabua. Investigation of the Spread of Brucella canis via the U.S. Interstate Dog Trade. International Journal of Infectious Diseases, Volume 11 (5), pp. 454-458. 2007.

Brucella canis isolates variably produce 19:0 Cyclopropane, a potentially important indicator of strain origin and biologic behavior. Presented at The 59th Annual James H. Steele Conference on Diseases in Nature Transmissible to Man and the 64th International Conference on Diseases in Nature Communicable to Man 2nd Combined Meeting, Fort Worth, Texas. June 3rd, 2009.

Other topics: Avian pox virus, Bovine herpes virus, Salmonella, Cryptosporidium

Alexandra I. Brower, Francine Cigel, Craig Radi, Kathy Toohey-Kurth. Beak necrosis associated with bit application and avian poxvirus infection. Avian Pathology. Vol. 39(3), pp. 223-5. June 2010. Jun;39(3).

Brower AI, KM Homb, PN Bochsler, RE Porter, KL Woods, S Ubl, DA Krueger, FK Cigel and K Toohey-Kurth. Necrotizing Encephalitis in BHV-1 Aborted Fetuses. J. Vet. Diagn. Invest., Vol. 20 (3), pp. 297-303. May 2008.

Human and canine Salmonellosis associated with the practice of feeding raw '4D' meat. Presented at 65th INCDNCM Meeting, Symposium 5, University of Alaska, Fairbanks; Fairbanks, Alaska. August 10, 2010.

Brower AI, Cranfield MR. Cryptosporidium sp. - associated enteritis without gastritis in Rough Green Snakes (Opheodrys Aestivus) and a Common Garter Snake (Thamnophis sirtalis) Journal of Zoo and Wildlife Medicine: Vol. 32 (1), pp. 101-105. 2001.

Comparative Medicine Pulmonary vascular pathology in macaque models of pulmonary hypertension.

M. Patricia George, Alexandra Brower, Heather Kling, Tim Shipley, Jan Kristoff, Todd A. Reinhart, Michael Murphey-Corb, Mark T. Gladwin, Hunter C. Champion, Alison Morris, Karen A. Norris. AIDS Research and Human Retroviruses. -Not available-, ahead of print. doi:10.1089/aid.2009.0297.

Neuropathology White matter diseases in felids: demyelination associated with the consumption of irradiated diets and cheetah leukoencephalopathy.

Ian Duncan, Alexandra Brower, Yoichi Kondo, Joseph Curlee, Ronald Schultz. Extensive remyelination of the CNS can lead to functional recovery. Proceedings of the National Academy of Sciences. Vol. 106 (16), pp. 6832-6836. April 21, 2009. www.pnas.org/cgi/doi/10.1073/pnas.0812500106

Other topics: University of Wisconsin Digital Collections Neuropathology Project: currently in development.

Models of Education Outreach Wisconsin Health and Animal Science Initiative (WHASI) http://whasiprogram.org

Recent Publications

• BROWER, ALEXANDRA I, CIGEL, FRANCINE, RADI, CRAIG and TOOHEY-KURTH, KATHY, 2010. Beak necrosis in Hungarian partridges (Perdix perdix) associated with beak-bits and avian poxvirus infection. Avian Pathology. 39(3), 223-5
• M. PATRICIA GEORGE, ALEXANDRA BROWER, HEATHER KLING, TIM SHIPLEY, JAN KRISTOFF, TODD A. REINHART, MICHAEL MURPHEY-CORB, MARK T. GLADWIN, HUNTER C. CHAMPION, ALISON MORRIS, KAREN A. NORRIS, 2010. Pulmonary Vascular Lesions are Common in SIV- and SHIV-Env-infected Macaques AIDS Research and Human Retroviruses.. 26(12), ahead of print.
• IAN DUNCAN, ALEXANDRA BROWER, YOICHI KONDO, JOSEPH CURLEE, RONALD SCHULTZ., 2009. Extensive remyelination of the CNS can lead to functional recovery. Proceedings of the National Academy of Sciences. Neuroscience Early Edition. 106(16), 6832-6836
• BROWER, A, HOMB, KM, BOCHSLER, P, PORTER, R, WOODS, K, UBL, S, KRUEGER, D, CIGEL, F and TOOHEY-KURTH, K, 2008. Encephalitis In Aborted Bovine Fetuses Associated With Bovine Herpesvirus 1 Infection Journal Of Veterinary Diagnostic Investigation. 20(3), 297-303

• View all publications

A primary academic interest is in the development of contextual learning through comparative pathology; the concept being that when research and teaching are predicated on clinical cases (delivered in context), not only are they given unequivocal pragmatism and application, but ultimately veterinary medicine in the form of clinical service is greatly enhanced. A closely related research interest looks at finding and evaluating ways that the information and experiences generated from clinical practice can simultaneously involve and educate the public, with a particular focus on integrated programs that investigate the interaction between infectious diseases and human/animal communities. These endeavors are natural outgrowths of a clinically-based academic institution and application of this more holistic approach to veterinary science and pathology can open doors and make efficient use of resources, while having synergistic and far reaching effects. Information on an education outreach program that applies some of these concepts can be found at http://whasiprogram.org, and information on a fantastic zoonotic diseases group that holds a very welcoming annual conference can be found at http://sites.google.com/site/incdncm/Home

• BROWER, ALEXANDRA I, CIGEL, FRANCINE, RADI, CRAIG and TOOHEY-KURTH, KATHY, 2010. Beak necrosis in Hungarian partridges (Perdix perdix) associated with beak-bits and avian poxvirus infection. Avian Pathology. 39(3), 223-5
• M. PATRICIA GEORGE, ALEXANDRA BROWER, HEATHER KLING, TIM SHIPLEY, JAN KRISTOFF, TODD A. REINHART, MICHAEL MURPHEY-CORB, MARK T. GLADWIN, HUNTER C. CHAMPION, ALISON MORRIS, KAREN A. NORRIS, 2010. Pulmonary Vascular Lesions are Common in SIV- and SHIV-Env-infected Macaques AIDS Research and Human Retroviruses.. 26(12), ahead of print.
• IAN DUNCAN, ALEXANDRA BROWER, YOICHI KONDO, JOSEPH CURLEE, RONALD SCHULTZ., 2009. Extensive remyelination of the CNS can lead to functional recovery. Proceedings of the National Academy of Sciences. Neuroscience Early Edition. 106(16), 6832-6836
• BROWER, A, HOMB, KM, BOCHSLER, P, PORTER, R, WOODS, K, UBL, S, KRUEGER, D, CIGEL, F and TOOHEY-KURTH, K, 2008. Encephalitis In Aborted Bovine Fetuses Associated With Bovine Herpesvirus 1 Infection Journal Of Veterinary Diagnostic Investigation. 20(3), 297-303
• BROWER AI, K HOMB, K TOOHEY-KURTH, O OKWUMABUA., 2007. Investigation of the Spread of Brucella canis via the U.S. Interstate Dog Trade. International Journal of Infectious Diseases. 11(5), 454-458.
• BOWMAN, MICHELLE R, PARÉ, JEAN A, SIGLER, LYNNE, NAESER, JOHN P, SLADKY, KURT K, HANLEY, CHRIS S, HELMER, PETER, PHILLIPS, LYNETTE A, BROWER, ALEXANDRA and PORTER, ROBERT, 2007. Deep fungal dermatitis in three inland bearded dragons (Pogona vitticeps) caused by the Chrysosporium anamorph of Nannizziopsis vriesii. Medical mycology : official publication of the International Society for Human and Animal Mycology. 45(4), 371-6
• A. BROWER, L.V. HEROLD, B.M. KIRBY, 2006. Canine cardiac mesothelioma with granular cell morphology Veterinary Pathology. 43, 384-387
• A. BROWER, S. SALAMAT, P. MANLEY, J. CRAWFORD., 2005. Unilateral limb gigantism in a dog with a malignant peripheral nerve sheath tumor. Veterinary Pathology. 42(3), 53-56
• ALEXANDRA I. BROWER, KATHY KURTH, CRAIG RADI, DAVE KRUEGER, 2004. Feline panleukopenia: A diagnostic laboratory’s perspective Veterinary Medicine. 99(8), 714-721
• BROWER AI, CRANFIELD MR., 2001. Cryptosporidium sp. – associated enteritis without gastritis in Rough Green Snakes (Opheodrys Aestivus) and a Common Garter Snake (Thamnophis sirtalis) Journal of Zoo and Wildlife Medicine. 32(1), 101–105